公开(公告)号：US20130300419A1

公开(公告)日：2013-11-14

申请号：US13980794

申请日：2012-01-20

Applicant: Andrew D. Hibbs

Inventor： Andrew D. Hibbs

IPC: G01V3/08

CPC classification number: G01V3/088 ,  G01R15/165

Abstract: Methods, systems, and apparatuses for measuring an electric potential in the earth, which includes a first sensor are disclosed. The first sensor includes a sensing plate for placement in an environment in close proximity to the earth. The sensing plate has an operative capacitive coupling with the earth and measures the earth's electric potential. The sensor also includes a barrier providing electrochemical segregation between the sensing plate and the earth and an amplifier having at least one stage for receiving and amplifying a first signal carrying the potential measured by the sensing plate. The sensor also includes a first connection carrying the first signal from the sensing plate to the amplifier; and a reference voltage for application to the first stage of the amplifier, the reference voltage providing a reference against which the potential measured by the sensing plate is compared. Other embodiments are described and claimed.

Abstract translation: 公开了用于测量地球中的电位的方法，系统和装置，其包括第一传感器。 第一传感器包括用于放置在靠近地球的环境中的感测板。 感测板具有与地球的可操作电容耦合并测量地球的电位。 传感器还包括提供感测板和地球之间的电化学隔离的屏障和具有至少一个级的放大器，用于接收和放大承载由感测板测量的电位的第一信号。 传感器还包括承载从感测板到放大器的第一信号的第一连接; 以及用于施加到放大器的第一级的参考电压，参考电压提供用于比较由感测板测量的电位的参考电压。 描述和要求保护其他实施例。

公开(公告)号：US20120310543A1

公开(公告)日：2012-12-06

申请号：US13538537

申请日：2012-06-29

Applicant: Andrew D. Hibbs ,  Geoffrey Alden Barrall ,  Daniel K. Lathrop

Inventor： Andrew D. Hibbs ,  Geoffrey Alden Barrall ,  Daniel K. Lathrop

IPC: G06F19/10

CPC classification number: G01N33/48721 ,  C12Q1/68 ,  C12Q1/6869 ,  C12Q2565/631

Abstract: The sequencing of individual monomers (e.g., a single nucleotide) of a polymer (e.g., DNA, RNA) is improved by reducing the motion of the polymer due to thermally-driven diffusion to reduce the spatial error in the position of the polymer within a measurement device. A major system parameter, such as average translocation velocity or measurement time, is selected based on the characteristics of the sensing system utilized, and an algorithm jointly optimizes the sequencing order error rate and the monomer identification error rate of the system.

Abstract translation: 聚合物（例如，DNA，RNA）的单个单体（例如，单个核苷酸）的测序通过由于热驱动扩散而减少聚合物的运动来改善，以减少聚合物内部位置的空间误差 测量装置。 基于所使用的感测系统的特征，选择平均易位速度或测量时间等主要系统参数，并且一个算法联合优化了系统的排序顺序错误率和单体识别错误率。

公开(公告)号：US20090071824A1

公开(公告)日：2009-03-19

申请号：US11664992

申请日：2005-10-14

Applicant: Andrew D. Hibbs ,  Regina E. Dugan ,  Michael Andrew Krupka

Inventor： Andrew D. Hibbs ,  Regina E. Dugan ,  Michael Andrew Krupka

IPC: G01N27/26

CPC classification number: G01N33/48728

Abstract: An integrated array of electronic sensing elements outputs a bio-fingerprint of an analyte. System is preferably constructed of as a series of three layers but need not be so arranged. An upper layer defines a fluid volume or analyte chamber; a middle layer contains the sensing elements; and a third layer contains electronic readout elements. The analyte chamber contains an electrolyte and the analyte to be detected. The sensing elements are optimized for maximum detection sensitivity in the minimum response time. The response of each sensing element is read out by a dedicated sensing electrode. Around each electrode is a control ring. The potential of the control ring is set to attract analytes of interest to the sensing elements.

Abstract translation: 电子感应元件的集成阵列输出分析物的生物指纹图谱。 系统优选地由一系列三层构成，但不必如此设置。 上层限定流体体积或分析物室; 中间层包含传感元件; 并且第三层包含电子读出元件。 分析物室含有电解质和待检测的分析物。 针对最小响应时间的最大检测灵敏度优化了传感元件。 每个感测元件的响应由专用感测电极读出。 每个电极周围都是一个控制环。 设置控制环的电位以吸引感测元件感兴趣的分析物。

公开(公告)号：US20080246485A1

公开(公告)日：2008-10-09

申请号：US12000234

申请日：2007-12-11

Applicant: Andrew D. Hibbs ,  Thomas Kurt Nielsen

Inventor： Andrew D. Hibbs ,  Thomas Kurt Nielsen

IPC: G01V3/10

CPC classification number: G01R33/12 ,  G01R29/0871 ,  G01R33/04 ,  G01R33/10 ,  G01V3/02 ,  G01V3/08 ,  G01V3/083 ,  H03F2200/261 ,  H03F2203/45138 ,  Y02A90/344

Abstract: An underwater EM measurement system, which is substantially smaller, much simpler to use, and more robust than prior systems, is formed as a sensor package integrated into a single pressure vessel includes two magnetic sensors including induction coils disposed substantially horizontally so as to measure fields in orthogonal directions. The package also includes two electric field sensors including electric potential antennas adapted to couple to a water potential via a capacitive electrode having a conducting material and an electrically insulative layer formed of an insulating material. The capacitive electrode has a capacitance to the medium of greater than 1 mF. Preferably, the insulating material is a metal oxide.

Abstract translation: 形成了比现有系统简单得多并且比现有系统更健壮的水下EM测量系统，其集成到单个压力容器中的传感器封装包括两个磁性传感器，包括基本上水平设置的感应线圈，以便测量场 在正交方向。 封装还包括两个电场传感器，包括适于通过具有导电材料的电容电极和由绝缘材料形成的电绝缘层耦合到水势的电势天线。 电容电极具有大于1mF的介质的电容。 优选地，绝缘材料是金属氧化物。

公开(公告)号：US10082546B2

公开(公告)日：2018-09-25

申请号：US12000234

申请日：2007-12-11

Applicant: Andrew D. Hibbs ,  Thomas Kurt Nielsen

Inventor： Andrew D. Hibbs ,  Thomas Kurt Nielsen

IPC: G01V3/02 ,  G01R33/12 ,  G01V3/08 ,  G01R33/04 ,  G01R33/10 ,  G01R29/08

CPC classification number: G01R33/12 ,  G01R29/0871 ,  G01R33/04 ,  G01R33/10 ,  G01V3/02 ,  G01V3/08 ,  G01V3/083 ,  H03F2200/261 ,  H03F2203/45138 ,  Y02A90/344

Abstract: An underwater EM measurement system, which is substantially smaller, much simpler to use, and more robust than prior systems, is formed as a sensor package integrated into a single pressure vessel includes two magnetic sensors including induction coils disposed substantially horizontally so as to measure fields in orthogonal directions. The package also includes two electric field sensors including electric potential antennas adapted to couple to a water potential via a capacitive electrode having a conducting material and an electrically insulative layer formed of an insulating material. The capacitive electrode has a capacitance to the medium of greater than 1 mF. Preferably, the insulating material is a metal oxide.

公开(公告)号：US09405032B2

公开(公告)日：2016-08-02

申请号：US13980794

申请日：2012-01-20

Applicant: Andrew D. Hibbs

Inventor： Andrew D. Hibbs

IPC: G01V3/08 ,  G01R15/16

CPC classification number: G01V3/088 ,  G01R15/165

Abstract: Methods, systems, and apparatuses for measuring an electric potential in the earth, which includes a first sensor are disclosed. The first sensor includes a sensing plate for placement in an environment in close proximity to the earth. The sensing plate has an operative capacitive coupling with the earth and measures the earth's electric potential. The sensor also includes a barrier providing electrochemical segregation between the sensing plate and the earth and an amplifier having at least one stage for receiving and amplifying a first signal carrying the potential measured by the sensing plate. The sensor also includes a first connection carrying the first signal from the sensing plate to the amplifier; and a reference voltage for application to the first stage of the amplifier, the reference voltage providing a reference against which the potential measured by the sensing plate is compared. Other embodiments are described and claimed.

Abstract translation: 公开了用于测量地球中的电位的方法，系统和装置，其包括第一传感器。 第一传感器包括用于放置在靠近地球的环境中的感测板。 感测板具有与地球的可操作电容耦合并测量地球的电位。 传感器还包括提供感测板和地球之间的电化学隔离的屏障和具有至少一个级的放大器，用于接收和放大承载由感测板测量的电位的第一信号。 传感器还包括承载从感测板到放大器的第一信号的第一连接; 以及用于施加到放大器的第一级的参考电压，参考电压提供用于比较由感测板测量的电位的参考电压。 描述和要求保护其他实施例。

公开(公告)号：US08103328B2

公开(公告)日：2012-01-24

申请号：US12243461

申请日：2008-10-01

Applicant: Peter James Turner ,  Robert Matthews ,  Jamison Scott Woodward ,  Konstantine V. Ermolaev ,  Andrew D. Hibbs

Inventor： Peter James Turner ,  Robert Matthews ,  Jamison Scott Woodward ,  Konstantine V. Ermolaev ,  Andrew D. Hibbs

IPC: A61B5/0478 ,  A61B19/00

CPC classification number: A61B5/0478 ,  A61B5/0002

Abstract: A self-locating mounting apparatus for holding objects such as sensors at specific positions on a subject's head includes a central mount constituted by a plurality of inextensible elements adapted to fit over the top of a subject's head. In addition, the mounting apparatus includes an adjustable circumferential band adapted to circle the subject's head and connect the central mount to inextensible side elements via sliding joints. A plurality of biasing elements provide a force for biasing sensor mounting units on the mounting apparatus against a subject's head, allowing for long-term sensing while minimizing interference forces on the mounting units. Advantageously, the mounting apparatus holds sensors within approximately 5 mm of their desired measurement positions over a range of subject head sizes.

Abstract translation: 用于将诸如传感器等物体保持在被检者头部的特定位置的自定位安装装置包括：由多个不可伸展元件构成的中央支座，适合于配合在被检者头部的顶部。 此外，安装设备包括可调节的环形带，其适于使被检者的头部圆形并且通过滑动接头将中央安装件连接到不可伸展的侧部元件。 多个偏置元件提供用于将安装装置上的传感器安装单元偏压抵靠对象的头部的力，允许长期检测，同时最小化安装单元上的干扰力。 有利地，安装装置将传感器保持在其目标头部尺寸范围内的所需测量位置的大约5mm的范围内。

公开(公告)号：US20100148789A1

公开(公告)日：2010-06-17

申请号：US11992309

申请日：2005-09-22

Applicant: Andrew D. Hibbs ,  Micheal Andrew Krupka ,  Robert Matthews ,  Linas Kunstmanas

Inventor： Andrew D. Hibbs ,  Micheal Andrew Krupka ,  Robert Matthews ,  Linas Kunstmanas

IPC: G01N27/02 ,  G01R19/00

CPC classification number: G01N33/5438 ,  G01N33/48728

Abstract: A non-invasive measurement system (110) for measuring the electrical potential of a voltage source (20, 120) includes a sensing electrode (50, 151) spaced from the voltage source (20, 120). Preferably the voltage source (20, 120) is within a biological cell (115) located in a nutrient bath (119) including electrolytic medium (117) and an object (30, 190) is a portion of the electrolytic fluid (117) located between the cell (115) and the sensing electrode (50, 151). A feedback electrode (181) is formed in an annular shape and surrounds the sensing electrode (50, 151) thus creating an annular fluid region therebetween. The value of the voltage in the annular region (131) is set substantially equal to the value of the voltage in the object (190) and therefore the impedance between the object (190) and a stray voltage source (40) is maximized.

Abstract translation: 用于测量电压源（20,120）的电位的非侵入性测量系统（110）包括与电压源（20,120）间隔开的感测电极（50,151）。 优选地，电压源（20,120）在位于包括电解介质（117）的营养浴（119）内的生物细胞（115）内，物体（30,190）是电解液（117）的一部分 在电池（115）和感测电极（50,151）之间。 反馈电极（181）形成为环状并且围绕感测电极（50,151），从而在它们之间产生环形流体区域。 环状区域（131）中的电压值被设定为基本上等于物体（190）中的电压值，因此物体（190）和杂散电压源（40）之间的阻抗最大化。

公开(公告)号：US20090222216A1

公开(公告)日：2009-09-03

申请号：US12395682

申请日：2009-03-01

Applicant: Andrew D. Hibbs ,  Geoffrey Alden Barrall ,  Daniel K. Lathrop

Inventor： Andrew D. Hibbs ,  Geoffrey Alden Barrall ,  Daniel K. Lathrop

IPC: G06F19/00 ,  G01R33/48

CPC classification number: G01N33/48721 ,  C12Q1/68 ,  C12Q1/6869 ,  C12Q2565/631

Abstract: The sequencing of individual monomers (e.g., a single nucleotide) of a polymer (e.g., DNA, RNA) is improved by reducing the motion of the polymer due to thermally-driven diffusion to reduce the spatial error in the position of the polymer within a measurement device. A major system parameter, such as average translocation velocity or measurement time, is selected based on the characteristics of the sensing system utilized, and an algorithm jointly optimizes the sequencing order error rate and the monomer identification error rate of the system.

Abstract translation: 聚合物（例如，DNA，RNA）的单个单体（例如，单个核苷酸）的测序通过由于热驱动扩散而减少聚合物的运动来改善，以减少聚合物内的位置的空间误差 测量装置。 基于所使用的感测系统的特征，选择平均易位速度或测量时间等主要系统参数，并且一个算法联合优化了系统的排序顺序错误率和单体识别错误率。

公开(公告)号：US20090088619A1

公开(公告)日：2009-04-02

申请号：US12243461

申请日：2008-10-01

Applicant: Peter James Turner ,  Robert Matthews ,  Jamison Scott Woodward ,  Konstantine V. Ermolaev ,  Andrew D. Hibbs

Inventor： Peter James Turner ,  Robert Matthews ,  Jamison Scott Woodward ,  Konstantine V. Ermolaev ,  Andrew D. Hibbs

IPC: A61B5/0476 ,  A61B5/00

CPC classification number: A61B5/0478 ,  A61B5/0002

Abstract: A self-locating mounting apparatus for holding objects such as sensors at specific positions on a subject's head includes a central mount constituted by a plurality of inextensible elements adapted to fit over the top of a subject's head. In addition, the mounting apparatus includes an adjustable circumferential band adapted to circle the subject's head and connect the central mount to inextensible side elements via sliding joints. A plurality of biasing elements provide a force for biasing sensor mounting units on the mounting apparatus against a subject's head, allowing for long-term sensing while minimizing interference forces on the mounting units. Advantageously, the mounting apparatus holds sensors within approximately 5 mm of their desired measurement positions over a range of subject head sizes.

Abstract translation: 用于将诸如传感器等物体保持在被检者头部的特定位置的自定位安装装置包括：由多个不可伸展元件构成的中央支座，适合于配合在被检者头部的顶部。 此外，安装设备包括可调节的环形带，其适于使被检者的头部圆形并且通过滑动接头将中央安装件连接到不可伸展的侧部元件。 多个偏置元件提供用于将安装装置上的传感器安装单元偏压抵靠对象的头部的力，允许长期检测，同时最小化安装单元上的干扰力。 有利地，安装装置将传感器保持在其目标头部尺寸范围内的所需测量位置的大约5mm的范围内。