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公开(公告)号：US20070129292A1
公开(公告)日：2007-06-07
申请号：US10551341
申请日：2004-03-29
IPC分类号： A61K38/55 , A61K31/7048
CPC分类号： A61K31/7048 , A61K38/2292 , A61K2300/00
摘要： A method for treating a human infected with Aspergillus by using thymosin alpha 1 as an immuno-stimulator in activating dendritic cells. The method is particularly useful in preventing an infection by Aspergillus in an immuno-compromised host being treated with a bone marrow transplantation.
摘要翻译： 一种通过使用胸腺素α1作为免疫刺激剂激活树突状细胞来治疗被曲霉菌感染的人的方法。 该方法特别可用于防止由用骨髓移植治疗的免疫受损宿主中的曲霉菌感染。
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2.发明申请USE OF THYMOSIN ALPHA 1 FOR THE PREPARATION OF A MEDICAMENT FOR THE PREVENTION AND TREATMENT OF ALLERGIES 审中-公开噻吗啉ALPHA 1用于制备预防和治疗过敏症的药物公开(公告)号：US20090270594A1
公开(公告)日：2009-10-29
申请号：US12447156
申请日：2007-09-27
IPC分类号： C07K14/47
CPC分类号： A61K38/2292
摘要： The invention concerns the use of thymosin alpha 1 for the preparation of a medicament for the prevention and treatment of allergies
摘要翻译： 本发明涉及胸腺素α1在制备用于预防和治疗过敏症的药物中的用途
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公开(公告)号：US20090232837A1
公开(公告)日：2009-09-17
申请号：US11722863
申请日：2005-12-29
申请人： Vito M. Fazio , Enrico Garaci , Guido Rasi , Monica Rinaldi , Paola Sinibaldi
发明人： Vito M. Fazio , Enrico Garaci , Guido Rasi , Monica Rinaldi , Paola Sinibaldi
CPC分类号： C07K14/47
摘要： The invention relates to novel, Frizzled-like, immunogenic peptides, useful for the stimulation of an immune response against various cancer types, particularly colon rectal carcinoma.
摘要翻译： 本发明涉及用于刺激针对各种癌症类型，特别是结肠直肠癌的免疫应答的新颖的卷曲状，免疫原性肽。
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公开(公告)号：US20120295840A1
公开(公告)日：2012-11-22
申请号：US13482978
申请日：2012-05-29
CPC分类号： A61K31/7048 , A61K38/2292 , A61K2300/00
摘要： A method for treating a human infected with Aspergillus by using thymosin alpha 1 as an immuno-stimulator in activating dendritic cells. The method is particularly useful in preventing an infection by Aspergillus in an immuno-compromised host being treated with a bone marrow transplantation.
摘要翻译： 一种通过使用胸腺素α1作为免疫刺激剂激活树突状细胞来治疗被曲霉菌感染的人的方法。 该方法特别可用于防止由用骨髓移植治疗的免疫受损宿主中的曲霉菌感染。
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公开(公告)号：US08207294B2
公开(公告)日：2012-06-26
申请号：US10551341
申请日：2004-03-29
CPC分类号： A61K31/7048 , A61K38/2292 , A61K2300/00
摘要： A method for treating a human infected with Aspergillus by using thymosin alpha 1 as an immuno-stimulator in activating dendritic cells. The method is particularly useful in preventing an infection by Aspergillus in an immuno-compromised host being treated with a bone marrow transplantation.
摘要翻译： 一种通过使用胸腺素α1作为免疫刺激剂激活树突状细胞来治疗被曲霉菌感染的人的方法。 该方法特别可用于防止由用骨髓移植治疗的免疫受损宿主中的曲霉菌感染。
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公开(公告)号：US09150627B2
公开(公告)日：2015-10-06
申请号：US11722863
申请日：2005-12-29
申请人： Vito M. Fazio , Enrico Garaci , Guido Rasi , Monica Rinaldi , Paola Sinibaldi
发明人： Vito M. Fazio , Enrico Garaci , Guido Rasi , Monica Rinaldi , Paola Sinibaldi
CPC分类号： C07K14/47
摘要： The invention relates to novel, Frizzled-like, immunogenic peptides, useful for the stimulation of an immune response against various cancer types, particularly colon rectal carcinoma.
摘要翻译： 本发明涉及用于刺激针对各种癌症类型，特别是结肠直肠癌的免疫应答的新颖的卷曲状，免疫原性肽。
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公开(公告)号：US08389680B2
公开(公告)日：2013-03-05
申请号：US13482978
申请日：2012-05-29
CPC分类号： A61K31/7048 , A61K38/2292 , A61K2300/00
摘要： A method for treating a human infected with Aspergillus by using thymosin alpha 1 as an immuno-stimulator in activating dendritic cells. The method is particularly useful in preventing an infection by Aspergillus in an immuno-compromised host being treated with a bone marrow transplantation.
摘要翻译： 一种通过使用胸腺素α1作为免疫刺激剂激活树突状细胞来治疗被曲霉菌感染的人的方法。 该方法特别可用于防止由用骨髓移植治疗的免疫受损宿主中的曲霉菌感染。
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8.发明申请USE OF THYMOSIN ALPHA 1 FOR THE PREPARATION OF A MEDICAMENT FOR THE PREVENTION AND TREATMENT OF AUTOIMMUNE DISEASES 审中-公开用于制备预防和治疗自身免疫性疾病的药物的THYMOSIN ALPHA 1的使用公开(公告)号：US20100004174A1
公开(公告)日：2010-01-07
申请号：US12446670
申请日：2007-09-27
CPC分类号： A61K38/2292
摘要： The invention concerns the use of thymosin alpha 1 for the preparation of a medicament for the prevention and treatment of autoimmune diseases such as multiple sclerosis, and inflammatory bowel diseases such as Crohn's disease or ulcerative colitis.
摘要翻译： 本发明涉及胸腺素α1用于制备用于预防和治疗自身免疫性疾病如多发性硬化和诸如克罗恩病或溃疡性结肠炎的炎症性肠病的药物的用途。
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公开(公告)号：US20060052297A1
公开(公告)日：2006-03-09
申请号：US10519082
申请日：2003-06-30
CPC分类号： A61K31/47 , A61K38/2292
摘要： The present invention provides a method for up-regulating tumor cell antigen expression, comprising administering to the cells an amount of thymalfasin sufficient to increase the expression of TLP relative to that of untreated tumor cells. Also provided are methods for enhancing the sensitivity of a immunodiagnostic or immunotherapeutic method, comprising pre-treating target tumor cells by administering to the cells an amount of thymalfasin sufficient to increase the expression of TLP relative to that of untreated tumor cells, followed by application of the immunodiagnostic or immunotherapeutic method. These methods are applicable to both in vivo and in vitro diagnostic methods, and to in vivo immunotherapeutic methods.
摘要翻译： 本发明提供了一种用于上调肿瘤细胞抗原表达的方法，包括向所述细胞施用足够增加TLP相对于未处理的肿瘤细胞表达的量的胸腺嘧啶。 还提供了增强免疫诊断或免疫治疗方法的灵敏度的方法，其包括通过向细胞施用足够增加TLP相对于未处理的肿瘤细胞表达的量的胸腺嘧啶来预处理靶肿瘤细胞，然后施用 免疫诊断或免疫治疗方法。 这些方法适用于体内和体外诊断方法以及体内免疫治疗方法。
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