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公开(公告)号：US10183176B2
公开(公告)日：2019-01-22
申请号：US13131390
申请日：2009-12-04
摘要： A therapeutic apparatus comprising: a magnetic resonance imaging system adapted for acquiring a set of magnetic resonance imaging data in an imaging zone, the magnetic resonance imaging system comprising a means for generating a magnetic field, —a guiding means adapted for guiding a beam of charged particles to a target zone within a subject, wherein the imaging zone comprises the target zone, a zone determination means adapted for determining the location of the target zone within the subject using the set of magnetic resonance imaging data, a trajectory calculation means adapted for calculating a trajectory of the beam using magnetic field data being descriptive of the magnetic field such that the calculated trajectory reaches the target zone, a control means adapted for controlling the guiding means using the calculated trajectory such that the beam follows the calculated trajectory.
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公开(公告)号：US20130131433A1
公开(公告)日：2013-05-23
申请号：US13521228
申请日：2011-01-05
申请人： Ulrich Katscher , Oliver Lips , Christian Findeklee , Christoph Leussler , Kay Nehrke , Daniel Wirtz , Johannes Adrianus Overweg
发明人： Ulrich Katscher , Oliver Lips , Christian Findeklee , Christoph Leussler , Kay Nehrke , Daniel Wirtz , Johannes Adrianus Overweg
IPC分类号： A61N5/10
CPC分类号： A61N5/1064 , A61B2017/00084 , A61B2090/374 , A61N1/403 , A61N5/10 , A61N5/1084 , A61N7/00 , A61N7/02 , A61N2005/007 , A61N2005/1055 , G01R33/4804 , G01R33/4808
摘要： The invention provides for a therapeutic apparatus comprising a tissue heating system (302, 480, 482). The therapeutic apparatus further comprises a magnetic resonance imaging system (300) for acquiring magnetic resonance thermometry data (366) from nuclei of a subject (318) located within an imaging volume (330). The therapeutic apparatus further comprises a radiation therapy system (304, 592) for irradiating an irradiation volume (316, 516) of the subject, wherein the irradiation volume is within the imaging volume. The therapeutic apparatus further comprises a controller (354) for controlling the therapeutic apparatus. The controller is adapted for acquiring (100, 210) magnetic resonance thermometry data repeatedly using the magnetic resonance imaging system. The controller is adapted for heating (102, 208) at least the irradiation volume using the tissue heating system. The heating is controlled using the magnetic resonance thermometry data. The controller is adapted for irradiating (104, 208) the irradiation volume.
摘要翻译： 本发明提供一种包括组织加热系统（302,480,482）的治疗设备。 治疗装置还包括用于从位于成像体积（330）内的对象（318）的核获取磁共振测温数据（366）的磁共振成像系统（300）。 治疗装置还包括用于照射受试者的照射体积（316,516）的放射治疗系统（304,592），其中照射体积在成像体积内。 治疗装置还包括用于控制治疗装置的控制器（354）。 控制器适于使用磁共振成像系统重复地获取（100,210）磁共振测温数据。 控制器适于使用组织加热系统加热（102,208）至少照射体积。 使用磁共振测温数据来控制加热。 控制器适于照射（104,208）照射体积。
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公开(公告)号：US20110087090A1
公开(公告)日：2011-04-14
申请号：US12997020
申请日：2009-06-16
CPC分类号： G01R33/4808 , A61B5/055 , A61N5/1038 , A61N5/1049 , A61N5/1067 , A61N2005/1055 , G01R33/56 , G01R33/5608 , G01R33/5611
摘要： A radiation therapy system comprises: a radiation therapy subsystem (20, 22, 32) configured to perform radiation therapy by applying radiation pulses to a region of a subject at pulse intervals (Tpi); a magnetic resonance (MR) imaging subsystem (10, 16, 30, 36) configured to acquire a dataset of MR imaging data samples from the region of the subject over one or more MR sampling intervals (TAQ) that are longer than the pulse intervals, the one or more MR sampling intervals overlapping at least some of the pulse intervals; a synchronizer (40) configured to identify MR imaging data samples of the dataset whose acquisition times overlap pulse intervals; and a reconstruction processor (44) configured to reconstruct the dataset without the measured values for the MR imaging data samples identified as having acquisition times overlapping pulse intervals to generate a reconstructed MR image.
摘要翻译： 一种放射治疗系统包括：放射治疗子系统（20,22,32），其被配置为通过以脉冲间隔（Tpi）对受检者的区域施加辐射脉冲来执行放射治疗; 配置成通过比脉冲间隔长的一个或多个MR采样间隔（TAQ）从受检者的区域获取MR成像数据样本的数据集的磁共振（MR）成像子系统（10,16,30,36） 所述一个或多个MR采样间隔与所述脉冲间隔中的至少一些重叠; 同步器（40），其被配置为识别所述数据集的MR成像数据样本，其采集时间与脉冲间隔重叠; 以及重建处理器（44），其被配置为重建所述数据集而没有被识别为具有重叠脉冲间隔的获取时间的MR成像数据样本的测量值，以生成重建的MR图像。
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公开(公告)号：US20080197846A1
公开(公告)日：2008-08-21
申请号：US12066269
申请日：2006-09-08
申请人： Romhild Martijn Hoogeveen , Jan Frans Lodewijk De Becker , Peter Boernert , Johannes Adrianus Overweg
发明人： Romhild Martijn Hoogeveen , Jan Frans Lodewijk De Becker , Peter Boernert , Johannes Adrianus Overweg
IPC分类号： G01R33/54
CPC分类号： G01R33/561
摘要： A magnetic resonance imaging system comprises a signal acquisition system to acquire magnetic resonance signals. A reconstructor reconstructs magnetic resonance images from the acquired magnetic resonance signals. The signal acquisition system and/or the reconstructor are controlled to perform overhead activities separately from actual acquisition of the magnetic resonance signals notably for different contrast types. Accordingly, time efficient signal acquisition for multiple contrasts is achieved.
摘要翻译： 磁共振成像系统包括用于获取磁共振信号的信号采集系统。 重构器从获取的磁共振信号重建磁共振图像。 控制信号采集系统和/或重构器以独立于实际获取磁共振信号以独特地对于不同对比度类型进行开销活动。 因此，实现了多个对比度的时间有效的信号采集。
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5.发明授权Vertical field type MRI apparatus with a conical cavity situated in the main magnet 失效垂直场型MRI装置，其具有位于主磁体中的锥形腔公开(公告)号：US06741078B2
公开(公告)日：2004-05-25
申请号：US09962297
申请日：2001-09-25
IPC分类号： G01V300
CPC分类号： G01R33/3806 , G01R33/3815
摘要： The invention relates to a vertical field type MRI apparatus provided with a superconducting coil system 20a, 20b for generating a substantially homogeneous magnetic field in an imaging volume 18 of the apparatus. The coil system includes a circular outer coil 28 and a supplementary coil 30 which is positioned in the same plane 32 as and within the outer coil, which coils conduct opposite currents. The ratio Da/Do of the diameter Da of the supplementary coil to the diameter Do of the outer coil lies between 0,7 and 0,9. Further coils 34 to 38, 40 to 46 for making the field even more homogeneous are preferably located on a conical surface 48, 50 within the first mentioned coils 28, 30 in such a manner that a recess is formed in which a conically shaped gradient coil system 52 can be accommodated, with the result that the expensive outer coil 28 and the supplementary coil 30 can be arranged at an as short as possible distance from the space for receiving the patient to be examined.
摘要翻译： 本发明涉及一种具有超导线圈系统20a，20b的垂直场型MRI设备，用于在该装置的成像体积18中产生基本均匀的磁场。 线圈系统包括圆形的外部线圈28和辅助线圈30，辅助线圈30位于与外部线圈内部和外部线圈中相同的平面32中，该线圈传导相反的电流。 辅助线圈的直径Da与外部线圈的直径Do的比Da / Do在0,7和0,9之间。 用于使场更均匀的另外的线圈34至38,40至46优选地位于第一提及的线圈28,30内的锥形表面48,50上，使得形成凹部，其中形成锥形梯度线圈 可以容纳系统52，结果是昂贵的外部线圈28和辅助线圈30可以布置在与用于接收待检查的患者的空间尽可能短的距离处。
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6.发明授权Vertical field type MRI apparatus with a conical gradient coil situated in the main magnet 失效垂直场型MRI装置，其具有位于主磁体中的锥形梯度线圈公开(公告)号：US06618606B2
公开(公告)日：2003-09-09
申请号：US09962654
申请日：2001-09-25
IPC分类号： A61B5055
CPC分类号： G01R33/3806 , G01R33/3815
摘要： A vertical field type MRI apparatus is provided with a superconducting coil system for generating a substantially homogeneous magnetic field in an imaging volume of the apparatus. The coil system includes a circular outer coil and a supplementary coil which is positioned in the same plane as and within the outer coil, which coils conduct opposite currents. The ratio Da/Do of the diameter Da of the supplementary coil to the diameter Do of the outer coil lies between 0.7 and 0.9. Further coils for making the field more homogeneous are preferably located on a conical surface within the circular outer coil and supplementary coil in such a manner that a recess is formed in which a conically shaped gradient coil system can be accommodated, with the result that the expensive outer coil and the supplementary coil can be arranged at an as short as possible distance from the space for receiving the patient to be examined.
摘要翻译： 垂直场型MRI装置设置有超导线圈系统，用于在装置的成像体积中产生基本均匀的磁场。 线圈系统包括圆形的外部线圈和辅助线圈，该线圈与外部线圈位于同一平面内，该线圈导致相反的电流。 辅助线圈的直径Da与外部线圈的直径Do的比Da / Do在0.7和0.9之间。 用于使场更均匀的更多线圈优选地位于圆形外线圈和辅助线圈内的锥形表面上，使得形成凹槽，其中可容纳锥形梯度线圈系统，结果是昂贵的 外线圈和辅助线圈可以布置在与用于接收待检查患者的空间尽可能短的距离处。
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公开(公告)号：US10173077B2
公开(公告)日：2019-01-08
申请号：US13131476
申请日：2009-11-19
摘要： A therapeutic apparatus comprising: a magnetic resonance imaging system adapted for acquiring a set of magnetic resonance imaging data in an imaging zone, wherein the magnetic resonance imaging system comprises a means for generating a magnetic field, a guiding means adapted for guiding a beam of charged particles to a target zone within a subject such that the beam encloses an angle with the magnetic field lines of the magnetic field within the imaging zone, the angle being between 0 degrees and 30 degrees, wherein the imaging zone comprises the target zone, a zone determination means for determining the location of the target zone within the subject using the set of magnetic resonance imaging data.
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公开(公告)号：US09664763B2
公开(公告)日：2017-05-30
申请号：US14118910
申请日：2012-05-31
IPC分类号： G01V3/00 , G01R33/56 , G01R33/48 , A61N5/10 , G01R33/3873 , G01R33/3875
CPC分类号： G01R33/56 , A61N5/1049 , A61N2005/1055 , G01R33/3873 , G01R33/3875 , G01R33/4808
摘要： A method of correcting a magnetic field of an MRI radiotherapy apparatus (300) includes a magnetic resonance imaging system (302) and a radiation therapy system (304). The MRI system includes a magnet (306) for generating the magnetic field within an imaging zone 318. The magnet generates a magnetic field with a zero crossing (346, 404) outside of the imaging zone. The medical apparatus further comprises a gantry (332) configured for rotating a ferromagnetic component (336, 510) about a rotational axis (333). The method comprises the step of installing (100, 200) a magnetic correcting element (348, 900, 1000) located on a radial path (344, 504) perpendicular to the rotational axis. The magnetic correcting element is positioned on the radial path such that change in the magnetic field within the imaging zone due to the ferromagnetic component is reduced. The method further comprises repeatedly: measuring (102, 202, 1204) the magnetic field within the imaging zone; determining (104, 204, 1206) the change in the magnetic field in the imaging zone; and adjusting (106, 206, 1208) the position of the magnetic correcting element along the radial path if the change in the magnetic field is above a predetermined threshold.
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公开(公告)号：US20140084926A1
公开(公告)日：2014-03-27
申请号：US14118910
申请日：2012-05-31
IPC分类号： G01R33/56
CPC分类号： G01R33/56 , A61N5/1049 , A61N2005/1055 , G01R33/3873 , G01R33/3875 , G01R33/4808
摘要： A method of correcting a magnetic field of an MRI radiotherapy apparatus (300) comprising a magnetic resonance imaging system (302) and a radiation therapy system (304). The MRI system includes a magnet (306) for generating the magnetic field within an imaging zone 318. The magnet generates a magnetic field with a zero crossing (346, 404) outside of the imaging zone. The medical apparatus further comprises a gantry (332) configured for rotating a ferromagnetic component (336, 510) about a rotational axis (333). The method comprises the step of installing (100, 200) a magnetic correcting element (348, 900, 1000) located on a radial path (344, 504) perpendicular to the rotational axis. The magnetic correcting element is positioned on the radial path such that change in the magnetic field within the imaging zone due to the ferromagnetic component is reduced. The method further comprises repeatedly: measuring (102, 202, 1204) the magnetic field within the imaging zone; determining (104, 204, 1206) the change in the magnetic field in the imaging zone; and adjusting (106, 206, 1208) the position of the magnetic correcting element along the radial path if the change in the magnetic field is above a predetermined threshold.
摘要翻译： 一种校正包括磁共振成像系统（302）和放射治疗系统（304）的MRI放射治疗装置（300）的磁场的方法。 MRI系统包括用于在成像区域318内产生磁场的磁体（306）。磁体在成像区域外部产生具有零交叉（346,404）的磁场。 医疗设备还包括构造成围绕旋转轴线（333）旋转铁磁部件（336,510）的台架（332）。 该方法包括安装（100,200）位于垂直于旋转轴线的径向路径（344,504）上的磁性校正元件（348,900,1000）的步骤。 磁性校正元件位于径向路径上，使得由于铁磁性成分引起的成像区域内的磁场的变化减小。 该方法还包括：重复地：测量（102,202,1204）成像区域内的磁场; 确定（104,204,1206）所述成像区域中的磁场的变化; 以及如果所述磁场的变化高于预定阈值，则调整所述磁修正元件沿所述径向路径的位置（106,206,1208）。
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公开(公告)号：US20110237859A1
公开(公告)日：2011-09-29
申请号：US13131390
申请日：2009-12-04
IPC分类号： A61B5/055
CPC分类号： A61N5/1031 , A61B5/055 , A61N5/1037 , A61N5/1042 , A61N2005/1055 , A61N2005/1087
摘要： A therapeutic apparatus comprising: a magnetic resonance imaging system adapted for acquiring a set of magnetic resonance imaging data in an imaging zone, the magnetic resonance imaging system comprising a means for generating a magnetic field, a guiding means adapted for guiding a beam of charged particles to a target zone within a subject, wherein the imaging zone comprises the target zone, a zone determination means adapted for determining the location of the target zone within the subject using the set of magnetic resonance imaging data, a trajectory calculation means adapted for calculating a trajectory of the beam using magnetic field data being descriptive of the magnetic field such that the calculated trajectory reaches the target zone, a control means adapted for controlling the guiding means using the calculated trajectory such that the beam follows the calculated trajectory.
摘要翻译： 一种治疗装置，包括：磁共振成像系统，适于在成像区域中获取一组磁共振成像数据，所述磁共振成像系统包括用于产生磁场的装置，适于引导带电粒子束的引导装置 到目标区域，其中所述成像区域包括所述目标区域，适于使用所述一组磁共振成像数据确定所述对象内的所述目标区域的位置的区域确定装置，适于计算 使用描述磁场的磁场数据的光束的轨迹，使得所计算的轨迹到达目标区域;控制装置，其适于使用所计算的轨迹来控制引导装置，使得光束遵循所计算的轨迹。
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