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1.发明授权Devices to resist migration and rotation of implants used in brachytherapy and other radiation therapy 有权用于抵抗近距离放射治疗和其他放射治疗中使用的植入物的迁移和旋转的装置公开(公告)号：US08790235B2
公开(公告)日：2014-07-29
申请号：US12538028
申请日：2009-08-07
IPC分类号： A61M36/12
CPC分类号： A61N5/1027 , A61N2005/1023 , A61N2005/1024
摘要： A therapeutic member for use in brachytherapy deliverable to an implant site by way of a needle comprises a single radioactive source encapsulated by a bio-absorbable material having an outer surface including one or more ribs encircling the single radioactive source, a leading edge endcap rib and a trailing edge endcap rib. The one or more ribs reduces a tendency of the member to migrate and rotate within a patient's body after implantation. The encapsulating material further includes a first rail formed from the bio-absorbable material extending at least from opposite sides of the outer surface of the encapsulating material along the longitudinal axis of the therapeutic member, and a second rail formed from the bio-absorbable material extending at least from opposite sides of the outer surface of the encapsulating material along the longitudinal axis of the therapeutic member, the second rail arranged in a plane substantially perpendicular to a plane in which the first rail is arranged. Another embodiment includes wings that selectively extend from an implant preventing movement of the implant.
摘要翻译： 用于通过针可递送到植入部位的近距离放射治疗的治疗部件包括由生物可吸收材料包封的单个放射源，所述生物可吸收材料具有外表面，该外表面包括环绕单个放射源的一个或多个肋，前缘端盖肋和 后缘端盖肋。 一个或多个肋降低了植入后患者身体内迁移和旋转的倾向。 封装材料还包括由生物可吸收材料形成的第一轨道，其至少从包封材料的外表面的相对侧沿着治疗构件的纵向轴线延伸，以及由生物可吸收材料形成的第二轨道 至少从包封材料的外表面的相对侧沿着施疗件的纵向轴线，第二导轨布置成大致垂直于第一导轨布置的平面的平面。 另一个实施例包括从防止植入物移动的植入体选择性延伸的翼。
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公开(公告)号：US07942803B2
公开(公告)日：2011-05-17
申请号：US12691508
申请日：2010-01-21
IPC分类号： A61N5/00
CPC分类号： A61N5/1027 , A61N5/1007 , A61N2005/1023 , A61N2005/1024 , B29C47/0009 , B29C47/021 , B29C47/028 , G21G4/08
摘要： A prescription method of treating tissue comprises the steps of accepting a prescription tissue treatment plan for the tissue to be treated, positioning seeds relative to each other per the prescription tissue treatment plan such that the positions of seeds relative to each other is only established by the prescription tissue treatment plan, and creating a treatment strand by heating and cooling a material to position the plurality of treatment seeds in the material. The prescription tissue treatment plan specifies a number and a spacing of the seeds to be provided in the treatment strand, the spacing of the treatment seeds being unrestricted by any use of spacers and independently set by and according to the prescription tissue treatment plan.
摘要翻译： 处理组织的处方方法包括以下步骤：接受处理组织的处方组织处理计划，根据处方组织处理计划相对于彼此定位种子，使得种子相对于彼此的位置仅由 处方组织处理计划，以及通过加热和冷却材料以将多种处理种子定位在材料中来形成治疗股。 处方组织处理计划规定了要在治疗链中提供的种子的数量和间距，处理种子的间距通过任何使用间隔物而不受限制，并且根据处方组织处理计划独立设定。
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公开(公告)号：US07874976B1
公开(公告)日：2011-01-25
申请号：US11517649
申请日：2006-09-07
IPC分类号： A61M36/00
CPC分类号： A61N5/1027 , A61B2090/3925 , A61N2005/1023
摘要： Echogenic strands and spacers are provided for use in brachytherapy. Methods of making the strands and spacers are also provided. An echogenic strand for use in brachytherapy includes an encapsulating material, a seed disposed within the encapsulating material, and a spacer disposed within the encapsulating material and arranged adjacent to the seed. The spacer has an external length and a chamber formed along the external length, the chamber being adapted to improve ultrasound visibility relative to the spacer.
摘要翻译： 提供了生长性丝束和间隔物用于近距离放射治疗。 还提供了制造股线和间隔物的方法。 用于近距离放射治疗的回声链包括封装材料，设置在封装材料内的种子以及设置在封装材料内且邻近晶种布置的间隔物。 间隔件具有外部长度和沿着外部长度形成的腔室，腔室适于改善相对于间隔件的超声可见性。
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4.发明授权Delivery system and method for interstitial radiation therapy using custom end spacing 失效使用定制末端间距的间质放射治疗的输送系统和方法公开(公告)号：US07736295B2
公开(公告)日：2010-06-15
申请号：US11274424
申请日：2005-11-15
IPC分类号： A61N5/00
CPC分类号： A61M37/0069 , A61B17/3468 , A61B2017/3407 , A61B2017/3411 , A61N5/1027 , A61N2005/1012 , A61N2005/1023
摘要： A delivery system and method for interstitial radiation therapy comprising a strand made of material, which is bio-absorbable in living tissue and a plurality of radioactive seeds dispersed in a predetermined array within the strand. The strands can have custom end spacings, which allow the optimal placing of seeds within the treatment tissue by implanting a plurality of strands to the same depth. A plurality of these strands can be implanted at the same time by the use of a guiding device. In certain embodiments, a custom end spacing within a needle is not attached to the strand in the needle. In certain embodiments, the custom end spacing, seeds and spacers within a needle are loose, i.e., not part of a strand.
摘要翻译： 用于间质放射治疗的递送系统和方法，包括由活体组织中可生物吸收的材料制成的股线，以及以预定阵列分散在股线内的多个放射性种子。 股线可以具有定制的端部间隔，其允许通过将多个股线植入同一深度来最佳地将种子放置在处理组织内。 可以通过使用引导装置同时植入多个这些线。 在某些实施例中，针内的定制端部间隔未附接到针中的股线。 在某些实施例中，针内的定制端间距，种子和间隔物是松散的，即不是绞线的一部分。
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5.发明申请IMPLANTS FOR USE IN BRACHYTHERAPY AND OTHER RADIATION THERAPY THAT RESIST MIGRATION AND ROTATION 审中-公开用于BRACHYTHERAPY和其他辐射治疗的植入物，可抵抗移动和旋转公开(公告)号：US20090149692A1
公开(公告)日：2009-06-11
申请号：US12388436
申请日：2009-02-18
IPC分类号： A61M36/12
CPC分类号： A61N5/1027 , A61N2005/1023 , A61N2005/1024
摘要： In an embodiment a therapeutic member includes a single radioactive seed and is adapted to be implanted into patient tissue using a hollow needle. The seed includes a metallic housing with radioactive material contained within the metallic housing. A polymeric bio-adherent and/or bio-adhesive material surrounds at least a portion the housing of the single radioactive seed. The polymeric bio-adherent and/or bio-adhesive material reduces a tendency of the member to migrate and rotate within a patient's body after implantation of the member.
摘要翻译： 在一个实施例中，治疗构件包括单个放射性种子，并且适于使用空心针将其植入患者组织。 种子包括金属外壳，放射性材料包含在金属外壳内。 聚合物生物粘附和/或生物粘合剂材料包围单个放射性种子的壳体的至少一部分。 聚合物生物粘附和/或生物粘合剂材料降低了在植入植入物之后，患者迁移并在患者体内旋转的倾向。
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公开(公告)号：US07497818B2
公开(公告)日：2009-03-03
申请号：US10397940
申请日：2003-03-26
IPC分类号： A61N5/00
CPC分类号： A61N5/1027 , A61N5/1007 , A61N2005/1023 , A61N2005/1024 , B29C47/0009 , B29C47/021 , B29C47/028 , G21G4/08
摘要： A delivery system and method for interstitial radiation therapy comprising a substantially axially stiff and longitudinally flexible elongated member made of material, which is bio-absorbable in living tissue and a plurality of radioactive seeds dispersed in a predetermined array within the member. The delivery system and method further customize the member based on a prescription.
摘要翻译： 一种用于间质放射治疗的递送系统和方法，包括基本上轴向刚性的和纵向柔性的细长构件，其由在生物体组织中可生物吸收的材料制成，并且多个放射性种子以预定阵列分散在该构件内。 递送系统和方法基于处方进一步定制成员。
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公开(公告)号：US07407477B2
公开(公告)日：2008-08-05
申请号：US11692084
申请日：2007-03-27
申请人： Gary A. Lamoureux
发明人： Gary A. Lamoureux
IPC分类号： A61N5/00
CPC分类号： A61N5/1027 , A61N5/1007 , A61N2005/1023 , A61N2005/1024 , B29C47/0009 , B29C47/021 , B29C47/028 , G21G4/08
摘要： A treatment strand for insertion into a patient using a needle. The treatment strand includes an elongated member having first and second longitudinal ends, and a plurality of treatments seeds spaced apart from one another between the longitudinal ends. One of the longitudinal ends of the elongated member is a needle plug.
摘要翻译： 用针插入患者的治疗线。 处理线包括具有第一和第二纵向端部的细长构件和在纵向端部之间彼此间隔开的多个处理种子。 细长构件的纵向端部之一是针塞。
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公开(公告)号：US07278972B2
公开(公告)日：2007-10-09
申请号：US10347966
申请日：2003-01-21
IPC分类号： A61B10/00
CPC分类号： A61B10/025 , A61B10/0266 , A61B10/0283 , A61B2010/0225
摘要： A combined bone marrow aspiration and core biopsy device. A large bore cannula includes a coaxial stylet which seals both ends of the cannula, allowing fluid to be aspirated through the space between stylet and cannula. Then, a core sample is taken with the cannula after the stylet is retracted.
摘要翻译： 联合骨髓抽吸和核心活检装置。 大口径套管包括密封套管两端的同轴管心针，允许流体通过探针和插管之间的空间被吸入。 然后，在探针收回后，用插管取出核心样品。
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公开(公告)号：US07211039B2
公开(公告)日：2007-05-01
申请号：US11409805
申请日：2006-04-24
申请人： Gary A. Lamoureux
发明人： Gary A. Lamoureux
IPC分类号： A61N5/00
CPC分类号： A61N5/1027 , A61N5/1007 , A61N2005/1023 , A61N2005/1024 , B29C47/0009 , B29C47/021 , B29C47/028 , G21G4/08
摘要： A treatment strand for insertion into a patient using a needle. The strand includes an elongated member having first and second longitudinal ends, and a plurality of treatments seeds spaced apart from one another within the elongated member between the longitudinal ends. A needle plug is located at one of the longitudinal ends of the elongated member and integrally formed with the elongated member. The integrally formed needle plug is configured to prevent at least one of fluid and tissue from entering a needle when the elongated member is loaded into a needle and the needle is initially inserted into a patient.
摘要翻译： 用针插入患者的治疗线。 股线包括具有第一和第二纵向端部的细长构件以及在纵向端部之间在细长构件内彼此间隔开的多个处理种子。 针塞位于细长构件的一个纵向端部并与细长构件一体形成。 整体形成的针头塞构造成当细长构件装入针头并且针头最初插入到患者体内时，防止流体和组织中的至少一个进入针头。
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10.发明授权Delivery system and method for interstitial radiation therapy using seed strands with custom end spacing 失效使用具有定制末端间距的种子线进行间质放射治疗的递送系统和方法公开(公告)号：US06997862B2
公开(公告)日：2006-02-14
申请号：US10619928
申请日：2003-07-15
CPC分类号： A61M37/0069 , A61B17/3468 , A61B2017/3407 , A61B2017/3411 , A61N5/1027 , A61N2005/1012 , A61N2005/1023
摘要： A delivery system and method for interstitial radiation therapy comprising a substantially axially stiff and longitudinally flexible elongated strand made of material, which is bio-absorbable in living tissue and a plurality of radioactive seeds dispersed in a predetermined array within the strand. The delivery system and method further customize the strand based on a prescription. The strands can have custom end spacings, which allow the optimal placing of seeds within the treatment tissue by implanting a plurality of strands to the same depth. A plurality of these strands can be implanted at the same time by the use of a guiding device.
摘要翻译： 一种用于间质放射治疗的递送系统和方法，其包括在生物体组织中可生物吸收的基本上轴向刚性且纵向柔性的由细长的材料构成的细长股线，以及分散在股线内预定阵列的多个放射性种子。 递送系统和方法基于处方进一步定制链。 股线可以具有定制的端部间隔，其允许通过将多个股线植入同一深度来最佳地将种子放置在处理组织内。 可以通过使用引导装置同时植入多个这些股线。
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