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公开(公告)号:US6165470A
公开(公告)日:2000-12-26
申请号:US4319
申请日:1998-01-08
申请人: Jerome Becquart , Reinhard Fleer , Philippe Hirel , David Klatzmann , Didier Landais , Jean-Fran.cedilla.ois Mayaux , Patrice Yeh
发明人: Jerome Becquart , Reinhard Fleer , Philippe Hirel , David Klatzmann , Didier Landais , Jean-Fran.cedilla.ois Mayaux , Patrice Yeh
IPC分类号: C12N15/09 , A61K38/00 , A61K39/00 , A61K39/12 , A61K39/21 , A61P31/12 , A61P31/18 , A61P35/00 , C07K14/00 , C07K14/47 , C07K14/705 , C07K14/73 , C07K14/765 , C07K14/82 , C07K19/00 , C12N1/19 , C12N15/12 , C12N15/14 , C12N15/62 , C12N15/67 , C12N15/81 , C12P21/00 , C12P21/04 , C12R1/645
CPC分类号: C07K14/765 , A61K38/00 , C07K14/00 , C07K14/4716 , C07K14/70514 , C07K14/82 , C07K2319/00 , C07K2319/02 , C07K2319/31 , C07K2319/32 , C07K2319/73 , C12N15/62 , C12N15/67 , C12N15/815
摘要: Utilization of albumin as a stable plasma transporter with a therapeutic function that is derived from a membrane receptor. The present invention is exemplified by the description of new therapeutic agents that can be used in the treatment of Acquired Immunodeficiency Syndrome: hybrid macromolecules composed of albumin derivatives coupled to derivatives of the CD4 receptor having a normal or a higher affinity for the HIV-1 virus.
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公开(公告)号:US20050048471A1
公开(公告)日:2005-03-03
申请号:US10794774
申请日:2004-03-08
申请人: Jerome Becquart , Reinhard Fleer , Philippe Hirel , David Klatzmann , Didier Landais , Jean-Francois Mayaux , Patrice Yeh
发明人: Jerome Becquart , Reinhard Fleer , Philippe Hirel , David Klatzmann , Didier Landais , Jean-Francois Mayaux , Patrice Yeh
IPC分类号: C12N15/09 , A61K38/00 , A61K39/00 , A61K39/12 , A61K39/21 , A61P31/12 , A61P31/18 , A61P35/00 , C07K14/00 , C07K14/47 , C07K14/705 , C07K14/73 , C07K14/765 , C07K14/82 , C07K19/00 , C12N1/19 , C12N15/12 , C12N15/14 , C12N15/62 , C12N15/67 , C12N15/81 , C12P21/00 , C12P21/04 , C12R1/645 , C12Q1/70 , C07H21/04 , C07K14/74 , C12N15/86 , C12Q1/68
CPC分类号: C07K14/765 , A61K38/00 , C07K14/00 , C07K14/4716 , C07K14/70514 , C07K14/82 , C07K2319/00 , C07K2319/02 , C07K2319/31 , C07K2319/32 , C07K2319/73 , C12N15/62 , C12N15/67 , C12N15/815
摘要: Utilization of albumin as a stable plasma transporter with a therapeutic function that is derived from a membrane receptor. The present invention is exemplified by the description of new therapeutic agents that can be used in the treatment of Acquired Immunodeficiency Syndrome: hybrid macromolecules composed of albumin derivatives coupled to derivatives of the CD4 receptor having a normal or a higher affinity for the HIV-1 virus.
摘要翻译: 利用白蛋白作为具有衍生自膜受体的治疗功能的稳定血浆转运蛋白。 本发明通过描述可用于治疗获得性免疫缺陷综合征的新的治疗剂的例子:由与HIV-1病毒具有正常或更高亲和力的CD4受体的衍生物偶联的白蛋白衍生物组成的杂合大分子 。
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