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1.发明授权Optical scanning configurations, systems, and methods involving at least one actuator for scanning a scan head 有权涉及用于扫描扫描头的至少一个致动器的光学扫描配置，系统和方法公开(公告)号：US07599060B2
公开(公告)日：2009-10-06
申请号：US12222820
申请日：2008-08-18
IPC分类号： G01N21/64
CPC分类号： G01N21/645 , F21V29/54 , F21V29/677 , F21V29/763 , G01N21/6452 , G01N2021/6439 , G01N2201/062 , G01N2201/1211 , G05D23/1919 , G05D23/20
摘要： An optical system includes a sample substrate having a surface, the surface defining a 2-dimensional sample plane. The system includes an excitation source configured to provide excitation light to the sample substrate. The system further includes an optical detector configured to receive emission light from the sample substrate and generate detection data. The system also includes a scan head configured at least (i) to direct the excitation light towards the sample substrate, (ii) to receive emission light from the sample substrate and direct the emission light towards the optical detector, and (iii) for scanning relative to the sample substrate. The system includes at least one actuator configured to scan the scan head relative to the sample substrate, the at least one actuator being configured to provide at least one of (1) a relative linear motion and a relative angular motion about a rotational axis generally perpendicular to the sample plane and (2) two relative angular motions about two respectively different rotational axes generally perpendicular to the sample plane.
摘要翻译： 光学系统包括具有表面的样品基底，该表面限定了二维样品平面。 该系统包括被配置为向样品基底提供激发光的激发源。 该系统还包括光学检测器，其被配置为接收来自样品基板的发射光并产生检测数据。 该系统还包括扫描头，该扫描头至少配置成（i）将激发光引向样品衬底，（ii）接收来自样品衬底的发射光并将发射光引向光学检测器，以及（iii）用于扫描 相对于样品基底。 所述系统包括至少一个致动器，其构造成相对于样品基板扫描扫描头，所述至少一个致动器被配置为提供以下中的至少一个：（1）相对线性运动和围绕大体垂直的旋转轴线的相对角运动 （2）大致垂直于样品平面的两个不同旋转轴的两个相对角运动。
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公开(公告)号：US20080316482A1
公开(公告)日：2008-12-25
申请号：US12222820
申请日：2008-08-18
IPC分类号： G01N21/64
CPC分类号： G01N21/645 , F21V29/54 , F21V29/677 , F21V29/763 , G01N21/6452 , G01N2021/6439 , G01N2201/062 , G01N2201/1211 , G05D23/1919 , G05D23/20
摘要： Methods and optical systems for scanning of a target sample, including methods and systems using a low mass scan head. The present invention also relates to methods and systems for performing sample assays, and for producing and measuring optical responses and signatures.
摘要翻译： 用于扫描目标样品的方法和光学系统，包括使用低质量扫描头的方法和系统。 本发明还涉及用于进行样品测定以及用于产生和测量光学响应和特征的方法和系统。
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公开(公告)号：US07410793B2
公开(公告)日：2008-08-12
申请号：US10440920
申请日：2003-05-19
CPC分类号： G01N21/6486 , B01L7/52 , C12Q2545/101 , G01N21/6452 , G01N2021/6419 , G01N2021/6421 , G01N2021/6439 , G01N2021/6441 , G01N2021/6463 , G01N2021/6482 , G01N2201/0245 , G01N2201/0628 , G01N2201/0635 , Y10S435/808 , Y10S435/809
摘要： An optical instrument is provided for simultaneously illuminating two or more spaced-apart reaction regions with excitation beams generated by a light source. The light source can include an area light array of light emitting diodes, one or more solid state lasers, one or more micro-wire lasers, or a combination thereof. According to various embodiments, a Fresnel lens can be disposed along a beam bath between the light source and the reaction regions. Methods of analysis using the optical instrument are also provided.
摘要翻译： 提供了一种光学仪器，用于同时用由光源产生的激发光束照射两个或更多个间隔开的反应区域。 光源可以包括发光二极管的区域光阵列，一个或多个固态激光器，一个或多个微线激光器，或其组合。 根据各种实施例，菲涅耳透镜可以沿着光源和反应区域之间的光束槽设置。 还提供了使用光学仪器的分析方法。
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公开(公告)号：US08557569B2
公开(公告)日：2013-10-15
申请号：US12217410
申请日：2008-07-03
CPC分类号： G01N21/6486 , B01L7/52 , C12Q2545/101 , G01N21/6452 , G01N2021/6419 , G01N2021/6421 , G01N2021/6439 , G01N2021/6441 , G01N2021/6463 , G01N2021/6482 , G01N2201/0245 , G01N2201/0628 , G01N2201/0635 , Y10S435/808 , Y10S435/809
摘要： An optical instrument is provided for simultaneously illuminating two or more spaced-apart reaction regions with excitation beams generated by a light source. The light source can include an area light array of light emitting diodes, one or more solid state lasers, one or more micro-wire lasers, or a combination thereof. According to various embodiments, a Fresnel lens can be disposed along a beam bath between the light source and the reaction regions. Methods of analysis using the optical instrument are also provided.
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公开(公告)号：US08492138B2
公开(公告)日：2013-07-23
申请号：US13611462
申请日：2012-09-12
CPC分类号： G01N21/6486 , B01L7/52 , C12Q2545/101 , G01N21/6452 , G01N2021/6419 , G01N2021/6421 , G01N2021/6439 , G01N2021/6441 , G01N2021/6463 , G01N2021/6482 , G01N2201/0245 , G01N2201/0628 , G01N2201/0635 , Y10S435/808 , Y10S435/809
摘要： An optical instrument is provided for simultaneously illuminating two or more spaced-apart reaction regions with excitation beams generated by a light source. The light source can include an area light array of light emitting diodes, one or more solid state lasers, one or more micro-wire lasers, or a combination thereof. According to various embodiments, a Fresnel lens can be disposed along a beam bath between the light source and the reaction regions. Methods of analysis using the optical instrument are also provided.
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公开(公告)号：US20130011848A1
公开(公告)日：2013-01-10
申请号：US13611462
申请日：2012-09-12
CPC分类号： G01N21/6486 , B01L7/52 , C12Q2545/101 , G01N21/6452 , G01N2021/6419 , G01N2021/6421 , G01N2021/6439 , G01N2021/6441 , G01N2021/6463 , G01N2021/6482 , G01N2201/0245 , G01N2201/0628 , G01N2201/0635 , Y10S435/808 , Y10S435/809
摘要： An optical instrument is provided for simultaneously illuminating two or more spaced-apart reaction regions with excitation beams generated by a light source. The light source can include an area light array of light emitting diodes, one or more solid state lasers, one or more micro-wire lasers, or a combination thereof. According to various embodiments, a Fresnel lens can be disposed along a beam bath between the light source and the reaction regions. Methods of analysis using the optical instrument are also provided.
摘要翻译： 提供了一种光学仪器，用于同时用由光源产生的激发光束照射两个或更多个间隔开的反应区域。 光源可以包括发光二极管的区域光阵列，一个或多个固态激光器，一个或多个微线激光器，或其组合。 根据各种实施例，菲涅耳透镜可以沿着光源和反应区域之间的光束槽设置。 还提供了使用光学仪器的分析方法。
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公开(公告)号：US20090009767A1
公开(公告)日：2009-01-08
申请号：US12217410
申请日：2008-07-03
IPC分类号： G01N21/64
CPC分类号： G01N21/6486 , B01L7/52 , C12Q2545/101 , G01N21/6452 , G01N2021/6419 , G01N2021/6421 , G01N2021/6439 , G01N2021/6441 , G01N2021/6463 , G01N2021/6482 , G01N2201/0245 , G01N2201/0628 , G01N2201/0635 , Y10S435/808 , Y10S435/809
摘要： An optical instrument is provided for simultaneously illuminating two or more spaced-apart reaction regions with excitation beams generated by a light source. The light source can include an area light array of light emitting diodes, one or more solid state lasers, one or more micro-wire lasers, or a combination thereof. According to various embodiments, a Fresnel lens can be disposed along a beam bath between the light source and the reaction regions. Methods of analysis using the optical instrument are also provided.
摘要翻译： 提供了一种光学仪器，用于同时用由光源产生的激发光束照射两个或更多个间隔开的反应区域。 光源可以包括发光二极管的区域光阵列，一个或多个固态激光器，一个或多个微线激光器，或其组合。 根据各种实施例，菲涅耳透镜可以沿着光源和反应区域之间的光束槽设置。 还提供了使用光学仪器的分析方法。
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8.发明授权Configurations, systems, and methods for optical scanning with at least one first relative angular motion and at least one second angular motion or at least one linear motion 有权用于具有至少一个第一相对角运动和至少一个第二角运动或至少一个直线运动的光学扫描的配置，系统和方法公开(公告)号：US07423750B2
公开(公告)日：2008-09-09
申请号：US11265110
申请日：2005-11-03
IPC分类号： G01N21/64
CPC分类号： G01N21/645 , F21V29/54 , F21V29/677 , F21V29/763 , G01N21/6452 , G01N2021/6439 , G01N2201/062 , G01N2201/1211 , G05D23/1919 , G05D23/20
摘要： Methods and optical systems for scanning of a target sample, including methods and systems using a low mass scan head and methods and systems for conducting a scanned optically transduced assay where the scanning includes at least one first relative angular motion and at least one second angular motion or at least one linear motion. The present invention also relates to methods and systems for performing sample assays, and for producing and measuring optical responses and signatures.
摘要翻译： 用于扫描靶样品的方法和光学系统，包括使用低质量扫描头的方法和系统，以及用于进行扫描的光学转导测定的方法和系统，其中扫描包括至少一个第一相对角运动和至少一个第二角运动 或至少一个线性运动。 本发明还涉及用于进行样品测定以及用于产生和测量光学响应和特征的方法和系统。
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