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42 条记录 (耗时 0.023 秒)

    Articulated catheter
    1.
    发明授权
    Articulated catheter 有权
    铰接导管

    公开(公告)号：US08529504B2

    公开(公告)日：2013-09-10

    申请号：US13185488

    申请日：2011-07-18

    申请人： Charles A. Gibson ,  Gary O'Boyle ,  Gary S. Falwell

    发明人： Charles A. Gibson ,  Gary O'Boyle ,  Gary S. Falwell

    IPC分类号： A61M31/00 ,  A61M37/00 ,  A61M25/00

    CPC分类号： A61M25/0147 ,  A61M25/0041 ,  A61M25/0054 ,  A61M25/0108 ,  A61M25/0141 ,  A61M25/0144 ,  A61M2025/0161

    摘要： Methods and apparatuses for manipulating an elongated flexible shaft of a catheter provide ease and reliability of positioning electrodes against or near tissue. Dual-bend flexible distal tips may be used in combination with flat wires. In some embodiments, flat wires which are free to rotate upon initial bending of shaft segments are employed. In some embodiments, one or more transition segments are used to relocate the satellite lumen-to-main lumen transition of pull wires away from a change in shaft stiffness.

    摘要翻译： 用于操纵导管的细长柔性轴的方法和装置提供了将电极定位在组织附近或附近的便利性和可靠性。 双弯曲柔性远端可与扁平线组合使用。 在一些实施例中，采用在轴段的初始弯曲时自由旋转的扁平线。 在一些实施例中，使用一个或多个过渡段来重新定位拉线的卫星管腔到主腔的转变远离轴刚度的变化。

    ARTICULATED CATHETER
    3.
    发明申请
    ARTICULATED CATHETER 有权

    公开(公告)号：US20110270173A1

    公开(公告)日：2011-11-03

    申请号：US13185488

    申请日：2011-07-18

    申请人： Charles A. Gibson ,  Gary O'Boyle ,  Gary S. Falwell

    发明人： Charles A. Gibson ,  Gary O'Boyle ,  Gary S. Falwell

    IPC分类号： A61M25/092

    CPC分类号： A61M25/0147 ,  A61M25/0041 ,  A61M25/0054 ,  A61M25/0108 ,  A61M25/0141 ,  A61M25/0144 ,  A61M2025/0161

    摘要： Methods and apparatuses for manipulating an elongated flexible shaft of a catheter provide ease and reliability of positioning electrodes against or near tissue. Dual-bend flexible distal tips may be used in combination with flat wires. In some embodiments, flat wires which are free to rotate upon initial bending of shaft segments are employed. In some embodiments, one or more transition segments are used to relocate the satellite lumen-to-main lumen transition of pull wires away from a change in shaft stiffness.

    摘要翻译： 用于操纵导管的细长柔性轴的方法和装置提供了将电极定位在组织附近或附近的便利性和可靠性。 双弯曲柔性远端可与扁平线组合使用。 在一些实施例中，采用在轴段的初始弯曲时自由旋转的扁平线。 在一些实施例中，使用一个或多个过渡段来重新定位拉线的卫星管腔到主腔的转变远离轴刚度的变化。

    Intracardiac grasp catheter
    4.
    发明授权
    Intracardiac grasp catheter 有权

    公开(公告)号：US06638278B2

    公开(公告)日：2003-10-28

    申请号：US10041243

    申请日：2002-01-08

    申请人： Gary S. Falwell ,  Charles A. Gibson, III

    发明人： Gary S. Falwell ,  Charles A. Gibson, III

    IPC分类号： A61B1814

    CPC分类号： A61B18/1492 ,  A61B18/1815 ,  A61B2018/00369

    摘要： A method of treating cardiac arrhythmia, including guiding a distal end portion of a catheter, the distal end portion having a distal tip and accommodating at least one elongated ablation electrode into a desired intracardiac region, for example, from the inferior vena cava into the right atrium of a human heart, and then from the right atrium into the right ventricle of the heart, pulling the catheter backwards, for example, towards the inferior vena cava, until the distal tip engages a edge of an intracardiac orifice, for example, the tricuspid annulus whereby the at least one ablation electrode engages a target tissue, for example, the isthmus of tissue between the tricuspid annulus and the inferior vena cava, deflecting the distal tip into a hook-shaped configuration, and activating the at least one ablation electrode to produce a substantially continuous lesion on the target tissue.

    Steerable electrode catheter
    5.
    发明授权
    Steerable electrode catheter 失效
    可导电电极导管

    公开(公告)号：US5611777A

    公开(公告)日：1997-03-18

    申请号：US518521

    申请日：1995-08-23

    申请人： Russell W. Bowden ,  Gary S. Falwell ,  Charles A. Gibson ,  Richard B. Stevens ,  Debbie E. Stevens-Wright

    发明人： Russell W. Bowden ,  Gary S. Falwell ,  Charles A. Gibson ,  Richard B. Stevens ,  Debbie E. Stevens-Wright

    IPC分类号： A61B5/0402 ,  A61M25/01 ,  A61M25/092 ,  A61M37/00 ,  A61B5/042 ,  A61M25/00

    CPC分类号： A61M25/0144 ,  A61M25/0136 ,  A61M25/0147 ,  A61B18/1815 ,  A61B2017/003 ,  A61B2018/0016 ,  A61B2018/00916 ,  A61B2018/00946 ,  A61B2018/00952 ,  A61M25/0141

    摘要： A steerable catheter includes control handle having a generally tubular housing with a longitudinal slot therein in which an axially or longitudinally movable two-part slideblock resides, and a generally cylindrical, rotatably mounted thumbwheel surrounding a distal portion of the tubular housing, for controlling the axial translation of the slideblock. The pullwire passes into the distal end of the control handle and is only secured to the proximal part of the two-part slideblock so as to prevent the user from placing the pullwire under compression. A tip radius adjusting wire is attached to and extends distally from a slide actuator in the control handle into and through the main catheter shaft portion. The free distal end of the tip radius adjusting wire is selectably Iocatable at different positions. The radius of curvature of the tip portion, when deflected, depends upon how far distally into the deflectable tip portion the radius adjusting wire has been advanced by the user. The electrode catheter thus has a deflectable tip whose radius of curvature is adjustable over a relatively wide range.

    摘要翻译： 可导向的导管包括控制手柄，其具有大致管状的壳体，其中纵向狭槽在其中，轴向或纵向可移动的两部分滑块位于其中，以及围绕管状壳体的远端部分的大致圆柱形可旋转地安装的指轮，用于控制轴向 幻灯片的翻译。 拉线进入控制手柄的远端，并且仅固定到两部分滑块的近端部分，以防止使用者将拉线放置在压缩状态。 尖端半径调节线附接到控制手柄中的滑块致动器并远离其延伸并且穿过主导管轴部分。 尖端半径调整线的自由端可选地位于不同的位置。 尖端部分的弯曲半径在偏转时取决于使用者已经使半径调节线前进到可偏转尖端部分的远端。 因此，电极导管具有可偏转的尖端，其弯曲半径在相对宽的范围内是可调节的。

    Process for the manufacture of diethylenetriamine
    6.
    发明授权
    Process for the manufacture of diethylenetriamine 失效
    二亚乙基三胺制备方法

    公开(公告)号：US5202491A

    公开(公告)日：1993-04-13

    申请号：US528554

    申请日：1990-05-25

    申请人： Lloyd M. Burgess ,  Charles A. Gibson ,  David J. Schreck

    发明人： Lloyd M. Burgess ,  Charles A. Gibson ,  David J. Schreck

    IPC分类号： C07C209/16 ,  C07C213/02

    CPC分类号： C07C209/16 ,  C07C213/02

    摘要： A continuously generated alkyleneamines producers composition comprising, based on 100% of the moles of the composition and exclusive of any MEA and water present,a) about 20 to about 40 mole % DETA,b) about 15 to about 60 mole % EDA (net generated),c) about 5 to about 18 mole % AEEA,d) about 3 to about 25 mole % of the combination of PIP, AEP and HEP,e) less than about 1 to about 5 mole % of one or more of TETAs and TEPAs,f) less than about 1 mole % of other polyalkylene polyamines,g) a DETA to AEEA mole ratio greater than about 1.35, andh) an EDA to DETA mole ratio less than 2.60,and the process of manufacturing it which comprises feeding hydrogen, ammonia, MEA and EDA, preferably provided from a recycle stream, to a reaction zone containing a fixed bed of a reductive amination catalyst in a tubular reactor, wherein the hydrogen comprises about 1 to about 30 mole percent of the feed in the reaction zone, the mole ratio of EDA to MEA is greater than 0.25 and the mole ratio of ammonia to MEA is about 1 to about 15, the temperature of the reaction zone is about 120.degree. C. to about 300.degree. C., the pressure of the reaction zone is about 1800 to about 2500 psig., the conversion of MEA is about 20 to about 60 weight percent, and recovering said producers composition from the reaction zone.

    摘要翻译： 连续生成的亚烷基胺生产者组合物，其包含基于组合物的摩尔数的100％，不包含存在的任何MEA和水，a）约20至约40摩尔％的DETA，b）约15至约60摩尔％的EDA（净 产生），c）约5至约18摩尔％的AEEA，d）PIP，AEP和HEP的组合的约3至约25摩尔％，e）小于约1至约5摩尔％的一种或多种TETA 和tEPA，f）小于约1摩尔％的其它多亚烷基多胺，g）DETA与AEEA摩尔比大于约1.35，和h）EDA与DETA摩尔比小于2.60，其制备方法包括 将优选从再循环流提供的氢气，氨，MEA和EDA进料到管式反应器中含有还原胺化催化剂固定床的反应区，其中氢包括约1至约30摩尔％ 反应区，EDA与MEA的摩尔比大于0.25，摩尔比为 氨至MEA为约1至约15，反应区的温度为约120℃至约300℃，反应区的压力为约1800至约2500psig，MEA的转化率为约 20至约60重量％，并从反应区回收所述生产者组合物。

    Process for thr manufacture of diethylenetriamine and aminoethylethanolamine
    7.
    发明授权
    Process for thr manufacture of diethylenetriamine and aminoethylethanolamine 失效
    二亚乙基三胺和氨基乙基乙醇胺的制备方法

    公开(公告)号：US5202490A

    公开(公告)日：1993-04-13

    申请号：US528555

    申请日：1990-05-25

    申请人： Lloyd M. Burgess ,  Charles A. Gibson ,  David J. Schreck

    发明人： Lloyd M. Burgess ,  Charles A. Gibson ,  David J. Schreck

    IPC分类号： C07C209/16 ,  C07C213/02

    CPC分类号： C07C209/16 ,  C07C213/02

    摘要： A continuously generated alkyleneamines producers composition comprising based on 100% of the moles of the compostion and exclusive of any MEA and water present,a) about 15 to about 35 mole % DETA,b) about 15 to about 55 mole % EDA (net generated),c) about 10 to about 35 mole % AEEA,d) about 3 to about 25 mole % of the combination of PIP, AEP and HEP,e) about 3 to about 10 mole % of one or more of TETAs and TEPAs,f) less than about 1 mole % of other polyalkylene polyamines, andg) a DETA to AEEA mole ratio greater than about 0.77 to less than 1.35,and the process of producing the same, which comprises feeding hydrogen, ammonia, MEA and EDA, preferably provided from a recycle stream, to a reaction zone containing a fixed bed of a reductive amination catalyst in a tubular reactor, wherein the hydrogen comprises about 10 to about 50 mole percent of the feed in the reaction zone, the mole ratio of EDA to MEA is less than about 0.25 and the mole ratio of ammonia to MEA is about 1 to about 10, the temperature of the reaction zone is about 120.degree. C. to about 300.degree. C., the pressure of the reaction zone is about 1000 to about 1800 psig, the conversion of MEA is about 20 to about 50 weight percent, and recovering said producers composition from the reaction zone.

    摘要翻译： 连续生成的亚烷基胺生产者组合物包含基于组合物的摩尔数的100％，不包含存在的任何MEA和水，a）约15至约35摩尔％DETA，b）约15至约55摩尔％EDA（净产生 ），c）约10至约35摩尔％的AEEA，d）PIP，AEP和HEP的组合约3至约25摩尔％，e）约3至约10摩尔％的一种或多种TETA和TEPAs， f）小于约1摩尔％的其它多亚烷基多胺，以及g）DETA与AEEA摩尔比大于约0.77至小于1.35，其制备方法包括进料氢气，氨气，MEA和EDA， 优选从再循环流提供到在管式反应器中含有还原胺化催化剂固定床的反应区，其中氢包含反应区中进料的约10至约50摩尔％，EDA与 MEA小于约0.25，氨与MEA的摩尔比为约1至约1 约10℃，反应区的温度为约120℃至约300℃，反应区的压力为约1000至约1800psig，MEA的转化率为约20至约50重量％，和 从反应区回收所述生产者组合物。

    Process for the treatment of organic amine compositions
    8.
    发明授权
    Process for the treatment of organic amine compositions 失效
    用于处理有机胺组合物的方法

    公开(公告)号：US4381223A

    公开(公告)日：1983-04-26

    申请号：US307223

    申请日：1981-09-30

    申请人： Charles A. Gibson ,  Moinuddin Ahmed ,  Michael Habenschuss

    发明人： Charles A. Gibson ,  Moinuddin Ahmed ,  Michael Habenschuss

    IPC分类号： C07C67/00 ,  C07C209/00 ,  C07C209/86 ,  C07C211/14 ,  C07C213/00 ,  C07C213/10 ,  C07C215/06 ,  C07C215/08 ,  C07C215/12 ,  B01D3/00

    CPC分类号： C07C215/08 ,  C07C213/10 ,  C07C215/12

    摘要： This invention provides for the separation of an amine composition undergoing processing at high temperatures and pressures which amine composition contains volatile components and less volatile components where the volatile components are desirable for further processing and/or utilization and the less volatile components are less desirable for further processing and/or utilization. The separation serves to divide the amine composition into two streams, one which is enriched in the volatile components and the other which is enriched in the less volatile components.

    摘要翻译： 本发明提供了在高温和高压下进行加工的胺组合物的分离，该胺组合物含有挥发性组分和较不易挥发的组分，其中挥发性组分对于进一步处理和/或利用是理想的，并且较不易挥发的组分对于进一步的 处理和/或利用。 该分离用于将胺组合物分成两股，其中富含挥发性组分的物质和富含较不易挥发组分的另一种。