-
1.发明授权Controlled release systems of pluribioactive antifungal drugs and applications thereof 有权pluribioactive抗真菌药物的控制释放系统及其应用公开(公告)号：US09006278B2
公开(公告)日：2015-04-14
申请号：US12931327
申请日：2011-01-29
IPC分类号： A01N43/50 , A61K31/415 , A61K31/497 , A61K31/496 , A61K31/4174 , A61K31/506 , A61K31/7048
CPC分类号： A61K31/7048 , A61K31/4174 , A61K31/496 , A61K31/506
摘要： Controlled release systems release at least one pluribioactive antifungal drug exhibiting at least one additional bioactivity from the group consisting of spermiostatic, antineoplastic, antibacterial, antirestenotic and antiviral activities. The drug release system is designed for use as a spermiostatic contraceptive, intravaginal ringed-mesh which may also exhibit antiviral activity, an in situ-forming implant for treating different forms of cancer and topical film for treating or preventing bacterial and fungal infections.
摘要翻译： 控制释放系统释放至少一种展现至少一种额外生物活性的多药抗真菌药物，其由精子，抗肿瘤，抗菌，抗再狭窄和抗病毒活性组成。 药物释放系统被设计用作精子避孕药，也可能表现出抗病毒活性的阴道内环网，用于治疗不同形式癌症的原位形成植入物和用于治疗或预防细菌和真菌感染的局部膜。
-
公开(公告)号：US20180303592A1
公开(公告)日：2018-10-25
申请号：US15768463
申请日：2016-11-04
申请人： Georgios T. HILAS , POLY-MED, INC.
CPC分类号： A61F2/0063 , A61F2002/0068 , A61F2240/001 , A61F2250/0031 , A61F2250/0067 , D04B21/12 , D10B2509/08
摘要： A fabric or mesh construct, and process for making same, which allows for early wound stability and then transitions to a more compliant state exhibiting a substantially constant macro-porous pore structure through the life of the implant to promote good tissue incorporation without bridging.
-
3.发明申请Hydroswellable, segmented, aliphatic polyurethane ureas and intra-articular devices therefrom 审中-公开可湿性，分段，脂肪族聚氨酯脲和其中的关节内装置公开(公告)号：US20100056646A1
公开(公告)日：2010-03-04
申请号：US12586788
申请日：2009-09-28
CPC分类号： C08G18/73 , A61L27/18 , A61L27/52 , A61L2430/06 , C08G18/12 , C08G18/4009 , C08G18/4808 , C08G18/4841 , C08G18/4854 , C08G18/61 , C08G2230/00 , C08G18/3228 , C08L75/04
摘要： Hydroswellable, non-absorbable, biostable, segmented, aliphatic polyether-urethane-ureas or polyether-siloxane-urethane-ureas form a single component, intra-articular device for restoring joints with artificial cartilage, as a cartilage substitute for degenerated cartilage and/or for enhancing the remaining cartilage of an arthritic joint. The intra-articular devices can be bicomponent in nature comprising a biostable, articulating, non-absorbable component and an absorbable component in the form of a solid or microporous liner interfacing with the tissue of defective or diseased joint to support in situ tissue engineering. One or more bioactive agent with specific pharmacological function can be incorporated in the single or bicomponent intra-articular devices to supplement their structural functions.
摘要翻译： 可渗透的，不可吸收的，生物稳定的，分段的脂族聚醚 - 氨基甲酸酯脲或聚醚 - 硅氧烷 - 氨基甲酸酯脲形成单一组分，用于用人造软骨恢复关节的关节内装置，作为退化软骨的软骨替代物和/或 用于增强关节炎关节的剩余软骨。 关节内装置本质上可以是双组分的，包括生物稳定的，关节的，不可吸收的组分和固定或微孔衬垫形式的可吸收组分，其与缺损或患病关节的组织接合以支持原位组织工程。 具有特定药理功能的一种或多种生物活性剂可并入单组分或双组分关节内装置中以补充其结构功能。
-
公开(公告)号：US20130267137A1
公开(公告)日：2013-10-10
申请号：US13445525
申请日：2012-04-12
CPC分类号： D04B21/12 , A61F2/0063 , A61F2002/0068 , A61F2210/0004 , A61F2250/0031 , D10B2401/12 , D10B2509/08 , Y10T442/184
摘要： A polymeric mesh is disclosed. The polymeric mesh comprises an absorbable polymeric fiber and a non-absorbable polymeric fiber knitted together to form an interdependent, co-knit mesh structure. Also disclosed are methods for making the polymeric mesh and methods for using the polymeric mesh.
摘要翻译： 公开了聚合物网。 聚合物网包括可吸收的聚合物纤维和不可吸收的聚合物纤维，其编织在一起以形成相互依赖的共同编织网状结构。 还公开了制备聚合物网的方法和使用聚合物网的方法。
-
公开(公告)号：US11959207B2
公开(公告)日：2024-04-16
申请号：US13445525
申请日：2012-04-12
CPC分类号： D04B21/12 , A61F2/0063 , A61F2002/0068 , A61F2210/0004 , A61F2250/0031 , D10B2401/12 , D10B2509/08 , Y10T442/184
摘要： A polymeric mesh is disclosed. The polymeric mesh comprises an absorbable polymeric fiber and a non-absorbable polymeric fiber knitted together to form an interdependent, co-knit mesh structure. Also disclosed are methods for making the polymeric mesh and methods for using the polymeric mesh.
-
公开(公告)号：US09034365B2
公开(公告)日：2015-05-19
申请号：US12448022
申请日：2009-05-11
IPC分类号： A61F6/14 , A61K31/4174 , A61K31/42 , A61F6/08
CPC分类号： A61K31/4174 , A61F6/08 , A61K9/0036 , A61K31/42 , A61L31/02 , A61L31/16 , A61L2300/404 , A61L2300/606 , A61L2420/06
摘要： Biostable, multipurpose, microbicidal intravaginal devices in the form of rings, ringed-meshes, sponges, or diaphragms for use by women and condoms for use by male partners are provided, wherein each of the devices contains a drug effective in treating a particular vaginal infection, while further exhibiting at least one additional function selected from the group dealing with non-hormonal contraception, management of sexually transmitted diseases, viral infections, and retroviral infections as well as the treatment of cervical cancer.
摘要翻译： 提供了由男性和女性使用的妇女和避孕套使用的戒指，环形网，海绵或隔膜形式的生物稳定，多用途，杀微生物的阴道内装置，其中每个装置含有有效治疗特定阴道感染的药物 同时进一步显示出选自治疗非激素避孕，性传播疾病，病毒感染和逆转录病毒感染的治疗组以及子宫颈癌治疗的组中的至少一种附加功能。
-
7.发明申请公开(公告)号：US20130144264A1
公开(公告)日：2013-06-06
申请号：US13754110
申请日：2013-01-30
CPC分类号： A61K31/7036 , A01N25/34 , A61K9/0034 , A61K9/0053 , A61K31/12 , A61K31/192 , A61K31/337 , A61K31/4025 , A61K31/4164 , A61K31/4174 , A61K31/4196 , A61K31/427 , A61K31/436 , A61K31/496 , A61K31/497 , A61K31/505 , A61K31/506 , A61K31/65 , A61K47/34 , A61M25/002 , A61M25/04 , A61M25/10 , A61M31/00 , A61M31/007 , A61M2025/0024 , A61M2025/105 , B65B3/04 , B65B51/10 , B65B55/04 , B65B55/14 , B65D65/38
摘要： Bioactive, hydroforming luminal liner compositions are formed of high molecular weight crystalline, absorbable copolyesters dissolved in a liquid derivative of a polyether glycol that undergoes transformation into a tissue-adhering, resilient interior cover or liner for the controlled release of its bioactive payload at clinically compromised conduits in humans as in the case of bacteria- and yeast-infected vaginal canals, esophagi, and arteries following angioplasty.
-
8.发明授权Absorbable crystalline polyether-ester-urethane-based bioactive luminal liner compositions 有权可吸收的结晶聚醚 - 酯 - 氨基甲酸酯基生物活性腔内衬组合物公开(公告)号：US08691235B2
公开(公告)日：2014-04-08
申请号：US12798458
申请日：2010-04-05
IPC分类号： A61K39/00 , A61K31/496 , A61K31/4164 , A61K31/506 , A61K31/4196 , A61K31/04
CPC分类号： A61K47/34 , A61K9/0034 , A61K9/0053 , A61K9/7015 , A61K31/4025 , A61K31/4164 , A61K31/4196 , A61K31/496 , A61K31/506 , A61K31/65 , A61K31/70 , A61M25/10 , A61M31/00 , A61M2025/105 , A61M2210/1475 , B65B51/10 , B65B55/14
摘要： Bioactive hydroforming luminal liner compositions are formed of an absorbable crystalline amphiphilic polyether-ester-urethane dissolved in a liquid derivative of a polyether glycol that undergoes transformation into a tissue-adhering, resilient interior cover or liner for the controlled release of its bioactive payload at clinically compromised conduits in humans as in the case of bacteria- and yeast-infected vaginal canals, esophagi, and arteries following angioplasty.
摘要翻译： 生物活性液压成型腔内衬组合物由溶解在聚醚二醇的液体衍生物中的可吸收的结晶两亲性聚醚 - 酯 - 聚氨酯形成，其经历转变成组织粘附的弹性内盖或衬垫，用于临床控制释放其生物活性有效载荷 如在细菌和酵母感染的阴道运河，食管和血管成形术后的动脉的情况下，人的受损管道。
-
公开(公告)号：US08506988B2
公开(公告)日：2013-08-13
申请号：US13272351
申请日：2011-10-13
IPC分类号： A61F6/14
CPC分类号： A61K9/0036
摘要： A process for making a multicomponent microbicidal contraceptive intravaginal ringed-mesh device that includes forming a polymeric, fibrous mesh and adjoining a reinforcing yarn about the periphery of the fibrous mesh. The process further involves forming a polymeric ring matrix, that includes at least one contraceptive agent on the reinforced fibrous mesh, thereby encasing the reinforcing yarn and the mesh periphery, and applying at least one bioactive agent to the ringed-mesh.
摘要翻译： 一种制备多组分杀微生物避孕药物阴道内环网装置的方法，包括形成聚合物纤维网，并且邻近纤维网周边的增强纱线。 该方法还包括形成聚合物环基质，其包括在增强的纤维网上的至少一种避孕剂，从而包裹增强纱线和网眼周边，以及将至少一种生物活性剂施用于环形网。
-
10.发明授权公开(公告)号：US08383140B2
公开(公告)日：2013-02-26
申请号：US12798457
申请日：2010-04-05
IPC分类号： A01N25/34
CPC分类号： A61K31/7036 , A01N25/34 , A61K9/0034 , A61K9/0053 , A61K31/12 , A61K31/192 , A61K31/337 , A61K31/4025 , A61K31/4164 , A61K31/4174 , A61K31/4196 , A61K31/427 , A61K31/436 , A61K31/496 , A61K31/497 , A61K31/505 , A61K31/506 , A61K31/65 , A61K47/34 , A61M25/002 , A61M25/04 , A61M25/10 , A61M31/00 , A61M31/007 , A61M2025/0024 , A61M2025/105 , B65B3/04 , B65B51/10 , B65B55/04 , B65B55/14 , B65D65/38
摘要： Bioactive, hydroforming luminal liner compositions are formed of high molecular weight crystalline, absorbable copolyesters dissolved in a liquid derivative of a polyether glycol that undergoes transformation into a tissue-adhering, resilient interior cover or liner for the controlled release of its bioactive payload at clinically compromised conduits in humans as in the case of bacteria- and yeast-infected vaginal canals, esophagi, and arteries following angioplasty.
-
-
-
-
-
-
-
-
-
搜索结果
16 条记录 (耗时 0.011 秒)
