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公开(公告)号：US06337198B1
公开(公告)日：2002-01-08
申请号：US09604945
申请日：2000-06-27
IPC分类号： C21N1100
CPC分类号： A61L27/3839 , A61L27/56 , C08J9/26 , C08J9/28 , C08J2201/044 , C08J2201/0446 , C08J2201/046 , C08J2201/048 , C12N5/0068 , C12N2533/30
摘要： Biodegradable and biocompatible porous scaffolds characterized by a substantially continuous polymer phase, having a highly interconnected bimodal distribution of open pore sizes with rounded large pores of about 50 to about 500 microns in diameter and rounded small pores less than 20 microns in diameter, wherein the small pores are aligned in an orderly linear fashion within the walls of the large pores. Methods of preparing polymeric tissue scaffolds are also disclosed.
摘要翻译： 其特征在于具有基本上连续的聚合物相的生物可降解和生物相容的多孔支架，其具有高度相互关联的开放孔径的双峰分布，其直径为约50至约500微米的圆形大孔和直径小于20微米的圆形小孔 孔在大孔的壁内以有序的线性方式排列。 还公开了制备聚合物组织支架的方法。
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公开(公告)号：US6103255A
公开(公告)日：2000-08-15
申请号：US293118
申请日：1999-04-16
CPC分类号： A61L27/3839 , A61L27/56 , C08J9/26 , C08J9/28 , C12N5/0068 , C08J2201/044 , C08J2201/0446 , C08J2201/046 , C08J2201/048 , C12N2533/30
摘要： Biodegradable and biocompatible porous scaffolds characterized by a substantially continuous polymer phase, having a highly interconnected bimodal distribution of open pore sizes with rounded large pores of about 50 to about 500 microns in diameter and rounded small pores less than 20 microns in diameter, wherein the small pores are aligned in an orderly linear fashion within the walls of the large pores. Methods of preparing polymeric tissue scaffolds are also disclosed.
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