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1.发明申请Multi-aperture single photon emission computed tomography (SPECT) imaging apparatus 有权多孔单光子发射计算机断层扫描（SPECT）成像装置公开(公告)号：US20080116386A1
公开(公告)日：2008-05-22
申请号：US11985820
申请日：2007-11-16
IPC分类号： G01T1/24
CPC分类号： G01T1/1648 , G01T1/249
摘要： Methods and systems for improving image quality of single photon nuclear imaging systems, such as single photon emission computed tomography (SPECT) systems for imaging of an object under study, such as small objects including small animals of different sizes using synthetic apertures. The methods and systems include processes and instrumentations for high-resolution, high detection efficiency leading to lower image noise and artifact-free synthetic aperture single photon nuclear images, such as SPECT images. Also, the method and systems provide design parameters, hardware settings, and data acquisition processes for optimal imaging of objects having different sizes.
摘要翻译： 用于改善单光子核成像系统的图像质量的方法和系统，例如用于对所研究对象成像的单光子发射计算机断层摄影（SPECT）系统，诸如使用合成孔径的小物体，包括不同尺寸的小动物。 方法和系统包括用于高分辨率，高检测效率的过程和仪器，导致较低的图像噪声和无伪影的合成孔径单光子核图像，例如SPECT图像。 此外，该方法和系统提供用于具有不同尺寸的对象的最佳成像的设计参数，硬件设置和数据采集过程。
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2.发明授权Method and apparatus for fabricating mercuric iodide polycrystalline films for digital radiography 有权用于制造数字射线照相的碘化汞多晶膜的方法和装置公开(公告)号：US07186985B2
公开(公告)日：2007-03-06
申请号：US10158494
申请日：2002-05-30
申请人： Jan S. Iwanczyk , Bradley E. Patt
发明人： Jan S. Iwanczyk , Bradley E. Patt
IPC分类号： G01T1/24
CPC分类号： H01L27/14676 , C23C14/0694 , C23C14/24 , C23C14/564 , H01L31/115 , H04N5/32
摘要： A method is provided for fabricating in a thermal evaporation system a polycrystalline film capable of directly detecting radiation. Source material is placed in a container, and the container is evacuated to create vacuum within the container. The source material is heated to evaporate the source material for depositing on a substrate. The polycrystalline film is used in as deposited form to detect the radiation.
摘要翻译： 提供了一种用于在热蒸发系统中制造能够直接检测辐射的多晶膜的方法。 将源材料放置在容器中，并将容器抽空以在容器内产生真空。 将源材料加热以蒸发源材料以沉积在基底上。 多晶膜以沉积形式使用以检测辐射。
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公开(公告)号：US07170049B2
公开(公告)日：2007-01-30
申请号：US11024317
申请日：2004-12-28
申请人： Jan S. Iwanczyk , Bradley E. Patt , Einar Nygard
发明人： Jan S. Iwanczyk , Bradley E. Patt , Einar Nygard
IPC分类号： H01J40/14
CPC分类号： G01T1/2928 , H01L27/14618 , H01L27/14634 , H01L27/14658 , H01L27/14661 , H01L27/14696 , H01L31/0296 , H01L2224/16225 , H01L2224/48091 , H01L2224/48227 , H01L2224/48472 , H01L2924/15174 , H01L2924/15184 , H01L2924/15311 , H01L2924/00014 , H01L2924/00
摘要： A radiation detector for detecting radiation such as x-rays. The radiation detector includes a detector having a plurality of pixels, wherein each of the pixels is used for detecting the radiation. The radiation detector also includes a ball grid array (BGA) package having a plurality of solder balls formed on a first side and a plurality of contacts formed on a second side. The BGA package also has a cavity, in which at least one integrated circuit (IC) chip is mounted. The IC chip has a plurality of readout channels, each of the readout channels being coupled to a corresponding one of the pixels via a corresponding one of the solder balls to receive an electrical signal corresponding to the radiation detected by the corresponding one of the pixels.
摘要翻译： 用于检测诸如x射线的辐射的辐射检测器。 辐射检测器包括具有多个像素的检测器，其中每个像素用于检测辐射。 辐射检测器还包括具有形成在第一侧上的多个焊球和形成在第二侧上的多个触点的球栅阵列（BGA）封装。 BGA封装还具有一个空腔，其中安装有至少一个集成电路（IC）芯片。 IC芯片具有多个读出通道，每个读出通道经由相应的一个焊球耦合到相应的一个像素，以接收对应于由相应的一个像素检测到的辐射的电信号。
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公开(公告)号：US07328058B2
公开(公告)日：2008-02-05
申请号：US09754103
申请日：2001-01-03
CPC分类号： A61B6/4057 , A61B6/425 , A61B6/4258 , G01T1/161
摘要： An apparatus for intravascular imaging to detect and characterize early-stage, unstable coronary arty plaques. The detector works by identifying and localizing plaque-binding beta-emitting radiopharmaceuticals.
摘要翻译： 用于血管内成像的装置，用于检测和表征早期，不稳定的冠状动脉斑块。 检测器通过识别和定位斑块结合的β发射放射性药物来起作用。
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公开(公告)号：US06377838B1
公开(公告)日：2002-04-23
申请号：US09326204
申请日：1999-06-04
申请人： Jan S. Iwanczyk , Bradley E. Patt
发明人： Jan S. Iwanczyk , Bradley E. Patt
IPC分类号： A61B600
CPC分类号： A61B6/0414 , A61B6/4258 , A61B6/508
摘要： A method and apparatus are provided for examining the breast for suspicious lesions. The apparatus includes a gamma-ray camera and an attachment mechanism for incorporating the gamma-ray camera as part of the breast compression fixture. The gamma-ray camera is both part of the breast compression fixture and a gamma-ray imaging system for providing an image of radiotracer distribution in the breast. The apparatus for incorporating the gamma-ray camera into the breast compression fixture assures minimum distance between the lesion in the compressed breast tissue and the gamma-ray camera. All unnecessary materials are removed from between the compressed breast and the gamma-ray camera. The apparatus also allows for positioning of the breast in different manners between the imaging sessions to obtain multiple projection views of the breast and to view the lesion with the least separation from the detector. The small camera when positioned directly against the breast allows for breast imaging without the remainder of the body in the background. The apparatus allows for the alignment of the breast and the gamma camera head in a fixed position during each imaging session. Typical views of the breast taken with the apparatus are similar to those used in mammographic projections. The attachment mechanism includes an electrical connector matching a mating connector on the mammography machine in order to enable the compression mechanism.
摘要翻译： 提供了一种检查乳房可疑病变的方法和装置。 该装置包括伽马射线照相机和用于将伽马射线相机作为乳房压缩夹具的一部分并入的附接机构。 伽马射线照相机是乳房压缩夹具的一部分和用于在乳房中提供放射性示踪剂分布的图像的伽马射线成像系统。 用于将伽马射线照相机并入乳房压缩夹具的装置确保压缩的乳房组织中的病变与γ射线照相机之间的最小距离。 所有不必要的材料从被压缩的乳房和伽马射线照相机之间移除。 该装置还允许在成像会话之间以不同的方式定位乳房，以获得乳房的多个投影视图并且以与检测器的最小分离来观察病变。 当小型摄像机直接对着乳房进行定位时，可以在背景中进行乳房成像，而不需要身体剩余部分。 该装置允许在每个成像会话期间将乳房和伽马相机头对准在固定位置。 用该装置拍摄的乳房的典型视图类似于乳房X线照相术投影中使用的乳房。 附接机构包括与乳房X线照相机上的匹配连接器匹配的电连接器，以实现压缩机构。
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公开(公告)号：US08368029B2
公开(公告)日：2013-02-05
申请号：US13317219
申请日：2011-10-11
IPC分类号： G01T1/24
CPC分类号： G01T1/1603 , G01R33/481 , G01T1/249
摘要： A multi-modality imaging system for imaging of an object under study, e.g., a whole body or parts of the body of animals such as humans, other primates, swine, dogs, or rodents, that includes a magnetic resonance imaging apparatus and a cadmium zinc telluride (CZT)-family semiconductor, single-photon imaging apparatus within a magnetic field produced by the magnetic resonance imaging apparatus such that sequential or simultaneous imaging can be done with the two modalities using the same support bed of the object under study in the same, uninterrupted imaging session.
摘要翻译： 一种用于对所研究对象成像的多模态成像系统，例如动物的整个身体或身体的一部分，例如人，其他灵长类动物，猪，狗或啮齿动物，其包括磁共振成像装置和镉 锌碲化物（CZT） - 家族半导体，由磁共振成像装置产生的磁场内的单光子成像装置，使得可以使用两种模式进行连续或同时成像，所述两种模式使用在研究中的对象的相同支撑床 相同的，不间断的成像会话。
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公开(公告)号：US20120035465A1
公开(公告)日：2012-02-09
申请号：US13317219
申请日：2011-10-11
CPC分类号： G01T1/1603 , G01R33/481 , G01T1/249
摘要： A multi-modality imaging system for imaging of an object under study, e.g., a whole body or parts of the body of animals such as humans, other primates, swine, dogs, or rodents, that includes a magnetic resonance imaging apparatus and a cadmium zinc telluride (CZT)-family semiconductor, single-photon imaging apparatus within a magnetic field produced by the magnetic resonance imaging apparatus such that sequential or simultaneous imaging can be done with the two modalities using the same support bed of the object under study in the same, uninterrupted imaging session.
摘要翻译： 一种用于对所研究对象成像的多模态成像系统，例如动物的整个身体或身体的一部分，例如人，其他灵长类动物，猪，狗或啮齿动物，其包括磁共振成像装置和镉 锌碲化物（CZT） - 家族半导体，由磁共振成像装置产生的磁场内的单光子成像装置，使得可以使用两种模式进行连续或同时成像，所述两种模式使用在研究中的对象的相同支撑床 相同的，不间断的成像会话。
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8.发明授权Multi-aperture single photon emission computed tomography (SPECT) imaging apparatus 有权多孔单光子发射计算机断层扫描（SPECT）成像装置公开(公告)号：US07786444B2
公开(公告)日：2010-08-31
申请号：US11985820
申请日：2007-11-16
IPC分类号： G01T1/166
CPC分类号： G01T1/1648 , G01T1/249
摘要： Methods and systems for improving image quality of single photon nuclear imaging systems, such as single photon emission computed tomography (SPECT) systems for imaging of an object under study, such as small objects including small animals of different sizes using synthetic apertures. The methods and systems include processes and instrumentations for high-resolution, high detection efficiency leading to lower image noise and artifact-free synthetic aperture single photon nuclear images, such as SPECT images. Also, the method and systems provide design parameters, hardware settings, and data acquisition processes for optimal imaging of objects having different sizes.
摘要翻译： 用于改善单光子核成像系统的图像质量的方法和系统，例如用于对所研究对象成像的单光子发射计算机断层摄影（SPECT）系统，诸如使用合成孔径的小物体，包括不同尺寸的小动物。 方法和系统包括用于高分辨率，高检测效率的过程和仪器，导致较低的图像噪声和无伪影的合成孔径单光子核图像，例如SPECT图像。 此外，该方法和系统提供用于具有不同尺寸的对象的最佳成像的设计参数，硬件设置和数据采集过程。
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公开(公告)号：US06771802B1
公开(公告)日：2004-08-03
申请号：US09585585
申请日：2000-06-02
IPC分类号： G06K900
CPC分类号： G01T1/161 , A61B6/4258
摘要： An imaging probe system includes a portable imaging gamma ray probe and a computer, and is used to locate and examine the distribution of radiation concentrated in animal tissue. The imaging probe system can operate in an imaging mode, a non-imaging mode (simple counting mode), or both simultaneously. The imaging probe system may include smart algorithms that analyze subdivisions of the images and indicate to the user via an audio indicator, a visual indicator, or both, the presence of one or more high-density concentrations of radiation within the image. The determination of such concentrations is governed either spatial resolution requirements of the subdivided image, or based on statistical variations of the cumulative number of particles detected. The imaging probe can also display the count of the detected radioactivity. The frequency of the audio output may be varied in proportion to the count rate and modulating the frequency, volume, phase or stereo panning of the audio output indicates the presence of more than one source in the field of view. By replacing the collimator of the imaging probe, the user is allowed to vary imaging parameters including variable spatial resolution, sensitivity and field of view.
摘要翻译： 成像探针系统包括便携式成像伽马射线探针和计算机，并用于定位和检查集中在动物组织中的辐射分布。 成像探针系统可以以成像模式，非成像模式（简单计数模式）或同时两者操作。 成像探针系统可以包括智能算法，其分析图像的细分并且经由音频指示符，视觉指示符或两者指示用户在图像内存在一个或多个高密度的辐射浓度。 这种浓度的确定决定了细分图像的空间分辨率要求，或者基于所检测的颗粒的累积数量的统计变化。 成像探针也可以显示检测到的放射性的数量。 音频输出的频率可以与计数速率成比例地变化，并且调制音频输出的频率，音量，相位或立体声平移指示在视野中存在多于一个的源。 通过更换成像探针的准直仪，允许用户改变成像参数，包括可变的空间分辨率，灵敏度和视野。
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公开(公告)号：US06713768B2
公开(公告)日：2004-03-30
申请号：US09835937
申请日：2001-04-16
申请人： Jan S. Iwanczyk , Bradley E. Patt , Carolyn Tull
发明人： Jan S. Iwanczyk , Bradley E. Patt , Carolyn Tull
IPC分类号： G01T124
CPC分类号： H01L31/103 , H01L27/1463 , H01L27/14658
摘要： A junction-side illuminated detector array of pixelated detectors is constructed on a silicon wafer. A junction contact on the front-side may cover the whole detector array, and may be used as an entrance window for light, x-ray, gamma ray and/or other particles. The back-side has an array of individual ohmic contact pixels. Each of the ohmic contact pixels on the back-side may be surrounded by a grid or a ring of junction separation implants. Effective pixel size may be changed by separately biasing different sections of the grid. A scintillator may be coupled directly to the entrance window while readout electronics may be coupled directly to the ohmic contact pixels. The detector array may be used as a radiation hardened detector for high-energy physics research or as avalanche imaging arrays.
摘要翻译： 像素化检测器的结侧照明检测器阵列构造在硅晶片上。 前侧的连接点可以覆盖整个检测器阵列，并且可以用作光，x射线，γ射线和/或其它粒子的入口窗口。 背面具有单独的欧姆接触像素阵列。 背侧上的每个欧姆接触像素可以被栅格或结分离植入环形围绕。 可以通过单独偏置网格的不同部分来改变有效的像素大小。 闪烁体可以直接耦合到入口窗口，而读出电路可以直接耦合到欧姆接触像素。 检测器阵列可用作用于高能物理研究的辐射硬化检测器，或用作雪崩成像阵列。
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