公开(公告)号：US08293189B2

公开(公告)日：2012-10-23

申请号：US12722183

申请日：2010-03-11

申请人： Byeong-Woo Bae ,  Sung-Dong Lee ,  Byung-Hoon Kho ,  Ji-Eon Ryu ,  Jin-Kyeong Kim ,  Hyou-Arm Joung

发明人： Byeong-Woo Bae ,  Sung-Dong Lee ,  Byung-Hoon Kho ,  Ji-Eon Ryu ,  Jin-Kyeong Kim ,  Hyou-Arm Joung

IPC分类号： G01N31/22

CPC分类号： G01N33/525 ,  C12Q1/60 ,  G01N33/92

摘要： Disclosed is a test strip for measuring medical data, in which a hydrophilic material is introduced to improve the spreadability of blood. Having the structure comprising a blood-filtering layer designed to filter off either or both of erythrocytes and low-density lipoprotein (LDL) cholesterol from an applied blood sample; a reaction layer in which the blood sample free of erythrocytes and/or low-density lipoprotein (LDL) cholesterol is reacted with an reagent, and a hydrophilic material, intercalated between the blood-filtering layer and the reaction layer, for uniformly spreading the blood sample filtered through the filtering layer, the blood-filtering layer and the reaction layer being stacked between the lower support and the upper cover, the test strip prevents the infiltration of erythrocytes into the reaction layer and improves the spreadability of blood to reduce measurement errors, thus bringing about higher reproducibility.

摘要翻译： 公开了一种用于测量医疗数据的测试条，其中引入亲水材料以改善血液的铺展性。 具有包括血液过滤层的结构，设计用于从施用的血液样品中过滤掉红细胞和低密度脂蛋白（LDL）胆固醇中的任一者或两者; 将没有红细胞和/或低密度脂蛋白（LDL）胆固醇的血液样品与试剂反应的反应层和插入血液过滤层和反应层之间的亲水材料，以均匀地分散血液 样品通过过滤层过滤，血液过滤层和反应层堆叠在下支撑体和上盖之间，试纸片防止红细胞浸入反应层，提高血液的铺展性，减少测量误差， 从而带来更高的再现性。

公开(公告)号：US08221703B2

公开(公告)日：2012-07-17

申请号：US12722165

申请日：2010-03-11

申请人： Byeong-Woo Bae ,  Sung-Dong Lee ,  Byung-Hoon Kho ,  Ji-Eon Ryu ,  Jin-Kyeong Kim ,  Hyou-Arm Joung ,  Ku-Cheol Ahn

发明人： Byeong-Woo Bae ,  Sung-Dong Lee ,  Byung-Hoon Kho ,  Ji-Eon Ryu ,  Jin-Kyeong Kim ,  Hyou-Arm Joung ,  Ku-Cheol Ahn

IPC分类号： A61B10/00

CPC分类号： G01N33/4875 ,  A61B5/14532 ,  A61B5/1468 ,  A61B5/15 ,  A61B5/150022 ,  A61B5/150259 ,  A61B5/150343 ,  A61B5/150358 ,  A61B5/157 ,  A61B2562/0295 ,  B01L3/5023

摘要： Disclosed herein is a device for collecting a sample, which is intended to dispense a received sample onto a measurement strip. The device includes a main body and a pair of receiving pieces. The receiving pieces protrude from a first end of the main body in such a way as to be spaced apart from each other while facing each other, and receive the sample by capillary force acting on a space which is defined between the receiving pieces and which is open on right, left and bottom sides. The device allows the received sample to be easily transferred to a reaction zone of a measurement strip, and enables the sample to be completely absorbed by the reaction zone because of capillary force in a receiving area when the device comes into contact with the reaction zone of the strip.

摘要翻译： 本文公开了一种用于收集样品的装置，其旨在将接收的样品分配到测量条上。 该装置包括主体和一对接收件。 接收件从主体的第一端以彼此相对的方式突出，并且通过作用在限定在接收件之间的空间的毛细作用力接收样品， 在右侧，左侧和底侧打开。 该装置允许所接收的样品容易地转移到测量条的反应区，并且使得样品在接收区域中由于毛细管力而被反应区完全吸收，当装置与反应区接触时 带子。

公开(公告)号：US20100311154A1

公开(公告)日：2010-12-09

申请号：US12722183

申请日：2010-03-11

申请人： Byeong-Woo BAE ,  Sung-Dong LEE ,  Byung-Hoon KHO ,  Ji-Eon RYU ,  Jin-Kyeong KIM ,  Hyou-Arm JOUNG

发明人： Byeong-Woo BAE ,  Sung-Dong LEE ,  Byung-Hoon KHO ,  Ji-Eon RYU ,  Jin-Kyeong KIM ,  Hyou-Arm JOUNG

IPC分类号： C12M1/12

CPC分类号： G01N33/525 ,  C12Q1/60 ,  G01N33/92

摘要： Disclosed is a test strip for measuring medical data, in which a hydrophilic material is introduced to improve the spreadability of blood. Having the structure comprising a blood-filtering layer designed to filter off either or both of erythrocytes and low-density lipoprotein (LDL) cholesterol from an applied blood sample; a reaction layer in which the blood sample free of erythrocytes and/or low-density lipoprotein (LDL) cholesterol is reacted with an reagent, and a hydrophilic material, intercalated between the blood-filtering layer and the reaction layer, for uniformly spreading the blood sample filtered through the filtering layer, the blood-filtering layer and the reaction layer being stacked between the lower support and the upper cover, the test strip prevents the infiltration of erythrocytes into the reaction layer and improves the spreadability of blood to reduce measurement errors, thus bringing about higher reproducibility.

摘要翻译： 公开了一种用于测量医疗数据的测试条，其中引入亲水材料以改善血液的铺展性。 具有包括血液过滤层的结构，设计用于从施用的血液样品中过滤掉红细胞和低密度脂蛋白（LDL）胆固醇中的任一者或两者; 将没有红细胞和/或低密度脂蛋白（LDL）胆固醇的血液样品与试剂反应的反应层和插入血液过滤层和反应层之间的亲水材料，以均匀地分散血液 样品通过过滤层过滤，血液过滤层和反应层堆叠在下支撑体和上盖之间，试纸片防止红细胞浸入反应层，提高血液的铺展性，减少测量误差， 从而带来更高的再现性。

公开(公告)号：US20090093012A1

公开(公告)日：2009-04-09

申请号：US12025443

申请日：2008-02-04

申请人： Byeong-woo BAE ,  Sung-dong LEE ,  Min-sun KIM ,  Jae-hyun YOO ,  Hyoung-soo KIM ,  Ki-won LEE ,  Ju-pyo HONG

发明人： Byeong-woo BAE ,  Sung-dong LEE ,  Min-sun KIM ,  Jae-hyun YOO ,  Hyoung-soo KIM ,  Ki-won LEE ,  Ju-pyo HONG

IPC分类号： C12Q1/02 ,  C12M1/00 ,  C12M1/34

CPC分类号： G01N33/723 ,  B01L3/502 ,  B01L2200/0621 ,  B01L2400/0457 ,  G01N33/54306 ,  G01N33/726

摘要： A reaction cassette for a glycated hemoglobin meter and a measuring method thereof are provided. The reaction cassette for the glycated hemoglobin meter includes: a first zone receiving a first reagent and a blood sample; a second zone receiving a second reagent; a reaction zone in which the blood sample reacts with the first reagent, or through which the second reagent passes to react with a first blood sample mixture obtained by reacting the blood sample with the first reagent; and a measurement zone measuring an amount of total hemoglobin in the first blood sample mixture, or measuring an amount of glycated hemoglobin in a second blood sample mixture obtained by reacting the first blood sample mixture with the second reagent, wherein the blood sample, the first reagent, and the second reagent move between the reaction zone and the measurement zone according to a rotation angle of the reaction cassette when the reaction cassette is rotated. Therefore, since the reaction cassette rotates automatically, it is possible to measure the amount of glycated hemoglobin in a blood sample through simple manipulation and reduce a manufacturing time. Furthermore, since reagents are supplied to the reaction cassette from a separate reagent pack, it is possible to resolve storage and distribution problems of the reaction cassette, which occur when reagents are stored in the reaction cassette.

摘要翻译： 提供了糖化血红蛋白计的反应盒及其测定方法。 糖化血红蛋白计的反应盒包括：接收第一试剂和血液样品的第一区; 接收第二试剂的第二区域; 血液样品与第一试剂反应的反应区域，或第二试剂通过的反应区域与通过使血液样品与第一试剂反应获得的第一血液样品混合物反应; 以及测量第一血液样品混合物中的总血红蛋白量的测量区域，或者测量通过使第一血液样品混合物与第二试剂反应获得的第二血液样品混合物中的糖化血红蛋白的量，其中，血液样品，第一 试剂，第二试剂在反应盒旋转时根据反应盒的旋转角度在反应区和测量区之间移动。 因此，由于反应盒自动旋转，因此可以通过简单的操作来测量血液样品中的糖化血红蛋白的量，并减少制造时间。 此外，由于将试剂从单独的试剂盒供给到反应盒中，因此可以解决当试剂储存在反应盒中时发生的反应盒的储存和分配问题。

公开(公告)号：US20050161323A1

公开(公告)日：2005-07-28

申请号：US10514236

申请日：2002-10-04

申请人： Byung-Woo Bae ,  Heon-Kwon Lee ,  Sung-Dong Lee ,  Mi-Joong Kwon

发明人： Byung-Woo Bae ,  Heon-Kwon Lee ,  Sung-Dong Lee ,  Mi-Joong Kwon

IPC分类号： C12Q1/26 ,  C12Q1/00 ,  G01N33/487 ,  G01N27/26

CPC分类号： C12Q1/001 ,  G01N27/3272

摘要： Disclosed is a biosensor for quantifying a specific substance contained in a biological sample comprising: an electrically insulating base plate; a plurality of lead terminals formed on the base plate; a plurality of lead wires connected to the lead terminals, respectively; an electrode system including two working electrodes and one reference electrode connected to the lead wires, respectively; an insulating layer for insulating the electrodes; an enzyme reaction layer formed on the insulating layer and the electrodes; a spacer formed on the enzyme reaction layer so as to ensure a sufficient space for receiving a sample; and a cover formed on the spacer, wherein the spacer has a sample introduction port opened at one side of the spacer, and the cover has at least one slit for venting air existing in a sample receiving space defined by the spacer and the cover, the slit extending to above the electrodes from one end of the cover.

摘要翻译： 公开了一种用于定量生物样品中所含特定物质的生物传感器，包括：电绝缘基板; 形成在所述基板上的多个引线端子; 多个引线分别连接到引线端子; 电极系统，分别包括连接到引线的两个工作电极和一个参考电极; 用于绝缘电极的绝缘层; 在所述绝缘层和所述电极上形成的酶反应层; 在酶反应层上形成间隔物，以确保足够的空间用于接收样品; 以及形成在所述间隔件上的盖，其中所述间隔件具有在所述间隔件的一侧开口的样品引入口，并且所述盖具有至少一个狭缝，用于排出存在于由所述间隔件和所述盖限定的样品容纳空间中的空气， 狭缝从盖的一端延伸到电极的上方。

公开(公告)号：US09180458B2

公开(公告)日：2015-11-10

申请号：US11521046

申请日：2006-09-14

申请人： Byeong-woo Bae ,  Sung-dong Lee ,  Hong-seong Suk ,  Jina Yoo ,  Ki-won Lee ,  Jong-won Hong ,  Duck-sung Nam

发明人： Byeong-woo Bae ,  Sung-dong Lee ,  Hong-seong Suk ,  Jina Yoo ,  Ki-won Lee ,  Jong-won Hong ,  Duck-sung Nam

IPC分类号： B01L3/00 ,  G01N33/487 ,  G01N35/00

CPC分类号： G01N27/3274 ,  B01L3/545 ,  G01N33/48771 ,  G01N2035/00772

摘要： A biosensor is provided, including an identification information recording unit having identification information of the biosensor recorded thereon, where the identification information recording unit is a color tag that is attached on the biosensor and indicates the identification information by color, chroma of color, or arrangement pattern of colors. An apparatus for reading identification information of a biosensor is provided, including: a biosensor sensing unit detecting the biosensor; a light-emitting unit emitting light on an identification information recording unit when the biosensor sensing unit detects the biosensor, the identification information recording unit having the identification information of the biosensor recorded thereon; a light-receiving unit that receives the light emitted from the light-emitting unit, and reflected or refracted by or passing through the identification information recording section; and an identification information reading unit analyzing the light received by the light-receiving unit and reading the identification information of the biosensor.

摘要翻译： 提供一种生物传感器，包括识别信息记录单元，其具有记录在其上的生物传感器的识别信息，其中识别信息记录单元是附着在生物传感器上的颜色标签，并通过颜色，颜色色彩或布置指示识别信息 颜色图案 提供一种用于读取生物传感器的识别信息的装置，包括：生物传感器感测单元检测生物传感器; 当生物传感器感测单元检测到生物传感器时，在识别信息记录单元上发光的发光单元，其上记录有生物传感器的识别信息的识别信息记录单元; 光接收单元，其接收从所述发光单元发射并被所述识别信息记录部分反射或折射或通过所述识别信息记录部分的光; 以及识别信息读取单元，分析由所述光接收单元接收的光并读取所述生物传感器的识别信息。

公开(公告)号：US08785095B2

公开(公告)日：2014-07-22

申请号：US13326994

申请日：2011-12-15

申请人： Se-young Yoon ,  Song-won Hyun ,  Hong-Chul Shin ,  Sung-dong Lee ,  Jong-in Kim

发明人： Se-young Yoon ,  Song-won Hyun ,  Hong-Chul Shin ,  Sung-dong Lee ,  Jong-in Kim

IPC分类号： G03G9/00

CPC分类号： G03G15/08 ,  G03G9/0806 ,  G03G9/0808 ,  G03G9/0819 ,  G03G9/097 ,  G03G9/09708 ,  G03G9/09716 ,  G03G9/09725

摘要： Disclosed is a toner for developing an electrostatic charge image, including a toner particle coated with a combination of sol-gel silica particles, hydrophobically surface-treated fumed silica particles, and hydrophobically surface-treated titanium dioxide particles.

摘要翻译： 公开了用于显影静电荷图像的调色剂，其包括涂覆有溶胶 - 凝胶二氧化硅颗粒，疏水表面处理的热解二氧化硅颗粒和疏水表面处理的二氧化钛颗粒的组合的调色剂颗粒。

公开(公告)号：US08702923B2

公开(公告)日：2014-04-22

申请号：US13010098

申请日：2011-01-20

申请人： Byeong-woo Bae ,  Sung-dong Lee ,  Hong-seong Suk ,  Jin-a Yoo

发明人： Byeong-woo Bae ,  Sung-dong Lee ,  Hong-seong Suk ,  Jin-a Yoo

IPC分类号： G01N27/26 ,  G01N27/327

CPC分类号： C12Q1/006 ,  G01N27/3272

摘要： Disclosed is a method of measuring sample reaction results on a biosensor having a working electrode and other electrodes, including: applying voltage between the working electrode and each of the other electrodes and detecting the amount of current flowing through the working electrode to determine whether or not a sample is injected; applying voltage between the working electrode and one of the other electrodes and re-detecting the amount of current flowing through the working electrode; and acquiring and displaying a concentration value as a sample reaction result corresponding to the amount of detected current.

摘要翻译： 公开了一种在具有工作电极和其他电极的生物传感器上测量样品反应结果的方法，包括：在工作电极和每个其他电极之间施加电压并检测流过工作电极的电流量，以确定是否 注入样品; 在工作电极和其他电极之间施加电压，并重新检测流过工作电极的电流量; 并且获取和显示浓度值作为与检测到的电流量对应的样品反应结果。

公开(公告)号：US20120305394A1

公开(公告)日：2012-12-06

申请号：US13588025

申请日：2012-08-17

申请人： Byeong-woo BAE ,  Sung-dong LEE ,  Hong-seong SUK ,  Jina YOO ,  Ki-won LEE ,  Jong-won HONG ,  Duck-sung NAM

发明人： Byeong-woo BAE ,  Sung-dong LEE ,  Hong-seong SUK ,  Jina YOO ,  Ki-won LEE ,  Jong-won HONG ,  Duck-sung NAM

IPC分类号： G01N27/327

CPC分类号： G01N27/3274 ,  B01L3/545 ,  G01N33/48771 ,  G01N2035/00772

摘要： An apparatus for reading identification information of a biosensor is provided, including a biosensor sensing unit detecting the biosensor, a light-emitting unit emitting light on an identification information recording unit when the biosensor sensing unit detects the biosensor, the identification information recording unit having the identification information of the biosensor recorded thereon, a light-receiving unit that receives the light emitted from the light-emitting unit, and reflected or refracted by or passing through the identification information recording section, and an identification information reading unit analyzing the light received by the light-receiving unit and reading the identification information of the biosensor.

摘要翻译： 提供一种用于读取生物传感器的识别信息的装置，包括检测生物传感器的生物传感器感测单元，当生物传感器感测单元检测到生物传感器时在识别信息记录单元上发光的发光单元，具有 记录在其上的生物传感器的识别信息，接收从发光单元发射并被识别信息记录部分反射或折射或通过的光的光接收单元，以及识别信息读取单元， 光接收单元并读取生物传感器的识别信息。

公开(公告)号：US20120088253A1

公开(公告)日：2012-04-12

申请号：US13329689

申请日：2011-12-19

申请人： Byeong-Woo Bae ,  Sung-Dong Lee ,  Hyong-Soo Kim

发明人： Byeong-Woo Bae ,  Sung-Dong Lee ,  Hyong-Soo Kim

IPC分类号： G01N33/72

CPC分类号： G01N33/723

摘要： Provided is a method for measuring glycated hemoglobin. The method includes a hemolysis step of hemolyzing a blood sample with a hemolysate, a reaction step of reacting the hemolyzed blood sample with bead conjugates in which beads are conjugated with glycated hemoglobin binding materials, a first measuring step of measuring the amount of total hemoglobin in blood, an isolation step of isolating normal hemoglobin from the glycated hemoglobin conjugated with the bead conjugates, a second measuring step of measuring the amount of glycated hemoglobin in blood, and a calculation step of calculating the concentration of glycated hemoglobin in the blood sample based on the measured amounts of total hemoglobin and glycated hemoglobin in the blood sample.

摘要翻译： 提供了测定糖化血红蛋白的方法。 该方法包括使溶血液溶血血液样品的溶血步骤，使溶血的血液样品与珠粒与糖化血红蛋白结合材料共轭的珠缀合物反应的反应步骤，测量总血红蛋白量的第一测量步骤 血液，从与珠缀合物缀合的糖化血红蛋白分离正常血红蛋白的分离步骤，测定血液中糖化血红蛋白量的第二测定步骤，计算血液样品中糖化血红蛋白浓度的计算步骤，基于 血样中总血红蛋白和糖化血红蛋白的测定量。