公开(公告)号：US20170352538A1

公开(公告)日：2017-12-07

申请号：US15613396

申请日：2017-06-05

申请人： Jeehwan Kim ,  Dirk Robert ENGLUND ,  Mark A. HOLLIS ,  Travis WADE ,  Michael GEIS ,  Richard MOLNAR

发明人： Jeehwan Kim ,  Dirk Robert ENGLUND ,  Mark A. HOLLIS ,  Travis WADE ,  Michael GEIS ,  Richard MOLNAR

IPC分类号： H01L21/02 ,  H01L21/306 ,  H01L29/04 ,  H01L21/683 ,  H01L21/3213 ,  H01L29/16

CPC分类号： H01L21/02527 ,  H01L21/02376 ,  H01L21/02444 ,  H01L21/0245 ,  H01L21/02499 ,  H01L21/02598 ,  H01L21/0262 ,  H01L21/02639 ,  H01L21/02645 ,  H01L21/02647 ,  H01L21/30604 ,  H01L21/32133 ,  H01L21/6835 ,  H01L29/04 ,  H01L29/1602 ,  H01L29/1606 ,  H01L29/66015 ,  H01L2221/68363 ,  H01L2221/68381 ,  H01L2221/68386

摘要： A buffer layer is employed to fabricate diamond membranes and allow reuse of diamond substrates. In this approach, diamond membranes are fabricated on the buffer layer, which in turn is disposed on a diamond substrate that is lattice-matched to the diamond membrane. The weak bonding between the buffer layer and the diamond substrate allows ready release of the fabricated diamond membrane. The released diamond membrane is transferred to another substrate to fabricate diamond devices, while the diamond substrate is reused for another fabrication.

公开(公告)号：US09671670B2

公开(公告)日：2017-06-06

申请号：US14294422

申请日：2014-06-03

申请人： Mark A. Hollis ,  Reuel B. Swint ,  Dominic Siriani ,  Joseph P. Donnelly ,  Paul William Juodawlkis

发明人： Mark A. Hollis ,  Reuel B. Swint ,  Dominic Siriani ,  Joseph P. Donnelly ,  Paul William Juodawlkis

IPC分类号： G02F1/035 ,  G02F1/225 ,  G02B6/14 ,  G02F1/017 ,  G02B6/12 ,  G02F1/21

CPC分类号： G02F1/2255 ,  G02B6/14 ,  G02B2006/12097 ,  G02F1/01708 ,  G02F1/01716 ,  G02F1/2257 ,  G02F2001/212 ,  G02F2201/12

摘要： An electro-optic modulator imparts the information contained in an electrical signal traveling along a transmission line onto an optical carrier by using signal-related variations in the electrical signal's voltage to modulate the refractive index or absorption in an electro-optic material through which the optical carrier propagates. For optimal bandwidth and modulation efficiency, the microwave and optical waves should be matched in velocity. However, conventional microwave transmission lines have a microwave velocity that is somewhat higher than the optical group velocity in typical optical waveguides. Tuning a microwave transmission line's capacitance reduces the microwave velocity, but also reduces the impedance below the 50Ω impedance of most microwave components. Conversely, tuning the microwave transmission line's inductance makes it possible to match the microwave velocity to the optical group velocity over bandwidths of 100 GHz or greater while maintaining a microwave impedance of 50Ω.

公开(公告)号：US08835127B2

公开(公告)日：2014-09-16

申请号：US13267276

申请日：2011-10-06

申请人： Eric D. Schwoebel ,  James D. Harper ,  Martha S. Petrovick ,  Frances E. Nargi ,  Todd H. Rider ,  Kristine E. Hogan ,  Richard H. Mathews ,  Joseph Lacirignola ,  Mark Hennessy ,  Trina R. Vian ,  Rose M. Joseph ,  Raymond S. Uttaro ,  Shaun Berry ,  Bernadette Johnson ,  Mark A. Hollis

发明人： Eric D. Schwoebel ,  James D. Harper ,  Martha S. Petrovick ,  Frances E. Nargi ,  Todd H. Rider ,  Kristine E. Hogan ,  Richard H. Mathews ,  Joseph Lacirignola ,  Mark Hennessy ,  Trina R. Vian ,  Rose M. Joseph ,  Raymond S. Uttaro ,  Shaun Berry ,  Bernadette Johnson ,  Mark A. Hollis

IPC分类号： G01N33/53 ,  C12Q1/68 ,  G01N21/64 ,  G01N33/58

CPC分类号： G01N33/5304 ,  C12M1/3461 ,  C12M1/3476 ,  C12Q1/6825 ,  G01N21/6428 ,  G01N21/6454 ,  G01N33/582 ,  C12Q2565/619 ,  C12Q2563/131

摘要： The invention described herein provides methods for the detection of soluble antigens. In particular, the methods provide for the detection of soluble proteins and chemicals. In addition, the invention provides methods of detecting a nucleic acid sequence in a sample. Also described is an emittor cell comprising an Fc receptor and an emittor molecule for the detection of a target particle in a sample wherein the target particle to be detected is bound by one or more antibodies. Also provided is an optoelectronic sensor device for detecting a target particle in a plurality of samples.

摘要翻译： 本文描述的本发明提供了用于检测可溶性抗原的方法。 特别地，该方法提供了可溶性蛋白质和化学物质的检测。 此外，本发明提供了检测样品中核酸序列的方法。 还描述了包含Fc受体和发射体分子的发射体细胞，用于检测样品中的靶颗粒，其中待检测的靶颗粒被一种或多种抗体结合。 还提供了一种用于检测多个样品中的目标颗粒的光电传感器装置。

公开(公告)号：US20080166705A1

公开(公告)日：2008-07-10

申请号：US11001583

申请日：2004-12-01

申请人： Eric D. Schwoebel ,  James D. Harper ,  Martha S. Petrovick ,  Frances E. Nargi ,  Todd H. Rider ,  Kristine E. Hogan ,  Richard H. Mathews ,  Joseph Lacirignola ,  Mark Hennessy ,  Trina R. Vian ,  Rose M. Joseph ,  Raymond S. Uttaro ,  Shaun Berry ,  Bernadette Johnson ,  Mark A. Hollis

发明人： Eric D. Schwoebel ,  James D. Harper ,  Martha S. Petrovick ,  Frances E. Nargi ,  Todd H. Rider ,  Kristine E. Hogan ,  Richard H. Mathews ,  Joseph Lacirignola ,  Mark Hennessy ,  Trina R. Vian ,  Rose M. Joseph ,  Raymond S. Uttaro ,  Shaun Berry ,  Bernadette Johnson ,  Mark A. Hollis

IPC分类号： C12Q1/68 ,  G01N33/53 ,  C12M1/34

CPC分类号： G01N33/5304 ,  C12M1/3461 ,  C12M1/3476 ,  C12Q1/6825 ,  G01N21/6428 ,  G01N21/6454 ,  G01N33/582 ,  C12Q2565/619 ,  C12Q2563/131

摘要： The invention described herein provides methods for the detection of soluble antigens. In particular, the methods provide for the detection of soluble proteins and chemicals. In addition, the invention provides methods of detecting a nucleic acid sequence in a sample. Also described is an emittor cell comprising an Fc receptor and an emittor molecule for the detection of a target particle in a sample wherein the target particle to be detected is bound by one or more antibodies. Also provided is an optoelectronic sensor device for detecting a target particle in a plurality of samples.

摘要翻译： 本文描述的本发明提供了用于检测可溶性抗原的方法。 特别地，该方法提供了可溶性蛋白质和化学物质的检测。 此外，本发明提供了检测样品中核酸序列的方法。 还描述了包含Fc受体和发射体分子的发射体细胞，用于检测样品中的靶颗粒，其中待检测的靶颗粒被一种或多种抗体结合。 还提供了一种用于检测多个样品中的目标颗粒的光电传感器装置。

公开(公告)号：US20080131949A1

公开(公告)日：2008-06-05

申请号：US11804598

申请日：2007-05-18

申请人： Laura T. Bortolin ,  Lalitha Parameswaran ,  James Harper ,  Johanna Bobrow ,  Mark A. Hollis ,  Drew Chapman Brown ,  Eric Scott Clasen ,  John Calvin Schmidt

发明人： Laura T. Bortolin ,  Lalitha Parameswaran ,  James Harper ,  Johanna Bobrow ,  Mark A. Hollis ,  Drew Chapman Brown ,  Eric Scott Clasen ,  John Calvin Schmidt

IPC分类号： C12N13/00 ,  C12M1/00

CPC分类号： B01L3/502 ,  B01L2200/10 ,  B01L2200/16 ,  B01L2300/042 ,  B01L2300/043 ,  B01L2300/044 ,  B01L2300/047 ,  B01L2300/048 ,  B01L2300/0609 ,  B01L2300/0672 ,  B01L2300/0681 ,  B01L2300/069 ,  B01L2300/0867 ,  B01L2300/1822 ,  B01L2300/1827 ,  B01L2400/043 ,  B01L2400/0644 ,  B01L2400/0683 ,  C07H21/04 ,  C12N15/1013

摘要： A method for preparing a nucleic acid component of a sample for amplification includes contacting the sample with a porous support that deactivates a nucleic acid amplification inhibitor component of the sample and directing a fluid through the porous support, whereby the nucleic acid component of the sample is directed through at least a portion of the porous support and is separated from the support, thereby preparing the nucleic acid component for amplification. The sample is separated from raw sample components through means that include a magnetic substrate. An apparatus suitable for conducting the method of the invention also is described.

摘要翻译： 用于制备用于扩增的样品的核酸组分的方法包括使样品与多孔载体接触，多孔载体使样品的核酸扩增抑制剂组分失活并引导流体通过多孔载体，由此样品的核酸组分为 引导通过多孔载体的至少一部分并与载体分离，由此制备用于扩增的核酸组分。 样品通过包括磁性底物的方式与原始样品组分分离。 还描述了适用于进行本发明的方法的装置。

公开(公告)号：US5332918A

公开(公告)日：1994-07-26

申请号：US938385

申请日：1992-08-31

申请人： Frank W. Smith ,  Mark A. Hollis ,  Arthur R. Calawa ,  Vicky Diadiuk ,  Han Q. Le

发明人： Frank W. Smith ,  Mark A. Hollis ,  Arthur R. Calawa ,  Vicky Diadiuk ,  Han Q. Le

IPC分类号： H01L21/20 ,  H01L21/285 ,  H01L21/335 ,  H01L21/337 ,  H01L21/338 ,  H01L21/8252 ,  H01L29/10 ,  H01L29/51 ,  H01L29/812 ,  H01L31/09 ,  H01L31/18 ,  H01S5/02 ,  H01S5/026 ,  H01S5/223 ,  H01L27/14 ,  H01L23/485 ,  H01L31/00

CPC分类号： H01L29/517 ,  H01L21/28587 ,  H01L21/8252 ,  H01L29/1075 ,  H01L29/66462 ,  H01L29/66863 ,  H01L29/66924 ,  H01L29/8128 ,  H01L31/09 ,  H01L31/184 ,  H01L21/02395 ,  H01L21/02463 ,  H01L21/02546 ,  H01L21/02631 ,  H01S5/0208 ,  H01S5/021 ,  H01S5/026 ,  H01S5/223 ,  Y02E10/544

摘要： An ultra-high-speed photoconductive device is described which comprises a homoepitaxial semi-insulating III-V layer, or body, upon which ohmic/conductive contacts, or strips, separated by a small gap, are formed. The semi-insulating body, or layer, is produced by low temperature growth of III-V compounds by MBE. In a GaAs embodiment, the layer is grown under arsenic stable growth conditions, at a substrate temperature preferably in the range of 150.degree. to about 300.degree. C.

摘要翻译： 描述了一种超高速光电导器件，其包括同质外延半绝缘III-V层或体，在其上形成由小间隙分开的欧姆/导电触点或条带。 半绝缘体或层是通过MBE的III-V化合物的低温生长而产生的。 在GaAs实施方案中，该层在砷稳定生长条件下生长，在衬底温度下优选在150℃至约300℃的范围内。

公开(公告)号：US4839310A

公开(公告)日：1989-06-13

申请号：US149125

申请日：1988-01-27

申请人： Mark A. Hollis ,  William D. Goodhue ,  Kirby B. Nichols ,  Normand J. Bergeron, Jr.

发明人： Mark A. Hollis ,  William D. Goodhue ,  Kirby B. Nichols ,  Normand J. Bergeron, Jr.

IPC分类号： C23C14/22 ,  H01L21/285 ,  H01L21/335 ,  H01L21/338 ,  H01L29/06 ,  H01L29/10 ,  H01L29/423 ,  H01L29/778 ,  H01L29/812

CPC分类号： C23C14/225 ,  H01L21/28587 ,  H01L21/28593 ,  H01L29/0653 ,  H01L29/0657 ,  H01L29/1029 ,  H01L29/42316 ,  H01L29/66462 ,  H01L29/66856 ,  H01L29/7785 ,  H01L29/7787 ,  H01L29/7788 ,  H01L29/7789 ,  H01L29/8122 ,  Y10S438/944

摘要： Horizontal and vertical transistors, such as, HEMT/SDHT devices are described with opposed gates for preventing substrate leakage current along with the methods for making same. Also a process for making single gate angled V-HEMT devices is described.

摘要翻译： 描述了HEMT / SDHT器件的水平和垂直晶体管，其具有用于防止衬底漏电流的相对栅极及其制造方法。 还描述了制造单门角V-HEMT器件的过程。

公开(公告)号：US09991113B2

公开(公告)日：2018-06-05

申请号：US15613396

申请日：2017-06-05

申请人： Jeehwan Kim ,  Dirk Robert Englund ,  Mark A. Hollis ,  Travis Wade ,  Michael Geis ,  Richard Molnar

发明人： Jeehwan Kim ,  Dirk Robert Englund ,  Mark A. Hollis ,  Travis Wade ,  Michael Geis ,  Richard Molnar

IPC分类号： H01L21/20 ,  H01L21/02 ,  H01L21/306 ,  H01L21/3213 ,  H01L21/683 ,  H01L29/04 ,  H01L29/16

CPC分类号： H01L21/02527 ,  H01L21/02376 ,  H01L21/02444 ,  H01L21/0245 ,  H01L21/02499 ,  H01L21/02598 ,  H01L21/0262 ,  H01L21/02639 ,  H01L21/02645 ,  H01L21/02647 ,  H01L21/30604 ,  H01L21/32133 ,  H01L21/6835 ,  H01L29/04 ,  H01L29/1602 ,  H01L29/1606 ,  H01L29/66015 ,  H01L2221/68363 ,  H01L2221/68381 ,  H01L2221/68386

摘要： A buffer layer is employed to fabricate diamond membranes and allow reuse of diamond substrates. In this approach, diamond membranes are fabricated on the buffer layer, which in turn is disposed on a diamond substrate that is lattice-matched to the diamond membrane. The weak bonding between the buffer layer and the diamond substrate allows ready release of the fabricated diamond membrane. The released diamond membrane is transferred to another substrate to fabricate diamond devices, while the diamond substrate is reused for another fabrication.

公开(公告)号：US5168069A

公开(公告)日：1992-12-01

申请号：US312133

申请日：1989-02-17

申请人： Frank W. Smith ,  Mark A. Hollis ,  Arthur R. Calawa ,  Vicky Diadiuk ,  Han Q. Le

发明人： Frank W. Smith ,  Mark A. Hollis ,  Arthur R. Calawa ,  Vicky Diadiuk ,  Han Q. Le

IPC分类号： H01L21/20 ,  H01L21/285 ,  H01L21/335 ,  H01L21/337 ,  H01L21/338 ,  H01L21/8252 ,  H01L29/10 ,  H01L29/51 ,  H01L29/812 ,  H01L31/09 ,  H01L31/18 ,  H01S5/02 ,  H01S5/026 ,  H01S5/223

CPC分类号： H01L29/517 ,  H01L21/02395 ,  H01L21/02463 ,  H01L21/02546 ,  H01L21/02631 ,  H01L21/02634 ,  H01L21/28587 ,  H01L21/8252 ,  H01L29/1075 ,  H01L29/66462 ,  H01L29/66863 ,  H01L29/66924 ,  H01L29/8128 ,  H01L31/09 ,  H01L31/184 ,  H01S5/0208 ,  H01S5/021 ,  H01S5/026 ,  H01S5/223 ,  Y02E10/544 ,  Y02P70/521 ,  Y10S148/003 ,  Y10S148/025 ,  Y10S148/041 ,  Y10S148/056 ,  Y10S148/154 ,  Y10S438/971

摘要： An ultra-high-speed photoconductive device is described which comprises a homoepitaxial semi-insulating III-V layer, or body, upon which ohmic/conductive contacts, or strips, separated by a small gap, are formed. The semi-insulating body, or layer, is produced by low temperature growth of III-V compounds by MBE. In a GaAs embodiment, the layer is grown under arsenic stable growth conditions, at a substrate temperature preferably in the range of 150.degree. to about 300.degree. C.

摘要翻译： 描述了一种超高速光电导器件，其包括同质外延半绝缘III-V层或体，在其上形成由小间隙分开的欧姆/导电触点或条带。 半绝缘体或层是通过MBE的III-V化合物的低温生长而产生的。 在GaAs实施方案中，该层在砷稳定生长条件下生长，在衬底温度下优选在150℃至约300℃的范围内。

公开(公告)号：US20160202592A1

公开(公告)日：2016-07-14

申请号：US14294422

申请日：2014-06-03

申请人： Mark A. Hollis ,  Reuel B. Swint ,  Dominic Siriani ,  Joseph P. Donnelly ,  Paul William Juodawlkis

发明人： Mark A. Hollis ,  Reuel B. Swint ,  Dominic Siriani ,  Joseph P. Donnelly ,  Paul William Juodawlkis

IPC分类号： G02F1/225 ,  G02F1/017 ,  G02B6/14

CPC分类号： G02F1/2255 ,  G02B6/14 ,  G02B2006/12097 ,  G02F1/01708 ,  G02F1/01716 ,  G02F1/2257 ,  G02F2001/212 ,  G02F2201/12

摘要： An electro-optic modulator imparts the information contained in an electrical signal traveling along a transmission line onto an optical carrier by using signal-related variations in the electrical signal's voltage to modulate the refractive index or absorption in an electro-optic material through which the optical carrier propagates. For optimal bandwidth and modulation efficiency, the microwave and optical waves should be matched in velocity. However, conventional microwave transmission lines have a microwave velocity that is somewhat higher than the optical group velocity in typical optical waveguides. Tuning a microwave transmission line's capacitance reduces the microwave velocity, but also reduces the impedance below the 50Ω impedance of most microwave components. Conversely, tuning the microwave transmission line's inductance makes it possible to match the microwave velocity to the optical group velocity over bandwidths of 100 GHz or greater while maintaining a microwave impedance of 50Ω.

摘要翻译： 电光调制器通过使用电信号电压中的信号相关变化将包含在沿着传输线行进的电信号中的信息传递到光载体上，以调制电光材料中的折射率或吸收，通过光电材料 载波传播。 为了获得最佳的带宽和调制效率，微波和光波的速度应该匹配。 然而，传统的微波传输线的微波速度略高于典型光波导中的光群速度。 调谐微波传输线的电容降低了微波的速度，同时也降低了低于50Ω的阻抗; 大部分微波元件的阻抗。 相反，调谐微波传输线的电感可以使微波速度与100 GHz或更大带宽上的光学组速度相匹配，同时保持微波阻抗为50Ω。