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公开(公告)号：US08975082B2
公开(公告)日：2015-03-10
申请号：US13429052
申请日：2012-03-23
CPC分类号： C07K16/00 , C07K5/0819
摘要： Compositions comprising a tripeptide having the sequence XC1C2; wherein X is any amino acid such that XC1C2 is capable of binding a metal in a square planar orientation or square pyramidal orientation or both; and wherein C1 and C2 are the same or different; and wherein C1 and C2 individually are chosen from a cysteine and a cysteine-like nonnatural amino acid, as well as metal-XC1C2 complexes and methods for forming such complexes.
摘要翻译： 包含具有序列XC1C2的三肽的组合物; 其中X是任何氨基酸，使得XC1C2能够以正方形平面取向或正方形金字塔形取向或两者结合金属; 并且其中C1和C2相同或不同; 并且其中C1和C2分别选自半胱氨酸和半胱氨酸类非天然氨基酸，以及金属-XC1C2复合物和形成这种复合物的方法。
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公开(公告)号：US20130018172A1
公开(公告)日：2013-01-17
申请号：US13350247
申请日：2012-01-13
CPC分类号： A61K38/06 , C07K5/0806 , C07K5/0819 , C07K2319/20
摘要： Compositions comprising certain tripeptides which are capable of binding a metal in a square planar orientation, a square pyramidal orientation, or both, are disclosed in processes for modulating tagged peptides or proteins. Such compositions and processes may be used for site-specific chiral inversion of amino acids, site-specific peptide cleavage, and protein purification, among other uses.
摘要翻译： 在调节标记的肽或蛋白质的方法中公开了包含能够结合正方形平面取向的金属，正方形金字塔取向或两者的某些三肽的组合物。 这些组合物和方法可用于氨基酸的位点特异性手性翻转，位点特异性肽切割和蛋白质纯化以及其它用途。
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公开(公告)号：US08278111B2
公开(公告)日：2012-10-02
申请号：US13341223
申请日：2011-12-30
IPC分类号： G01N33/20
CPC分类号： C07K16/00 , C07K5/0819
摘要： Compositions comprising a tripeptide having the sequence XC1C2; wherein X is any amino acid such that XC1C2 is capable of binding a metal in a square planar orientation or square pyramidal orientation or both; and wherein C1 and C2 are the same or different; and wherein C1 and C2 individually are chosen from a cysteine and a cysteine-like nonnatural amino acid, as well as metal-XC1C2 complexes and methods for forming such complexes.
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公开(公告)号：US20120177579A1
公开(公告)日：2012-07-12
申请号：US13341223
申请日：2011-12-30
IPC分类号： A61K38/06 , A61K38/18 , A61K38/14 , A61P35/00 , A61K49/04 , A61K49/22 , A61K49/00 , A61K39/44 , A61K49/06
CPC分类号： C07K16/00 , C07K5/0819
摘要： Compositions comprising a tripeptide having the sequence XC1C2; wherein X is any amino acid such that XC1C2 is capable of binding a metal in a square planar orientation or square pyramidal orientation or both; and wherein C1 and C2 are the same or different; and wherein C1 and C2 individually are chosen from a cysteine and a cysteine-like nonnatural amino acid, as well as metal-XC1C2 complexes and methods for forming such complexes.
摘要翻译： 包含具有序列XC1C2的三肽的组合物; 其中X是任何氨基酸，使得XC1C2能够以正方形平面取向或正方形金字塔形取向或两者结合金属; 并且其中C1和C2相同或不同; 并且其中C1和C2分别选自半胱氨酸和半胱氨酸类非天然氨基酸，以及金属-XC1C2复合物和形成这种复合物的方法。
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公开(公告)号：US08110402B2
公开(公告)日：2012-02-07
申请号：US12465448
申请日：2009-05-13
CPC分类号： C07K16/00 , C07K5/0819
摘要： Compositions comprising a tripeptide having the sequence XC1C2; wherein X is any amino acid such that XC1C2 is capable of binding a metal in a square planar orientation or square pyramidal orientation or both; and wherein C1 and C2 are the same or different; and wherein C1 and C2 individually are chosen from a cysteine and a cysteine-like nonnatural amino acid, as well as metal-XC1C2 complexes and methods for forming such complexes.
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公开(公告)号：US09096652B2
公开(公告)日：2015-08-04
申请号：US13596281
申请日：2012-08-28
IPC分类号： C07K4/00 , C07K2/00 , C07K19/00 , C07K5/00 , C07K5/097 , C07K16/00 , C07K5/093 , G01N31/22 , G01N33/20 , G01N21/78 , G01N33/84 , A61K38/00
CPC分类号： C07K16/00 , C07K5/0819
摘要： Compositions comprising a tripeptide having the sequence XC1C2; wherein X is any amino acid such that XC1C2 is capable of binding a metal in a square planar orientation or square pyramidal orientation or both; and wherein C1 and C2 are the same or different; and wherein C1 and C2 individually are chosen from a cysteine and a cysteine-like nonnatural amino acid, as well as metal-XC1C2 complexes and methods for forming such complexes.
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公开(公告)号：US08252595B2
公开(公告)日：2012-08-28
申请号：US13429167
申请日：2012-03-23
IPC分类号： G01N33/00
CPC分类号： C07K16/00 , C07K5/0819
摘要： Compositions comprising a tripeptide having the sequence XC1C2; wherein X is any amino acid such that XC1C2 is capable of binding a metal in a square planar orientation or square pyramidal orientation or both; and wherein C1 and C2 are the same or different; and wherein C1 and C2 individually are chosen from a cysteine and a cysteine-like nonnatural amino acid, as well as metal-XC1C2 complexes and methods for forming such complexes.
摘要翻译： 包含具有序列XC1C2的三肽的组合物; 其中X是任何氨基酸，使得XC1C2能够以正方形平面取向或正方形金字塔形取向或两者结合金属; 并且其中C1和C2相同或不同; 并且其中C1和C2分别选自半胱氨酸和半胱氨酸类非天然氨基酸，以及金属-XC1C2复合物和形成这种复合物的方法。
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公开(公告)号：US20120177580A1
公开(公告)日：2012-07-12
申请号：US13429167
申请日：2012-03-23
IPC分类号： A61K38/06 , C07K19/00 , C07K14/475 , A61K49/04 , A61P35/00 , A61K49/14 , A61K49/00 , A61K49/22 , C07K5/08 , A61K49/16
CPC分类号： C07K16/00 , C07K5/0819
摘要： Compositions comprising a tripeptide having the sequence XC1C2; wherein X is any amino acid such that XC1C2 is capable of binding a metal in a square planar orientation or square pyramidal orientation or both; and wherein C1 and C2 are the same or different; and wherein C1 and C2 individually are chosen from a cysteine and a cysteine-like nonnatural amino acid, as well as metal-XC1C2 complexes and methods for forming such complexes.
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公开(公告)号：US20120329987A1
公开(公告)日：2012-12-27
申请号：US13596281
申请日：2012-08-28
CPC分类号： C07K16/00 , C07K5/0819
摘要： Compositions comprising a tripeptide having the sequence XC1C2; wherein X is any amino acid such that XC1C2 is capable of binding a metal in a square planar orientation or square pyramidal orientation or both; and wherein C1 and C2 are the same or different; and wherein C1 and C2 individually are chosen from a cysteine and a cysteine-like nonnatural amino acid, as well as metal-XC1C2 complexes and methods for forming such complexes.
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公开(公告)号：US20120174712A1
公开(公告)日：2012-07-12
申请号：US13429052
申请日：2012-03-23
CPC分类号： C07K16/00 , C07K5/0819
摘要： Compositions comprising a tripeptide having the sequence XC1C2; wherein X is any amino acid such that XC1C2 is capable of binding a metal in a square planar orientation or square pyramidal orientation or both; and wherein C1 and C2 are the same or different; and wherein C1 and C2 individually are chosen from a cysteine and a cysteine-like nonnatural amino acid, as well as metal-XC1C2 complexes and methods for forming such complexes.
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