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公开(公告)号:US09952176B2
公开(公告)日:2018-04-24
申请号:US14123897
申请日:2012-06-15
IPC分类号: G01N27/447
CPC分类号: G01N27/44721 , G01N27/44739
摘要: Apparatus and methods for size selecting nucleic acid molecules having wide range of applications including the production of DNA libraries for sequencing technologies. An automated high throughput system for size selection of multiple nucleic acid samples that uses imaging technique to detect the progress of a target fraction and feedback from the imaging to control electrophoresis. Predictive algorithms for timed nucleic acid extractions are generated to provide size selected nucleic acid molecules of required size ranges.
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公开(公告)号:US20140202859A1
公开(公告)日:2014-07-24
申请号:US14123897
申请日:2012-06-15
IPC分类号: G01N27/447
CPC分类号: G01N27/44721 , G01N27/44739
摘要: Apparatus and methods for size selecting nucleic acid molecules having wide range of applications including the production of DNA libraries for sequencing technologies. An automated high throughput system for size selection of multiple nucleic acid samples that uses imaging technique to detect the progress of a target fraction and feedback from the imaging to control electrophoresis. Predictive algorithms for timed nucleic acid extractions are generated to provide size selected nucleic acid molecules of required size ranges.
摘要翻译: 用于大小选择具有广泛应用范围的核酸分子的装置和方法,包括生产用于测序技术的DNA文库。 用于大量选择多个核酸样品的自动化高通量系统,其使用成像技术来检测目标级分的进展和从成像到对照电泳的反馈。 产生用于定时核酸提取的预测算法以提供所需尺寸范围的尺寸选择的核酸分子。
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公开(公告)号:US07955865B2
公开(公告)日:2011-06-07
申请号:US11570232
申请日:2005-06-09
申请人: Andrea Marziali , Diponkar Banerjee , Jason Donald Thompson , Kurtis Dan Guggenheimer , Jared Raymond Slobodan , Roy Alexander Belak , David Keddie Brown
发明人: Andrea Marziali , Diponkar Banerjee , Jason Donald Thompson , Kurtis Dan Guggenheimer , Jared Raymond Slobodan , Roy Alexander Belak , David Keddie Brown
IPC分类号: B01L3/02
CPC分类号: B01L3/0244 , B01J19/0046 , B01J2219/00378 , B01J2219/00387 , B01J2219/00527 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/00612 , B01J2219/00619 , B01J2219/00659 , B01J2219/00689 , B01J2219/00722 , B01J2219/00743 , B01L3/0255 , B01L2200/143 , B01L2300/0645 , B01L2300/161 , B01L2400/025 , G01N35/1011 , G01N2035/1037 , Y10T436/2575
摘要: Apparatus for dispensing droplets of reagent onto samples includes a probe tip to which droplets of reagent can adhere. The apparatus advances the probe tip toward a sample until a droplet of reagent touches the sample and is pulled off from the probe tip. A sensor detects that the droplet has been pulled off from the probe tip and halts the advance of the probe tip before the probe tip touches the sample. Such apparatus may be used to automatically dispense small volumes of reagent onto fragile samples.
摘要翻译: 用于将试剂液滴分配到样品上的装置包括试剂小滴可附着的探针尖端。 该装置将探针尖端朝向样品前进,直到试剂液滴接触样品并从探针尖端拉出。 传感器检测到液滴已经从探针尖端拔出,并且在探针尖端接触样品之前停止探针尖端的前进。 这种装置可以用于将小体积的试剂自动分配到易碎样品上。
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公开(公告)号:US20080047368A1
公开(公告)日:2008-02-28
申请号:US11570232
申请日:2005-06-09
申请人: Andrea Marziali , Diponkar Banerjee , Jason Donald Thompson , Kurtis Dan Guggenheimer , Jared Raymond Slobodan , Roy Alexander Belak , David Keddie Brown
发明人: Andrea Marziali , Diponkar Banerjee , Jason Donald Thompson , Kurtis Dan Guggenheimer , Jared Raymond Slobodan , Roy Alexander Belak , David Keddie Brown
CPC分类号: B01L3/0244 , B01J19/0046 , B01J2219/00378 , B01J2219/00387 , B01J2219/00527 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/00612 , B01J2219/00619 , B01J2219/00659 , B01J2219/00689 , B01J2219/00722 , B01J2219/00743 , B01L3/0255 , B01L2200/143 , B01L2300/0645 , B01L2300/161 , B01L2400/025 , G01N35/1011 , G01N2035/1037 , Y10T436/2575
摘要: Apparatus for dispensing droplets of reagent onto samples includes a probe tip to which droplets of reagent can adhere. The apparatus advances the probe tip toward a sample until a droplet of reagent touches the sample and is pulled off from the probe tip. A sensor detects that the droplet has been pulled off from the probe tip and halts the advance of the probe tip before the probe tip touches the sample. Such apparatus may be used to automatically dispense small volumes of reagent onto fragile samples.
摘要翻译: 用于将试剂液滴分配到样品上的装置包括试剂小滴可附着的探针尖端。 该装置将探针尖端朝向样品前进,直到试剂液滴接触样品并从探针尖端拉出。 传感器检测到液滴已经从探针尖端拔出,并且在探针尖端接触样品之前停止探针尖端的前进。 这种装置可以用于将小体积的试剂自动分配到易碎样品上。
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