摘要:
Improved transition state analog inhibitors of ricin toxin-A are provided. Methods of using those inhibitors to inhibit ricin toxin-A and to prevent the toxic effects of rich toxin-A in a mammal are also provided.
摘要:
A pulley apparatus (27) is disclosed which is adapted for use with a double hung wind. (10). The apparatus is used in pairs which are mounted in a recess (30) formed in the head (20) of the double hunt window. A pair of sash cords (25) are routed through the apparatuses and are attached to each sash so as to counterbalance one to the other, without the use of springs or extra weights.
摘要:
The present invention relates to compounds of the general formula (I) which are inhibitors of purine muclioside phosphorylases (PNP), purine phosphoribosyltransferases (PPRT), 5′-methylthioadenosine phosphorylases (MTAP), 5′-methylthioadenosine mucliosidases (MTAN) and/or nucleoside hydrolases (NH). The invention also relates to the use of these compounds in the treatment of diseases and infections including cancer, bacterial infections, protozoal infections, and T-cell mediated disease and to pharmaceutical compositions containing the compounds.
摘要:
A tracked vehicle (18), or a kit (10) for converting a standard bicycle (14) into a tracked cycle, includes a track assembly (22) with a bogie assembly (84) for riding on snow, mud, sand, etc. The track assembly includes a continuous track (60) movably disposed about a drive wheel (64) coupled to a frame (34) of the vehicle or bike, and a bogie wheel (68) disposed rearward of the drive wheel. The bogie assembly includes a compliant and resilient arm (80) coupling the bogie wheel to the frame of the vehicle or bike. The arm exerts a force against the bogie wheel, which forces the track towards the riding surface.
摘要:
A high-speed tester channel architecture is disclosed for delivering and receiving signals to and from a device-under-test. The tester channel architecture includes drive/compare circuitry having respective driver and comparator transmission line paths and backmatch resistor circuitry to establish a backmatch condition. Peaking circuitry is disposed in each of the driver and comparator transmission line paths. The peaking circuitry includes a capacitive branch and an inductive branch operative to preserve the backmatch condition.
摘要:
An improved cut plant watering apparatus for detecting and indicating a predetermined water fill level to prevent overfilling and spillage when watering a cut plant, such as a Christmas tree, mounted in a container comprising a conduit for carrying water from a fill location to the container, an indicator in communication with and responsive to a detector that, when used to fill the container with water, indicates that the predetermined water level has been reached so that a person does not inadvertently overfill the container, thereby eliminating water damage to surrounding objects or to the carpet and floor.
摘要:
A system and method for displaying a three-dimensional image of airspace includes a series of translucent, horizontal “pavers” that lie like stepping stones marking the selected flight path. In addition, the display includes a series of vertical rectangles—called “wickets”—which bracket the selected flight path. One or more of the wickets may include a graphical representation of the direction of the aircraft should be flying through the wicket. The system accommodates changes in course by generating a new flight path when instructed to do so. The new flight path is created in a way that assures continuous guidance for the pilot and sufficient time for the pilot to adjust to the new course. The display can include a compass rose which indicates the aircraft's present heading and direction of flight. The compass rose is generated from data representing a traditional two-dimensional view of a compass rose that is rotated using a graphics processor to show a three dimensional view of the compass rose in a plane that appears nearly horizontal in the three dimensional airspace image. In addition various landmarks such as airports and navigation beacons, as well as geopolitical boundaries may be included in the display.
摘要:
A single-mode grating-outcoupled surface emitting (GSE) semiconductor laser architecture is provided. This architecture enables high speed modulation of the GSE laser, which is accomplished by only varying the relative phase of counter propagating waves in the outcoupler grating region of the lasing cavity.
摘要:
Laser diodes are formed with an outcoupling grating between two separate distributed Bragg reflectors. The devices have gain regions located between the reflector gratings for pumping the active region. The outcoupling grating couples light out of the waveguide normal to the surface if the grating spacings are equal to an integer number of wavelengths of the light within the cavity. If the gratings are not such an integer number, the light is coupled out of the cavity off the normal.
摘要:
Activated carbon particles for use as iodine trapping material are impregnated with a mixture of selected iodine and potassium compounds to improve the iodine retention properties of the carbon. The I/K ratio is maintained at less than about 1 and the pH is maintained at above about 8.0. The iodine retention of activated carbon previously treated with or coimpregnated with triethylenediamine can also be improved by this technique. Suitable flame retardants can be added to raise the ignition temperature of the carbon to acceptable standards.