公开(公告)号：US08216396B2

公开(公告)日：2012-07-10

申请号：US12873191

申请日：2010-08-31

申请人： Bret A. Dooley ,  Christopher C. Lasley ,  Michael R. Mitchell ,  Robert R. Steele ,  Eric M. Tittelbaugh

发明人： Bret A. Dooley ,  Christopher C. Lasley ,  Michael R. Mitchell ,  Robert R. Steele ,  Eric M. Tittelbaugh

IPC分类号： A61F2/82 ,  C22C19/03

CPC分类号： A61F2/82 ,  A61B2017/00867 ,  A61C2201/007 ,  A61L31/022 ,  A61L31/121 ,  A61L31/14 ,  A61L2400/16 ,  C22F1/006

摘要： Articles made of shape memory alloys having improved fatigue performance and to methods of treating articles formed from shape memory alloy materials by pre-straining the articles (or desired portions of the articles) in a controlled manner so that the resultant articles exhibit improved fatigue performance. The shape memory articles are preferably medical devices, more preferably implantable medical devices. They are most preferably devices of nitinol shape memory alloy, most particularly that is superelastic at normal body temperature. The pre-straining method of the present invention as performed on such articles includes the controlled introduction of non-recoverable tensile strains greater than about 0.20% at the surface of a desired portion of a shape memory alloy article. Controlled pre-straining operations are performed on the shape-set nitinol metal to achieve non-recoverable tensile strain greater than about 0.20% at or near the surface of selected regions in the nitinol metal article. The pre-straining operations result in a significant increase in fatigue life of the selectively treated regions and an overall improvement in the fatigue performance of the device.

摘要翻译： 由具有改善的疲劳性能的形状记忆合金制成的制品以及通过以受控的方式预制品（或制品的所需部分）来处理由形状记忆合金材料形成的制品的方法，使得所得制品表现出改进的疲劳性能。 形状记忆物品优选是医疗装置，更优选可植入医疗装置。 它们最优选为镍钛诺形状记忆合金的装置，最特别的是在正常体温下是超弹性的。 对这种制品进行的本发明的预应变方法包括在形状记忆合金制品的期望部分的表面处控制引入大于约0.20％的不可恢复的拉伸应变。 在形状组成的镍钛诺金属上进行受控的预应变操作，以在镍钛诺金属制品的选定区域的表面处或附近实现大于约0.20％的不可恢复拉伸应变。 预应变操作导致选择性处理区域的疲劳寿命显着增加，并且整体提高了设备​​的疲劳性能。

公开(公告)号：US20120323298A1

公开(公告)日：2012-12-20

申请号：US13545750

申请日：2012-07-10

申请人： Bret A. Dooley ,  Christopher C. Lasley ,  Michael R. Mitchell ,  Robert R. Steele ,  Eric M. Tittelbaugh

发明人： Bret A. Dooley ,  Christopher C. Lasley ,  Michael R. Mitchell ,  Robert R. Steele ,  Eric M. Tittelbaugh

IPC分类号： A61F2/82 ,  A61F2/01

CPC分类号： A61F2/82 ,  A61B2017/00867 ,  A61C2201/007 ,  A61L31/022 ,  A61L31/121 ,  A61L31/14 ,  A61L2400/16 ,  C22F1/006

摘要： Articles made of shape memory alloys having improved fatigue performance and to methods of treating articles formed from shape memory alloy materials by pre-straining the articles (or desired portions of the articles) in a controlled manner so that the resultant articles exhibit improved fatigue performance. The shape memory articles are preferably medical devices, more preferably implantable medical devices. They are most preferably devices of nitinol shape memory alloy, most particularly that is superelastic at normal body temperature. The pre-straining method of the present invention as performed on such articles includes the controlled introduction of non-recoverable tensile strains greater than about 0.20% at the surface of a desired portion of a shape memory alloy article. Controlled pre-straining operations are performed on the shape-set nitinol metal to achieve non-recoverable tensile strain greater than about 0.20% at or near the surface of selected regions in the nitinol metal article.

摘要翻译： 由具有改善的疲劳性能的形状记忆合金制成的制品以及通过以受控的方式预制品（或制品的所需部分）来处理由形状记忆合金材料形成的制品的方法，使得所得制品表现出改进的疲劳性能。 形状记忆物品优选是医疗装置，更优选可植入医疗装置。 它们最优选为镍钛诺形状记忆合金的装置，最特别的是在正常体温下是超弹性的。 对这种制品进行的本发明的预应变方法包括在形状记忆合金制品的期望部分的表面处控制引入大于约0.20％的不可恢复的拉伸应变。 在形状组成的镍钛诺金属上进行受控的预应变操作，以在镍钛诺金属制品的选定区域的表面处或附近实现大于约0.20％的不可恢复拉伸应变。

公开(公告)号：US20100331946A1

公开(公告)日：2010-12-30

申请号：US12873191

申请日：2010-08-31

申请人： BRET A. DOOLEY ,  CHRISTOPHER C. LASLEY ,  MICHAEL R. MITCHELL ,  ROBERT R. STEELE ,  ERIC M. TITTELBAUGH

发明人： BRET A. DOOLEY ,  CHRISTOPHER C. LASLEY ,  MICHAEL R. MITCHELL ,  ROBERT R. STEELE ,  ERIC M. TITTELBAUGH

IPC分类号： A61F2/82 ,  A61F2/01

CPC分类号： A61F2/82 ,  A61B2017/00867 ,  A61C2201/007 ,  A61L31/022 ,  A61L31/121 ,  A61L31/14 ,  A61L2400/16 ,  C22F1/006

摘要： Articles made of shape memory alloys having improved fatigue performance and to methods of treating articles formed from shape memory alloy materials by pre-straining the articles (or desired portions of the articles) in a controlled manner so that the resultant articles exhibit improved fatigue performance. The shape memory articles are preferably medical devices, more preferably implantable medical devices. They are most preferably devices of nitinol shape memory alloy, most particularly that is superelastic at normal body temperature. The pre-straining method of the present invention as performed on such articles includes the controlled introduction of non-recoverable tensile strains greater than about 0.20% at the surface of a desired portion of a shape memory alloy article. Controlled pre-straining operations are performed on the shape-set nitinol metal to achieve non-recoverable tensile strain greater than about 0.20% at or near the surface of selected regions in the nitinol metal article. The pre-straining operations result in a significant increase in fatigue life of the selectively treated regions and an overall improvement in the fatigue performance of the device.

摘要翻译： 由具有改善的疲劳性能的形状记忆合金制成的制品以及通过以受控的方式预制品（或制品的所需部分）来处理由形状记忆合金材料形成的制品的方法，使得所得制品表现出改进的疲劳性能。 形状记忆物品优选是医疗装置，更优选可植入医疗装置。 它们最优选为镍钛诺形状记忆合金的装置，最特别的是在正常体温下是超弹性的。 对这种制品进行的本发明的预应变方法包括在形状记忆合金制品的期望部分的表面处控制引入大于约0.20％的不可恢复的拉伸应变。 在形状组成的镍钛诺金属上进行受控的预应变操作，以在镍钛诺金属制品的选定区域的表面处或附近实现大于约0.20％的不可恢复拉伸应变。 预应变操作导致选择性处理区域的疲劳寿命显着增加，并且整体提高了设备​​的疲劳性能。

公开(公告)号：US09107733B2

公开(公告)日：2015-08-18

申请号：US11331754

申请日：2006-01-13

申请人： Edward H Cully ,  Cody L. Hartman ,  Craig T. Nordhausen ,  Eric M. Tittelbaugh ,  Michael J. Vonesh

发明人： Edward H Cully ,  Cody L. Hartman ,  Craig T. Nordhausen ,  Eric M. Tittelbaugh ,  Michael J. Vonesh

IPC分类号： A61M29/00 ,  A61F2/01 ,  A61B17/221 ,  A61B17/22 ,  A61F2/06

CPC分类号： A61F2/01 ,  A61B17/221 ,  A61B2017/22035 ,  A61B2017/2212 ,  A61F2002/011 ,  A61F2002/016 ,  A61F2002/068 ,  A61F2230/0006 ,  A61F2230/005 ,  A61F2230/0065 ,  A61F2230/008 ,  A61F2230/0093

摘要： The present invention relates to a non-evertable blood filter that divides the transverse cross sectional area of a venous vessel into three annular regions or zones. The inner zone, the region immediately surrounding the longitudinal axis of the vessel, is maintained in a relatively open state with only minimal interference from the members making up the filter device so that blood flow can be maintained at a relatively normal rate. Concentrically surrounding the inner zone is the intermediate zone, to which captured emboli are directed out of the bloodstream passing primarily through the inner zone. Finally, concentrically surrounding the intermediate zone is the outer zone adjacent to the vessel wall. This is also intended to be kept free of emboli, so that emboli in the bloodstream immediately adjacent the vessel wall are directed away from the wall by the filter design and into the intermediate zone, thereby avoiding the accumulation of emboli adjacent the vessel wall that might otherwise result in stenosis. The blood filter is intended primarily for use as an inferior vena cava filter, although it can be made in a range of sizes allowing its use in blood vessels and particularly venous vessels of differing diameters. The filter is preferably removable.

摘要翻译： 本发明涉及将静脉血管的横截面积分为三个环形区域或不同区域的不可转换血液过滤器。 内部区域即立即围绕容器的纵向轴线的区域被保持在相对打开的状态，其中构成过滤装置的构件只有最小的干扰，使得可以将血流维持在相对正常的速率。 集中地围绕内部区域是中间区域，被捕获的栓塞被引导到主要穿过内部区域的血流中。 最后，同心围绕中间区域是与血管壁相邻的外部区域。 这也意在保持没有栓塞，使得紧邻血管壁的血液中的栓塞通过过滤器设计被引导离开壁并进入中间区域，从而避免邻近容器壁的栓塞积聚 否则会导致狭窄。 血液过滤器主要用作下腔静脉过滤器，尽管它可以制成一系列尺寸，允许其用于血管，特别是不同直径的静脉血管。 过滤器优选是可移除的。

公开(公告)号：US07811393B2

公开(公告)日：2010-10-12

申请号：US11557274

申请日：2006-11-07

申请人： Bret A. Dooley ,  Christopher C. Lasley ,  Michael R. Mitchell ,  Robert R. Steele ,  Eric M. Tittelbaugh

发明人： Bret A. Dooley ,  Christopher C. Lasley ,  Michael R. Mitchell ,  Robert R. Steele ,  Eric M. Tittelbaugh

IPC分类号： A61F2/06 ,  C22C19/03

CPC分类号： A61F2/82 ,  A61B2017/00867 ,  A61C2201/007 ,  A61L31/022 ,  A61L31/121 ,  A61L31/14 ,  A61L2400/16 ,  C22F1/006

摘要： Articles made of shape memory alloys having improved fatigue performance and to methods of treating articles formed from shape memory alloy materials by pre-straining the articles (or desired portions of the articles) in a controlled manner so that the resultant articles exhibit improved fatigue performance. The shape memory articles are preferably medical devices, more preferably implantable medical devices. They are most preferably devices of nitinol shape memory alloy, most particularly that is superelastic at normal body temperature. The pre-straining method of the present invention as performed on such articles includes the controlled introduction of non-recoverable tensile strains greater than about 0.20% at the surface of a desired portion of a shape memory alloy article. Controlled pre-straining operations are performed on the shape-set nitinol metal to achieve non-recoverable tensile strain greater than about 0.20% at or near the surface of selected regions in the nitinol metal article. The pre-straining operations result in a significant increase in fatigue life of the selectively treated regions and an overall improvement in the fatigue performance of the device.

摘要翻译： 由具有改善的疲劳性能的形状记忆合金制成的制品以及通过以受控的方式预制品（或制品的所需部分）来处理由形状记忆合金材料形成的制品的方法，使得所得制品表现出改进的疲劳性能。 形状记忆物品优选是医疗装置，更优选可植入医疗装置。 它们最优选为镍钛诺形状记忆合金的装置，最特别的是在正常体温下是超弹性的。 对这种制品进行的本发明的预应变方法包括在形状记忆合金制品的期望部分的表面处控制引入大于约0.20％的不可恢复的拉伸应变。 在形状组成的镍钛诺金属上进行受控的预应变操作，以在镍钛诺金属制品的选定区域的表面处或附近实现大于约0.20％的不可恢复拉伸应变。 预应变操作导致选择性处理区域的疲劳寿命显着增加，并且整体提高了设备​​的疲劳性能。

公开(公告)号：US07789979B2

公开(公告)日：2010-09-07

申请号：US10428872

申请日：2003-05-02

申请人： Bret A. Dooley ,  Christopher C. Lasley ,  Michael R. Mitchell ,  Robert R. Steele ,  Eric M. Tittelbaugh

发明人： Bret A. Dooley ,  Christopher C. Lasley ,  Michael R. Mitchell ,  Robert R. Steele ,  Eric M. Tittelbaugh

IPC分类号： C23F1/10

CPC分类号： A61F2/82 ,  A61B2017/00867 ,  A61C2201/007 ,  A61L31/022 ,  A61L31/121 ,  A61L31/14 ,  A61L2400/16 ,  C22F1/006

摘要： Articles made of shape memory alloys having improved fatigue performance and to methods of treating articles formed from shape memory alloy materials by pre-straining the articles (or desired portions of the articles) in a controlled manner so that the resultant articles exhibit improved fatigue performance. The shape memory articles are preferably medical devices, more preferably implantable medical devices. They are most preferably devices of nitinol shape memory alloy, most particularly that is superelastic at normal body temperature. The pre-straining method of the present invention as performed on such articles includes the controlled introduction of non-recoverable tensile strains greater than about 0.20% at the surface of a desired portion of a shape memory alloy article. Controlled pre-straining operations are performed on the shape-set nitinol metal to achieve nonrecoverable tensile strain greater than about 0.20% at or near the surface of selected regions in the nitinol metal article. The pre-straining operations result in a significant increase in fatigue life of the selectively treated regions and an overall improvement in the fatigue performance of the device.

摘要翻译： 由具有改善的疲劳性能的形状记忆合金制成的制品以及通过以受控的方式预制品（或制品的所需部分）来处理由形状记忆合金材料形成的制品的方法，使得所得制品表现出改进的疲劳性能。 形状记忆物品优选是医疗装置，更优选可植入医疗装置。 它们最优选为镍钛诺形状记忆合金的装置，最特别的是在正常体温下是超弹性的。 对这种制品进行的本发明的预应变方法包括在形状记忆合金制品的期望部分的表面处控制引入大于约0.20％的不可恢复的拉伸应变。 在形状固定的镍钛诺金属上进行受控的预应变操作，以在镍钛诺金属制品的选定区域的表面处或附近实现大于约0.20％的不可恢复的拉伸应变。 预应变操作导致选择性处理区域的疲劳寿命显着增加，并且整体提高了设备​​的疲劳性能。

公开(公告)号：US09839540B2

公开(公告)日：2017-12-12

申请号：US13298060

申请日：2011-11-16

申请人： Joseph R. Armstrong ,  Edward H. Cully ,  Michael W. Franklin ,  Mark Y. Hansen ,  Brandon A. Lurie ,  Craig R. McMurray ,  William D. Montgomery ,  Wendy J. Terry ,  Eric M. Tittelbaugh

发明人： Joseph R. Armstrong ,  Edward H. Cully ,  Michael W. Franklin ,  Mark Y. Hansen ,  Brandon A. Lurie ,  Craig R. McMurray ,  William D. Montgomery ,  Wendy J. Terry ,  Eric M. Tittelbaugh

IPC分类号： A61F2/915 ,  A61F2/88 ,  A61F2/07 ,  A61F2/966 ,  A61F2/958

CPC分类号： A61F2/88 ,  A61F2/07 ,  A61F2/915 ,  A61F2/966 ,  A61F2002/075 ,  A61F2002/91558 ,  A61F2002/91575 ,  A61F2002/9583 ,  A61F2220/005 ,  A61F2220/0075 ,  A61F2230/0054

摘要： The invention relates to a medical device and a method of using it. The device is a stent which can be percutaneously deliverable with (or on) an endovascular catheter or via other surgical or other techniques and then expanded. The stent is configured to have a central portion defined by “open” cells and at least two end portions, defined by “closed” cells, spaced apart and directly connected to the distal and proximal ends of the central portion of the stent. The stent may also optionally have a covering or a lattice with openings.

公开(公告)号：US08709177B2

公开(公告)日：2014-04-29

申请号：US13545750

申请日：2012-07-10

申请人： Bret A. Dooley ,  Christopher C. Lasley ,  Michael R. Mitchell ,  Robert R. Steele ,  Eric M. Tittelbaugh

发明人： Bret A. Dooley ,  Christopher C. Lasley ,  Michael R. Mitchell ,  Robert R. Steele ,  Eric M. Tittelbaugh

IPC分类号： A61F2/01 ,  A61F2/06 ,  C22C19/03

CPC分类号： A61F2/82 ,  A61B2017/00867 ,  A61C2201/007 ,  A61L31/022 ,  A61L31/121 ,  A61L31/14 ,  A61L2400/16 ,  C22F1/006

摘要： Articles made of shape memory alloys having improved fatigue performance and to methods of treating articles formed from shape memory alloy materials by pre-straining the articles (or desired portions of the articles) in a controlled manner so that the resultant articles exhibit improved fatigue performance. The shape memory articles are preferably medical devices, more preferably implantable medical devices. They are most preferably devices of nitinol shape memory alloy, most particularly that is superelastic at normal body temperature. The pre-straining method of the present invention as performed on such articles includes the controlled introduction of non-recoverable tensile strains greater than about 0.20% at the surface of a desired portion of a shape memory alloy article. Controlled pre-straining operations are performed on the shape-set nitinol metal to achieve non-recoverable tensile strain greater than about 0.20% at or near the surface of selected regions in the nitinol metal article.

摘要翻译： 由具有改善的疲劳性能的形状记忆合金制成的制品以及通过以受控的方式预制品（或制品的所需部分）来处理由形状记忆合金材料形成的制品的方法，使得所得制品表现出改进的疲劳性能。 形状记忆物品优选是医疗装置，更优选可植入医疗装置。 它们最优选为镍钛诺形状记忆合金的装置，最特别的是在正常体温下是超弹性的。 对这种制品进行的本发明的预应变方法包括在形状记忆合金制品的期望部分的表面处控制引入大于约0.20％的不可恢复的拉伸应变。 在形状组成的镍钛诺金属上进行受控的预应变操作，以在镍钛诺金属制品的选定区域的表面处或附近实现大于约0.20％的不可恢复拉伸应变。

公开(公告)号：US20120303112A1

公开(公告)日：2012-11-29

申请号：US13298060

申请日：2011-11-16

申请人： Joseph R. Armstrong ,  Edward H. Cully ,  Michael W. Franklin ,  Mark Y. Hansen ,  Brandon A. Lurie ,  Craig r. McMurray ,  William D. Montgomery ,  Wendy J. Terry ,  Eric M. Tittelbaugh

发明人： Joseph R. Armstrong ,  Edward H. Cully ,  Michael W. Franklin ,  Mark Y. Hansen ,  Brandon A. Lurie ,  Craig r. McMurray ,  William D. Montgomery ,  Wendy J. Terry ,  Eric M. Tittelbaugh

IPC分类号： A61F2/82

CPC分类号： A61F2/88 ,  A61F2/07 ,  A61F2/915 ,  A61F2/966 ,  A61F2002/075 ,  A61F2002/91558 ,  A61F2002/91575 ,  A61F2002/9583 ,  A61F2220/005 ,  A61F2220/0075 ,  A61F2230/0054

摘要： The invention relates to a medical device and a method of using it. The device is a stent which can be percutaneously deliverable with (or on) an endovascular catheter or via other surgical or other techniques and then expanded. The stent is configured to have a central portion defined by “open” cells and at least two end portions, defined by “closed” cells, spaced apart and directly connected to the distal and proximal ends of the central portion of the stent. The stent may also optionally have a covering or a lattice with openings.

摘要翻译： 本发明涉及医疗装置及其使用方法。 该装置是可以通过（或在）血管内导管或经由其它手术或其它技术经皮递送的支架，然后扩张。 支架被构造成具有由开放细胞限定的中心部分和由闭孔限定的至少两个端部，间隔开并且直接连接到支架的中心部分的远端和近端。 支架也可任选地具有带开口的覆盖物或格子。

公开(公告)号：US08177927B2

公开(公告)日：2012-05-15

申请号：US12873175

申请日：2010-08-31

申请人： Bret A. Dooley ,  Christopher C. Lasley ,  Michael R. Mitchell ,  Robert R. Steele ,  Eric M. Tittelbaugh

发明人： Bret A. Dooley ,  Christopher C. Lasley ,  Michael R. Mitchell ,  Robert R. Steele ,  Eric M. Tittelbaugh

IPC分类号： C22F1/10

CPC分类号： A61F2/82 ,  A61B2017/00867 ,  A61C2201/007 ,  A61L31/022 ,  A61L31/121 ,  A61L31/14 ,  A61L2400/16 ,  C22F1/006

摘要： A method of making articles made of shape memory alloys having improved fatigue performance and to methods of treating articles formed from shape memory alloy materials by pre-straining the articles (or desired portions of the articles) in a controlled manner so that the resultant articles exhibit improved fatigue performance. The shape memory articles are preferably medical devices, more preferably implantable medical devices. They are most preferably devices of nitinol shape memory alloy, most particularly that is superelastic at normal body temperature. The pre-straining method of the present invention as performed on such articles includes the controlled introduction of non-recoverable tensile strains greater than about 0.20% at the surface of a desired portion of a shape memory alloy article. Controlled pre-straining operations are performed on the shape-set nitinol metal to achieve non-recoverable tensile strain greater than about 0.20% at or near the surface of selected regions in the nitinol metal article. The pre-straining operations result in a significant increase in fatigue life of the selectively treated regions and an overall improvement in the fatigue performance of the device.

摘要翻译： 制造具有改善的疲劳性能的形状记忆合金制品的方法以及通过以受控的方式预应变制品（或制品的所需部分）来处理由形状记忆合金材料形成的制品的方法，使得所得制品展现 改善疲劳性能。 形状记忆物品优选是医疗装置，更优选可植入医疗装置。 它们最优选为镍钛诺形状记忆合金的装置，最特别的是在正常体温下是超弹性的。 对这种制品进行的本发明的预应变方法包括在形状记忆合金制品的期望部分的表面处控制引入大于约0.20％的不可恢复的拉伸应变。 在形状组成的镍钛诺金属上进行受控的预应变操作，以在镍钛诺金属制品的选定区域的表面处或附近实现大于约0.20％的不可恢复拉伸应变。 预应变操作导致选择性处理区域的疲劳寿命显着增加，并且整体提高了设备​​的疲劳性能。