公开(公告)号：US20100111417A1

公开(公告)日：2010-05-06

申请号：US12263618

申请日：2008-11-03

申请人： Benjamin Ward ,  Sing Bing Kang ,  Eric Bennett

发明人： Benjamin Ward ,  Sing Bing Kang ,  Eric Bennett

IPC分类号： G06K9/34

CPC分类号： G06T7/579 ,  G06T2207/10012 ,  G06T2207/10016 ,  G06T2207/20104 ,  H04N13/261

摘要： Two-dimensional (2D) video is converted into multi-view video. The 2D video is segmented to generate a temporally consistent segmented 2D video which is made up of a sequence of segmented frames. The multi-view video is generated by employing user-guided operations to generate depth assignments for the segments associated with user-assigned regions of the segmented frames, where a user-assigned region is formed from a group of contiguous segments selected by the user.

摘要翻译： 二维（2D）视频转换为多视角视频。 2D视频被分割以产生由分段帧序列组成的时间上一致的分割的2D视频。 多视点视频是通过采用用户指导的操作来生成与分段帧的用户分配区域相关联的片段的深度分配，其中由用户选择的一组连续片段形成用户分配的区域。

公开(公告)号：US20060099688A1

公开(公告)日：2006-05-11

申请号：US11317196

申请日：2005-12-22

申请人： Henrik Clausen ,  Rudi Steffensen ,  Eric Bennett

发明人： Henrik Clausen ,  Rudi Steffensen ,  Eric Bennett

IPC分类号： C12P21/06 ,  C12P19/04 ,  C07H21/04 ,  C12N9/10

CPC分类号： C12N9/1051

摘要： A novel gene defining a novel enzyme UDP-galactose: β-D-galactose-R 4-α-D-galactosyltransferase, termed α4Gal-T1, with unique enzymatic properties is disclosed. The invention provides isolated DNA molecules and DNA constructs encoding α4Gal-T1 and derivatives thereof by way of amino acid deletion, substitution or insertion exhibiting α4Gal-T1 activity, as well as cloning and expression vectors including such DNA, host cells comprising DNA encoding α4Gal-T1, and recombinant methods for providing α4Gal-T1. The enzyme α4Gal-T1 and α4Gal-active derivatives thereof are disclosed. Further, the invention discloses methods of obtaining α1, 4galactosyl glycosylated glycosphingolipids by use of an enzymatically active α4Gal-T1 protein thereof or by using cells stably transfected with a vector including DNA encoding an enzymatically active α4Gal-T1 protein as an expression system for recombinant production of such glycosphingolipids. Also a method for the identification of DNA sequence variations in the α4Gal-T1-coding exon by PCR, and detecting the presence of DNA sequence variation, are disclosed.

摘要翻译： 公开了一种新颖的基因，其定义了具有独特的酶学性质的新型酶UDP-半乳糖：β-D-半乳糖-R 4-α-D-半乳糖基转移酶，称为α4Gal-T1。 本发明提供分离的DNA分子和编码α4Gal-T1及其衍生物的DNA构建体，其通过氨基酸缺失，取代或插入表现出α4Gal-T1活性，以及​​克隆和表达载体，包括此类DNA，宿主细胞包含编码α4Gal- T1和用于提供α4Gal-T1的重组方法。 公开了其α4Gal-T1和α4Gal活性衍生物。 此外，本发明公开了通过使用其酶促活化的α4Gal-T1蛋白或通过使用包含编码酶活性α4Gal-T1蛋白的DNA稳定转染的细胞作为重组生产的表达系统来获得α1，4半乳糖基糖基化糖苷脂的方法 的这种糖鞘醇。 还公开了通过PCR鉴定α4Gal-T1编码外显子中的DNA序列变异并检测DNA序列变异的存在的方法。

公开(公告)号：US07023808B2

公开(公告)日：2006-04-04

申请号：US10743973

申请日：2003-12-23

申请人： David Alexander Ball ,  R. Eric Bennett ,  Martin Hesketh ,  John Galen Scudder ,  David D. Ward

发明人： David Alexander Ball ,  R. Eric Bennett ,  Martin Hesketh ,  John Galen Scudder ,  David D. Ward

IPC分类号： H04J1/16

CPC分类号： H04L45/56 ,  H04L45/04 ,  H04L45/12 ,  H04L45/44

摘要： A partial best path technique distributes route selection in a routing protocol implementation on a router. The technique also ensures that announced paths received from peers of the router (i.e., a “load”) are compared in a correct order to select best paths that are then used by the router to forward packets and to advertise to the peers. When employed in a distributed architecture, the technique further reduces memory usage. To that end, the partial best path technique enhances a best path selection algorithm executed by the router to enable dispersion of the received path load among processing nodes or elements of the router, while maintaining the ordering requirement of the algorithm. The partial best path technique essentially provides an enhancement to the best path selection algorithm that selects a subset of paths from a plurality of paths, with that subset being the minimal subset needed to select the best paths.

摘要翻译： 部分最佳路径技术在路由器上的路由协议实现中分配路由选择。 该技术还确保从路由器的对等端（即，“负载”）接收到的公告路径以正确的顺序进行比较，以选择最佳路径，然后由路由器用于转发数据包并向对等体通告。 当在分布式架构中使用时，该技术进一步减少内存使用。 为此，部分最佳路径技术增强了由路由器执行的最佳路径选择算法，以便在维护该算法的排序要求的同时，使路由器的处理节点或元素之间的接收路径负载分散。 部分最佳路径技术基本上为最佳路径选择算法提供了增强，该算法从多个路径中选择路径的子集，该子集是选择最佳路径所需的最小子集。

公开(公告)号：US20050026266A1

公开(公告)日：2005-02-03

申请号：US10705401

申请日：2003-11-10

申请人： Henrik Clausen ,  Eric Bennett

发明人： Henrik Clausen ,  Eric Bennett

IPC分类号： A61K38/00 ,  A61K38/14 ,  A61K38/17 ,  C07K14/47 ,  C12N9/10 ,  C12Q1/48 ,  C07H21/04

CPC分类号： C07K14/4726 ,  A61K38/14 ,  A61K38/1709 ,  C12N9/1051 ,  C12Q1/48 ,  G01N2500/00 ,  G01N2500/04 ,  G01N2500/10

摘要： Novel methods for identification of inhibitors or modulators of binding activities mediated by lectin domains of polypeptide GalNAc-transferases are disclosed. Direct binding activity of GalNAc-transferase lectins has been demonstrated for the first time and methods to measure lectin mediated binding of isolated lectins or enzymes with lectin domains are disclosed. The present invention specifically discloses a novel selective inhibitor of polypeptide GalNAc-transferase lectin domains, which provides a major advancement in that this inhibitor and related inhibitors sharing common characteristics of activity bind lectin domains without serving as acceptor substrate for glycosyltransferases involved in synthesis of O-glycans. This inhibitor is represented by the β-anomeric configuration of GalNAc-benzyl, GalNAcβ-benzyl. Methods for inhibiting intracellular transport, cell surface expression, and secretion of mucins and O-glycosylated glycoproteins without affecting O-glycosylation processing are disclosed using the novel selective inhibitor identified.

摘要翻译： 公开了用于鉴定由多肽GalNAc转移酶的凝集素结构域介导的结合活性的抑制剂或调节剂的新方法。 已经首次证明了GalNAc转移酶凝集素的直接结合活性，并且公开了测定凝血素介导的分离的凝集素或酶与凝集素结构域的结合的方法。 本发明特别公开了一种新型多肽GalNAc转移酶凝集素结构域的选择性抑制剂，其提供了主要进展，即该抑制剂和相关抑制剂共享活性的共同特征结合凝集素结构域，而不用作参与合成O-糖蛋白的糖基转移酶的受体底物， 聚糖。 该抑制剂由GalNAc-苄基，GalNAcβ-苄基的β-异头构型表示。 使用鉴定的新型选择性抑制剂公开了抑制细胞内转运，细胞表面表达和分泌粘蛋白和O-糖基化糖蛋白的方法，而不影响O-糖基化处理。

公开(公告)号：USD740722S1

公开(公告)日：2015-10-13

申请号：US29459725

申请日：2013-07-02

申请人： Eric Bennett ,  Patrick Nolan ,  Mike Dotsey

设计人： Eric Bennett ,  Patrick Nolan ,  Mike Dotsey

公开(公告)号：US20110238147A1

公开(公告)日：2011-09-29

申请号：US12888137

申请日：2010-09-22

申请人： Eric Bennett ,  Erin Vitus ,  Matt Vargas ,  Arani Bose ,  Stephen Pons ,  Ben Tompkins ,  David Barry

发明人： Eric Bennett ,  Erin Vitus ,  Matt Vargas ,  Arani Bose ,  Stephen Pons ,  Ben Tompkins ,  David Barry

IPC分类号： A61F2/84

CPC分类号： A61F2/95 ,  A61F2002/9511 ,  A61M25/01 ,  A61M25/0136 ,  A61M25/0147

摘要： A system for mechanically deploying intraluminal implants is disclosed. The system is used with an implant that is delivered and/or deployed via a pull wire and includes a handle having a funnel and receiving channel for receiving the pull wire, a slider having a thumb grip and a wedge, and a shuttle having a grabber for grasping the pull wire. The thumb grip is pulled proximally to retract the wedge to cause the grabber to grasp the wire and retract the shuttle but not the wire. An extension spring linked between the slider and the shuttle abruptly pulls the shuttle to retract the pull wire after the slider is fully retracted.

摘要翻译： 公开了一种用于机械部署管腔内植入物的系统。 该系统与通过拉线输送和/或部署的植入物一起使用，并且包括具有漏斗的手柄和用于接收拉线的接收通道，具有拇指手柄和楔块的滑块以及具有抓取器的梭子 用于抓住拉丝。 拇指把手被向近侧拉动以缩回楔块，以使抓取器抓住线并使梭子收回而不是线。 在滑块完全缩回之后，连接在滑块和梭子之间的拉伸弹簧突然拉动梭子以缩回拉线。

公开(公告)号：US20080038809A1

公开(公告)日：2008-02-14

申请号：US11870966

申请日：2007-10-11

申请人： Henrik CLAUSEN ,  Eric BENNETT

发明人： Henrik CLAUSEN ,  Eric BENNETT

IPC分类号： C07K14/42 ,  C12N9/10

CPC分类号： C07K14/4726 ,  A61K38/14 ,  A61K38/1709 ,  C12N9/1051 ,  C12Q1/48 ,  G01N2500/00 ,  G01N2500/04 ,  G01N2500/10

摘要： Novel methods for identification of inhibitors or modulators of binding activities mediated by lectin domains of polypeptide GalNAc-transferases are disclosed. Direct binding activity of GalNAc-transferase lectins has been demonstrated for the first time and methods to measure lectin mediated binding of isolated lectins or enzymes with lectin domains are disclosed. The present invention specifically discloses a novel selective inhibitor of polypeptide GalNAc-transferase lectin domains, which provides a major advancement in that this inhibitor and related inhibitors sharing common characteristics of activity bind lectin domains without serving as acceptor substrate for glycosyltransferases involved in synthesis of O-glycans. This inhibitor is represented by the O-anomeric configuration of GalNAc-benzyl, GalNAcβ-benzyl. Methods for inhibiting intracellular transport, cell surface expression, and secretion of mucins and O-glycosylated glycoproteins without affecting O-glycosylation processing are disclosed using the novel selective inhibitor identified.

摘要翻译： 公开了用于鉴定由多肽GalNAc转移酶的凝集素结构域介导的结合活性的抑制剂或调节剂的新方法。 已经首次证明了GalNAc转移酶凝集素的直接结合活性，并且公开了测定凝血素介导的分离的凝集素或酶与凝集素结构域的结合的方法。 本发明特别公开了一种新型多肽GalNAc转移酶凝集素结构域的选择性抑制剂，其提供了主要进展，即该抑制剂和相关抑制剂共享活性的共同特征结合凝集素结构域，而不用作参与合成O-糖蛋白的糖基转移酶的受体底物， 聚糖。 该抑制剂由GalNAc-苄基，GalNAcβ-苄基的O-端基构型表示。 使用鉴定的新型选择性抑制剂公开了抑制细胞内转运，细胞表面表达和分泌粘蛋白和O-糖基化糖蛋白的方法，而不影响O-糖基化处理。

公开(公告)号：US20050181437A1

公开(公告)日：2005-08-18

申请号：US11105796

申请日：2005-04-13

申请人： Henrik Clausen ,  Eric Bennett

发明人： Henrik Clausen ,  Eric Bennett

IPC分类号： C12N9/10 ,  C12Q1/68 ,  C07H21/04

CPC分类号： C12N9/1051

摘要： A novel gene defining a novel enzyme in the UDP-D-galactose: b-N-acetyl-glucosamine β-1,4-galactosyltransferase family, termed β4Gal-T2, with unique enzymatic properties is disclosed. The enzymatic activity of β4Gal-T2 is shown to be distinct from that of previously identified enzymes of this gene family. The invention discloses isolated DNA molecules and DNA constructs encoding β4Gal-T2 and derivatives thereof by way of amino acid deletion, substitution or insertion exhibiting β4Gal-T2 activity, as well as cloning and expression vectors including such DNA, cells transfected with the vectors, and recombinant methods for providing β4Gal-T2. The enzyme β4Gal-T2 and β4Gal-T2-active derivatives thereof are disclosed, in particular soluble derivatives comprising the catalytically active domain of β4Gal-T2. Further, the invention discloses methods of obtaining β-1,4-galactosyl glycosylated saccharides, glycopeptides or glycoproteins by use of an enzymically active β4Gal-T2 protein or fusion protein thereof or by using cells stably transfected with a vector including DNA encoding an enzymatically active β4Gal-T2 protein as an expression system for recombinant production of such glycopeptides or glycoproteins. Also a method for the identification of DNA sequence variations in the β4Gal-T2 gene by isolating DNA from a patient, amplifying β4Gal-T2-coding exons by PCR, and detecting the presence of DNA sequence variation, are disclosed.

摘要翻译： 公开了一种在UDP-D-半乳糖：b-N-乙酰葡糖胺β-1,4-半乳糖基转移酶家族中定义新的酶的新基因，称为β4Gal-T2，具有独特的酶学性质。 β4Gal-T2的酶活性显示与以前鉴定的该基因家族的酶不同。 本发明公开了分离的DNA分子和编码β4Gal-T2的DNA构建体及其衍生物，通过氨基酸缺失，取代或插入显示β4Gal-T2活性，以及​​克隆和表达载体，包括这种DNA，用载体转染的细胞，以及 提供β4Gal-T2的重组方法。 公开了酶β4Gal-T2和β4Gal-T2-活性衍生物，特别是包含β4Gal-T2的催化活性结构域的可溶性衍生物。 此外，本发明公开了通过使用酶活性β4Gal-T2蛋白或其融合蛋白或通过使用包含编码酶活性的DNA的载体稳定转染的细胞获得β-1,4-半乳糖基糖基化糖，糖肽或糖蛋白的方法 β4Gal-T2蛋白作为重组生产这种糖肽或糖蛋白的表达系统。 还公开了通过从患者中分离DNA，通过PCR扩增β4Gal-T2编码外显子并检测DNA序列变异的存在来鉴定β4Gal-T2基因中的DNA序列变异的方法。

公开(公告)号：USD482834S1

公开(公告)日：2003-11-25

申请号：US29167581

申请日：2002-09-18

申请人： Eric Bennett

设计人： Eric Bennett

公开(公告)号：US20130318476A1

公开(公告)日：2013-11-28

申请号：US13480138

申请日：2012-05-24

申请人： Aaron Sauve ,  Shamik Bandyopadhyay ,  Kathryn C. Lemson ,  Jannes Paul Peters ,  Eric Bennett ,  Ahmad Bilal

发明人： Aaron Sauve ,  Shamik Bandyopadhyay ,  Kathryn C. Lemson ,  Jannes Paul Peters ,  Eric Bennett ,  Ahmad Bilal

IPC分类号： G06F3/048

CPC分类号： G06F3/0484 ,  G06F3/04886 ,  G06F9/451 ,  G06F2221/2149 ,  H04N5/23216

摘要： A method and apparatus is provided for operating a mobile device having stored thereon a plurality of applications (“apps”) that are each configured to capture an image. The method includes receiving first user input data requesting invocation of a given one of the applications. The given application is launched by the user. After launching the given application a user interface is presented which serves as an entry point through which ail of the image capture applications stored on the mobile device are made available to the user.

摘要翻译： 提供了一种方法和装置，用于操作其上存储有多个应用程序（“应用程序”）的移动设备，每个应用程序被配置为捕获图像。 该方法包括接收请求调用给定一个应用的第一用户输入数据。 给定的应用程序由用户启动。 在启动给定应用程序之后，呈现用户界面，用户界面用作存储在移动设备上的图像捕获应用的一部分可供用户使用的入口点。