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    Mapping and Ablation Method for the Treatment of Ventricular Tachycardia
    3.
    发明申请
    Mapping and Ablation Method for the Treatment of Ventricular Tachycardia 有权
    心室心动过速治疗的绘图和消融方法

    公开(公告)号：US20080281391A1

    公开(公告)日：2008-11-13

    申请号：US11597082

    申请日：2005-05-17

    申请人： David MacAdam ,  Ding Sheng He

    发明人： David MacAdam ,  Ding Sheng He

    IPC分类号： A61B18/12

    CPC分类号： A61B18/1492 ,  A61B5/042 ,  A61B2018/00214 ,  A61B2018/00839

    摘要： An apparatus for mapping and/or ablating tissue includes a braided conductive member that that may be inverted to provide a ring-shaped surface. When a distal tip of the braided conductive member is retracted within the braided conductive member, the lack of a protrusion allows the ring-shaped surface to contact a tissue wall such as a cardiac wall. In an alternative configuration, the braided conductive member may be configured with the distal portion forming a proboscis that can be used to stably position the braided conductive member relative to a blood vessel, such as a ventricular outflow tract. The braided conductive member has a plurality of electronically active sites that may be accessed individually for stable mapping over a broad area for stable mapping or ablation to form broad and deep lesions.

    摘要翻译： 用于映射和/或消融组织的装置包括可被倒置以提供环形表面的编织导电构件。 当编织导电构件的远侧末端缩回到编织导电构件内时，缺少突起允许环形表面接触诸如心脏壁的组织壁。 在替代配置中，编织导电构件可构造成具有形成长鼻的远端部分，其可用于相对于诸如心室流出道的血管来稳定地定位编织导电构件。 编织导电构件具有多个电子活性位点，其可以单独访问以在广泛区域上稳定映射以用于稳定的映射或消融以形成宽而深的损伤。

    BIOIMPEDANCE-ASSISTED PLACEMENT OF A MEDICAL DEVICE
    5.
    发明申请
    BIOIMPEDANCE-ASSISTED PLACEMENT OF A MEDICAL DEVICE 有权
    医疗设备的生物安全辅助放置

    公开(公告)号：US20120108950A1

    公开(公告)日：2012-05-03

    申请号：US13283395

    申请日：2011-10-27

    申请人： Ding Sheng He ,  David J. Ciavarella ,  Eddie K. Burnside

    发明人： Ding Sheng He ,  David J. Ciavarella ,  Eddie K. Burnside

    IPC分类号： A61B5/053 ,  A61B5/055 ,  A61B8/00 ,  A61M25/00

    CPC分类号： A61M25/0105 ,  A61B5/068 ,  A61B17/00234 ,  A61B34/20 ,  A61B2017/00026 ,  A61B2017/00331 ,  A61B2034/2051 ,  A61M25/01 ,  A61M2025/0166

    摘要： A system and method for guiding a catheter or other medical device to a desired target destination within the vasculature of a patient via bioimpedance measurements is disclosed. The target destination in one embodiment includes placement of the catheter such that a distal tip thereof is disposed proximate the heart, e.g., the junction of the right atrium and superior vena cava. In one embodiment the method for guiding the catheter comprises introducing the catheter into a vessel of the patient, the catheter defining a lumen through which fluids can be infused into the vasculature of the patient. The catheter is advanced toward a target destination within the vasculature. A first impedance value based on intravascular detection of at least one electrical property related to a first tissue surface of the vessel is calculated to enable determination of the proximity of a distal end of the catheter to the target destination.

    摘要翻译： 公开了一种用于通过生物阻抗测量将导管或其他医疗装置引导到患者脉管系统内的期望目的地目的地的系统和方法。 在一个实施例中的目标目的地包括导管的放置，使得其远侧末端设置在心脏附近，例如右心房和上腔静脉的连接处。 在一个实施例中，用于引导导管的方法包括将导管引入患者的容器中，该导管限定了内腔，流体可以通过内腔输注到患者的脉管系统中。 导管朝向脉管系统内的目标目标前进。 计算基于与血管的第一组织表面相关的至少一个电性质的血管内检测的第一阻抗值，以使得能够确定导管的远端与目的地的接近度。

    Mapping and ablation method for the treatment of ventricular tachycardia
    6.
    发明授权
    Mapping and ablation method for the treatment of ventricular tachycardia 有权
    用于治疗室性心动过速的映射和消融方法

    公开(公告)号：US08945116B2

    公开(公告)日：2015-02-03

    申请号：US11597082

    申请日：2005-05-17

    申请人： David MacAdam ,  Ding Sheng He

    发明人： David MacAdam ,  Ding Sheng He

    IPC分类号： A61B18/12 ,  A61B5/042 ,  A61B18/14 ,  A61B18/00

    CPC分类号： A61B18/1492 ,  A61B5/042 ,  A61B2018/00214 ,  A61B2018/00839

    摘要： An apparatus for mapping and/or ablating tissue includes a braided conductive member that may be inverted to provide a ring-shaped surface. When a distal tip of the braided conductive member is retracted within the braided conductive member, the lack of a protrusion allows the ring-shaped surface to contact a tissue wall such as a cardiac wall. In an alternative configuration, the braided conductive member may be configured with the distal portion forming a proboscis that can be used to stably position the braided conductive member relative to a blood vessel, such as a ventricular outflow tract. The braided conductive member has a plurality of electronically active sites that may be accessed individually for stable mapping over a broad area for stable mapping or ablation to form broad and deep lesions.

    摘要翻译： 用于映射和/或消融组织的装置包括编织导电构件，其可被倒置以提供环形表面。 当编织导电构件的远侧末端缩回到编织导电构件内时，缺少突起允许环形表面接触诸如心脏壁的组织壁。 在替代配置中，编织导电构件可构造成具有形成长鼻的远端部分，其可用于相对于诸如心室流出道的血管来稳定地定位编织导电构件。 编织导电构件具有多个电子活性位点，其可以单独访问以在广泛区域上稳定映射以用于稳定的映射或消融以形成宽而深的损伤。

    Bioimpedance-assisted placement of a medical device
    7.
    发明授权
    Bioimpedance-assisted placement of a medical device 有权
    生物阻抗辅助放置医疗器械

    公开(公告)号：US08801693B2

    公开(公告)日：2014-08-12

    申请号：US13283395

    申请日：2011-10-27

    申请人： Ding Sheng He ,  David J. Ciavarella ,  Eddie K. Burnside

    发明人： Ding Sheng He ,  David J. Ciavarella ,  Eddie K. Burnside

    IPC分类号： A61B5/053 ,  A61M25/095 ,  A61B5/055 ,  A61B8/00

    CPC分类号： A61M25/0105 ,  A61B5/068 ,  A61B17/00234 ,  A61B34/20 ,  A61B2017/00026 ,  A61B2017/00331 ,  A61B2034/2051 ,  A61M25/01 ,  A61M2025/0166

    摘要： A system and method for guiding a catheter or other medical device to a desired target destination within the vasculature of a patient via bioimpedance measurements is disclosed. The target destination in one embodiment includes placement of the catheter such that a distal tip thereof is disposed proximate the heart, e.g., the junction of the right atrium and superior vena cava. In one embodiment the method for guiding the catheter comprises introducing the catheter into a vessel of the patient, the catheter defining a lumen through which fluids can be infused into the vasculature of the patient. The catheter is advanced toward a target destination within the vasculature. A first impedance value based on intravascular detection of at least one electrical property related to a first tissue surface of the vessel is calculated to enable determination of the proximity of a distal end of the catheter to the target destination.

    摘要翻译： 公开了一种用于通过生物阻抗测量将导管或其他医疗装置引导到患者脉管系统内的期望目的地目的地的系统和方法。 在一个实施例中的目标目的地包括导管的放置，使得其远侧末端设置在心脏附近，例如右心房和上腔静脉的连接处。 在一个实施例中，用于引导导管的方法包括将导管引入患者的容器中，该导管限定了内腔，流体可以通过内腔输注到患者的脉管系统中。 导管朝向脉管系统内的目标目标前进。 计算基于与血管的第一组织表面相关的至少一个电性质的血管内检测的第一阻抗值，以使得能够确定导管的远端与目的地的接近度。

    Optimization method for cardiac resynchronization therapy
    9.
    发明申请
    Optimization method for cardiac resynchronization therapy 审中-公开
    心脏再同步治疗的优化方法

    公开(公告)号：US20060190045A1

    公开(公告)日：2006-08-24

    申请号：US10566152

    申请日：2004-07-28

    申请人： Frank Marcus ,  Ding Sheng He

    发明人： Frank Marcus ,  Ding Sheng He

    IPC分类号： A61N1/368

    CPC分类号： A61B5/1107 ,  A61B5/6869 ,  A61B5/7217 ,  A61N1/3627 ,  A61N1/36542 ,  A61N1/3682 ,  A61N1/3684

    摘要： The patterns of contraction and relaxation of the heart before and during left ventricular or biventricular pacing are analyzed and displayed in real time mode to assist physicians to screen patients for cardiac resynchronization therapy, to set the optimal AN or right ventricle to left ventricle interval delay, and to select the site(s) of pacing that result in optimal cardiac performance. The system includes an accelerometer sensor (40); a programmable pace maker (35, 41), a computer data analysis module (32), and may also include a 2D and 3D visual graphic display of analytic results (43, 44), i.e. a Ventricular Contraction Map. A feedback network (32) provides direction for optimal pacing leads placement. The method includes selecting a location to place the leads of a cardiac pacing device, collecting seismocardiographic (SCG) data corresponding to heart motion during paced beats of a patient's heart, determining hemodynamic and electrophysiological parameters based on the SCG data, repeating the preceding steps for another lead placement location, and selecting a lead placement location that provides the best cardiac performance by comparing the calculated hemodynamic and electrophysiological parameters for each different lead placement location.

    摘要翻译： 在实时模式下分析和显示左心室或双心室起搏前后心脏收缩和松弛的模式，以协助医师筛查患者心脏再同步治疗，将最佳AN或右心室设置为左心室间隔延迟， 并选择导致最佳心脏性能的起搏部位。 该系统包括加速度传感器（40）; 可编程起搏器（35,41），计算机数据分析模块（32），并且还可以包括分析结果（43,44）的2D和3D视觉图形显示，即心室收缩图。 反馈网络（32）提供了最佳起搏线放置的方向。 所述方法包括选择放置心脏起搏装置的引线的位置，在患者心脏的起搏节拍期间收集对应于心脏运动的心脏断层图（SCG）数据，基于SCG数据确定血流动力学和电生理参数，重复前述步骤 通过比较每个不同引线放置位置的计算血液动力学和电生理参数，选择提供最佳心脏性能的引导位置位置。