公开(公告)号：US4712562A

公开(公告)日：1987-12-15

申请号：US914088

申请日：1986-10-01

申请人： Jacques J. Ohayon ,  Glen P. Williams

发明人： Jacques J. Ohayon ,  Glen P. Williams

IPC分类号： A61B5/00 ,  G06F19/00 ,  A61B5/02

CPC分类号： A61B5/0002 ,  G06F19/3418 ,  G06F19/3481 ,  G06F19/322

摘要： The invention provides a system and a method for obtaining from the patient's body information pertaining to the blood pressure and heart rate of a patient for the purpose of enabling a physician to monitor and prescribe treatment intended to maintain a patient's blood pressure within a predetermined range, for encouraging the patient to follow the treatment and for collecting information relating to the patient's blood pressure and heart rate. Signals are generated that represent the level of blood pressure and pulse rate of a patient in a form suitable for telephonic communication. The signals are transmitted to a remote central digital processor for storage and analysis. Data resulting from the analysis is submitted to the patient or physician. An off hook and ring detect circuit is provided preventing actuation of the system when telephonic access is unavailable.

摘要翻译： 本发明提供了一种系统和方法，用于从患者身体获得关于患者的血压和心率的信息，以使医师能够监测和开出旨在将患者的血压维持在预定范围内的治疗， 鼓励患者按照治疗方法和收集有关患者血压和心率的信息。 生成表示适合于电话通信的形式的患者的血压和脉率的水平的信号。 信号被传输到远程中央数字处理器进行存储和分析。 从分析得到的数据提交给患者或医师。 提供脱钩和环检测电路，防止当电话接入不可用时系统的致动。

公开(公告)号：US20130211248A1

公开(公告)日：2013-08-15

申请号：US13881072

申请日：2011-10-25

申请人： Kevin P. Cowan ,  Raymond C. Hoffman ,  Charles A. Lang ,  Mark Trocki ,  Arthur E. Uber, III ,  Joseph C. Mator ,  Edward P. Liscio ,  Bernard J. Hobi ,  L. Robert Crouthamel ,  Glen P. Williams ,  Vincent S. Rossitto ,  Jaroslaw Wlodarczyk ,  Matthew Schrauder

发明人： Kevin P. Cowan ,  Raymond C. Hoffman ,  Charles A. Lang ,  Mark Trocki ,  Arthur E. Uber, III ,  Joseph C. Mator ,  Edward P. Liscio ,  Bernard J. Hobi ,  L. Robert Crouthamel ,  Glen P. Williams ,  Vincent S. Rossitto ,  Jaroslaw Wlodarczyk ,  Matthew Schrauder

IPC分类号： A61M5/00

CPC分类号： A61M5/007 ,  A61M5/1452 ,  A61M5/148 ,  A61M5/2425 ,  A61M5/31511

摘要： A bladder syringe for a fluid delivery system includes a cylindrical body, a cap-bladder assembly, a plunger element disposed in the cylindrical body, and a mounting assembly to secure the cap-bladder assembly to the cylindrical body. The cylindrical body has a distal end and a proximal end and defines a throughbore. The cap-bladder assembly is adapted for connection to the distal end of the cylindrical body, and includes a cap body and a bladder. The cap body defines an interior cavity and a distal discharge conduit and is adapted to engage the distal end of the cylindrical body. A disc-shaped bladder is disposed within the interior cavity and typically includes a central membrane portion. The plunger element is disposed in the throughbore of the cylindrical body and is vented to enable evacuation of the space between the plunger element and the cap-bladder assembly in the cylindrical body.

摘要翻译： 用于流体输送系统的膀胱注射器包括圆柱体，囊 - 囊组件，设置在圆柱体中的柱塞元件和用于将囊 - 囊组件固定到圆柱体上的安装组件。 圆柱体具有远端和近端并限定通孔。 盖囊组件适于连接到圆柱体的远端，并且包括帽体和囊。 盖体限定内腔和远端排出导管，并适于接合圆柱体的远端。 盘状囊体设置在内腔内，通常包括中央膜部分。 柱塞元件设置在圆柱形主体的通孔中并且被排气以便能够排出柱塞元件和圆柱体中的囊 - 囊组件之间的空间。

公开(公告)号：US07273477B2

公开(公告)日：2007-09-25

申请号：US10466413

申请日：2002-01-18

申请人： Michael A. Spohn ,  James Albert Dedig ,  Glen P. Williams

发明人： Michael A. Spohn ,  James Albert Dedig ,  Glen P. Williams

IPC分类号： A61M31/00

CPC分类号： A61M5/1458 ,  A61M5/14546 ,  A61M5/14566

摘要： A syringe interface or adapter includes a first retaining member that pivots about an axis generally perpendicular to and offset from the axis of an injector piston when the syringe interface is attached to the injector. The first retaining member pivots in a rearward direction to engage a portion of the syringe flange. The syringe interface further includes a second retaining member slideably positioned within a passage in the syringe interface to slide in a direction generally perpendicular to the axis of the piston when the syringe interface is attached to the injector to engage a portion of the syringe flange. The first retaining member and the second retaining member preferably cooperate to engage the syringe flange around the entire perimeter of the syringe flange. The first retaining member is preferably biased toward an open position. The syringe interface can also include a rear portion having an attachment mechanism to attach the syringe interface to the injector.

摘要翻译： 注射器接口或适配器包括第一保持构件，当注射器接口附接到注射器时，第一保持构件围绕大致垂直于和从注射器活塞的轴线偏移的轴线枢转。 第一保持构件沿向后方向枢转以接合注射器凸缘的一部分。 注射器接口还包括第二保持构件，其可滑动地定位在注射器接口中的通道内，以便当注射器接口附接到注射器以与注射器凸缘的一部分接合时，大致垂直于活塞轴线的方向滑动。 第一保持构件和第二保持构件优选地配合以将注射器凸缘接合在注射器凸缘的整个周边周围。 第一保持构件优选地朝向打开位置偏置。 注射器接口还可以包括具有附接机构以将注射器接口附接到注射器的后部。

公开(公告)号：US5866004A

公开(公告)日：1999-02-02

申请号：US524916

申请日：1995-09-08

申请人： Raymond K. Houck ,  Douglas J. Koebler ,  Glen P. Williams ,  Kenneth J. Kato ,  Robert D. Parks ,  Paul A. Bauer, Jr.

发明人： Raymond K. Houck ,  Douglas J. Koebler ,  Glen P. Williams ,  Kenneth J. Kato ,  Robert D. Parks ,  Paul A. Bauer, Jr.

IPC分类号： B01D11/02 ,  B01D15/08 ,  G01N1/34 ,  G01N1/40 ,  G01N30/06 ,  G01N33/24 ,  B01D11/00

CPC分类号： G01N1/34 ,  B01D11/0203 ,  G01N2001/4061 ,  G01N2030/062 ,  G01N33/24 ,  Y10T436/255

摘要： A supercritical fluid extraction (SFE) system. The SFE system includes a mechanism for providing supercritical fluid for extracting analyte from a sample. The SFE system also includes an extraction vessel and a mechanism for moving the extraction vessel into fluidic communication with the SFE system so that supercritical fluid can flow through the extraction vessel and extract analyte from the sample. Preferably, the SFE system is additionally comprised of a mechanism for holding a plurality of extraction vessels and an extraction chamber assembly. In this design, the moving mechanism selectively moves an extraction vessel from the holding mechanism into the extraction chamber in fluidic communication with the SFE system. Preferably, the SFE system further includes a computer for controlling the functions of the SFE system. The computer, for instance, could automatically and sequentially control the supercritical fluid extractions of the samples within the holding mechanism. The SFE system preferably includes a mechanism for collecting analyte from the fluid with analyte. The collecting mechanism is in fluid communication with extraction chamber assembly and preferably includes a restrictor for controlling the flow of fluid with analyte to the collecting mechanism. The restrictor converts the fluid with analyte from a first supercritical pressure to a second pressure which is less than the first supercritical pressure.

摘要翻译： 超临界流体萃取（SFE）系统。 SFE系统包括提供用于从样品中提取分析物的超临界流体的机制。 SFE系统还包括提取容器和用于将提取容器移动到与SFE系统流体连通的机构，使得超临界流体可以流过提取容器并从样品中提取分析物。 优选地，SFE系统还包括用于保持多个提取容器和提取室组件的机构。 在该设计中，移动机构选择性地将提取容器从保持机构移动到与SFE系统流体连通的提取室中。 优选地，SFE系统还包括用于控制SFE系统的功能的计算机。 例如，计算机可以自动和顺序地控制保持机构内的样品的超临界流体萃取。 SFE系统优选地包括用于从具有分析物的流体收集分析物的机构。 收集机构与提取室组件流体连通，并且优选地包括限制器，用于控制具有分析物的流体与收集机构的流动。 限流器将具有分析物的流体从第一超临界压力转换为小于第一超临界压力的第二压力。

公开(公告)号：US5750029A

公开(公告)日：1998-05-12

申请号：US388274

申请日：1995-02-13

申请人： Raymond K. Houck ,  Douglas J. Koebler ,  Glen P. Williams ,  Joseph M. Levy ,  Victor G. Danielson

发明人： Raymond K. Houck ,  Douglas J. Koebler ,  Glen P. Williams ,  Joseph M. Levy ,  Victor G. Danielson

IPC分类号： B01D11/02 ,  B01D15/08 ,  G01N1/34 ,  G01N1/40 ,  G01N30/06 ,  G01N33/24 ,  B01D11/00

CPC分类号： G01N1/34 ,  B01D11/0203 ,  G01N2001/4061 ,  G01N2030/062 ,  G01N33/24

摘要： The present invention pertains to an apparatus for gathering analyte. The apparatus comprises a pumping mechanism for pumping solvent at supercritical pressure. The apparatus also comprises an extraction mechanism which receives a first sample and at least a second sample separate and distinct from the first sample and extract analyte from them essentially simultaneously. The extraction mechanism is connected to the pump mechanism to receive solvent at supercritical pressure for extracting the analyte from the samples. The apparatus additionally comprises a collection mechanism for collecting analyte from the solvent after the analyte has been extracted from the samples. The collection mechanism receives the supercritical solvent having the analyte extracted from the samples from the extraction mechanism. The present invention pertains to a method for extracting analyte. The method comprises the steps of pumping solvent at a supercritical pressure. Then there is the step of extracting analyte from N samples essentially simultaneously with the solvent at a supercritical pressure, where N is greater than or equal to two and is an integer. The N samples are separate and distinct from each other. Then there is the step of collecting the analyte of the N samples from the solvent.

公开(公告)号：US5193991A

公开(公告)日：1993-03-16

申请号：US663316

申请日：1991-03-01

申请人： Douglas J. Koebler ,  Glen P. Williams

发明人： Douglas J. Koebler ,  Glen P. Williams

IPC分类号： F04B15/08 ,  F04B53/16

CPC分类号： F04B53/166 ,  F04B15/08 ,  F05C2203/0895 ,  F05C2225/08

摘要： A pump for liquefied gases is provided having a low thermal conductivity liner provided in the inner bore of the pump cylinder. The low thermal conductivity liner prevents transmission to the pump cylinder of heat generated during the compression of the liquefied gas. The liner is preferably formed from a ceramic, such as zirconium, or from a plastic. In addition to the provision of the low thermal conductivity liner, techniques for reducing the dead volume of retained gases in the pump chamber are utilized to prevent the transmission of retained heat from the these gases to the incoming charge of liquefied gases.

公开(公告)号：US5954954A

公开(公告)日：1999-09-21

申请号：US879336

申请日：1997-06-20

申请人： Raymond K. Houck ,  Douglas J. Koebler ,  Glen P. Williams ,  Joseph M. Levy ,  Victor G. Danielson

发明人： Raymond K. Houck ,  Douglas J. Koebler ,  Glen P. Williams ,  Joseph M. Levy ,  Victor G. Danielson

IPC分类号： B01D11/02 ,  B01D15/08 ,  G01N1/34 ,  G01N1/40 ,  G01N30/06 ,  G01N33/24

CPC分类号： G01N1/34 ,  B01D11/0203 ,  G01N2001/4061 ,  G01N2030/062 ,  G01N33/24

摘要： The present invention pertains to an apparatus for gathering analyte. The apparatus comprises a pumping mechanism for pumping solvent at supercritical pressure. The apparatus also comprises an extraction mechanism which receives a first sample and at least a second sample separate and distinct from the first sample and extract analyte from them essentially simultaneously. The extraction mechanism is connected to the pump mechanism to receive solvent at supercritical pressure for extracting the analyte from the samples. The apparatus additionally comprises a collection mechanism for collecting analyte from the solvent after the analyte has been extracted from the samples. The collection mechanism receives the supercritical solvent having the analyte extracted from the samples from the extraction mechanism. The present invention pertains to a method for extracting analyte. The method comprises the steps of pumping solvent at a supercritical pressure. Then there is the step of extracting analyte from N samples essentially simultaneously with the solvent at a supercritical pressure, where N is greater than or equal to two and is an integer. The N samples are separate and distinct from each other. Then there is the step of collecting the analyte of the N samples from the solvent.

摘要翻译： 本发明涉及用于收集分析物的装置。 该装置包括用于在超临界压力下泵送溶剂的泵送机构。 该装置还包括提取机构，其接收第一样品和至少第二样品，其与第一样品分离并且不同，并且基本上同时从其中提取分析物。 提取机构连接到泵机构以在超临界压力下接收溶剂以从样品中提取分析物。 该装置另外包括用于在从样品中提取分析物之后从溶剂收集分析物的收集机构。 收集机构接收来自提取机构的样品提取的分析物的超临界溶剂。 本发明涉及提取分析物的方法。 该方法包括以超临界压力泵送溶剂的步骤。 然后，在超临界压力下，基本上与溶剂同时从N个样品中提取分析物，其中N大于或等于2，并且为整数。 N个样本是分开的并且彼此不同。 然后是从溶剂中收集N个样品的分析物的步骤。