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公开(公告)号：US09700644B2
公开(公告)日：2017-07-11
申请号：US11880670
申请日：2007-07-24
申请人： Herbert J. Kaiser , Anchalee Thanavaro , Brandon W. Dell'Aringa , Bryan M. Tienes , Daniel A. Klein , George W. Wagner
发明人： Herbert J. Kaiser , Anchalee Thanavaro , Brandon W. Dell'Aringa , Bryan M. Tienes , Daniel A. Klein , George W. Wagner
IPC分类号： C11D7/18 , C11D3/02 , C07C409/00 , A62D3/00 , C11D3/48 , A61L2/18 , A01N59/00 , A62D3/38 , A62D101/02
CPC分类号： A61L2/186 , A01N59/00 , A62D3/38 , A62D2101/02 , A01N25/08 , A01N25/10 , A01N25/22 , A01N25/26 , A01N25/30 , A01N33/12 , A01N37/02 , A01N37/36 , A01N37/40 , A01N59/04 , A01N59/14 , A01N59/16 , A01N2300/00
摘要： A one part, solids containing decontamination blend composition comprises a solid acetyl donor coated with a compound that protects it from hydrolysis, a peroxygen source, optionally a catalyst, optionally a surfactant, and optionally a buffer. The decontamination blend composition is generally in a dry powder, particle, etc form or in a tablet, pill, etc form and is complete in and of itself in that no additional compounds are required prior to use and is readily distributed as a one package system. Upon the addition of water, a peroxygen compound such as hydrogen peroxide is formed, and peracetic acid is generated under alkaline conditions. The decontamination blend composition is particularly suitable for oxidizing various chemical and biological compounds thereby eradicating the same in situ as on surfaces, clothes, articles, and the like. Representative contaminants include mustard gas, nerve gas, bacterial toxins, anthrax, bird flu, and the like.
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公开(公告)号：US20100196503A1
公开(公告)日：2010-08-05
申请号：US12322702
申请日：2009-02-05
申请人： Christopher C. Heisig , Herbert J. Kaiser , Daniel A. Klein , Jessica S. Linder , Katie J. Frey , Nancy E. Kaiser , Jerry L. Newman
发明人： Christopher C. Heisig , Herbert J. Kaiser , Daniel A. Klein , Jessica S. Linder , Katie J. Frey , Nancy E. Kaiser , Jerry L. Newman
IPC分类号： A61K33/40
CPC分类号： A61K31/327 , A01N59/00 , A61K31/16 , A61K33/40 , C11D3/3917 , C11D3/3947 , C11D3/48 , A01N37/16 , A01N2300/00 , A61K2300/00
摘要： A low odor, liquid disinfectant composition comprising multiple components, which, upon mixing, provide an aqueous solution comprising low levels of peracetic acid for use in decontaminating articles and surfaces contaminated with bacteria, viruses, fungi and other biological contaminants such as spores, including, but not limited to, Clostridium difficile (C.diff). The disinfectant composition is prepared just prior to use by combining two or more separately packaged components.
摘要翻译： 一种低气味的液体消毒剂组合物，其包含多个组分，其在混合时提供包含低水平的过乙酸的水溶液，用于净化由细菌，病毒，真菌和其它生物污染物（例如孢子）污染的物品和表面， 但不限于艰难梭菌（C.diff）。 消毒剂组合物在使用之前通过组合两种或多种单独包装的组分来制备。
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公开(公告)号：US20080045593A1
公开(公告)日：2008-02-21
申请号：US11504172
申请日：2006-08-15
申请人： Herbert J. Kaiser , Anchalee Thanavaro , Brandon W. Dell'Aringa , Bryan M. Tienes , Daniel A. Klein , George W. Wagner
发明人： Herbert J. Kaiser , Anchalee Thanavaro , Brandon W. Dell'Aringa , Bryan M. Tienes , Daniel A. Klein , George W. Wagner
IPC分类号： A01N37/00
CPC分类号： A62D3/38 , A61L2/186 , A61L2/23 , A61L2202/24 , A62D2101/02
摘要： A one part, solids containing decontamination blend composition comprises a solid acetyl donor coated with a compound that protects it from hydrolysis, a peroxygen source, optionally a catalyst, optionally a surfactant, and optionally a buffer. The decontamination blend composition is generally in a dry powder, particle, etc. form or in a tablet, pill, etc. form and is complete in and of itself in that no additional compounds are required prior to use and is readily distributed as a one package system. Upon the addition of water, a peroxygen compound such as hydrogen peroxide is formed, and peracetic acid is generated under alkaline conditions. The decontamination blend composition is particularly suitable for oxidizing various chemical and biological compounds thereby eradicating the same in situ as on surfaces, clothes, articles, and the like. Representative contaminants include mustard gas, nerve gas, bacterial toxins, anthrax, bird flu, and the like.
摘要翻译： 一部分固体含有去污混合物组合物包括涂覆有保护其免于水解的化合物的固体乙酰基供体，过氧源，任选的催化剂，任选的表面活性剂和任选的缓冲剂。 去污混合物组合物通常为干粉，颗粒等形式或片剂，丸剂等形式，并且其自身完整且在使用之前不需要额外的化合物，并且易于以一种方式分布 包装系统 加入水后，形成过氧化氢等过氧化合物，在碱性条件下生成过乙酸。 去污混合物组合物特别适用于氧化各种化学和生物化合物，从而在表面，衣物，制品等上原位消除它们。 代表性的污染物包括芥子气，神经气体，细菌毒素，炭疽，禽流感等。
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公开(公告)号：US09724550B2
公开(公告)日：2017-08-08
申请号：US11504172
申请日：2006-08-15
申请人： Herbert J. Kaiser , Anchalee Thanavaro , Brandon W. Dell'Aringa , Bryan M. Tienes , Daniel A. Klein , George W. Wagner
发明人： Herbert J. Kaiser , Anchalee Thanavaro , Brandon W. Dell'Aringa , Bryan M. Tienes , Daniel A. Klein , George W. Wagner
IPC分类号： C11D7/18 , C11D3/02 , C07C409/00 , A62D3/00 , C11D3/48 , A62D3/38 , A61L2/18 , A61L2/23 , A62D101/02
CPC分类号： A62D3/38 , A61L2/186 , A61L2/23 , A61L2202/24 , A62D2101/02
摘要： A one part, solids containing decontamination blend composition comprises a solid acetyl donor coated with a compound that protects it from hydrolysis, a peroxygen source, optionally a catalyst, optionally a surfactant, and optionally a buffer. The decontamination blend composition is generally in a dry powder, particle, etc. form or in a tablet, pill, etc. form and is complete in and of itself in that no additional compounds are required prior to use and is readily distributed as a one package system. Upon the addition of water, a peroxygen compound such as hydrogen peroxide is formed, and peracetic acid is generated under alkaline conditions. The decontamination blend composition is particularly suitable for oxidizing various chemical and biological compounds thereby eradicating the same in situ as on surfaces, clothes, articles, and the like. Representative contaminants include mustard gas, nerve gas, bacterial toxins, anthrax, bird flu, and the like.
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公开(公告)号：US07268165B2
公开(公告)日：2007-09-11
申请号：US10922456
申请日：2004-08-20
摘要： Antimicrobial compositions which can be used wherever disinfecting compositions are needed, such as in a hospital, healthcare industry, workplace, recreational facility, home or similar environment. The antimicrobial compositions are particularly useful as a topical application for a substrate, such as skin and can be used as a hand sanitizer or pre-surgical scrub. The compositions comprise a synergistic combination of a simple aliphatic alcohol and an activity enhancing substance, wherein the composition provides, heretofore unexpected, persistent activity against a broad range of microorganisms, including gram-negative organisms, while moisturizing the skin.
摘要翻译： 可以在需要消毒组合物的地方使用的抗微生物组合物，例如在医院，医疗保健行业，工作场所，娱乐设施，家庭或类似环境中。 抗微生物组合物特别可用作底物如皮肤的局部应用，并且可以用作手部消毒剂或手术前擦洗。 组合物包含简单的脂肪醇和活性增强物质的协同组合，其中该组合物在保湿皮肤的同时，提供了针对广泛范围的微生物（包括革兰氏阴性生物体）的持续活性。
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公开(公告)号：US6060585A
公开(公告)日：2000-05-09
申请号：US34509
申请日：1998-03-04
申请人： Samuel H. Gellman , Daniel H. Appella , Laurie A. Christianson , Daniel A. Klein , Susanne Krauthauser , Yong Jun Chung , Xifang Wang
发明人： Samuel H. Gellman , Daniel H. Appella , Laurie A. Christianson , Daniel A. Klein , Susanne Krauthauser , Yong Jun Chung , Xifang Wang
IPC分类号： C07C237/24 , C07K5/023
CPC分类号： C07C237/24 , C07B2200/11 , C07C2101/14
摘要： Disclosed are .beta.-peptides containing cylcoalkyl, cycloalkenyl, and heterocylic substituents which encompass the .alpha. and .beta. carbons of the peptide backbone. The .beta.-peptides adopt stable helical and sheet structures in both the solid state and in solution. Method of generating combinatorial libraries of peptides containing .beta.-peptide residues and the libraries formed thereby are disclosed.
摘要翻译： 公开了含有环状烷基，环烯基和杂环取代基的β-肽，其包括肽主链的α和β碳。 β - 肽在固态和溶液中都采用稳定的螺旋和片状结构。 公开了产生含有β-肽残基的肽组合文库的方法和由此形成的文库。
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公开(公告)号：USD370379S
公开(公告)日：1996-06-04
申请号：US39529
申请日：1995-05-24
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公开(公告)号：US08518941B2
公开(公告)日：2013-08-27
申请号：US12806731
申请日：2010-08-19
摘要： An extreme temperature decontamination composition such as a solution for destroying microorganisms, chemical warfare and bioterrorism agents is utilized that generally does not freeze at low temperatures down to about minus 25° F. and also has no significant evaporation or decomposition at temperatures up to about 120° F. The solution is effective against nerve agents and vesicants such as VX and HD, and various biological agents. The composition comprises a metallic salt of dichloroisocyanuric acid or dibromoisocyanuric acid, an aqueous solvent system comprising polar compounds such as water and an alkyl glycol, and a quasi hydrophilic compound. The composition can be formulated as a one part system wherein all components are blended together.
摘要翻译： 使用极端温度去污组合物，例如用于破坏微生物的溶液，化学战和生物恐怖剂，其通常在低至约零下25摄氏度的低温下不会冷冻，并且在高达约120℃的温度下也没有明显的蒸发或分解 °F。该溶液对神经药物和Vesicants如VX和HD以及各种生物制剂有效。 该组合物包含二氯异氰脲酸或二溴异氰脲酸的金属盐，包含极性化合物如水和烷基二醇的水性溶剂体系和准亲水性化合物。 组合物可以配制成其中所有组分混合在一起的一部分体系。
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公开(公告)号：US20120108593A1
公开(公告)日：2012-05-03
申请号：US12806731
申请日：2010-08-19
摘要： An extreme temperature decontamination composition such as a solution for destroying microorganisms, chemical warfare and bioterrorism agents is utilized that generally does not freeze at low temperatures down to about minus 25° F. and also has no significant evaporation or decomposition at temperatures up to about 120° F. The solution is effective against nerve agents and vesicants such as VX and HD, and various biological agents. The composition comprises a metallic salt of dichloroisocyanuric acid or dibromoisocyanuric acid, an aqueous solvent system comprising polar compounds such as water and an alkyl glycol, and a quasi hydrophilic compound. The composition can be formulated as a one part system wherein all components are blended together.
摘要翻译： 使用极端温度去污组合物，例如用于破坏微生物的溶液，化学战和生物恐怖剂，其通常在低至约零下25摄氏度的低温下不会冷冻，并且在高达约120℃的温度下也没有明显的蒸发或分解 °F。该溶液对神经药物和Vesicants如VX和HD以及各种生物制剂有效。 该组合物包含二氯异氰脲酸或二溴异氰脲酸的金属盐，包含极性化合物如水和烷基二醇的水性溶剂体系和准亲水性化合物。 组合物可以配制成其中所有组分混合在一起的一部分体系。
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公开(公告)号：US20080176943A1
公开(公告)日：2008-07-24
申请号：US11880670
申请日：2007-07-24
申请人： Herbert J. Kaiser , Anchalee Thanavaro , Brandon W. Dell'Aringa , Bryan M. Tienes , Daniel A. Klein , George W. Wagner
发明人： Herbert J. Kaiser , Anchalee Thanavaro , Brandon W. Dell'Aringa , Bryan M. Tienes , Daniel A. Klein , George W. Wagner
CPC分类号： A61L2/186 , A01N59/00 , A62D3/38 , A62D2101/02 , A01N25/08 , A01N25/10 , A01N25/22 , A01N25/26 , A01N25/30 , A01N33/12 , A01N37/02 , A01N37/36 , A01N37/40 , A01N59/04 , A01N59/14 , A01N59/16 , A01N2300/00
摘要： A one part, solids containing decontamination blend composition comprises a solid acetyl donor coated with a compound that protects it from hydrolysis, a peroxygen source, optionally a catalyst, optionally a surfactant, and optionally a buffer. The decontamination blend composition is generally in a dry powder, particle, etc form or in a tablet, pill, etc form and is complete in and of itself in that no additional compounds are required prior to use and is readily distributed as a one package system. Upon the addition of water, a peroxygen compound such as hydrogen peroxide is formed, and peracetic acid is generated under alkaline conditions. The decontamination blend composition is particularly suitable for oxidizing various chemical and biological compounds thereby eradicating the same in situ as on surfaces, clothes, articles, and the like. Representative contaminants include mustard gas, nerve gas, bacterial toxins, anthrax, bird flu, and the like.
摘要翻译： 一部分固体含有去污混合物组合物包括涂覆有保护其免于水解的化合物的固体乙酰基供体，过氧源，任选的催化剂，任选的表面活性剂和任选的缓冲剂。 去污混合物组合物通常为干粉，颗粒等形式或片剂，丸剂等形式，并且本身完整且在使用之前不需要额外的化合物，并且易于作为一个包装系统分发 。 加入水后，形成过氧化氢等过氧化合物，在碱性条件下生成过乙酸。 去污混合物组合物特别适用于氧化各种化学和生物化合物，从而在表面，衣物，制品等上原位消除它们。 代表性的污染物包括芥子气，神经气体，细菌毒素，炭疽，禽流感等。
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