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公开(公告)号：US6071724A
公开(公告)日：2000-06-06
申请号：US986765
申请日：1997-12-08
IPC分类号： C07K14/315 , C12N1/21 , C12N9/12 , C12N9/24 , C12N15/10 , C12N15/31 , C12N15/74 , C12P21/04 , G01N33/569 , C12P21/06
CPC分类号： G01N33/56944 , C07K14/3156 , C12N15/1006 , C12N15/746 , C12N9/1247 , C12Y302/01018 , G01N2333/315 , Y10S435/822
摘要： The invention provides isolated nucleic acid compounds encoding Era of Streptococcus pneumoniae. Also provided are vectors and transformed host cells for expressing the encoded protein, and a method for identifying compounds that bind and/or inhibit said protein.
摘要翻译： 本发明提供编码肺炎链球菌时代的分离的核酸化合物。 还提供了用于表达编码的蛋白质的载体和转化的宿主细胞，以及用于鉴定结合和/或抑制所述蛋白质的化合物的方法。
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公开(公告)号：US6136557A
公开(公告)日：2000-10-24
申请号：US987123
申请日：1997-12-08
IPC分类号： C07K14/315 , C12N1/21 , C12N9/12 , C12N9/24 , C12N15/10 , C12N15/31 , C12N15/74 , C12P21/04 , G01N33/569 , C07H21/04 , C12N1/20 , C12N15/00 , C12N15/63
CPC分类号： G01N33/56944 , C07K14/3156 , C12N15/1006 , C12N15/746 , C12N9/1247 , C12Y302/01018 , G01N2333/315 , Y10S435/822
摘要： The invention provides isolated nucleic acid compounds encoding FtsH of Streptococcus pneumoniae. Also provided are vectors and transformed host cells for expressing the encoded protein, and a method for identifying compounds that bind and/or inhibit said protein.
摘要翻译： 本发明提供编码肺炎链球菌FtsH的分离的核酸化合物。 还提供了用于表达编码的蛋白质的载体和转化的宿主细胞，以及用于鉴定结合和/或抑制所述蛋白质的化合物的方法。
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公开(公告)号：US6074847A
公开(公告)日：2000-06-13
申请号：US986769
申请日：1997-12-08
IPC分类号： C07K14/315 , C12N1/21 , C12N9/12 , C12N9/24 , C12N15/10 , C12N15/31 , C12N15/74 , C12P21/04 , G01N33/569 , C12P21/06
CPC分类号： G01N33/56944 , C07K14/3156 , C12N15/1006 , C12N15/746 , C12N9/1247 , C12Y302/01018 , G01N2333/315 , Y10S435/822
摘要： The invention provides isolated nucleic acid compounds encoding HI1146 of Streptococcus pneumoniae. Also provided are vectors and transformed host cells for expressing the encoded protein, and a method for identifying compounds that bind and/or inhibit said protein.
摘要翻译： 本发明提供编码肺炎链球菌HI1146的分离的核酸化合物。 还提供了用于表达编码的蛋白质的载体和转化的宿主细胞，以及用于鉴定结合和/或抑制所述蛋白质的化合物的方法。
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公开(公告)号：US5958730A
公开(公告)日：1999-09-28
申请号：US986963
申请日：1997-12-08
申请人： Paul Luther Skatrud , Robert Brown Peery , Q May Wang , Paul Robert Rosteck, Jr. , Michele Louise Young Bellido
发明人： Paul Luther Skatrud , Robert Brown Peery , Q May Wang , Paul Robert Rosteck, Jr. , Michele Louise Young Bellido
IPC分类号： C07K14/315 , C12N1/21 , C12N9/12 , C12N9/24 , C12N15/10 , C12N15/31 , C12N15/74 , C12P21/04 , G01N33/569 , C12P21/06 , C12N1/20 , C12N15/00 , C07H21/044
CPC分类号： G01N33/56944 , C07K14/3156 , C12N15/1006 , C12N15/746 , C12N9/1247 , C12Y302/01018 , G01N2333/315 , Y10S435/822
摘要： The invention provides isolated nucleic acid compounds encoding FtsY of Streptococcus pneumoniae. Also provided are vectors and transformed host cells for expressing the encoded protein, and a method for identifying compounds that bind and/or inhibit said protein.
摘要翻译： 本发明提供编码肺炎链球菌FtsY的分离的核酸化合物。 还提供了用于表达编码的蛋白质的载体和转化的宿主细胞，以及用于鉴定结合和/或抑制所述蛋白质的化合物的方法。
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公开(公告)号：USH2071H1
公开(公告)日：2003-07-01
申请号：US08987147
申请日：1997-12-08
IPC分类号： C12P2104
摘要： The invention provides isolated nucleic acid compounds encoding the 454 gene of Streptococcus pneumoniae. Also provided are vectors and transformed host cells for expressing the encoded protein, and a method for identifying compounds that bind and/or inhibit said protein.
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公开(公告)号：US06271000B1
公开(公告)日：2001-08-07
申请号：US08986768
申请日：1997-12-08
IPC分类号： C12P2106
CPC分类号： G01N33/56944 , C07K14/3156 , C12N9/1247 , C12N15/1006 , C12N15/746 , C12Y302/01018 , G01N2333/315 , Y10S435/822
摘要： The invention provides isolated nucleic acid compounds encoding enzyme mraY of Streptococcus pneumoniae. Also provided are vectors and transformed host cells for expressing the encoded enzyme, and a method for identifying compounds that inhibit said enzyme.
摘要翻译： 本发明提供编码肺炎链球菌的酶mraY的分离的核酸化合物。 还提供了用于表达编码的酶的载体和转化的宿主细胞，以及用于鉴定抑制所述酶的化合物的方法。
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公开(公告)号：US06171834B2
公开(公告)日：2001-01-09
申请号：US09303272
申请日：1999-04-30
申请人： Jo Ann Hoskins , Franklin Harpold Norris , Pamela Kay Rockey , Paul Robert Rosteck, Jr. , Paul Luther Skatrud , Patti Jean Treadway , Michele Louise Young Bellido , Chyun-Yeh Earnest Wu
发明人： Jo Ann Hoskins , Franklin Harpold Norris , Pamela Kay Rockey , Paul Robert Rosteck, Jr. , Paul Luther Skatrud , Patti Jean Treadway , Michele Louise Young Bellido , Chyun-Yeh Earnest Wu
IPC分类号： C12N900
CPC分类号： C12Q1/533 , C12N9/90 , Y10S530/82 , Y10S530/825
摘要： The invention provides isolated nucleic acid compounds encoding the stem peptide biosynthetic gene murI of Streptococcus pneumoniae. Also provided are vectors and transformed heterologous host cells for expressing the MurI enzyme product and a method for identifying compounds that inhibit stem peptide biosynthesis.
摘要翻译： 本发明提供编码肺炎链球菌的干肽生物合成基因murI的分离的核酸化合物。 还提供了用于表达MurI酶产物的载体和转化的异源宿主细胞，以及用于鉴定抑制干肽生物合成的化合物的方法。
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公开(公告)号：US5948645A
公开(公告)日：1999-09-07
申请号：US759907
申请日：1996-12-04
申请人： Jo Ann Hoskins , Franklin Harpold Norris , Pamela Kay Rockey , Paul Robert Rosteck, Jr. , Paul Luther Skatrud , Patti Jean Treadway , Michele Louise Young Bellido , Chyun-Yeh Earnest Wu
发明人： Jo Ann Hoskins , Franklin Harpold Norris , Pamela Kay Rockey , Paul Robert Rosteck, Jr. , Paul Luther Skatrud , Patti Jean Treadway , Michele Louise Young Bellido , Chyun-Yeh Earnest Wu
CPC分类号： C12Q1/533 , C12N9/90 , Y10S530/82 , Y10S530/825
摘要： The invention provides isolated nucleic acid compounds encoding the stem peptide biosynthetic gene murI of Streptococcus pneumoniae. Also provided are vectors and transformed heterologous host cells for expressing the MurI enzyme product and a method for identifying compounds that inhibit stem peptide biosynthesis.
摘要翻译： 本发明提供编码肺炎链球菌的干肽生物合成基因murI的分离的核酸化合物。 还提供了用于表达MurI酶产物的载体和转化的异源宿主细胞，以及用于鉴定抑制干肽生物合成的化合物的方法。
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