公开(公告)号：US09041932B2

公开(公告)日：2015-05-26

申请号：US13734024

申请日：2013-01-04

Applicant: CHEMIMAGE TECHNOLOGIES LLC

Inventor： Ryan J. Priore ,  Thomas C. Voigt ,  Maxxwell A. R. Chatsko ,  Patrick J. Treado

IPC: G01N21/00 ,  G01J3/51 ,  G01J3/457 ,  G01N21/35 ,  G01J3/02 ,  G01N21/25 ,  G01J3/12 ,  G01N21/33 ,  G01N21/359 ,  G01N21/65 ,  G01N21/71 ,  G01N21/64

CPC classification number: G01J3/51 ,  G01J3/0224 ,  G01J3/457 ,  G01J2003/1213 ,  G01N21/255 ,  G01N21/33 ,  G01N21/35 ,  G01N21/359 ,  G01N21/65 ,  G01N21/718 ,  G01N2021/6471 ,  G01N2201/067 ,  G01N2201/129

Abstract: A system and method for detecting analytes using a conformal filter. A conformal filter, which may comprise a tunable filter, is configured to filter interacted photons conforming to a spectral shape correlated with an analyte of interest. Conformal filter configurations may be selected by consulting a modified look-up table associated with an analyte. An iterative methodology may be used to calibrate a conformal design for an analyte of interest, refine a previous conformal filter design for an analyte of interest, and/or generate a new conformal filter design for an analyte of interest.

Abstract translation: 一种使用保形过滤器检测分析物的系统和方法。 可以包括可调滤波器的保形滤波器被配置为滤波符合与感兴趣的分析物相关的光谱形状的相互作用的光子。 可以通过咨询与分析物相关联的经修改的查找表来选择保形过滤器配置。 可以使用迭代方法来校准感兴趣分析物的共形设计，改进目标分析物的先前共形过滤器设计，和/或为感兴趣的分析物生成新的保形过滤器设计。

公开(公告)号：US09157800B2

公开(公告)日：2015-10-13

申请号：US14155883

申请日：2014-01-15

Applicant: ChemImage Technologies LLC

Inventor： Ryan Priore ,  Patrick Treado ,  Matthew Nelson

IPC: G01J4/00 ,  G01J3/32 ,  G01J3/36 ,  G01J3/457 ,  G01J3/02 ,  G01J3/12 ,  G01N21/31

CPC classification number: G01J3/32 ,  G01J3/0224 ,  G01J3/36 ,  G01J3/457 ,  G01J2003/1213 ,  G01N21/31

Abstract: A system and method for detecting at least one target of interest using at least two conformal filters in a dual polarization configuration. A plurality of interacted photons are collected from a sample comprising at least one analyte of interest. The plurality of interacted photons are separated into at least a first and second optical component. The first optical component is passed through a first conformal filter and the second optical component is passed through a second conformal filter. A Data set corresponding to each filtered optical component is generated and an optical computation is applied to assess at least one characteristic of the analyte.

Abstract translation: 一种用于在双极化配置中使用至少两个共形滤波器来检测至少一个感兴趣的目标的系统和方法。 从包含至少一种目的分析物的样品收集多个相互作用的光子。 多个相互作用的光子被分成至少第一和第二光学部件。 第一光学部件通过第一保形过滤器，并且第二光学部件通过第二适形过滤器。 生成对应于每个滤波的光学部件的数据集，并应用光学计算来评估分析物的至少一个特性。

公开(公告)号：US12059253B2

公开(公告)日：2024-08-13

申请号：US17322368

申请日：2021-05-17

Applicant: CHEMIMAGE TECHNOLOGIES LLC

Inventor： Shona Stewart ,  Serena Augustine ,  Jeffrey Cohen ,  Ryan Priore

IPC: A61B5/1459 ,  A61B5/00 ,  A61B5/1473 ,  A61B17/00 ,  A61B34/30 ,  G01J3/02 ,  G01N21/25 ,  H03K19/173

CPC classification number: A61B5/1459 ,  A61B5/1473 ,  A61B5/4519 ,  A61B17/00234 ,  A61B34/30 ,  G01N21/255 ,  H03K19/1735 ,  A61B2034/302 ,  G01J3/0224 ,  G01N2201/06113

Abstract: Devices, systems, and methods for distinguishing tissue types are described herein. Such devices and systems may use dual polarization, conformal filters to acquire image data from target tissues and a processor to create an image in which the contrast between tissues has been enhanced.

公开(公告)号：US09329086B2

公开(公告)日：2016-05-03

申请号：US13905817

申请日：2013-05-30

Applicant: CHEMIMAGE TECHNOLOGIES LLC

Inventor： Patrick J. Treado ,  Ryan Priore

IPC: G01N21/00 ,  G01J3/51 ,  G01J3/457 ,  G01N21/25 ,  G01J3/02 ,  G01N21/33 ,  G01N21/359 ,  G01N21/65 ,  G01N21/71 ,  G01J3/12 ,  G01N21/64 ,  G01N21/35

CPC classification number: G01J3/51 ,  G01J3/0224 ,  G01J3/0272 ,  G01J3/457 ,  G01J2003/1213 ,  G01N21/255 ,  G01N21/33 ,  G01N21/35 ,  G01N21/359 ,  G01N21/65 ,  G01N21/718 ,  G01N2021/6471 ,  G01N2201/0221 ,  G01N2201/067 ,  G01N2201/129

Abstract: A portable system and method for analyzing biological tissue samples and detecting analytes associated with tissue oxygenation using a conformal filter. A conformal filter, which may comprise a tunable filter, is configured to filter interacted photons conforming to a spectral shape correlated with an analyte of interest. Conformal filter configurations may be selected by consulting a modified look-up table associated with an analyte. An iterative methodology may be used to calibrate a conformal design for an analyte of interest, refine a previous conformal filter design for an analyte of interest, and/or generate a new conformal filter design for an analyte of interest.

Abstract translation: 用于分析生物组织样品并使用保形过滤器检测与组织氧合相关的分析物的便携式系统和方法。 可以包括可调滤波器的保形滤波器被配置为滤波符合与感兴趣的分析物相关的光谱形状的相互作用的光子。 可以通过咨询与分析物相关联的经修改的查找表来选择保形过滤器配置。 可以使用迭代方法来校准感兴趣分析物的共形设计，改进目标分析物的先前共形过滤器设计，和/或为感兴趣的分析物生成新的保形过滤器设计。

公开(公告)号：US20210267499A1

公开(公告)日：2021-09-02

申请号：US17322368

申请日：2021-05-17

Applicant: CHEMIMAGE TECHNOLOGIES LLC

Inventor： Shona STEWART ,  Serena AUGUSTINE ,  Jeffrey COHEN ,  Ryan PRIORE

IPC: A61B5/1459 ,  H03K19/173 ,  A61B34/30 ,  A61B5/1473 ,  A61B17/00 ,  G01N21/25 ,  A61B5/00

Abstract: Devices, systems, and methods for distinguishing tissue types are described herein. Such devices and systems may use dual polarization, conformal filters to acquire image data from target tissues and a processor to create an image in which the contrast between tissues has been enhanced.

公开(公告)号：US11006868B2

公开(公告)日：2021-05-18

申请号：US15813766

申请日：2017-11-15

Applicant: CHEMIMAGE TECHNOLOGIES LLC

Inventor： Shona Stewart ,  Serena Augustine ,  Jeffrey Cohen ,  Ryan Priore

IPC: A61B5/1459 ,  H03K19/173 ,  A61B34/30 ,  A61B5/1473 ,  A61B17/00 ,  G01N21/25 ,  A61B5/00 ,  G01J3/02

Abstract: Devices, systems, and methods for distinguishing tissue types are described herein. Such devices and systems may use dual polarization, conformal filters to acquire image data from target tissues and a processor to create an image in which the contrast between tissues has been enhanced.

公开(公告)号：US20180199863A1

公开(公告)日：2018-07-19

申请号：US15813766

申请日：2017-11-15

Applicant: CHEMIMAGE TECHNOLOGIES LLC

Inventor： Shona STEWART ,  Serena AUGUSTINE ,  Jeffrey COHEN ,  Ryan PRIORE

IPC: A61B5/1459 ,  H03K19/173 ,  A61B5/1473 ,  G01N21/25 ,  A61B34/30 ,  A61B17/00 ,  G01J3/02

CPC classification number: A61B5/1459 ,  A61B5/1473 ,  A61B5/4519 ,  A61B17/00234 ,  A61B34/30 ,  A61B2034/302 ,  G01J3/0224 ,  G01N21/255 ,  G01N2201/06113 ,  H03K19/1735

Abstract: Devices, systems, and methods for distinguishing tissue types are described herein. Such devices and systems may use dual polarization, conformal filters to acquire image data from target tissues and a processor to create an image in which the contrast between tissues has been enhanced.

公开(公告)号：US09844334B2

公开(公告)日：2017-12-19

申请号：US14302225

申请日：2014-06-11

Applicant: CHEMIMAGE TECHNOLOGIES LLC

Inventor： Shona Stewart ,  Serena Augustine ,  Jeffrey Cohen ,  Ryan Priore

IPC: A61B6/00 ,  A61B5/00 ,  H03K19/173 ,  A61B5/1473 ,  A61B17/00 ,  G01N21/25 ,  G01J3/02 ,  A61B34/30

CPC classification number: A61B5/1459 ,  A61B5/1473 ,  A61B5/4519 ,  A61B17/00234 ,  A61B34/30 ,  A61B2034/302 ,  G01J3/0224 ,  G01N21/255 ,  G01N2201/06113 ,  H03K19/1735

Abstract: Devices, systems, and methods for distinguishing tissue types are described herein. Such devices and systems may use dual polarization, conformal filters to acquire image data from target tissues and a processor to create an image in which the contrast between tissues has been enhanced.