摘要:
We describe transgenic cells which are transformed with nucleic acid molecules which encode glucosyltransferase polypeptides involved in phenylpropanoid biosynthesis.
摘要:
Monoterpenoid esters that have been modified to include a sugar pendant group are disclosed. Plant glycosyltransferase enzymes are provided that function to add a sugar, typically glucose, to monoterpenoids in a bioreactor for the production of glycosylated monoterpenoid esters, together with nucleic acid molecules encoding such enzymes and vectors and transgenic cells including such nucleic acid molecules.
摘要:
We describe a microbial cell, typically a bacterial cell, genetically engineered to produce a modified sugar nucleotide, for example UDP glucuronic acid, and the use of the modified sugar to transfer glucuronic acid to small acceptor molecules.
摘要:
We describe a screening method for the identification of glycosyltransferase polypeptides that regioselectively modify aglycones and the use of said glycosyltransferase polypeptides to modify aglycones.
摘要:
We describe the production of nucleotide sugars other than uridine diphosphate glucose (UDP-glucose), for example UDP-rhamnose, and the use of these nucleotide sugars in the modification of acceptor molecules.
摘要:
We describe glycosyltransferase nucleic acids and proteins isolatable from Arabidopsis thaliana, transgenic cells expressing said glycosyltransferases, and bioreactors comprising said transgenic cells together with nutrient medium for supporting the growth of said cell that includes at least one exogenous substrate which is a substrate for said glycosyltransferase, and wherein said nutrient medium does not include an exogenous supply of UDP-glucose.
摘要:
The invention relates to transgenic cells which have been transformed with nucleic acids encoding glucosyltransferase polypeptides (GTases) and vectors for use in transformation of said cells.
摘要:
We describe glycosyltransferase polypeptides that modify sesquiterpenoids and including pharmaceutical compositions comprising glycosylated sesquiterpenoids; methods to treat diseases, in particular cancer, bacterial and fungal infections and also flavourings and scents comprising glycosylated sesquiterpenoids.
摘要:
The invention relates to transgenic cells which have been transformed with nucleic acids encoding glycosyltransferase polypeptides (GTases) and vectors for use in transformation of said cells.