Abstract:
A method, system, and apparatus are provided for automated light microscopic for detection of proteins associated with cell proliferative disorders.
Abstract:
A prism assembly is provided. The prism assembly comprises a first prism component having a triangular cross-section along an optical path, a second prism component having a first quadrilateral cross-section along the optical path, a third prism component having a second quadrilateral cross-section along the optical path, a first dichroic interface between the first and second prism components and along the third prism component and configured to reflect a first range of wavelengths of the light, and a second dichroic interface between the first and third prism components and along the second prism component and configured to reflect a second range of wavelengths of the light.
Abstract:
A micro-display has a device chip with a transparent layer overlying one or more micro-electromechanical system devices. A transparent cover overlies the transparent layer. An index-of-refraction-matching medium is interposed between the transparent layer and the transparent cover. An index of refraction of the index-of-refraction-matching medium is substantially equal to an index of refraction of the transparent layer and the transparent cover.
Abstract:
A method and apparatus for automated cell analysis of biological specimens automatically scans at a low magnification to acquire images which are analyzed to determine candidate cell objects of interest. The low magnification images are converted from a first color space to a second color space. The color space converted image is then filtered. The candidate interest pixels are morphologically processed and compared to blob parameters to identify candidate objects of interest which correspond to cells or other structures relevant to medical diagnosis of the biological specimen. The location coordinates of the objects of interest are stored and additional images of the candidate cell objects are acquired at high magnification.
Abstract:
A prism assembly includes a first prism having a first front face, a first side face, and a first rear face, a second prism having a second front face parallel to the first rear face, a second side face, and a second rear face. The second prism is configured to direct a first component beam through the second side face. The prism assembly also includes a third prism having a third front face parallel to the second rear face, a third side face, and a third rear face. The third prism is configured to direct a second component beam through the third side face. The prism assembly also includes a fourth prism having a fourth front face parallel to the third rear face and a fourth rear face, the rear face being parallel to the first front face. The fourth rear face is configured to transmit a third component beam there through
Abstract:
An escrow system that comprises correlating confidential data defining a fixed condition or set of conditions for a release of escrow with data presented in an indefinite series of confidential presentations seeking to satisfy that condition or set of conditions. The system involves a process whereby the conditions for a release of the escrow are fixed (i.e. reduced to writing and not subject to change for a specified period of time) but are not fully disclosed to a party seeking a release of the escrow. Instead, a party seeking a release of the escrow is permitted to submit an indefinite number of confidential presentations seeking to satisfy all of those fixed conditions, both disclosed and undisclosed. The fact and contents of each such presentation are treated as confidential unless the presentation results in a determination by the System that all of the fixed conditions have been satisfied.
Abstract:
A light modulator assembly includes first, second, and third light modulators, with first and second dichroic mirrors. The first dichroic mirror is located at an optical pupil of said assembly and is configured to split a beam of light into a first component beam and an intermediate beam. The first dichroic mirror then transmits the first component beam to the first light modulator and reflects the intermediate beam to the second dichroic mirror. The second dichroic mirror is configured to split the intermediate beam into second and third component beams and to direct the second component beam to the second modulator and the third component beam to the third modulator. A third dichroic mirror is configured to receive the output of the first, second, and third modulators and to pass the output from the first, second, and third modulators to display optics.
Abstract:
A prism assembly is provided. The prism assembly comprises a first prism component having a triangular cross-section along an optical path, a second prism component having a first quadrilateral cross-section along the optical path, a third prism component having a second quadrilateral cross-section along the optical path, a fourth prism component having a pentagon cross-section along the optical path, a first dichroic interface between the first and second prism components and between the third and fourth prism components and configured to reflect a first range of wavelengths of the light, and a second dichroic interface between the first and third prism components and between the second and fourth prism components and configured to reflect a second range of wavelengths of the light.
Abstract:
A method and apparatus for automated cell analysis of biological specimens automatically scans at a low magnification to acquire images which are analyzed to determine candidate cell objects of interest. The low magnification images are converted from a first color space to a second color space. The color space converted image is then low pass filtered and compared to a threshold to remove artifacts and background objects from the candidate object of interest pixels of the color converted image. The candidate object of interest pixels are morphologically processed to group candidate object of interest pixels together into groups which are compared to blob parameters to identify candidate objects of interest which correspond to cells or other structures relevant to medical diagnosis of the biological specimen. The location coordinates of the objects of interest are stored and additional images of the candidate cell objects are acquired at high magnification. The high magnification images are analyzed in the same manner as the low magnification images to confirm the candidate objects of interest which are objects of interest. A high magnification image of each confirmed object of interest is stored for later review and evaluation by a pathologist.