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公开(公告)号：US20100041031A1
公开(公告)日：2010-02-18
申请号：US12217471
申请日：2008-07-03
申请人： Eric D. Schwoebel , James D. Harper , Martha S. Petrovick , Frances E. Nargi , Todd H. Rider , Kristine E. Hogan , Richard H. Mathews , Joseph Lacirignola , Mark Hennessy , Trina R. Vian , Rose M. Joseph , Raymond S. Uttaro , Shaun Berry , Bernadette Johnson , Mark A. Hollis
发明人： Eric D. Schwoebel , James D. Harper , Martha S. Petrovick , Frances E. Nargi , Todd H. Rider , Kristine E. Hogan , Richard H. Mathews , Joseph Lacirignola , Mark Hennessy , Trina R. Vian , Rose M. Joseph , Raymond S. Uttaro , Shaun Berry , Bernadette Johnson , Mark A. Hollis
IPC分类号： C12Q1/68 , G01N33/566 , G01N21/00 , C12M1/34
CPC分类号： G01N33/5304 , C12M1/3461 , C12M1/3476 , C12Q1/6825 , G01N21/6428 , G01N21/6454 , G01N33/582 , C12Q2565/619 , C12Q2563/131
摘要： The invention described herein provides methods for the detection of soluble antigens. In particular, the methods provide for the detection of soluble proteins and chemicals. In addition, the invention provides methods of detecting a nucleic acid sequence in a sample. Also described is an emittor cell comprising an Fc receptor and an emittor molecule for the detection of a target particle in a sample wherein the target particle to be detected is bound by one or more antibodies. Also provided is an optoelectronic sensor device for detecting a target particle in a plurality of samples.
摘要翻译： 本文描述的本发明提供了用于检测可溶性抗原的方法。 特别地，该方法提供了可溶性蛋白质和化学物质的检测。 此外，本发明提供了检测样品中核酸序列的方法。 还描述了包含Fc受体和发射体分子的发射体细胞，用于检测样品中的靶颗粒，其中待检测的靶颗粒被一种或多种抗体结合。 还提供了一种用于检测多个样品中的目标颗粒的光电传感器装置。
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公开(公告)号：US08835127B2
公开(公告)日：2014-09-16
申请号：US13267276
申请日：2011-10-06
申请人： Eric D. Schwoebel , James D. Harper , Martha S. Petrovick , Frances E. Nargi , Todd H. Rider , Kristine E. Hogan , Richard H. Mathews , Joseph Lacirignola , Mark Hennessy , Trina R. Vian , Rose M. Joseph , Raymond S. Uttaro , Shaun Berry , Bernadette Johnson , Mark A. Hollis
发明人： Eric D. Schwoebel , James D. Harper , Martha S. Petrovick , Frances E. Nargi , Todd H. Rider , Kristine E. Hogan , Richard H. Mathews , Joseph Lacirignola , Mark Hennessy , Trina R. Vian , Rose M. Joseph , Raymond S. Uttaro , Shaun Berry , Bernadette Johnson , Mark A. Hollis
CPC分类号： G01N33/5304 , C12M1/3461 , C12M1/3476 , C12Q1/6825 , G01N21/6428 , G01N21/6454 , G01N33/582 , C12Q2565/619 , C12Q2563/131
摘要： The invention described herein provides methods for the detection of soluble antigens. In particular, the methods provide for the detection of soluble proteins and chemicals. In addition, the invention provides methods of detecting a nucleic acid sequence in a sample. Also described is an emittor cell comprising an Fc receptor and an emittor molecule for the detection of a target particle in a sample wherein the target particle to be detected is bound by one or more antibodies. Also provided is an optoelectronic sensor device for detecting a target particle in a plurality of samples.
摘要翻译： 本文描述的本发明提供了用于检测可溶性抗原的方法。 特别地，该方法提供了可溶性蛋白质和化学物质的检测。 此外，本发明提供了检测样品中核酸序列的方法。 还描述了包含Fc受体和发射体分子的发射体细胞，用于检测样品中的靶颗粒，其中待检测的靶颗粒被一种或多种抗体结合。 还提供了一种用于检测多个样品中的目标颗粒的光电传感器装置。
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公开(公告)号：US20090221056A1
公开(公告)日：2009-09-03
申请号：US12085486
申请日：2006-11-30
IPC分类号： C12N1/12
CPC分类号： A01N1/02 , A01N1/0226
摘要： Methods to produce cells that remain viable at ambient or non-refrigerated temperatures, or which can be stored in a dry state are described. In particular, cell preservation is for long term storage of cells, such as mammalian cells, at ambient or non-refrigerated temperatures, while retaining cell viability. Also provided are sensor cells that can detect target particles, biological agents or other materials and which remain viable at ambient or non-refrigerated temperatures, or which can be stored in a dry state.
摘要翻译： 描述了生产在环境或非冷藏温度下保持活性或可以以干燥状态储存的细胞的方法。 特别地，细胞保存用于在环境或非冷藏温度下长期储存诸如哺乳动物细胞的细胞，同时保持细胞活力。 还提供了可以检测目标颗粒，生物制剂或其它材料并且在环境或非冷藏温度下保持活性或可以以干燥状态储存的传感器细胞。
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公开(公告)号：US20080166705A1
公开(公告)日：2008-07-10
申请号：US11001583
申请日：2004-12-01
申请人： Eric D. Schwoebel , James D. Harper , Martha S. Petrovick , Frances E. Nargi , Todd H. Rider , Kristine E. Hogan , Richard H. Mathews , Joseph Lacirignola , Mark Hennessy , Trina R. Vian , Rose M. Joseph , Raymond S. Uttaro , Shaun Berry , Bernadette Johnson , Mark A. Hollis
发明人： Eric D. Schwoebel , James D. Harper , Martha S. Petrovick , Frances E. Nargi , Todd H. Rider , Kristine E. Hogan , Richard H. Mathews , Joseph Lacirignola , Mark Hennessy , Trina R. Vian , Rose M. Joseph , Raymond S. Uttaro , Shaun Berry , Bernadette Johnson , Mark A. Hollis
CPC分类号： G01N33/5304 , C12M1/3461 , C12M1/3476 , C12Q1/6825 , G01N21/6428 , G01N21/6454 , G01N33/582 , C12Q2565/619 , C12Q2563/131
摘要： The invention described herein provides methods for the detection of soluble antigens. In particular, the methods provide for the detection of soluble proteins and chemicals. In addition, the invention provides methods of detecting a nucleic acid sequence in a sample. Also described is an emittor cell comprising an Fc receptor and an emittor molecule for the detection of a target particle in a sample wherein the target particle to be detected is bound by one or more antibodies. Also provided is an optoelectronic sensor device for detecting a target particle in a plurality of samples.
摘要翻译： 本文描述的本发明提供了用于检测可溶性抗原的方法。 特别地，该方法提供了可溶性蛋白质和化学物质的检测。 此外，本发明提供了检测样品中核酸序列的方法。 还描述了包含Fc受体和发射体分子的发射体细胞，用于检测样品中的靶颗粒，其中待检测的靶颗粒被一种或多种抗体结合。 还提供了一种用于检测多个样品中的目标颗粒的光电传感器装置。
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公开(公告)号：US20120135404A1
公开(公告)日：2012-05-31
申请号：US13267276
申请日：2011-10-06
申请人： Eric. D. Schwoebel , James D. Harper , Martha S. Petrovick , Frances E. Nargi , Todd H. Rider , Kristine E. Hogan , Richard H. Mathews , Joseph Lacirignola , Mark Hennessy , Trina R. Vian , Rose M. Joseph , Raymond S. Uttaro , Shaun Berry , Bernadette Johnson , Mark A. Hollis
发明人： Eric. D. Schwoebel , James D. Harper , Martha S. Petrovick , Frances E. Nargi , Todd H. Rider , Kristine E. Hogan , Richard H. Mathews , Joseph Lacirignola , Mark Hennessy , Trina R. Vian , Rose M. Joseph , Raymond S. Uttaro , Shaun Berry , Bernadette Johnson , Mark A. Hollis
CPC分类号： G01N33/5304 , C12M1/3461 , C12M1/3476 , C12Q1/6825 , G01N21/6428 , G01N21/6454 , G01N33/582 , C12Q2565/619 , C12Q2563/131
摘要： The invention described herein provides methods for the detection of soluble antigens. In particular, the methods provide for the detection of soluble proteins and chemicals. In addition, the invention provides methods of detecting a nucleic acid sequence in a sample. Also described is an emittor cell comprising an Fc receptor and an emittor molecule for the detection of a target particle in a sample wherein the target particle to be detected is bound by one or more antibodies. Also provided is an optoelectronic sensor device for detecting a target particle in a plurality of samples.
摘要翻译： 本文描述的本发明提供了用于检测可溶性抗原的方法。 特别地，该方法提供了可溶性蛋白质和化学物质的检测。 此外，本发明提供了检测样品中核酸序列的方法。 还描述了包含Fc受体和发射体分子的发射体细胞，用于检测样品中的靶颗粒，其中待检测的靶颗粒被一种或多种抗体结合。 还提供了一种用于检测多个样品中的目标颗粒的光电传感器装置。
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公开(公告)号：US08067184B2
公开(公告)日：2011-11-29
申请号：US12217471
申请日：2008-07-03
申请人： Eric D. Schwoebel , James D. Harper , Martha S. Petrovick , Frances E. Nargi , Todd H. Rider , Kristine E. Hogan , Richard H. Mathews , Joseph Lacirignola , Mark Hennessy , Trina R. Vian , Rose M. Joseph , Raymond S. Uttaro , Shaun Berry , Bernadette Johnson , Mark A. Hollis
发明人： Eric D. Schwoebel , James D. Harper , Martha S. Petrovick , Frances E. Nargi , Todd H. Rider , Kristine E. Hogan , Richard H. Mathews , Joseph Lacirignola , Mark Hennessy , Trina R. Vian , Rose M. Joseph , Raymond S. Uttaro , Shaun Berry , Bernadette Johnson , Mark A. Hollis
CPC分类号： G01N33/5304 , C12M1/3461 , C12M1/3476 , C12Q1/6825 , G01N21/6428 , G01N21/6454 , G01N33/582 , C12Q2565/619 , C12Q2563/131
摘要： The invention described herein provides methods for the detection of soluble antigens. In particular, the methods provide for the detection of soluble proteins and chemicals. In addition, the invention provides methods of detecting a nucleic acid sequence in a sample. Also described is an emittor cell comprising an Fc receptor and an emittor molecule for the detection of a target particle in a sample wherein the target particle to be detected is bound by one or more antibodies. Also provided is an optoelectronic sensor device for detecting a target particle in a plurality of samples.
摘要翻译： 本文描述的本发明提供了用于检测可溶性抗原的方法。 特别地，该方法提供了可溶性蛋白质和化学物质的检测。 此外，本发明提供了检测样品中核酸序列的方法。 还描述了包含Fc受体和发射体分子的发射体细胞，用于检测样品中的靶颗粒，其中待检测的靶颗粒被一种或多种抗体结合。 还提供了一种用于检测多个样品中的目标颗粒的光电传感器装置。
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公开(公告)号：US07422860B2
公开(公告)日：2008-09-09
申请号：US11001583
申请日：2004-12-01
申请人： Eric D. Schwoebel , James D. Harper , Martha S. Petrovick , Frances E. Nargi , Todd H. Rider , Kristine E. Hogan , Richard H. Mathews , Joseph Lacirignola , Mark Hennessy , Trina R. Vian , Rose M. Joseph , Raymond S. Uttaro , Shaun Berry , Bernadette Johnson , Mark A. Hollis
发明人： Eric D. Schwoebel , James D. Harper , Martha S. Petrovick , Frances E. Nargi , Todd H. Rider , Kristine E. Hogan , Richard H. Mathews , Joseph Lacirignola , Mark Hennessy , Trina R. Vian , Rose M. Joseph , Raymond S. Uttaro , Shaun Berry , Bernadette Johnson , Mark A. Hollis
IPC分类号： G01N33/53
CPC分类号： G01N33/5304 , C12M1/3461 , C12M1/3476 , C12Q1/6825 , G01N21/6428 , G01N21/6454 , G01N33/582 , C12Q2565/619 , C12Q2563/131
摘要： The invention described herein provides methods for the detection of soluble antigens. In particular, the methods provide for the detection of soluble proteins and chemicals. In addition, the invention provides methods of detecting a nucleic acid sequence in a sample. Also described is an emittor cell comprising an Fc receptor and an emittor molecule for the detection of a target particle in a sample wherein the target particle to be detected is bound by one or more antibodies. Also provided is an optoelectronic sensor device for detecting a target particle in a plurality of samples.
摘要翻译： 本文描述的本发明提供了用于检测可溶性抗原的方法。 特别地，该方法提供了可溶性蛋白质和化学物质的检测。 此外，本发明提供了检测样品中核酸序列的方法。 还描述了包含Fc受体和发射体分子的发射体细胞，用于检测样品中的靶颗粒，其中待检测的靶颗粒被一种或多种抗体结合。 还提供了一种用于检测多个样品中的目标颗粒的光电传感器装置。
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