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公开(公告)号：US5976816A
公开(公告)日：1999-11-02
申请号：US312202
申请日：1994-09-26
IPC分类号： G01N33/53 , C07K14/47 , C07K16/18 , C12N15/02 , C12P21/08 , C12R1/91 , G01N33/50 , G01N33/531 , G01N33/573 , G01N33/577 , G01N33/68 , G01N33/567 , C07K16/00
CPC分类号： G01N33/5091 , C07K14/4711 , C07K16/18 , G01N33/573 , G01N33/6872 , G01N33/6896 , G01N2333/9121 , G01N2800/2821
摘要： The present invention provides methods for the diagnosis of Alzheimer's disease using human cells. Specifically, one method detects differences between potassium channels in cells from Alzheimer's patient and normal donors, and differences in intracellular calcium concentrations between Alzheimer's and normal cells in response to chemicals known to increase intracellular calcium levels. Other methods detect differences between the memory associated GTP binding Cp20 protein levels between Alzheimer's and normal cells.
摘要翻译： 本发明提供了使用人类细胞诊断阿尔茨海默病的方法。 具体来说，一种方法检测来自阿尔茨海默病患者和正常供体的细胞中的钾通道之间的差异，以及响应于已知增加细胞内钙水平的化学物质的阿尔茨海默氏病和正常细胞之间的细胞内钙浓度的差异。 其他方法检测与老年痴呆和正常细胞之间记忆相关的GTP结合Cp20蛋白水平之间的差异。
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公开(公告)号：US06080582A
公开(公告)日：2000-06-27
申请号：US79347
申请日：1998-05-15
IPC分类号： G01N33/53 , C07K14/47 , C07K16/18 , C12N15/02 , C12P21/08 , C12R1/91 , G01N33/50 , G01N33/531 , G01N33/573 , G01N33/577 , G01N33/68 , A61K38/00 , C07K16/00
CPC分类号： G01N33/5091 , C07K14/4711 , C07K16/18 , G01N33/573 , G01N33/6872 , G01N33/6896 , G01N2333/9121 , G01N2800/2821
摘要： The present invention provides methods for the diagnosis of Alzheimer's disease using human cells. Specifically, one method detects differences between potassium channels in cells from Alzheimer's patient and normal donors, and differences in intracellular calcium concentrations between Alzheimer's and normal cells in response to chemicals known to increase intracellular calcium levels. Other methods detect differences between the memory associated GTP binding Cp20 protein levels between Alzheimer's and normal cells.
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公开(公告)号：US20090165307A1
公开(公告)日：2009-07-02
申请号：US12005560
申请日：2007-12-27
申请人： Cheong Yin Lam , Christopher S. Kim
发明人： Cheong Yin Lam , Christopher S. Kim
CPC分类号： A47G21/023 , A47G21/103
摘要： A pair of chopsticks comprising a first chopstick having a long narrow body, at least one tine on a first end, a second end opposite the first end, and a connection means disposed on the first chopstick body; a second chopstick having a long narrow body, at least one tine one a first end, a second end opposite the first end, and a connection means disposed on the second chopstick body; and wherein the at least one tine of the first chopstick is proximate the at least one tine of the second chopstick when the connection means of the first chopstick is releasably secured to the connection means of the second chopstick.
摘要翻译： 一种筷子，包括具有长的窄体的第一筷子，在第一端上至少有一个齿，与第一端相对的第二端，以及设置在第一筷子本体上的连接装置; 第二筷子，具有长的窄体，至少一个齿，第一端，与第一端相对的第二端，以及设置在第二筷体上的连接装置; 并且其中当所述第一筷子的所述连接装置可释放地固定到所述第二筷子的连接装置时，所述第一筷子的所述至少一个齿接近所述第二筷子的所述至少一个齿。
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