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公开(公告)号：US20130302869A1
公开(公告)日：2013-11-14
申请号：US13885478
申请日：2011-11-14
申请人： David Erickson , David Sinton
发明人： David Erickson , David Sinton
摘要： An optofluidic photobioreactor including an optical waveguide having an input, characterized by an evanescent optical field confined along an outer surface of the optical waveguide produced by radiation propagating in the optical waveguide, means for inputting light to the input of the optical waveguide, and a selected photosynthetic microorganism disposed substantially within the evanescent field. A method for optically exciting a photosynthetic microorganism for generating a biofuel, a biofuel precursor, or a biomass from the optically-excited photosynthetic microorganism involves irradiating the photosynthetic microorganism attached to the surface of the waveguide with an evanescent optical field from optical radiation propagating in the optical waveguide, and driving photosynthesis in the microorganism by the evanescent optical field.
摘要翻译： 一种光流体光生物反应器，包括具有输入的光波导，其特征在于沿着在光波导中传播的辐射产生的沿光波导的外表面限制的消逝光场，用于将光输入到光波导的输入的装置，以及选定的 光合微生物基本上设置在ev逝场内。 用于光学激发光合微生物以产生来自光激发光合微生物的生物燃料前体或生物质的方法包括用附着在波导表面上的光合微生物从光辐射传播的光辐射 光波导，并通过ev逝光场驱动微生物中的光合作用。
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公开(公告)号：US20090092882A1
公开(公告)日：2009-04-09
申请号：US11869277
申请日：2007-10-09
申请人： Erik Kjeang , David Sinton , Nedjib Djilali
发明人： Erik Kjeang , David Sinton , Nedjib Djilali
CPC分类号： H01M4/8605 , H01M8/188 , Y02E60/528
摘要： A microfluidic fuel cell with flow-through architecture is provided. The anode and the cathode are porous electrodes and comprise an interstitial pore network. A virtual insulator is located between the electrodes, in an electrolyte channel. The virtual insulator is comprised of a co-laminar flow of an electrolyte. An inlet directs substantially all the flow of liquid reactant through the porous electrode.
摘要翻译： 提供了一种具有流通结构的微流体燃料电池。 阳极和阴极是多孔电极并且包括间隙孔网络。 虚拟绝缘体位于电极之间，位于电解质通道中。 虚拟绝缘体由电解液的共层流构成。 入口基本上引导液体反应物的所有流动通过多孔电极。
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公开(公告)号：US10079391B2
公开(公告)日：2018-09-18
申请号：US11869277
申请日：2007-10-09
申请人： Erik Kjeang , David Sinton , Nedjib Djilali
发明人： Erik Kjeang , David Sinton , Nedjib Djilali
CPC分类号： H01M4/8605 , H01M8/188 , Y02E60/528
摘要： A microfluidic fuel cell with flow-through architecture is provided. The anode and the cathode are porous electrodes and comprise an interstitial pore network. A virtual insulator is located between the electrodes, in an electrolyte channel. The virtual insulator is comprised of a co-laminar flow of an electrolyte. An inlet directs substantially all the flow of liquid reactant through the porous electrode.
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公开(公告)号：US09518248B2
公开(公告)日：2016-12-13
申请号：US13885478
申请日：2011-11-14
申请人： David Erickson , David Sinton
发明人： David Erickson , David Sinton
摘要： An optofluidic photobioreactor including an optical waveguide having an input, characterized by an evanescent optical field confined along an outer surface of the optical waveguide produced by radiation propagating in the optical waveguide, means for inputting light to the input of the optical waveguide, and a selected photosynthetic microorganism disposed substantially within the evanescent field. A method for optically exciting a photosynthetic microorganism for generating a biofuel, a biofuel precursor, or a biomass from the optically-excited photosynthetic microorganism involves irradiating the photosynthetic microorganism attached to the surface of the waveguide with an evanescent optical field from optical radiation propagating in the optical waveguide, and driving photosynthesis in the microorganism by the evanescent optical field.
摘要翻译： 一种光流体光生物反应器，包括具有输入的光波导，其特征在于沿着在光波导中传播的辐射产生的沿光波导的外表面限制的消逝光场，用于将光输入到光波导的输入的装置，以及选定的 光合微生物基本上设置在ev逝场内。 用于光学激发光合微生物以产生来自光激发光合微生物的生物燃料前体或生物质的方法包括用附着在波导表面上的光合微生物从光辐射传播的光辐射 光波导，并通过ev逝光场驱动微生物中的光合作用。
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公开(公告)号：US20240272017A1
公开(公告)日：2024-08-15
申请号：US18437802
申请日：2024-02-09
摘要： A method for determining specific heat capacity of fluids includes: (a) injecting a reference fluid into at least one channel of a reference substrate and a sample fluid into at least one channel of a sample substrate; (b) establishing a temperature gradient along the at least one channel of each substrate; (c) measuring temperature differential between the reference and sample substrates along the temperature gradient for a stagnant condition to define a baseline temperature differential, and for each of a plurality of flowrate ratios of the reference and sample fluids flowing through respective channels; and (d) based on the measuring in (c), determining a thermally-balanced flowrate ratio at which the temperature differential corresponds to the baseline temperature differential, and evaluating the specific heat capacity of the sample fluid based on the thermally-balanced flowrate ratio.
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公开(公告)号：US20210354142A1
公开(公告)日：2021-11-18
申请号：US17238291
申请日：2021-04-23
申请人： David Sinton , Jason Riordon , Mohammad Simchi
发明人： David Sinton , Jason Riordon , Mohammad Simchi
摘要： A device for selecting sperm includes a stack of a plurality of layers of a material. The stack has an inlet end and an outlet end. Each layer of the material includes a plurality of sperm selection microchannels. Each sperm selection microchannel has a respective microchannel inlet at the inlet end of the stack and extends to a respective microchannel outlet at the outlet end of the stack.
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公开(公告)号：US20200069296A1
公开(公告)日：2020-03-05
申请号：US16553728
申请日：2019-08-28
申请人： FARHANG TARLAN , JASON RIORDON , DAVID SINTON , THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO
发明人： FARHANG TARLAN , JASON RIORDON , DAVID SINTON
IPC分类号： A61B10/00
摘要： The present invention provides a microfluidic device with a confined geometry for isolating a slither-capable subpopulation of sperm which is of higher quality than the raw sperm population. The proposed device isolates slither-capable sperm based on their ability to enter and traverse a confined region where 3D locomotion is restricted. The DNA integrity of the selected sperm was higher than that of the corresponding raw samples by 55% and 122% for donors and patients, respectively. In side-by-side testing this method outperforms current clinical selection methods, density gradient centrifugation and swim-up, as well as sperm selected via general motility. Slithering represents a viable selection mechanism, readily applicable to clinical workflows with the potential to improve outcomes for couples and offspring.
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