公开(公告)号：US20110071036A1

公开(公告)日：2011-03-24

申请号：US12993108

申请日：2009-05-18

申请人： Roel Penterman ,  Christopher James Backhouse

发明人： Roel Penterman ,  Christopher James Backhouse

IPC分类号： C40B30/00 ,  H01L21/00 ,  G01N35/10 ,  G01N27/447

CPC分类号： G01N27/44791 ,  G01N27/44795

摘要： The present invention relates to an isoelectric focusing biochip, in particular for fractionating, detecting and/or collecting analytes, such as proteins, metabolites, glycoproteins and/or peptides, a method for fractionating, detecting and/or collecting analytes, with such a biochip and a manufacturing method for such a biochip.

摘要翻译： 本发明涉及等电聚焦生物芯片，特别是用于分级，检测和/或收集分析物，例如蛋白质，代谢物，糖蛋白和/或肽，一种用这种生物芯片分级，检测和/或收集分析物的方法 以及这种生物芯片的制造方法。

公开(公告)号：US20100252124A1

公开(公告)日：2010-10-07

申请号：US12743838

申请日：2008-11-18

申请人： Ralph Kurt ,  Emiel Peeters ,  Roel Penterman ,  Martin Ouwerkerk ,  Christopher James Backhouse

发明人： Ralph Kurt ,  Emiel Peeters ,  Roel Penterman ,  Martin Ouwerkerk ,  Christopher James Backhouse

IPC分类号： F16K49/00

CPC分类号： F16K99/0001 ,  B01L3/502738 ,  B01L2200/146 ,  B01L2200/147 ,  B01L2300/0627 ,  B01L2300/1838 ,  B01L2400/0638 ,  B01L2400/0677 ,  F16K99/0026 ,  F16K99/0044 ,  F16K99/0061 ,  F16K2099/0084 ,  G01N2035/00247 ,  Y10T137/6606

摘要： The invention relates to a valve for opening and closing a channel (3) of a microfluidic system, respectively. According to the invention, the valve comprises an actuation medium (2) that undergoes a volume change with changing temperature; and a heater arrangement (5) for generating a temperature gradient in the actuation medium (2) with respect to the actuation medium's (2) distance relative to the channel (3); wherein due to an expansion or a contraction of the actuation medium (2) the channel (3) is closed or opened, respectively. When the heater arrangement (5) is activated in such a way that a higher temperature is generated in the actuation medium (2) which is nearer to the channel (3) and a lower temperature is generated in the actuation medium (2) which is further away from the channel (3) the valve can be closed and vice versa. Accordingly, such a valve for a microfluidic system is provided which can be reliably actuated during a long time of use.

摘要翻译： 本发明涉及分别用于打开和关闭微流体系统的通道（3）的阀。 根据本发明，该阀包括在变化温度下经历体积变化的致动介质（2）; 以及加热器装置（5），用于相对于所述致动介质（2）相对于所述通道（3）的距离产生所述致动介质（2）中的温度梯度; 其中由于致动介质（2）的膨胀或收缩，通道（3）分别关闭或打开。 当加热器装置（5）以这样一种方式启动时，使得在更靠近通道（3）的致动介质（2）中产生较高的温度，并且在致动介质（2）中产生较低的温度 更远离通道（3），阀可以关闭，反之亦然。 因此，提供了这种用于微流体系统的阀，其可以在长时间使用期间被可靠地致动。