公开(公告)号：US20090197326A1

公开(公告)日：2009-08-06

申请号：US12418983

申请日：2009-04-06

申请人： Abbas El Gamal ,  Helmy Eltoukhy ,  Khaled Salama

发明人： Abbas El Gamal ,  Helmy Eltoukhy ,  Khaled Salama

IPC分类号： C12M1/00

CPC分类号： C12Q1/66 ,  B01L3/5027 ,  B01L3/502715 ,  B01L2300/0654 ,  B01L2300/0819 ,  B01L2300/0877 ,  B01L2300/1822 ,  G01N21/253 ,  G01N21/6454

摘要： Characteristics of a chemical or biological sample are detected using an approach involving light detection. According to an example embodiment of the present invention, an assaying arrangement including a light detector is adapted to detect light from a sample, such as a biological material. A signal corresponding to the detected light is used to characterize the sample, for example, by detecting a light-related property thereof. In one implementation, the assaying arrangement includes integrated circuitry having a light detector and a programmable processor, with the light detector generating a signal corresponding to the light and sending the signal to the processor. The processor provides an output corresponding to the signal and indicative of a characteristic of the sample.

摘要翻译： 使用涉及光检测的方法检测化学或生物样品的特征。 根据本发明的示例性实施例，包括光检测器的测定装置适于检测来自诸如生物材料的样品的光。 使用与检测到的光对应的信号来表征样品，例如通过检测其与光的相关性。 在一个实现中，测定装置包括具有光检测器和可编程处理器的集成电路，光检测器产生对应于光的信号并将信号发送到处理器。 处理器提供对应于信号的输出并指示样本的特性。

公开(公告)号：US20090075838A1

公开(公告)日：2009-03-19

申请号：US12323645

申请日：2008-11-26

申请人： Abbas El Gamal ,  Helmy Eltoukhy ,  Khaled Salama

发明人： Abbas El Gamal ,  Helmy Eltoukhy ,  Khaled Salama

IPC分类号： C40B30/10 ,  G01N21/03

CPC分类号： C12Q1/66 ,  B01L3/5027 ,  B01L3/502715 ,  B01L2300/0654 ,  B01L2300/0819 ,  B01L2300/0877 ,  B01L2300/1822 ,  G01N21/253 ,  G01N21/6454

摘要： Characteristics of a chemical or biological sample are detected using an approach involving light detection. According to an example embodiment of the present invention, an assaying arrangement including a light detector is adapted to detect light from a sample, such as a biological material. A signal corresponding to the detected light is used to characterize the sample, for example, by detecting a light-related property thereof. In one implementation, the assaying arrangement includes integrated circuitry having a light detector and a programmable processor, with the light detector generating a signal corresponding to the light and sending the signal to the processor. The processor provides an output corresponding to the signal and indicative of a characteristic of the sample.

公开(公告)号：US08313904B2

公开(公告)日：2012-11-20

申请号：US12323645

申请日：2008-11-26

申请人： Abbas El Gamal ,  Helmy Eltoukhy ,  Khaled Salama

发明人： Abbas El Gamal ,  Helmy Eltoukhy ,  Khaled Salama

IPC分类号： C12Q1/68 ,  C12P19/34 ,  C12M1/00 ,  C12M1/34 ,  G01N27/00 ,  G01N1/10 ,  G01N21/00 ,  C07H21/02 ,  C07H21/04

CPC分类号： C12Q1/66 ,  B01L3/5027 ,  B01L3/502715 ,  B01L2300/0654 ,  B01L2300/0819 ,  B01L2300/0877 ,  B01L2300/1822 ,  G01N21/253 ,  G01N21/6454

摘要： Characteristics of a chemical or biological sample are detected using an approach involving light detection. According to an example embodiment of the present invention, an assaying arrangement including a light detector is adapted to detect light from a sample, such as a biological material. A signal corresponding to the detected light is used to characterize the sample, for example, by detecting a light-related property thereof. In one implementation, the assaying arrangement includes integrated circuitry having a light detector and a programmable processor, with the light detector generating a signal corresponding to the light and sending the signal to the processor. The processor provides an output corresponding to the signal and indicative of a characteristic of the sample.

摘要翻译： 使用涉及光检测的方法检测化学或生物样品的特征。 根据本发明的示例性实施例，包括光检测器的测定装置适于检测来自诸如生物材料的样品的光。 使用与检测到的光对应的信号来表征样品，例如通过检测其与光的相关性。 在一个实现中，测定装置包括具有光检测器和可编程处理器的集成电路，光检测器产生对应于光的信号并将信号发送到处理器。 处理器提供对应于信号的输出并指示样本的特性。

公开(公告)号：US09388462B1

公开(公告)日：2016-07-12

申请号：US11748266

申请日：2007-05-14

申请人： Helmy Eltoukhy

发明人： Helmy Eltoukhy

IPC分类号： C12Q1/68 ,  C12Q1/66 ,  G01N21/76

CPC分类号： C12Q1/6869 ,  C12Q1/66 ,  G01N21/76 ,  Y10T436/143333 ,  Y10T436/166666 ,  C12Q2565/301

摘要： Polymer sequencing is facilitated. According to an example embodiment of the present invention, a polymer sequencing approach is implemented using a multitude of polymer specimens for a particular polymer type is implemented. For each step in a polymer sequencing test, non-idealities are categorized using data obtained from the polymer sequencing test, and in response to the categorized non-idealities, a polymer sequence is identified for a corresponding step of the polymer sequencing test. With this approach, read lengths achieved with a particular polymer sequencing method can be improved.

摘要翻译： 促进聚合物测序。 根据本发明的示例性实施方案，使用针对特定聚合物类型的多种聚合物样品来实施聚合物测序方法。 对于聚合物测序测试中的每个步骤，使用从聚合物测序测试获得的数据对非理想性进行分类，并且响应于分类的非理想性，鉴定聚合物测序测试的相应步骤的聚合物序列。 通过这种方法，可以提高用特定聚合物测序方法实现的读取长度。

公开(公告)号：US08023113B2

公开(公告)日：2011-09-20

申请号：US12418983

申请日：2009-04-06

申请人： Abbas El Gamal ,  Helmy Eltoukhy ,  Khaled Salama

发明人： Abbas El Gamal ,  Helmy Eltoukhy ,  Khaled Salama

IPC分类号： G01N21/00

CPC分类号： C12Q1/66 ,  B01L3/5027 ,  B01L3/502715 ,  B01L2300/0654 ,  B01L2300/0819 ,  B01L2300/0877 ,  B01L2300/1822 ,  G01N21/253 ,  G01N21/6454

摘要： Characteristics of a chemical or biological sample are detected using an approach involving light detection. According to an example embodiment of the present invention, an assaying arrangement including a light detector is adapted to detect light from a sample, such as a biological material. A signal corresponding to the detected light is used to characterize the sample, for example, by detecting a light-related property thereof. In one implementation, the assaying arrangement includes integrated circuitry having a light detector and a programmable processor, with the light detector generating a signal corresponding to the light and sending the signal to the processor. The processor provides an output corresponding to the signal and indicative of a characteristic of the sample.

摘要翻译： 使用涉及光检测的方法检测化学或生物样品的特征。 根据本发明的示例性实施例，包括光检测器的测定装置适于检测来自诸如生物材料的样品的光。 使用与检测到的光对应的信号来表征样品，例如通过检测其与光的相关性。 在一个实现中，测定装置包括具有光检测器和可编程处理器的集成电路，光检测器产生对应于光的信号并将信号发送到处理器。 处理器提供对应于信号的输出并指示样本的特性。

公开(公告)号：US07595883B1

公开(公告)日：2009-09-29

申请号：US10663935

申请日：2003-09-16

申请人： Abbas El Gamal ,  Helmy Eltoukhy ,  Khaled Salama

发明人： Abbas El Gamal ,  Helmy Eltoukhy ,  Khaled Salama

IPC分类号： G01N21/00

CPC分类号： C12Q1/66 ,  B01L3/5027 ,  B01L3/502715 ,  B01L2300/0654 ,  B01L2300/0819 ,  B01L2300/0877 ,  B01L2300/1822 ,  G01N21/253 ,  G01N21/6454

摘要： Characteristics of a chemical or biological sample are detected using an approach involving light detection. According to an example embodiment of the present invention, an assaying arrangement including a light detector is adapted to detect light from a sample, such as a biological material. A signal corresponding to the detected light is used to characterize the sample, for example, by detecting a light-related property thereof. In one implementation, the assaying arrangement includes integrated circuitry having a light detector and a programmable processor, with the light detector generating a signal corresponding to the light and sending the signal to the processor. The processor provides an output corresponding to the signal and indicative of a characteristic of the sample.

摘要翻译： 使用涉及光检测的方法检测化学或生物样品的特征。 根据本发明的示例性实施例，包括光检测器的测定装置适于检测来自诸如生物材料的样品的光。 使用与检测到的光对应的信号来表征样品，例如通过检测其与光的相关性。 在一个实现中，测定装置包括具有光检测器和可编程处理器的集成电路，光检测器产生对应于光的信号并将信号发送到处理器。 处理器提供对应于信号的输出并指示样本的特性。