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公开(公告)号:US20060210996A1
公开(公告)日:2006-09-21
申请号:US11082006
申请日:2005-03-15
申请人: Eric Leproust , Bill Peck , Bruce Maeda
发明人: Eric Leproust , Bill Peck , Bruce Maeda
CPC分类号: G01N33/6845 , B01J19/0046 , B01J2219/00286 , B01J2219/00353 , B01J2219/00378 , B01J2219/00527 , B01J2219/00608 , B01J2219/0061 , B01J2219/00612 , B01J2219/00626 , B01J2219/00637 , B01J2219/00659 , B01J2219/00711 , B01J2219/00722 , B01J2219/00725 , B82Y30/00 , G01N33/552 , G01N2035/00158 , G01N2035/0437
摘要: Methods and devices for producing chemical arrays are provided. Aspects of methods include employing a dedicated wash fluid reaction chamber. In certain embodiments, aspects include contacting a surface with at least a deblocking reagent to produce a deblocked surface, washing the deblocked surface in a dedicated wash fluid reaction chamber, e.g., flow cell, and then contacting the washed surface with one or more reactive moieties in a spatially controlled manner. Also provided are devices configured for use in practicing the subject methods.
摘要翻译: 提供了生产化学阵列的方法和装置。 方法的方面包括采用专用洗涤液反应室。 在某些实施方案中,方面包括使表面与至少一个去块试剂接触以产生去封闭的表面,在专用洗涤流体反应室(例如流动池)中洗涤去封闭的表面,然后使洗涤的表面与一个或多个反应性部分 以空间控制的方式。 还提供了被配置为用于实践主题方法的设备。