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公开(公告)号：US07394587B2
公开(公告)日：2008-07-01
申请号：US11046587
申请日：2005-01-28
IPC分类号： G02B13/00
CPC分类号： H01K1/32
摘要： An apparatus, including a substrate, having an internal surface where at least a portion of the internal surface has a smoothly varying curvature in three orthogonal directions. The apparatus also includes a photonic crystal disposed over and conformal to at least a portion of the internal surface having the smoothly varying curvature.
摘要翻译： 一种包括基板的装置，具有内表面，其中内表面的至少一部分在三个正交方向上具有平滑变化的曲率。 该装置还包括光子晶体，其设置在具有平滑变化的曲率的内表面的至少一部分上并保形。
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公开(公告)号：US06228405B1
公开(公告)日：2001-05-08
申请号：US08967262
申请日：1997-11-07
申请人： Belle Cromwell Walsh , Jeffrey John Kester , Kyle McLennan Taylor , Herbert Thomas Young , Michael Robert Sevenants , Joseph James Elsen , David Thomas Biedermann
发明人： Belle Cromwell Walsh , Jeffrey John Kester , Kyle McLennan Taylor , Herbert Thomas Young , Michael Robert Sevenants , Joseph James Elsen , David Thomas Biedermann
IPC分类号： A23L1217
摘要： A method for preparing frozen par-fried potato strips comprising about 38% to about 58% moisture which remain fresh tasting after storage at about 0° F. (−17.8° C.). The method comprises peeling, trimming and cutting raw potatoes into strips, blanching, and reducing the moisture content of the potato strips to not less than about 60%. The reduced moisture potato strips are then parfried in oil at a temperature of from about 270° F. (132° C.) to about 335° F. (168.3° C.) for a time sufficient to reduce the moisture content of the potato strips to about 38% to about 58% moisture. Thereafter, the parfried potato strips are frozen. The frozen par-fried potato strips are stable (i.e., free from off-flavor development) when stored at 0° F. (−17.8° C.) to about 20° F. (−6.7° C.) for at least 1 month. When cooked, the finished French fries have improved flavor over conventional oven baked fries.
摘要翻译： 制备冷冻油炸马铃薯条的方法，其包含约38％至约58％的水分，在约0°F（-17.8℃）储存后保持新鲜品尝。 该方法包括将生土豆切片，修剪和切割成条，漂白，并将马铃薯条的水分含量降低至不低于约60％。 然后将还原的水分马铃薯条在约270°F（132℃）至约335°F（168.3℃）的温度下在油中沥干足以减少马铃薯含水量的时间 剥离至约38％至约58％的水分。 此后，将冷冻的土豆条冻结。 当在0°F（-17.8℃）至约20°F（-6.7℃）下储存至少1次时，冷冻的油炸马铃薯条是稳定的（即没有异味发展） 月。 烹饪时，成品炸薯条比传统烘烤炸薯条有更好的风味。
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公开(公告)号：US06192302B1
公开(公告)日：2001-02-20
申请号：US09127133
申请日：1998-07-31
IPC分类号： G01M1500
CPC分类号： B60W50/0205 , B60W2050/021
摘要： A system and method are provided for analyzing a motor vehicle operating problem. A number of tests are provided for the selected system or component to determine the cause of the problem. One of the tests are selected, and instructions are displayed for the selected test. A result is input for the selected test and it is determined whether the result indicates the problem was experienced during the test. If the problem was not experienced and that the test did not experience a failure, the state of the faults that are detectable by the test are set to substantially “Possible Intermittent Fault”.
摘要翻译： 提供了一种用于分析机动车辆操作问题的系统和方法。 为选定的系统或组件提供了许多测试来确定问题的原因。 选择其中一个测试，并显示所选测试的说明。 结果是所选测试的输入，并确定结果是否表明测试期间遇到问题。 如果没有遇到问题，并且测试没有发生故障，则可通过测试检测到的故障状态被设置为基本上“可能的间歇性故障”。
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4.发明授权Benzimidazolylcarbamic acid esters substituted on the benzenoid nucleus by an oxy or thio substituent 失效苯并咪唑基氨基甲酸酯通过氧基或硫取代基取代在苯环上
公开(公告)号：US4287199A
公开(公告)日：1981-09-01
申请号：US83883
申请日：1979-10-11
IPC分类号： A61K31/415 , A61K31/4184 , A61P33/10 , C07D235/32 , C07D401/12 , C07D403/12 , A61K31/445
CPC分类号： C07D235/32
摘要： The invention relates to 2-benzimidazolylcarbamic acid esters, substituted on the benzenoid nucleus by an aminoalkoxy, aminoalkylthio, an aminoalkylsulphinyl or an aminoalkylsulphonyl grouping. The invention also includes methods for making the compounds of the invention, compositions containing said compounds and the use of said compounds and compositions as anthelminitic agents.
摘要翻译： 本发明涉及2-苯并咪唑基氨基甲酸酯，其通过氨基烷氧基，氨基烷硫基，氨基烷基亚磺酰基或氨基烷基磺酰基在苯类核上取代。 本发明还包括制备本发明化合物的方法，含有所述化合物的组合物以及所述化合物和组合物作为anthelminitic剂的用途。
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公开(公告)号：US4247546A
公开(公告)日：1981-01-27
申请号：US967035
申请日：1978-12-06
IPC分类号： A61K9/00 , A61K31/66 , A61K31/665 , A61K31/67 , A61K31/675 , A61P33/10 , C07F9/24 , C07F9/572 , C07F9/6539 , C07F9/6571 , C07F9/6574 , C07F9/6578 , A01N57/32 , A01N57/22
CPC分类号： C07F9/6539 , A61K31/66 , C07F9/2487 , C07F9/5727 , C07F9/657154
摘要： The invention includes phosphonylureidobenzene compounds of the general formula ##STR1## or pharmaceutically acceptable salts in whichR.sup.1 and R.sup.2 are identical or different and represent an alkyl group, orR.sup.1 and R.sup.2 together represent a dimethylene group, a trimethylene group or a tetramethylene group,X and Y are identical or different and represent an oxygen atom or a sulphur atom andR.sup.3 and R.sup.4 are identical or different and represent an alkyl group, orR.sup.3 and R.sup.4 together represent a trimethylene group or a tetramethylene group, orR.sup.3 and R.sup.4, together with the carbon atom and nitrogen atom between them, form a thiazolidine ring system, which are used medicinally as parasiticides.The compounds are particularly effective in combatting helminths in carnivores.Also included in the invention are pharmaceutical compositions containing said phosphonylureidobenzene compounds and methods for the treatment of warm-blooded animals by administering said compounds or compositions.
摘要翻译： 本发明包括通式为（I）的膦酰基脲基化合物或其中R 1和R 2相同或不同并且表示烷基的药学上可接受的盐，或者R 1和R 2一起表示二亚甲基，三亚甲基或四亚甲基 基，X和Y相同或不同，表示氧原子或硫原子，R3和R4相同或不同，表示烷基，或R3和R4一起表示三亚甲基或四亚甲基，或R 3和R 4 与它们之间的碳原子和氮原子一起形成噻唑烷环体系，它们在医药上用作杀寄生虫剂。 这些化合物特别有效地对抗食肉动物的蠕虫。 本发明还包括含有所述膦酰基脲基化合物的药物组合物和通过施用所述化合物或组合物治疗温血动物的方法。
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公开(公告)号：US4162319A
公开(公告)日：1979-07-24
申请号：US931576
申请日：1978-08-07
申请人： Jurgen Seubert , Rolf Pohlke , Herbert Thomas , Peter Andrews
发明人： Jurgen Seubert , Rolf Pohlke , Herbert Thomas , Peter Andrews
IPC分类号： C07D217/14 , A61K31/495 , C07D401/02 , C07D405/02
CPC分类号： C07D217/14
摘要： Isoquinolines of the formula ##STR1## wherein R.sup.1 is H, OH, alkyl; R.sup.2 is H, or an unsubstituted or substituted carbonyl, carbonyloxy or thiocarbonyl group; R.sup.3 is H, alkyl or hydroxy alkyl; R.sup.4 is H, alkyl or phenyl; R.sup.5 is O, H,H or H and alkyl, phenyl, halo or hydroxy; R.sup.6 and R.sup.7 are optional substituents; and R.sup.8 is H or alkyl, R.sup.2 being a thiocarbonyl or carbonyloxy group when R.sup.1 and R.sup.3 to R.sup.8 are H and X is O; and their physiologically acceptable salts, are antihelmintics, especially against cestodes and trematodes; some also possessing CNS activity, e.g., psychotropic and blood pressure regulating activity.
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7.发明授权
公开(公告)号：US4120961A
公开(公告)日：1978-10-17
申请号：US817467
申请日：1977-07-20
申请人： Jurgen Seubert , Rolf Pohlke , Herbert Thomas , Peter Andrews
发明人： Jurgen Seubert , Rolf Pohlke , Herbert Thomas , Peter Andrews
IPC分类号： C07D217/14 , A61K31/495 , C07D241/36
CPC分类号： C07D217/14
摘要： Isoquinolines of the formula ##STR1## wherein R.sup.1 is H, OH, alkyl; R.sup.2 is H, or an unsubstituted or substituted carbonyl, carbonyloxy or thiocarbonyl group; R.sup.3 is H, alkyl or hydroxy alkyl; R.sup.4 is H, alkyl or phenyl; R.sup.5 is O, H,H or H and alkyl, phenyl, halo or hydroxy; R.sup.6 and R.sup.7 are optional substituents; and R.sup.8 is H or alkyl, R.sup.2 being a thiocarbonyl or carbonyloxy group when R.sup.1 and R.sup.3 to R.sup.8 are H and X is O; and their physiologically acceptable salts, are antihelmintics, especially against cestodes and trematodes; some also possessing CNS activity, e.g., psychotropic and blood pressure regulating activity.
摘要翻译： 其中R 1是H，OH，烷基; R2是H或未取代或取代的羰基，羰基氧基或硫代羰基; R3是H，烷基或羟基烷基; R4是H，烷基或苯基; R5是O，H，H或H，烷基，苯基，卤素或羟基; R6和R7是任选的取代基; 当R 1和R 3至R 8为H且X为O时，R 8为H或烷基，R 2为硫代羰基或羰基氧基; 和它们的生理学上可接受的盐，是抗炎药，特别是针对绦虫和吸虫; 一些还具有CNS活性，例如精神病和血压调节活性。
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公开(公告)号：US4015012A
公开(公告)日：1977-03-29
申请号：US579446
申请日：1975-05-21
IPC分类号： A61K31/155 , A61K31/165
CPC分类号： A61K31/155
摘要： New 4-acylaminophenylacetamidines of the formula: ##STR1## in which R is a straight or branched chain alkoxyalkyl having 3 to 8 carbon atoms or straight or branched chain alkenyloxyalkyl having 3 to 8 carbon atoms wherein the alkoxy moiety or alkenyloxy moiety may substituted by alkoxy or phenyl, and including the non-toxic pharmacologically acceptable salts thereof. The products have utility as parasiticides.The products are obtained by either of two methods: (1) via the reaction of an N'-(4-aminophenyl)-N,N-dimethylacetamidine with an acylating agent or (2) via the reaction of a 4-acylaminoaniline with an N,N-dimethylacetamide or N,N-dimethylthioacetamide.
摘要翻译： 新的具有3-8个碳原子的直链或支链烷氧基烷基或具有3-8个碳原子的直链或支链链烯氧基烷基的4-氨基苯基乙酰胺，其中R是具有3-8个碳原子的直链或支链烷氧基烷基，其中烷氧基部分或烯氧基部分可被烷氧基取代 或苯基，并且包括其无毒的药理学上可接受的盐。 该产品具有作为杀寄生虫剂的作用。
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公开(公告)号：US3993760A
公开(公告)日：1976-11-23
申请号：US481792
申请日：1974-06-21
IPC分类号： C07D217/14 , C07D471/04 , A61K31/495
CPC分类号： C07D471/04 , C07D217/14
摘要： (-)-2-Benzoyl-4-oxo-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinoline is prepared by benzoylation of (-)-4-oxo-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinoline, or cyclization of a compound of the formula ##SPC1##Wherein X is F, Cl, Br, I or O-tosyl and which has the optical configuration of the final product, or cyclization of a compound of the formula ##SPC2## wherein Y is OH, alkoxy, F, Cl, Br or I under HY-removing reaction conditions and which has the optical configuration of the final product, which is an anthelmintic.
摘要翻译： （ - ） - 2-苯甲酰基-4-氧代-1,2,3,6,7,11b-六氢-4H-吡嗪并[2,1-a]异喹啉线是通过（ - ） - 4-氧代 -1,2,3,6,7,11b-六氢-4H-吡嗪并[2,1-a]异喹啉，或式WHEREIN X的化合物与F，Cl，Br，I或O-甲苯磺酰基和 其具有最终产物的光学构型，或在HY-去除反应条件下环化下式化合物其中Y是OH，烷氧基，F，Cl，Br或I，并且具有最终产物的光学构型，其中 是一个驱魔。
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公开(公告)号：US3993759A
公开(公告)日：1976-11-23
申请号：US449690
申请日：1974-03-11
申请人： Rolf Pohlke , Friedrich Loebich , Herbert Thomas , Jurgen Thyssen
发明人： Rolf Pohlke , Friedrich Loebich , Herbert Thomas , Jurgen Thyssen
IPC分类号： A23K1/16 , A61K31/495 , A61P33/10 , C07D471/04
CPC分类号： C07D471/04 , A23K20/116 , A61K31/495
摘要： 2-Benzoyl-4-oxo-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinoline is used as an anthelmintic against cestodes and trematodes, preferably in admixture with a pharmaceutically acceptable carrier.
摘要翻译： 2-苯甲酰基-4-氧代-1,2,3,6,7,11b-六氢-4H-吡嗪并[2,1-a]异喹啉被用作对绦虫和吸虫的驱肠虫剂，优选与药学上可接受的混合物 载体
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