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    STENT HAVING VARIABLE PROPERTIES AND METHOD OF ITS USE
    1.
    发明申请
    STENT HAVING VARIABLE PROPERTIES AND METHOD OF ITS USE 有权
    具有可变性质的特性及其使用方法

    公开(公告)号：US20080281397A1

    公开(公告)日：2008-11-13

    申请号：US12177734

    申请日：2008-07-22

    申请人： Douglas P. Killion ,  James R. Lininger

    发明人： Douglas P. Killion ,  James R. Lininger

    IPC分类号： A61F2/82 ,  A61F2/84

    CPC分类号： A61F2/915 ,  A61F2/91 ,  A61F2002/91525 ,  A61F2002/91533 ,  A61F2002/91558 ,  A61F2250/0018 ,  A61F2250/0029 ,  A61F2250/0039 ,  A61F2250/0048

    摘要： A stent and method of its use, the stent in its expanded configuration, exhibiting varying outward radial force along its length. In use, the expanded stent is of a tapered configuration which provides greater force in vessel regions requiring greater force and less force in regions requiring less. In particular the stent is useful in the ostium regions and at areas of bifurcation in vessels. Varying force over the length of the stent is achieved by varying the number of elements, the density of elements, the thickness of the elements making up the stent body, and maintaining a substantially metal to artery ratio in the expanded stent over its length.

    摘要翻译： 支架及其使用方法，支架处于其扩张构型中，沿其长度呈现出不同的向外径向力。 在使用中，扩张的支架是锥形构造，其在需要更小的区域中需要更大的力和更小的力的容器区域中提供更大的力。 特别地，支架可用于口腔区域和血管中分叉区域。 通过改变元件的数量，元件的密度，构成支架主体的元件的厚度，并且在其长度上保持扩张的支架中的基本上金属与动脉的比例来实现支架长度上的变化力。

    Stent having variable properties and method of its use
    3.
    发明授权
    Stent having variable properties and method of its use 有权
    支架具有可变性质及其使用方法

    公开(公告)号：US07780719B2

    公开(公告)日：2010-08-24

    申请号：US12177734

    申请日：2008-07-22

    申请人： Douglas P. Killion ,  James R. Lininger

    发明人： Douglas P. Killion ,  James R. Lininger

    IPC分类号： A61F2/06

    CPC分类号： A61F2/915 ,  A61F2/91 ,  A61F2002/91525 ,  A61F2002/91533 ,  A61F2002/91558 ,  A61F2250/0018 ,  A61F2250/0029 ,  A61F2250/0039 ,  A61F2250/0048

    摘要： A stent and method of its use, the stent in its expanded configuration, exhibiting varying outward radial force along its length. In use, the expanded stent is of a tapered configuration which provides greater force in vessel regions requiring greater force and less force in regions requiring less. In particular the stent is useful in the ostium regions and at areas of bifurcation in vessels. Varying force over the length of the stent is achieved by varying the number of elements, the density of elements, the thickness of the elements making up the stent body, and maintaining a substantially metal to artery ratio in the expanded stent over its length.

    摘要翻译： 支架及其使用方法，支架处于其扩张构型中，沿其长度呈现出不同的向外径向力。 在使用中，扩张的支架是锥形构造，其在需要更小的区域中需要更大的力和更小的力的容器区域中提供更大的力。 特别地，支架可用于口腔区域和血管中分叉区域。 通过改变元件的数量，元件的密度，构成支架主体的元件的厚度，并且在其长度上保持扩张的支架中的基本上金属与动脉的比例来实现支架长度上的变化力。

    Stent having variable properties and method of its use
    5.
    发明授权
    Stent having variable properties and method of its use 有权
    支架具有可变性质及其使用方法

    公开(公告)号：US07402169B2

    公开(公告)日：2008-07-22

    申请号：US11356750

    申请日：2006-02-17

    申请人： Douglas P. Killion ,  James R. Lininger

    发明人： Douglas P. Killion ,  James R. Lininger

    IPC分类号： A61F2/06

    CPC分类号： A61F2/915 ,  A61F2/91 ,  A61F2002/91525 ,  A61F2002/91533 ,  A61F2002/91558 ,  A61F2250/0018 ,  A61F2250/0029 ,  A61F2250/0039 ,  A61F2250/0048

    摘要： A stent and method of its use, the stent in its expanded configuration, exhibiting varying outward radial force along its length. In use, the expanded stent is of a tapered configuration which provides greater force in vessel regions requiring greater force and less force in regions requiring less. In particular the stent is useful in the ostium regions and at areas of bifurcation in vessels. Varying force over the length of the stent is achieved by varying the number of elements, the density of elements, the thickness of the elements making up the stent body, and maintaining a substantially metal to artery ratio in the expanded stent over its length.

    摘要翻译： 支架及其使用方法，支架处于其扩张构型中，沿其长度呈现出不同的向外径向力。 在使用中，扩张的支架是锥形构造，其在需要更小的区域中需要更大的力和更小的力的容器区域中提供更大的力。 特别地，支架可用于口腔区域和血管中分叉区域。 通过改变元件的数量，元件的密度，构成支架主体的元件的厚度，并且在其长度上保持扩张的支架中的基本上金属与动脉的比例来实现支架长度上的变化力。

    Stent delivery system with perfusion
    6.
    发明授权
    Stent delivery system with perfusion 有权
    支架灌注系统

    公开(公告)号：US6139524A

    公开(公告)日：2000-10-31

    申请号：US174283

    申请日：1998-10-16

    申请人： Douglas P. Killion

    发明人： Douglas P. Killion

    IPC分类号： A61F2/82 ,  A61F2/06 ,  A61F2/84 ,  A61M25/12 ,  A61M29/02 ,  A61M29/00

    CPC分类号： A61M25/104 ,  A61F2/95 ,  A61M2025/1077 ,  A61M2025/1095

    摘要： An inventive perfusion catheter is disclosed which allows for the flow of a bodily fluid across the catheter while the catheter delivers a treatment device to a specified bodily location. The inventive perfusion catheter finds particular application in the delivery of a stent. The stent is deployed from a chamber having perfusion openings in the proximal and distal ends. The perfusion openings are constructed and arranged so as to allow the flow of a bodily fluid such as blood through the chamber.

    摘要翻译： 公开了一种创新的灌注导管，其允许体液跨过导管流动，同时导管将治疗装置递送到指定的身体位置。 本发明的灌注导管特别适用于支架的输送。 支架从近端和远端具有灌注开口的腔室展开。 灌注开口被构造和布置成允许体液如血液流过腔室。

    Stent having variable properties
    7.
    发明授权
    Stent having variable properties 失效
    支架具有可变属性

    公开(公告)号：US5938697A

    公开(公告)日：1999-08-17

    申请号：US34249

    申请日：1998-03-04

    申请人： Douglas P. Killion ,  James R. Lininger

    发明人： Douglas P. Killion ,  James R. Lininger

    IPC分类号： A61F2/00 ,  A61F2/91 ,  A61F2/915 ,  A61F2/06 ,  A61F2/04

    CPC分类号： A61F2/915 ,  A61F2/91 ,  A61F2002/91525 ,  A61F2002/91533 ,  A61F2002/91558 ,  A61F2250/0018 ,  A61F2250/0029 ,  A61F2250/0039 ,  A61F2250/0048

    摘要： A stent and method of its use, the stent in its expanded configuration, exhibiting varying outward radial force along its length. In use, the expanded stent is of a tapered configuration which provides greater force in vessel regions requiring greater force and less force in regions requiring less. In particular the stent is useful in the ostium regions and at areas of bifurcation in vessels. Varying force over the length of the stent is achieved by varying the number of elements, the density of elements, the thickness of the elements making up the stent body, and maintaining a substantially metal to artery ratio in the expanded stent over its length.

    摘要翻译： 支架及其使用方法，支架处于其扩张构型中，沿其长度呈现出不同的向外径向力。 在使用中，扩张的支架是锥形构造，其在需要更小的区域中需要更大的力和更小的力的容器区域中提供更大的力。 特别地，支架可用于口腔区域和血管中分叉区域。 通过改变元件的数量，元件的密度，构成支架主体的元件的厚度，并且在其长度上保持扩张的支架中的基本上金属与动脉的比例来实现支架长度上的变化力。

    Bioadhesive applicator and methods of sealing tissue punctures using same
    8.
    发明授权
    Bioadhesive applicator and methods of sealing tissue punctures using same 有权
    生物粘合剂施用器和使用其密封组织穿刺的方法

    公开(公告)号：US09192363B2

    公开(公告)日：2015-11-24

    申请号：US13106707

    申请日：2011-05-12

    申请人： Robert M. Vidlund ,  Douglas P. Killion

    发明人： Robert M. Vidlund ,  Douglas P. Killion

    IPC分类号： A61B17/08 ,  A61B17/00 ,  A61M5/19

    CPC分类号： A61B17/0057 ,  A61B2017/00495 ,  A61B2017/0065 ,  A61B2017/00654 ,  A61M5/19

    摘要： A closure device includes a delivery member, a sealing material applicator, and an expandable member. The delivery member is insertable through a tissue tract to a vessel puncture. The sealing material applicator is configured to supply a volume of sealing material to the delivery member and includes first and second multi-chamber devices and a valve assembly. Each chamber of the first and second multi-chamber devices holds a component of the sealing material, and operating the valve assembly permits mixing of at least some of the components prior to connecting the sealing material applicator to the delivery member. The expandable member is positionable within the vessel to temporarily seal closed the vessel puncture from within the vessel. The closure device is operable to deliver the sealing material from the sealing material applicator, through the delivery member, and to the tissue tract to seal closed the vessel puncture from outside the vessel.

    摘要翻译： 闭合装置包括输送构件，密封材料施加器和可膨胀构件。 递送构件可通过组织管道插入到血管穿刺中。 密封材料施加器构造成将一定体积的密封材料供应到输送构件，并且包括第一和第二多室装置和阀组件。 第一和第二多室装置的每个室保持密封材料的一部分，并且在将密封材料施用器连接到递送构件之前，操作阀组件允许混合至少一些部件。 可膨胀构件可定位在容器内以临时密封容器内的血管穿刺。 闭合装置可操作以将密封材料从密封材料施加器，通过递送构件输送到组织管道，以密封容器从容器外部穿刺。

    Intravascular dilation catheter
    10.
    发明授权
    Intravascular dilation catheter 失效
    血管内扩张导管

    公开(公告)号：US5921957A

    公开(公告)日：1999-07-13

    申请号：US274071

    申请日：1994-07-12

    申请人： Douglas P. Killion ,  David W. Lodin

    发明人： Douglas P. Killion ,  David W. Lodin

    IPC分类号： A61M25/00 ,  A61M29/02 ,  A61M29/00

    CPC分类号： A61M25/0068 ,  A61M25/0069 ,  A61M25/0074 ,  A61M2025/0081 ,  A61M2025/1093 ,  A61M2029/025 ,  A61M25/007 ,  A61M25/008 ,  A61M25/09 ,  A61M25/104

    摘要： A balloon dilation catheter which has a long shaft and an inflatable balloon connected to its distal end. The shaft includes a guide wire lumen which has an inner diameter that is substantially larger than the guide wire diameter used in the procedure. An atraumatic tip is connected to the distal end of the inflatable balloon and includes an aperture which the guide wire passes through. The diameter of the aperture remains constant but is substantially less than the inner diameter of the guide wire lumen and matches the maximum diameter of the guide wire used in the procedure. The atraumatic tip minimizes the potential for vascular damage and eliminates the need to change catheters or guide wires and thus reduces the time and cost of the PTA procedure. The tip also includes holes which allow for dye injection and pressure measurement while the guide wire extends through the aperture. Alternatively, the aperture may be compliant such that it can expand or contract to accommodate guide wires of different diameters. The compliant tip minimizes the circumferencial ledge between the distal end of the catheter and the guide wire and thereby minimizes the potential for vascular damage.

    摘要翻译： 一种球囊扩张导管，其具有连接到其远端的长轴和可充气气囊。 该轴包括导丝管腔，其内径大致大于在该过程中使用的导丝直径。 无创伤的尖端连接到可充气气囊的远端，并且包括导丝通过的孔。 孔的直径保持恒定，但是基本上小于导丝管内腔的内径并且匹配在该过程中使用的导丝的最大直径。 无创尖端使血管损伤的可能性最小化，并且不需要更换导管或导丝，从而减少PTA手术的时间和成本。 尖端还包括允许染色剂注入和压力测量的孔，同时导丝延伸穿过孔。 或者，孔可以是柔顺的，使得其可以膨胀或收缩以适应不同直径的导丝。 柔性尖端使导管远端和引导线之间的圆周突起最小化，从而使血管损伤的可能性最小化。