公开(公告)号：US5966488A

公开(公告)日：1999-10-12

申请号：US6196

申请日：1998-01-13

申请人： Kazunori Miura ,  Seimi Sasaki ,  Ryoichi Ochiai ,  Hideo Sumiyoshi ,  Goji Nakagawa

发明人： Kazunori Miura ,  Seimi Sasaki ,  Ryoichi Ochiai ,  Hideo Sumiyoshi ,  Goji Nakagawa

IPC分类号： G02B6/38 ,  G02B6/42 ,  H04B10/00 ,  H04B10/25 ,  G02B6/36

CPC分类号： G02B6/3803 ,  G02B6/421 ,  G02B6/4224 ,  G02B6/4248 ,  G02B6/4204 ,  G02B6/423 ,  G02B6/4249

摘要： An optical module includes a mounting board, an optical element, an optical fiber having an optical axis, the optical fiber inserted in the mounting board to align the optical axis with the optical element, and a positioning mark provided to position the optical element on the mounting board. The mounting board has a groove provided in the middle of the mounting board and extending in a direction of the optical axis of the optical fiber, the groove enclosing the optical fiber when inserted. The groove has a vertical wall which is perpendicular to the direction of the optical axis and confronts a leading edge of the optical fiber when inserted. The positioning mark is located adjacent to an internal edge of the groove where the vertical wall is provided on the mounting board.

摘要翻译： 光学模块包括安装板，光学元件，具有光轴的光纤，将光纤插入安装板中以使光轴与光学元件对准，以及定位标记，用于将光学元件定位在 安装板。 安装板具有设置在安装板的中间并沿着光纤的光轴的方向延伸的槽，插入时包围光纤的槽。 凹槽具有垂直于光轴方向的垂直壁，并且在插入时面对光纤的前缘。 定位标记位于与安装板上设置垂直壁的槽的内边缘相邻的位置。

公开(公告)号：US5748822A

公开(公告)日：1998-05-05

申请号：US615158

申请日：1996-03-12

申请人： Kazunori Miura ,  Seimi Sasaki ,  Ryoichi Ochiai ,  Hideo Sumiyoshi ,  Goji Nakagawa

发明人： Kazunori Miura ,  Seimi Sasaki ,  Ryoichi Ochiai ,  Hideo Sumiyoshi ,  Goji Nakagawa

IPC分类号： G02B6/38 ,  G02B6/42 ,  H04B10/00 ,  H04B10/25 ,  G02B6/36

CPC分类号： G02B6/3803 ,  G02B6/421 ,  G02B6/4224 ,  G02B6/4248 ,  G02B6/4204 ,  G02B6/423 ,  G02B6/4249

摘要： An optical module includes a mounting board, an optical element, an optical fiber having an optical axis, the optical fiber inserted in the mounting board to align the optical axis with the optical element, and a positioning mark provided to position the optical element on the mounting board. The mounting board has a groove provided in the middle of the mounting board and extending in a direction of the optical axis of the optical fiber, the groove enclosing the optical fiber when inserted. The groove has a vertical wall which is perpendicular to the direction of the optical axis and confronts a leading edge of the optical fiber when inserted. The positioning mark is located adjacent to an internal edge of the groove where the vertical wall is provided on the mounting board.

公开(公告)号：US5736148A

公开(公告)日：1998-04-07

申请号：US438702

申请日：1995-05-11

申请人： Hideo Sumiyoshi ,  Charles H. Hoke, Jr.

发明人： Hideo Sumiyoshi ,  Charles H. Hoke, Jr.

IPC分类号： A61K39/00 ,  C07K14/18 ,  A61K39/12 ,  C12N7/04

CPC分类号： C07K14/005 ,  A61K39/00 ,  C12N2770/24122

摘要： cDNA clones containing the entire genome of Japanese encephalitis virus (JEV) were used to produce infectious, recombinant JEV particles with diverse virulence properties. Certain viruses retained the immunogenicity of JEV, but lacked the ability to cause encephalitis. The mutation associated with this loss of neurovirulence was localized to a nucleotide substitution in the codon encoding the 138th amino acid of the envelop protein, resulting in a mutation of an acidic amino acid to a basic amino acid. Attenuated viruses containing this mutation form the basis of a greatly improved, molecularly defined vaccine for the prevention of Japanese encephalitis in humans.

摘要翻译： 使用含有日本脑炎病毒（JEV）全部基因组的cDNA克隆产生具有不同毒力特性的感染性重组JEV颗粒。 某些病毒保留了JEV的免疫原性，但缺乏导致脑炎的能力。 与神经毒力丧失相关的突变被定位于编码包膜蛋白的第138位氨基酸的密码子中的核苷酸取代，导致酸性氨基酸向碱性氨基酸的突变。 含有这种突变的减毒病毒是预防人类日本脑炎的大大改进的分子定义疫苗的基础。

公开(公告)号：US4914403A

公开(公告)日：1990-04-03

申请号：US381457

申请日：1989-07-18

申请人： Yoshifumi Nakajima ,  Kazuharu Chiba ,  Hideo Sumiyoshi

发明人： Yoshifumi Nakajima ,  Kazuharu Chiba ,  Hideo Sumiyoshi

IPC分类号： H03L7/26

CPC分类号： H03L7/26

摘要： A cesium oscillator includes a cesium beam tube, and an oscillator circuit which generates an oscillation signal of a frequency to be supplied to the cesium beam tube. A frequency control circuit including a sweep circuit and a feedback loop circuit continuously varies the frequency of the oscillation signal. The frequency of the oscillation signal is continuously varied two times when the frequency of the oscillation signal is to be adjusted. A hold circuit holds the highest signal level of the resonance signal supplied from the cesium beam tube when the frequency control circuit continuously varies the frequency of the oscillation signal first. A control circuit controls the frequency control circuit so as to stop continuously varying the frequency when a signal level of the resonance signal obtained by continuously varying the frequency of the oscillation signal by the frequency control circuit for the second time becomes equal to the highest signal level held by the hold circuit.

公开(公告)号：US5063568A

公开(公告)日：1991-11-05

申请号：US474098

申请日：1990-05-04

申请人： Kazuharu Chiba ,  Yoshifumi Nakajima ,  Hideo Sumiyoshi

发明人： Kazuharu Chiba ,  Yoshifumi Nakajima ,  Hideo Sumiyoshi

IPC分类号： G02F1/37 ,  H01S5/0687 ,  H04B10/50 ,  H04B10/572

CPC分类号： H04B10/503 ,  H01S5/0687 ,  H04B10/572 ,  G02F1/37

摘要： A wavelength stabilized light source includes a laser diode which emits a laser beam of a wavelength of 1.56 .mu.m. A second-harmonic generator generates a second-harmonic light of the laser beam. The second-harmonic light enters a resonator which includes a resonance cell in which .sup.87 Rb atoms are filled. A phase-modulated microwave is irradiated on said resonator. The reasonator outputs a double resonance signal when the wavelength of the second-harmonic light is equal to a resonance wavelength of .sup.87 Rb and the frequency of the microwave is equal to a transition frequency of .sup.87 Rb. A first control circuit controls the microwave so that the frequency of the microwave is equal to the transition frequency. A second control circuit controls the laser diode so that the wavelength of the second-harmonic light is equal to the resonance wavelength of .sup.87 Rb. Thereby, the wavelength of the emitted laser beam is stabilized at 1.56 .mu.m.

公开(公告)号：US4201548A

公开(公告)日：1980-05-06

申请号：US871580

申请日：1978-01-23

申请人： Katsuki Tamaoku ,  Keishi Nakahara ,  Hideo Sumiyoshi ,  Masahiro Tachibana

发明人： Katsuki Tamaoku ,  Keishi Nakahara ,  Hideo Sumiyoshi ,  Masahiro Tachibana

IPC分类号： G01N33/49 ,  G01N21/77 ,  G01N31/22 ,  G01N33/50 ,  G01N33/52 ,  G01N33/00 ,  G01N33/16

CPC分类号： G01N33/525 ,  G01N31/22 ,  Y10T436/175383 ,  Y10T436/18

摘要： A method for detecting and determining a volatile or volatilizable substance in an aqueous solution or liquid and an apparatus employed for this method are disclosed. The volatile component, vaporized from the solution through a water repellent and gas permeable membrane, is brought into contact with a dried or partially dried transparent film-like color developing carrier which is provided adjacent to the membrane, and the determination is carried out by the degree of color-change of the carrier. The apparatus comprises a cover plate with sample holes, a membrane, a color developing carrier, and a cover plate with observation windows. The members are fitted tightly together to form a single composite layer.

摘要翻译： 公开了一种用于检测和测定水溶液或液体中的挥发性或挥发性物质的方法和用于该方法的装置。 通过防水透气膜从溶液中汽化的挥发性成分与干膜或部分干燥的透明膜状彩色显影载体接触，该透明膜状彩色显影载体邻近膜设置，并且由 载体颜色变化程度。 该装置包括具有样品孔的盖板，膜，彩色显影载体和具有观察窗的盖板。 这些构件紧紧地配合在一起以形成单一的复合层。