公开(公告)号：US07897033B2

公开(公告)日：2011-03-01

申请号：US11481086

申请日：2006-07-05

Applicant: Byeong-woo Bae ,  Sung-dong Lee ,  Hong-seong Suk ,  Jin-a Yoo

Inventor： Byeong-woo Bae ,  Sung-dong Lee ,  Hong-seong Suk ,  Jin-a Yoo

IPC: G01N27/26 ,  G01N27/327

CPC classification number: C12Q1/006 ,  G01N27/3272

Abstract: Disclosed is a method of measuring sample reaction results on a biosensor having a working electrode and other electrodes, including: applying voltage between the working electrode and each of the other electrodes and detecting the amount of current flowing through the working electrode to determine whether or not a sample is injected; applying voltage between the working electrode and one of the other electrodes and re-detecting the amount of current flowing through the working electrode; and acquiring and displaying a concentration value as a sample reaction result corresponding to the amount of detected current.

Abstract translation: 公开了一种在具有工作电极和其他电极的生物传感器上测量样品反应结果的方法，包括：在工作电极和每个其他电极之间施加电压并检测流过工作电极的电流量，以确定是否 注入样品; 在工作电极和其他电极之间施加电压，并重新检测流过工作电极的电流量; 并且获取和显示浓度值作为与检测到的电流量对应的样品反应结果。

公开(公告)号：US20100243481A1

公开(公告)日：2010-09-30

申请号：US11481086

申请日：2006-07-05

Applicant: Byeong-woo Bae ,  Sung-dong Lee ,  Hong-seong Suk ,  Jin-a Yoo

Inventor： Byeong-woo Bae ,  Sung-dong Lee ,  Hong-seong Suk ,  Jin-a Yoo

IPC: G01N27/26

CPC classification number: C12Q1/006 ,  G01N27/3272

Abstract: Disclosed is a method of measuring sample reaction results on a biosensor having a working electrode and other electrodes, including: applying voltage between the working electrode and each of the other electrodes and detecting the amount of current flowing through the working electrode to determine whether or not a sample is injected; applying voltage between the working electrode and one of the other electrodes and re-detecting the amount of current flowing through the working electrode; and acquiring and displaying a concentration value as a sample reaction result corresponding to the amount of detected current.

Abstract translation: 公开了一种在具有工作电极和其他电极的生物传感器上测量样品反应结果的方法，包括：在工作电极和每个其他电极之间施加电压并检测流过工作电极的电流量，以确定是否 注入样品; 在工作电极和其他电极之间施加电压，并重新检测流过工作电极的电流量; 并且获取和显示浓度值作为与检测到的电流量对应的样品反应结果。

公开(公告)号：US07678261B2

公开(公告)日：2010-03-16

申请号：US10528187

申请日：2002-10-04

Applicant: Byung Woo Bae ,  Heon-Kwon Lee ,  Sung Dong Lee ,  Won Dong Kim ,  Jung Shik Song ,  Jin-A Yoo

Inventor： Byung Woo Bae ,  Heon-Kwon Lee ,  Sung Dong Lee ,  Won Dong Kim ,  Jung Shik Song ,  Jin-A Yoo

IPC: G01N33/50 ,  G01N27/327 ,  C12Q1/54 ,  C12Q1/26

CPC classification number: G01N27/3274 ,  G01N27/3273

Abstract: Disclosed are an apparatus and a method for determining whether or not a biosensor comprising two working electrodes and one reference electrode is well manufactured, and for rapidly and accurately quantifying a specific substance contained in a biological sample. The method comprises the steps of: sequentially supplying the respective working electrodes with power supply voltage; sequentially detecting the amounts of current flowing in the respective working electrodes by virtue of the supplied power supply voltage; re-supplying the two working electrodes with power supply voltage after a predetermined time to redetect the amounts of current flowing in the respective working electrodes; reading concentrations corresponding to the amounts of current detected from a memory, and calculating an average value from the read concentrations; and checking whether or not the concentrations read from memory are within a predetermined critical range to display an error message or the calculated average value.

Abstract translation: 公开了一种用于确定包括两个工作电极和一个参比电极的生物传感器是否良好制造的装置和方法，并且用于快速和准确地定量生物样品中包含的特定物质。 该方法包括以下步骤：向相应的工作电极依次提供电源电压; 通过提供的电源电压依次检测在各个工作电极中流动的电流量; 在预定时间之后将两个工作电极重新供应电源电压以重新检测在各个工作电极中流动的电流量; 读取与存储器检测到的电流量相对应的浓度，并根据读取的浓度计算平均值; 并且检查从存储器读取的浓度是否在预定的临界范围内，以显示错误消息或所计算的平均值。

公开(公告)号：US20060163086A1

公开(公告)日：2006-07-27

申请号：US10528187

申请日：2002-10-04

Applicant: Byung-Woo Bae ,  Heon-Kwon Lee ,  Sung-Dong Lee ,  Won-Dong Kim ,  Jung-Shik Song ,  Jin-A Yoo

Inventor： Byung-Woo Bae ,  Heon-Kwon Lee ,  Sung-Dong Lee ,  Won-Dong Kim ,  Jung-Shik Song ,  Jin-A Yoo

IPC: C25C3/02 ,  G01N33/487 ,  G01N27/26

CPC classification number: G01N27/3274 ,  G01N27/3273

Abstract: Disclosed are an apparatus and a method for determining whether or not a biosensor comprising two working electrodes and one reference electrode is well manufactured, and for rapidly and accurately quantifying a specific substance contained in a biological sample. The method comprises the steps of: sequentially supplying the respective working electrodes with power supply voltage; sequentially detecting the amounts of current flowing in the respective working electrodes by virtue of the supplied power supply voltage; re-supplying the two working electrodes with power supply voltage after a predetermined time to redetect the amounts of current flowing in the respective working electrodes; reading concentrations corresponding to the amounts of current detected from a memory, and calculating an average value from the read concentrations; and checking whether or not the concentrations read from memory are within a predetermined critical range to display an error message or the calculated average value.

Abstract translation: 公开了一种用于确定包括两个工作电极和一个参比电极的生物传感器是否被良好地制造并且用于快速和准确地定量生物样品中包含的特定物质的装置和方法。 该方法包括以下步骤：向相应的工作电极依次提供电源电压; 通过提供的电源电压依次检测在各个工作电极中流动的电流量; 在预定时间之后将两个工作电极重新供给电源电压以重新检测在各个工作电极中流动的电流量; 读取与存储器检测到的电流量相对应的浓度，并根据读取的浓度计算平均值; 并且检查从存储器读取的浓度是否在预定的临界范围内，以显示错误消息或所计算的平均值。

公开(公告)号：US08702923B2

公开(公告)日：2014-04-22

申请号：US13010098

申请日：2011-01-20

Applicant: Byeong-woo Bae ,  Sung-dong Lee ,  Hong-seong Suk ,  Jin-a Yoo

Inventor： Byeong-woo Bae ,  Sung-dong Lee ,  Hong-seong Suk ,  Jin-a Yoo

IPC: G01N27/26 ,  G01N27/327

CPC classification number: C12Q1/006 ,  G01N27/3272

Abstract: Disclosed is a method of measuring sample reaction results on a biosensor having a working electrode and other electrodes, including: applying voltage between the working electrode and each of the other electrodes and detecting the amount of current flowing through the working electrode to determine whether or not a sample is injected; applying voltage between the working electrode and one of the other electrodes and re-detecting the amount of current flowing through the working electrode; and acquiring and displaying a concentration value as a sample reaction result corresponding to the amount of detected current.

Abstract translation: 公开了一种在具有工作电极和其他电极的生物传感器上测量样品反应结果的方法，包括：在工作电极和每个其他电极之间施加电压并检测流过工作电极的电流量，以确定是否 注入样品; 在工作电极和其他电极之间施加电压，并重新检测流过工作电极的电流量; 并且获取和显示浓度值作为与检测到的电流量对应的样品反应结果。

公开(公告)号：US20120043201A1

公开(公告)日：2012-02-23

申请号：US13010098

申请日：2011-01-20

Applicant: Byeong-woo BAE ,  Sung-dong LEE ,  Hong-seong SUK ,  Jin-a YOO

Inventor： Byeong-woo BAE ,  Sung-dong LEE ,  Hong-seong SUK ,  Jin-a YOO

IPC: G01N27/416

CPC classification number: C12Q1/006 ,  G01N27/3272

Abstract: Disclosed is a method of measuring sample reaction results on a biosensor having a working electrode and other electrodes, including: applying voltage between the working electrode and each of the other electrodes and detecting the amount of current flowing through the working electrode to determine whether or not a sample is injected; applying voltage between the working electrode and one of the other electrodes and re-detecting the amount of current flowing through the working electrode; and acquiring and displaying a concentration value as a sample reaction result corresponding to the amount of detected current.

Abstract translation: 公开了一种在具有工作电极和其他电极的生物传感器上测量样品反应结果的方法，包括：在工作电极和每个其他电极之间施加电压并检测流过工作电极的电流量，以确定是否 注入样品; 在工作电极和其他电极之间施加电压，并重新检测流过工作电极的电流量; 并且获取和显示浓度值作为与检测到的电流量对应的样品反应结果。

公开(公告)号：US20080128278A1

公开(公告)日：2008-06-05

申请号：US11682910

申请日：2007-03-07

Applicant: Byeong-woo Bae ,  Sung-dong Lee ,  Hong-seong Suk ,  Jin-a Yoo ,  Ji-su Kim ,  Jeong-yun Yang

Inventor： Byeong-woo Bae ,  Sung-dong Lee ,  Hong-seong Suk ,  Jin-a Yoo ,  Ji-su Kim ,  Jeong-yun Yang

IPC: G01N27/327

CPC classification number: C12Q1/001 ,  G01N27/3272

Abstract: A biosensor measuring an analyte contained in a sample is disclosed, including: a lower insulating substrate having formed thereon a working electrode and a reference electrode connected to lead terminals through leads, and an enzyme reactant layer formed on the electrodes to react with the analyte contained in the sample; a spacer which is interposed between the lower substrate and an upper substrate, is attached to the lower and upper substrates, and has a sample guide area to guide the sample to reach to the electrodes through the enzyme reactant layer; and an upper insulating substrate which faces the lower substrate through the spacer, where a dummy electrode is formed on the lower substrate, the dummy electrode being separated from the working electrode and the reference electrode, fixing the enzyme reactant layer, and being not connected to the leads.

Abstract translation: 公开了一种测量样品中包含的分析物的生物传感器，包括：下部绝缘基板，其上形成有工作电极和通过引线连接到引线端子的参考电极，以及形成在电极上以与所包含的分析物反应的酶反应物层 在样品中 插入在下基板和上基板之间的间隔件附接到下基板和上基板，并且具有引导样品以通过酶反应物层到达电极的样本引导区域; 以及通过间隔件面向下基板的上绝缘基板，其中在下基板上形成虚拟电极，所述虚拟电极与工作电极和参比电极分离，固定酶反应物层，并且不连接到 线索。

公开(公告)号：US20080110768A1

公开(公告)日：2008-05-15

申请号：US11654284

申请日：2007-01-17

Applicant: Byeong-woo Bae ,  Sung-dong Lee ,  Hong-seong Suk ,  Jin-a Yoo ,  Ji-su Kim ,  Jeong-yun Yang

Inventor： Byeong-woo Bae ,  Sung-dong Lee ,  Hong-seong Suk ,  Jin-a Yoo ,  Ji-su Kim ,  Jeong-yun Yang

IPC: C12M1/34

CPC classification number: C12Q1/001 ,  G01N27/3272

Abstract: A biosensor measuring an analyte contained in a sample includes a lower insulating substrate having at least one electrode and an enzyme reactant layer which is formed on the electrode to react with the analyte; a spacer which is attached to the lower substrate and an upper substrate and is provided to form a sample injection area to guide the sample to the electrode through the enzyme reactant layer; and an upper insulating substrate which faces the lower substrate and has an air discharge area to discharge air which is absorbed together with the sample through the sample injection area, where the air discharge area is formed on a layer different from that of the sample injection area.

Abstract translation: 测量样品中包含的分析物的生物传感器包括具有至少一个电极的下绝缘基底和形成在电极上以与分析物反应的酶反应物层; 附接到下基板和上基板的间隔件，并且被提供以形成样品注入区域，以通过酶反应物层将样品引导到电极; 以及面向下基板并具有空气排出区域的上绝缘基板，其通过样品注入区域与样品一起吸收的空气排出，其中空气排出区域形成在与样品注入区域不同的层上 。