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    VACUUM ASSISTED BIOPSY DEVICE
    1.
    发明申请
    VACUUM ASSISTED BIOPSY DEVICE 有权
    真空辅助生物设备

    公开(公告)号：US20120078133A1

    公开(公告)日：2012-03-29

    申请号：US13243419

    申请日：2011-09-23

    申请人： Zachary R. Nicoson ,  Jacob Flagle ,  Michael E. Miller ,  Joseph L. Mark

    发明人： Zachary R. Nicoson ,  Jacob Flagle ,  Michael E. Miller ,  Joseph L. Mark

    IPC分类号： A61B10/02

    CPC分类号： A61B10/0275 ,  A61B10/0283 ,  A61B2010/0208

    摘要： A biopsy device having a stylet, an outer cannula, and a vacuum chamber is disclosed. The stylet includes a lumen with an open proximal end and a tissue receiving opening near a distal end thereof. The outer cannula is slidably disposed over the stylet and has an open distal end with a cutting edge formed thereon. The vacuum chamber is in communication with the lumen of the stylet. Actuation of the outer cannula causes a vacuum to be delivered to the tissue receiving opening through the lumen of the stylet before the outer cannula advances distally.

    摘要翻译： 公开了一种具有探针，外套管和真空室的活检装置。 探针包括具有开放近端的腔和在其远端附近的组织接收孔。 外套管可滑动地设置在通心针上方并且具有形成在其上的切割边缘的敞开的远端。 真空室与探针的内腔连通。 在外套管向远侧前进之前，外套管的致动导致真空通过探针的内腔被输送到组织接收口。

    Vacuum assisted biopsy device
    2.
    发明授权
    Vacuum assisted biopsy device 有权
    真空辅助活检装置

    公开(公告)号：US08048003B2

    公开(公告)日：2011-11-01

    申请号：US12205291

    申请日：2008-09-05

    申请人： Zachary R. Nicoson ,  Jacob Flagle ,  Michael E. Miller ,  Joseph L. Mark

    发明人： Zachary R. Nicoson ,  Jacob Flagle ,  Michael E. Miller ,  Joseph L. Mark

    IPC分类号： A61B10/02

    CPC分类号： A61B10/0275 ,  A61B10/0283 ,  A61B2010/0208

    摘要： A biopsy device is disclosed that comprises a cutting element mounted to a handpiece and a vacuum chamber. The cutting element comprises a stylet assembly and an outer cannula assembly. The stylet assembly includes a stylet that includes an open proximal end and a tissue opening at a distal end thereof. The distal end of the stylet is blunt-shaped. The tissue receiving opening is in communication with a lumen extending through the stylet. The outer cannula assembly includes an outer cannula that is slidably mounted over the stylet and has an open distal end with a cutting edge formed thereon. The vacuum chamber is in communication with the lumen of the stylet. The stylet is selectively advanced distally outwardly with respect to outer cannula to expose the tissue opening to targeted tissue. The outer cannula is selectively advanced over the tissue opening to sever tissue, while vacuum is generated in the vacuum chamber and delivered to the tissue opening through the lumen. The vacuum causes tissue to be drawn into and maintained in the tissue opening while the outer cannula severs tissue to obtain a biopsy core.

    摘要翻译： 公开了一种活检装置，其包括安装到手持件和真空室的切割元件。 切割元件包括探针组件和外套管组件。 探针组件包括探针，该探针包括开放的近端和在其远端的组织开口。 探针的远端是钝的。 组织接收口与延伸穿过通丝针的内腔连通。 外套管组件包括外套管，其可滑动地安装在通球针上方并且具有形成在其上的切削刃的敞开的远端。 真空室与探针的内腔连通。 探针相对于外套管选择性向外远端向外推进，以将组织开口暴露于目标组织。 选择性地将外套管推进到组织开口上以切断组织，同时在真空室中产生真空并通过内腔输送到组织开口。 真空使得组织被拉入并保持在组织开口中，同时外套管切断组织以获得活组织检查核心。

    METHODS OF TREATING VENOUS VALVE RELATED CONDITIONS WITH A FLOW-MODIFYING IMPLANTABLE MEDICAL DEVICE
    3.
    发明申请
    METHODS OF TREATING VENOUS VALVE RELATED CONDITIONS WITH A FLOW-MODIFYING IMPLANTABLE MEDICAL DEVICE 审中-公开
    用流动修改植入式医疗装置处理通气阀相关条件的方法

    公开(公告)号：US20080051879A1

    公开(公告)日：2008-02-28

    申请号：US11844003

    申请日：2007-08-23

    申请人： Brian Case ,  Gary Shirley ,  Ram Paul ,  Jacob Flagle

    发明人： Brian Case ,  Gary Shirley ,  Ram Paul ,  Jacob Flagle

    IPC分类号： A61F2/06

    CPC分类号： A61F2/2475 ,  A61F2/07 ,  A61F2002/068

    摘要： Implantable medical devices adapted to modify fluid flow within a body vessel are provided herein. The medical devices may include a fluid flow restricting channel configured to reduce longitudinal fluid flow in a retrograde direction or in an antegrade direction. Preferably, the medical devices are flow-modifying devices that reduce fluid flow through the medical device to a greater extent in a retrograde direction than in an antegrade direction. Methods of treatment comprising the step of implanting a flow-modifying medical device within a body vessel are also provided. Flow-modifying devices are useful, for example, in treating venous valve related conditions.

    摘要翻译： 本文提供了适于改变体内容器内的流体流动的植入式医疗装置。 医疗装置可以包括流体流动限制通道，该流体流动限制通道构造成减小沿逆行方向或顺行方向的纵向流体流动。 优选地，医疗装置是流动改变装置，其减少流体通过医疗装置的流体在逆行方向上比在顺行方向上更大程度地流动。 还提供了包括在身体容器内植入流动改变医疗装置的步骤的治疗方法。 流动改变装置例如在治疗静脉瓣相关病症中是有用的。

    Delivery system and devices for the rapid insertion of self-expanding devices
    5.
    发明申请
    Delivery system and devices for the rapid insertion of self-expanding devices 审中-公开
    交付系统和设备，用于快速插入自扩张设备

    公开(公告)号：US20060259118A1

    公开(公告)日：2006-11-16

    申请号：US11408121

    申请日：2006-04-20

    申请人： Dharmendra Pal ,  Charles Agnew ,  Jacob Flagle ,  David Lentz ,  Jeffry Melsheimer ,  Thomas Osborne ,  Fred Parker

    发明人： Dharmendra Pal ,  Charles Agnew ,  Jacob Flagle ,  David Lentz ,  Jeffry Melsheimer ,  Thomas Osborne ,  Fred Parker

    IPC分类号： A61F2/06

    CPC分类号： A61M25/0662 ,  A61F2/95 ,  A61F2002/9517 ,  A61M25/0045 ,  A61M25/005 ,  A61M25/0053

    摘要： Delivery systems for self-expanding devices are provided having a system proximal portion with a handle, an elongate middle section delivery device with an outer sheath and inner compression member, and a system distal portion including an outer guide channel member with first and second end portions defining a guide channel that slidably receives an inner guide channel member having a guide channel, the guide channels being substantially aligned. A mounting region for self-expanding devices is disposed radially between the inner and outer guide channel members. The outer guide channel member has a stepped profile from a first outer diameter to a second smaller outer diameter located near a transition region having a breech position opening for passage of a wire guide, catheter, or other medical instrument. The outer member is axially slideable relative to the inner member to deploy a self-expanding device. Methods of using and manufacturing are also provided.

    摘要翻译： 提供了一种用于自扩张装置的输送系统，其具有带手柄的系统近端部分，具有外护套和内部压缩构件的细长中间部分输送装置，以及包括具有第一和第二端部的外部引导通道构件的系统远端部分 限定了可滑动地容纳具有引导通道的内部引导通道构件的引导通道，所述引导通道基本对齐。 用于自膨胀装置的安装区域径向地设置在内引导通道构件和外引导通道构件之间。 外引导通道构件具有从第一外径到第二较小外径的阶梯轮廓，位于具有用于导线器，导管或其它医疗器械通过的后膛位置开口的过渡区域附近。 外部构件相对于内部构件可轴向滑动以展开自扩张装置。 还提供了使用和制造方法。

    Medical device delivery system
    8.
    发明申请
    Medical device delivery system 审中-公开
    医疗器械输送系统

    公开(公告)号：US20050228479A1

    公开(公告)日：2005-10-13

    申请号：US11149721

    申请日：2005-06-09

    申请人： Dusan Pavcnik ,  Brian Case ,  Christopher Dixon ,  Jacob Flagle ,  Michael Garrison ,  Andrew Hoffa ,  Ray Leonard

    发明人： Dusan Pavcnik ,  Brian Case ,  Christopher Dixon ,  Jacob Flagle ,  Michael Garrison ,  Andrew Hoffa ,  Ray Leonard

    IPC分类号： A61F2/01 ,  A61F2/06 ,  A61F2/24 ,  A61F2/84

    CPC分类号： A61F2/95 ,  A61F2/2436 ,  A61F2002/011 ,  A61F2002/9517

    摘要： A delivery system (10) for implanting a medical device (30) such as a venous valve into the vasculature of a patient. The delivery system includes a delivery catheter (11) having a device-containing portion (15) adjacent to the distal end (14) thereof, and an inner member (16) extending through the catheter and beyond the distal end thereof, to an atraumatic distal tip portion (17) forward of the catheter distal end. Delivery catheter (11) includes inner tube (122), flat wire coil (123) compression fitted therearound, and outer tube (112) mechanically connected to roughened outer surface (126) of the inner tube through the spacing of the coil. Delivery catheter (11) can be provided with a window (184) to allow fluoroscopic visualization of a stent valve within the delivery system.

    摘要翻译： 一种用于将诸如静脉瓣的医疗装置（30）植入患者脉管系统的输送系统（10）。 递送系统包括具有与其远端（14）相邻的装置容纳部分（15）的输送导管（11）和延伸穿过导管并超出其远端的内部构件（16）到无创伤 远端尖端部分（17）在导管远端的前方。 输送导管（11）包括内管（122），压缩在其周围的扁平线圈（123）和通过线圈的间隔机械地连接到内管的粗糙化的外表面（126）的外管（112）。 输送导管（11）可以设置有窗口（184），以允许支架瓣膜在输送系统内的荧光透视可视化。

    Prosthetic valve devices and methods of making such devices
    9.
    发明申请
    Prosthetic valve devices and methods of making such devices 有权
    假体瓣膜装置及其制造方法

    公开(公告)号：US20050027348A1

    公开(公告)日：2005-02-03

    申请号：US10909153

    申请日：2004-07-30

    申请人： Brian Case ,  Jacob Flagle

    发明人： Brian Case ,  Jacob Flagle

    IPC分类号： A61F2/06 ,  A61F2/24 ,  A61F2/90

    CPC分类号： A61F2/2412 ,  A61F2/2415 ,  A61F2/2418 ,  A61F2/2475 ,  A61F2220/0075

    摘要： Prosthetic valve devices for implantation in body vessels, and methods of making same, are provided. The device has a main body with first and second ends and defining a lumen, with the second end being inverted into the lumen. A valve is disposed at the second end. In multiple valve devices, valves are disposed at the first and second ends, and individually may be inverted into the lumen. The prosthetic valve devices may further include a support structure such as a stent. Methods of making a prosthetic valve device include providing a main body having first and second ends and defining a lumen, forming a valve at the second end, and inverting the second end into the lumen. Methods may further comprise forming multiple valves and may also include attaching a support structure.

    摘要翻译： 提供用于植入体内血管的假体瓣膜装置及其制造方法。 该装置具有主体，其具有第一和第二端并且限定内腔，其中第二端被倒置成内腔。 阀设置在第二端。 在多个阀装置中，阀设置在第一和第二端处，并且可以单独地倒置到内腔中。 假体瓣膜装置还可以包括诸如支架的支撑结构。 制造假体瓣膜装置的方法包括提供具有第一端和第二端并限定内腔的主体，在第二端形成阀，并将第二端翻转成内腔。 方法还可以包括形成多个阀并且还可以包括附接支撑结构。

    Device and surgical technique for foot surgery
    10.
    发明授权
    Device and surgical technique for foot surgery 有权

    公开(公告)号：US11883075B2

    公开(公告)日：2024-01-30

    申请号：US17980756

    申请日：2022-11-04

    申请人： Robby A. Amiot ,  Jacob Flagle

    发明人： Robby A. Amiot ,  Jacob Flagle

    IPC分类号： A61B17/66 ,  A61B17/84 ,  A61B17/64 ,  A61B90/90 ,  A61B17/56

    CPC分类号： A61B17/66 ,  A61B17/6466 ,  A61B17/846 ,  A61B90/90 ,  A61B2017/565

    摘要： A correction clamp assembly that permits a physician to surgically correct a bunion or similar deformity is provided. The assembly includes an elongate bridge, as well as first and second blocks slidably or rotatably connected to the elongate bridge. More specifically, first block is configured to slide along a slot formed in the elongate bridge, as well as rotate relative thereto. Additionally, the second block is configured to rotate relative to the elongate bridge. First and second pins may be configured to extend through the first and second block, and then into various pieces of bone. Once a cut is made in a portion of joint or bone, the pins can thereafter be moved towards and away from one another to position the respective pieces of bone in a desired location. Locking screws may also be provided to releasably secure the blocks relative to the bridge.