公开(公告)号：US20170279798A1

公开(公告)日：2017-09-28

申请号：US15470808

申请日：2017-03-27

申请人： Matthew C. Reynolds

发明人： Matthew C. Reynolds

IPC分类号： H04L29/06 ,  H04L9/32

CPC分类号： H04L63/0853 ,  G06F21/35 ,  G06F21/42 ,  H04L9/3234 ,  H04L9/3271 ,  H04L63/08 ,  H04L63/10 ,  H04L63/107 ,  H04L63/18 ,  H04L2209/80 ,  H04L2463/082 ,  H04W12/00503 ,  H04W12/06

摘要： To authorize a client device to access a secure resource hosted on a web server, the present methods and systems may provide executable instructions including a challenge token to the client device, which, in turn, may cause the client device to provide executable instructions, including the challenge token, to a mobile client device via a persona area network. The executable instructions provided to the mobile client device may request the mobile client device to return a verification token. The mobile client device may compare the provided challenge token to a challenge token stored locally. If the challenge tokens match, the mobile client device may provide a verification token to the client device via the personal area network, which may in turn provide the verification token to the web server. The web server may compare the verification token provided by the client device to a verification token provided by the present methods and systems. If the verification tokens match, the web server may authorize the access to the secure resource.

公开(公告)号：US09704165B2

公开(公告)日：2017-07-11

申请号：US13105713

申请日：2011-05-11

申请人： James V. Anderson ,  John B. Nolt ,  Michael J. Strutton ,  Wenchang Yan ,  Sriti Kumar ,  Robert M. Maury ,  Paul M. Broft ,  Maria F. Arscott ,  Nancy M. Lim ,  Jason C. Reynolds ,  Joe Kearney ,  John Schult ,  Melinda M. Weathers ,  Chad Estes ,  Erica M. Stanley ,  Geoffrey Hom ,  Gregory K. Dunn ,  Horace Williams, II ,  Matt White ,  Reginald R. Bradford ,  Andrei Erdoss ,  Andrew Robert Dorr ,  Brian Culler

发明人： James V. Anderson ,  John B. Nolt ,  Michael J. Strutton ,  Wenchang Yan ,  Sriti Kumar ,  Robert M. Maury ,  Paul M. Broft ,  Maria F. Arscott ,  Nancy M. Lim ,  Jason C. Reynolds ,  Joe Kearney ,  John Schult ,  Melinda M. Weathers ,  Chad Estes ,  Erica M. Stanley ,  Geoffrey Hom ,  Gregory K. Dunn ,  Horace Williams, II ,  Matt White ,  Reginald R. Bradford ,  Andrei Erdoss ,  Andrew Robert Dorr ,  Brian Culler

IPC分类号： G06F15/16 ,  G06Q30/02 ,  H04L12/26 ,  G06Q10/06 ,  G06Q10/10 ,  G06Q50/00 ,  H04L29/08

CPC分类号： G06Q30/02 ,  G06Q10/06 ,  G06Q10/107 ,  G06Q50/01 ,  H04L43/02 ,  H04L43/04 ,  H04L67/22

摘要： Systems and methods for evaluating the effectiveness of social media pages. Users of social media systems review and publish various kinds of content on social media pages, including various messages, audio clips, video clips, polls, web links, etc. A social media page evaluation system hosted on a physical server or a cloud receives a social media page that is to be evaluated, and provides results of an evaluation process. The evaluation process involves processing of various criteria and parameters that characterize engagements and interactions between users of social media pages. Results of an evaluation process include qualitative and quantitative attributes in connection with evaluating the effectiveness of published content on social media pages. Such results are useful for purposes of enriching content in social media pages, resulting in greater network traffic due to increased engagements and interaction among users of social media pages.

公开(公告)号：US09433621B2

公开(公告)日：2016-09-06

申请号：US13579399

申请日：2011-02-18

申请人： Ashok Arasappan ,  F. George Njoroge ,  Cecil D. Kwong ,  Subramaniam Ananthan ,  Frank Bennett ,  Francisco Velazquez ,  Vinay M. Girijavallabhan ,  Yuhua Huang ,  Hollis S. Kezar, III ,  Joseph A. Maddry ,  Robert C. Reynolds ,  Abhijit Roychowdhury ,  Anita T. Fowler ,  John A. Secrist, III ,  Joseph A. Kozlowski ,  Bandarpalle B. Shankar ,  Ling Tong ,  Seong Heon Kim ,  Malcolm MacCoss ,  Srikanth Venkatraman ,  Vishal Verma

发明人： Ashok Arasappan ,  F. George Njoroge ,  Cecil D. Kwong ,  Subramaniam Ananthan ,  Frank Bennett ,  Francisco Velazquez ,  Vinay M. Girijavallabhan ,  Yuhua Huang ,  Hollis S. Kezar, III ,  Joseph A. Maddry ,  Robert C. Reynolds ,  Abhijit Roychowdhury ,  Anita T. Fowler ,  John A. Secrist, III ,  Joseph A. Kozlowski ,  Bandarpalle B. Shankar ,  Ling Tong ,  Seong Heon Kim ,  Malcolm MacCoss ,  Srikanth Venkatraman ,  Vishal Verma

IPC分类号： A01N43/04 ,  A61K31/70 ,  A61K48/00 ,  A01N37/18 ,  A61K38/00 ,  A61P1/16 ,  A61K51/00 ,  A61M36/14 ,  A61K31/506 ,  A61K45/06 ,  C07D403/04 ,  C07D413/04 ,  C07D417/04 ,  C07D491/048 ,  C07D513/04 ,  C07D417/14

CPC分类号： A61K31/506 ,  A61K45/06 ,  C07D403/04 ,  C07D413/04 ,  C07D417/04 ,  C07D417/14 ,  C07D491/048 ,  C07D513/04

摘要： The present invention provides compounds of Formula (I): and tautomers, isomers, and esters of said compounds, and pharmaceutically acceptable salts, solvates, and prodrugs of said compounds, wherein each of R, R1, X, Y, Z, R2, R3, R4, R5, R6, R7, R8, R9, R18, R19 and n is selected independently and as defined herein. Compositions comprising such compounds are also provided. The compounds of the invention are effective as inhibitors of HCV, and are useful, alone and together with other therapeutic agents, in treating or preventing diseases or disorders such as viral infections and virus-related disorders.

公开(公告)号：US20130325058A1

公开(公告)日：2013-12-05

申请号：US13485388

申请日：2012-05-31

申请人： Wouter E. Roorda ,  Douglas H. Mehl ,  Rizza Garcia ,  Timothy C. Reynolds ,  Dinorah Merrill ,  Dawn Ma ,  David J. Milazzo ,  Aaron M. Fortson

发明人： Wouter E. Roorda ,  Douglas H. Mehl ,  Rizza Garcia ,  Timothy C. Reynolds ,  Dinorah Merrill ,  Dawn Ma ,  David J. Milazzo ,  Aaron M. Fortson

IPC分类号： A61B17/03

CPC分类号： A61B17/0469 ,  A61B17/0485 ,  A61B17/06061 ,  A61B2017/00637 ,  A61B2017/00663 ,  A61B2017/00778 ,  A61B2017/0472

摘要： A closure device for closing an opening in tissue is provided. The closure device includes an elongate member through which needles may be deployed. The closure device also includes a foot portion having one or more feet slidably mounted relative thereto. The feet are movable between a deployed position and a delivery position. The feet include cuffs removably mounted therein, with sutures connected between the cuffs. When the feet are in the deployed position and the needles are advanced, the needles securely engage the cuffs and draw the cuffs and suture through the lumen wall so that the opening in the lumen wall can be closed with the sutures.

摘要翻译： 提供了用于封闭组织中的开口的闭合装置。 闭合装置包括细长构件，针可通过细长构件展开。 闭合装置还包括具有相对于其可滑动地安装的一个或多个脚的脚部。 脚可在展开位置和放置位置之间移动。 脚部包括可拆卸地安装在其中的袖口，缝合线连接在袖口之间。 当脚处于展开位置并且针被推进时，针牢固地接合袖口并且拉出袖口并缝合穿过管腔壁，使得可以用缝合线封闭管腔壁中的开口。

公开(公告)号：USD688139S1

公开(公告)日：2013-08-20

申请号：US29432094

申请日：2012-09-13

申请人： Robert G. Larkin ,  Joanna C. Reynolds ,  Aaron F. Fitchko

设计人： Robert G. Larkin ,  Joanna C. Reynolds ,  Aaron F. Fitchko

公开(公告)号：US08470834B2

公开(公告)日：2013-06-25

申请号：US13059197

申请日：2009-08-19

申请人： Cecil D. Kwong ,  F. George Njoroge ,  Subramaniam Ananthan ,  Feng Geng ,  Hollis S. Kezar, III ,  Joseph A. Maddry ,  John J. Piwinski ,  Robert C. Reynolds ,  John A. Secrist, III ,  Neng-Yang Shih

发明人： Cecil D. Kwong ,  F. George Njoroge ,  Subramaniam Ananthan ,  Feng Geng ,  Hollis S. Kezar, III ,  Joseph A. Maddry ,  John J. Piwinski ,  Robert C. Reynolds ,  John A. Secrist, III ,  Neng-Yang Shih

IPC分类号： C07D239/50 ,  C07D213/72 ,  C07D405/02 ,  A61K31/505 ,  A61K31/443 ,  A61K31/497

CPC分类号： C07D239/50

摘要： The present invention provides compounds of Formula (I): (Chemical formula should be inserted here as it appears on abstract in paper form) (I) and tautomers, isomers, and esters of said compounds, and pharmaceutically acceptable salts, solvates, and prodrugs of said compounds, wherein each of R, R1, X, Y, Z, R2, R3, R4, R5, R6, R7, R8, R9, R18, R19, and n is selected independently and as defined herein. Compositions comprising such compounds are also provided. The compounds of the invention are effective as inhibitors of HCV, and are useful, alone and together with other therapeutic agents, in treating or preventing diseases or disorders such as viral infections and virus-related disorders.

摘要翻译： 本发明提供了式（I）化合物：（化学式应该插在这里，它以纸的形式出现）（I）和所述化合物的互变异构体，异构体和酯以及药学上可接受的盐，溶剂合物和前药 的所述化合物，其中R，R 1，X，Y，Z，R 2，R 3，R 4，R 5，R 6，R 7，R 8，R 9，R 18，R 19和n各自独立地并如本文所定义。 还提供了包含这些化合物的组合物。 本发明的化合物作为HCV的抑制剂是有效的，并且单独和与其它治疗剂一起用于治疗或预防疾病或病症如病毒感染和病毒相关疾病。

公开(公告)号：US20130006274A1

公开(公告)日：2013-01-03

申请号：US13615547

申请日：2012-09-13

申请人： Erik K. Walberg ,  Timothy C. Reynolds ,  Brian A. Ellingwood ,  Kai Y. Jair ,  Anthony Pantages

发明人： Erik K. Walberg ,  Timothy C. Reynolds ,  Brian A. Ellingwood ,  Kai Y. Jair ,  Anthony Pantages

IPC分类号： A61B17/10

CPC分类号： A61B17/10 ,  A61B17/0057 ,  A61B17/064 ,  A61B17/0644 ,  A61B17/068 ,  A61B17/083 ,  A61B17/1227 ,  A61B2017/00424 ,  A61B2017/00672

摘要： An apparatus for placement into an opening formed in a wall of a body lumen to deploy a closure element. The apparatus comprising a housing having a handle portion formed at a distal end, the handle portion configured to be engaged by a user when advancing the housing to deploy the closure element. A locator assembly and a carrier assembly are at least partially received in the housing. The locator assembly can have one or more expansion members that can selectably contact the wall of the body lumen and a proximal end configured to cooperate with a portion of a locator control system operable to expand the one or more expansion members. A triggering system cooperates with the locator assembly and is moveable toward the one or more expansion members of the locator assembly upon the locator control system being operated to expand the one or more expansion members.

公开(公告)号：US20110318305A1

公开(公告)日：2011-12-29

申请号：US13059193

申请日：2009-08-19

申请人： Ashok Arasappan ,  F. George Njoroge ,  Cecil D. Kwong ,  Subramaniam Ananthan ,  Frank Bennett ,  Jeremy Clark ,  Hollis S. Kezar, III ,  Vinay M. Girijavallabhan ,  Yuhua Huang ,  Regina Huelgas ,  Joseph A. Maddry ,  John J. Piwinski ,  Robert C. Reynolds ,  Abhijit Roychowdhury ,  Anita T. Fowler ,  Feng Geng ,  John A. Secrist, III ,  Neng-Yang Shih ,  Vishal Verma ,  Francisco Velazquez ,  Srikanth Venkatraman

发明人： Ashok Arasappan ,  F. George Njoroge ,  Cecil D. Kwong ,  Subramaniam Ananthan ,  Frank Bennett ,  Jeremy Clark ,  Hollis S. Kezar, III ,  Vinay M. Girijavallabhan ,  Yuhua Huang ,  Regina Huelgas ,  Joseph A. Maddry ,  John J. Piwinski ,  Robert C. Reynolds ,  Abhijit Roychowdhury ,  Anita T. Fowler ,  Feng Geng ,  John A. Secrist, III ,  Neng-Yang Shih ,  Vishal Verma ,  Francisco Velazquez ,  Srikanth Venkatraman

IPC分类号： A61K31/506 ,  C07D413/14 ,  A61P31/12 ,  A61K38/21 ,  A61K39/00 ,  A61K39/42 ,  C07D407/14 ,  A61K31/5377

CPC分类号： C07D239/48 ,  C07D401/04 ,  C07D401/14 ,  C07D403/04 ,  C07D405/04 ,  C07D409/04 ,  C07D413/04 ,  C07D413/14 ,  C07D417/04 ,  C07D417/14 ,  C07D491/04

摘要： The present invention provides compounds of Formula (I): and tautomers, isomers, and esters of said compounds, and pharmaceutically acceptable salts, solvates, and prodrugs of said compounds, wherein each of R, R1, X, Y, Z, R2, R3, R4, R5, R6, R7, R8, R9, R18, R19 and n is selected independently and as defined herein. Compositions comprising such compounds are also provided. The compounds of the invention are effective as inhibitors of HCV, and are useful, alone and together with other therapeutic agents, in treating or preventing diseases or disorders such as viral infections and virus-related disorders.

摘要翻译： 本发明提供式（I）的化合物：所述化合物的互变异构体，异构体和酯，以及所述化合物的药学上可接受的盐，溶剂合物和前药，其中R，R 1，X，Y，Z，R 2， R3，R4，R5，R6，R7，R8，R9，R18，R19和n独立选择和如本文所定义。 还提供了包含这些化合物的组合物。 本发明的化合物作为HCV的抑制剂是有效的，并且单独和与其它治疗剂一起用于治疗或预防疾病或病症如病毒感染和病毒相关疾病。

公开(公告)号：US20110213670A1

公开(公告)日：2011-09-01

申请号：US13018225

申请日：2011-01-31

申请人： Michael J. Strutton ,  Paulo Delgado ,  Slain J. Wilde ,  Chad Estes ,  Benjamin Turner ,  John Schult ,  John Maxwell ,  Jason C. Reynolds ,  Bryan S. Pocius ,  Horace Williams, II ,  John B. Nolt

发明人： Michael J. Strutton ,  Paulo Delgado ,  Slain J. Wilde ,  Chad Estes ,  Benjamin Turner ,  John Schult ,  John Maxwell ,  Jason C. Reynolds ,  Bryan S. Pocius ,  Horace Williams, II ,  John B. Nolt

IPC分类号： G06Q30/00 ,  G06F15/16

CPC分类号： G06Q30/02 ,  G06Q30/0241 ,  G06Q30/0277 ,  H04L51/066

摘要： Systems and methods for delivering application media content to multiple social media systems (SMSs) for display to SMS members. The method includes the steps of providing initial application media content to respective SMSs. Once a respective SMS member interacts with the initial content, a social relationship management system (SRMS) receives indication from an SMS of such interaction, and retrieves a unique application media file relating to application media content. The unique application media file is then applied to an application media container file that overcomes certain formatting protocols and requirements of the SMS and enables transmission and delivery of the application media content to the SMS. The application media content is then delivered to the SMS member on the SMS through the application media container file.

摘要翻译： 将应用媒体内容传送到多个社交媒体系统（SMS）以显示给SMS成员的系统和方法。 该方法包括向各个SMS提供初始应用媒体内容的步骤。 一旦相应的SMS成员与初始内容进行交互，则社会关系管理系统（SRMS）从SMS接收这种交互的指示，并检索与应用媒体内容有关的唯一的应用媒体文件。 然后将唯一的应用媒体文件应用于克服SMS的某些格式化协议和要求的应用媒体容器文件，并使应用媒体内容能够传送和传送到SMS。 然后通过应用媒体容器文件将应用媒体内容传送到SMS上的SMS成员。

公开(公告)号：US20110066164A1

公开(公告)日：2011-03-17

申请号：US12950628

申请日：2010-11-19

申请人： Erik K. Walberg ,  Timothy C. Reynolds ,  Anthony J. Pantages

发明人： Erik K. Walberg ,  Timothy C. Reynolds ,  Anthony J. Pantages

IPC分类号： A61B17/10

CPC分类号： A61B17/068 ,  A61B17/0057 ,  A61B90/92 ,  A61B2017/0042 ,  A61B2017/00429 ,  A61B2017/00455 ,  A61B2017/00668 ,  A61B2017/00986 ,  A61B2017/2925 ,  A61B2017/3484

摘要： An apparatus for placement into an opening formed in a wall of a body lumen to deploy a closure element. The apparatus comprising a housing having a handle portion formed at a distal end, the handle portion configured to be engaged by a user when advancing the housing to deploy the closure element. A triggering element deploys the closure device and can at least be partially formed in the housing. A throw reducing mechanism can slide relative to the housing and reduce the distance a user must stretch a hand to move a triggering system within the housing. The housing can include, or be connected to, a handle member having one or more expansion members which expand to provide a stable base for manipulating the apparatus.

摘要翻译： 一种用于放置在形成在体腔的壁中的开口中以展开闭合元件的装置。 所述装置包括具有形成在远端处的手柄部分的壳体，所述手柄部分构造成在推进所述壳体以展开所述封闭元件时由使用者接合。 触发元件展开闭合装置并且至少可部分地形成在壳体中。 抛掷减小机构可以相对于壳体滑动并且减小用户必须拉伸手以使壳体内的触发系统移动的距离。 壳体可以包括或连接到具有一个或多个膨胀构件的手柄构件，该膨胀构件膨胀以提供用于操纵装置的稳定基座。