公开(公告)号：US20160169999A1

公开(公告)日：2016-06-16

申请号：US14889135

申请日：2010-03-09

申请人： Daniel Alfredo Herza ,  John Andrew Derbyshire

发明人： Daniel Alfredo Herza ,  John Andrew Derbyshire

IPC分类号： G01R33/563 ,  A61B5/0402 ,  G01R33/48 ,  A61B18/20 ,  G01R33/385 ,  G01R33/36 ,  A61B5/0205 ,  A61B5/00

CPC分类号： G01R33/563 ,  A61B5/0205 ,  A61B5/0402 ,  A61B5/055 ,  A61B5/08 ,  A61B5/1102 ,  A61B5/113 ,  A61B5/4836 ,  A61B5/7207 ,  A61B5/7257 ,  A61B5/7285 ,  A61B18/20 ,  A61B2018/00577 ,  A61B2018/00994 ,  A61B2576/00 ,  G01R33/36 ,  G01R33/385 ,  G01R33/4808 ,  G01R33/4824 ,  G01R33/56308 ,  G01R33/56325 ,  G01R33/5676

摘要： A magnetic resonance imaging (MRI) system, comprising a magnetic resonance imaging scanner. The MR scanner comprises a main magnet providing a substantially uniform main magnetic field B0 for a subject under observation, the subject represented by a spatial distribution of magnetizations; a radio frequency (RF) coil system configured to irradiate a plurality of radio frequency (RF) pulses into a region of interest of the subject and to detect a plurality of RF response signals emitted from the region of interest; a gradient coil system configured to provide a perturbation of the main magnetic field B0 using a gradient pulse sequence that causes the RF response signals to encode the spatial distribution of magnetizations in a Fourier domain on a plurality of read-out paths; and a controller in communication with the RF coil system and the gradient coil system to synchronously provide the RF coil system with the plurality of RF pulses and the gradient coil system with the gradient pulse sequence. The gradient pulse sequence comprises a navigator pulse that causes one of the plurality of RF response signals to encode the spatial distribution of magnetizations in the Fourier domain on a pre-determined navigator path that represents a fixed projection of the region of interest of the subject, the pre-determined navigator path is suitable to be in a direction different from directions of the read-out paths, and the fixed projection of the subject is capable of tracking a motion of the subject.

摘要翻译： 磁共振成像（MRI）系统，包括磁共振成像扫描仪。 MR扫描仪包括主磁体，为观察对象提供基本上均匀的主磁场B0，该对象由磁化的空间分布表示; 射频（RF）线圈系统，被配置为将多个射频（RF）脉冲照射到所述对象的感兴趣区域中并且检测从所述感兴趣区域发射的多个RF响应信号; 梯度线圈系统，被配置为使用梯度脉冲序列来提供主磁场B0的扰动，所述梯度脉冲序列使RF响应信号在多个读出路径上的傅立叶域中的磁化空间分布进行编码; 以及与RF线圈系统和梯度线圈系统通信的控制器，以使RF线圈系统与梯度脉冲序列同步地提供多个RF脉冲和梯度线圈系统。 梯度脉冲序列包括导航器脉冲，其导致所述多个RF响应信号中的一个RFF响应信号将傅立叶域中的磁化的空间分布编码在预定导航器路径上，所述预定导航器路径表示所述对象感兴趣区域的固定投影， 预定导航器路径适合于与读出路径的方向不同的方向，并且被摄体的固定投影能够跟踪被摄体的运动。

公开(公告)号：US07253620B1

公开(公告)日：2007-08-07

申请号：US11075415

申请日：2005-03-08

申请人： John Andrew Derbyshire ,  Daniel Alfredo Herzka ,  Elliot R. McVeigh

发明人： John Andrew Derbyshire ,  Daniel Alfredo Herzka ,  Elliot R. McVeigh

IPC分类号： G01V3/00

CPC分类号： G01R33/5613 ,  G01R33/483 ,  G01R33/5602 ,  G01R33/5607

摘要： A method that exploits the intrinsic selectivity of steady-state free precession (SSFP) to perform spectral suppression is disclosed. Such a method avoids the need to incorporate additional spectrally selective pulse sequence elements. The scheme is based on breaking the FISP imaging sequence into short trains having, for example, 8–64 RF pulses. At the moment of echo formation (i.e., TE=TR/2) after the last full RF pulse of the train, water signal is z-stored. Residual transverse magnetization, which include isochromats phase-opposed to the on-resonance water, is gradient crushed and RF spoiled. The stored magnetization is subsequently re-excited with little disturbance to the on-resonance steady-state water signal. The additional time required to perform the steady-state interruption is typically as little as a single TR, minimally affecting the efficiency of the imaging process. The sequence can be employed repetitively, greatly reducing the amplitude of fat signals throughout a real-time or cine imaging process.

摘要翻译： 公开了利用固态自由进动（SSFP）进行光谱抑制的固有选择性的方法。 这种方法避免了需要引入额外的光谱选择性脉冲序列元件。 该方案基于将FISP成像序列分成具有例如8-64个RF脉冲的短列车。 在列车的最后一个完整RF脉冲之后的回波形成时刻（即TE = TR / 2），水信号被z存储。 残留的横向磁化，包括与共振水相反的异色素，是梯度压碎和RF损坏的。 存储的磁化随后再次激发，对谐振稳态水信号几乎没有干扰。 执行稳态中断所需的额外时间通常与单个TR一样少，最小程度上影响成像过程的效率。 该序列可以重复使用，大大降低了实时或电影成像过程中脂肪信号的幅度。

公开(公告)号：US08085041B2

公开(公告)日：2011-12-27

申请号：US12100811

申请日：2008-04-10

申请人： Pelin Aksit ,  John Andrew Derbyshire

发明人： Pelin Aksit ,  John Andrew Derbyshire

IPC分类号： G01V3/00

CPC分类号： G01R33/5616 ,  G01R33/243 ,  G01R33/56554 ,  G01R33/56563

摘要： A system and method for MR magnetic field mapping includes a computer programmed to acquire a first data point at a first location in a first phase image data set, a second data point at the first location in a second phase image data set, a third data point at the first location in a third phase image data set. The first, second, and third phase images are acquired using a first, second, and third TE, respectively. Phase wrapping does not occur among the first and second phase image data sets; however, phase wrapping does occur among the second and third phase image data sets. The computer is also programmed to determine a magnetic field inhomogeneity, wherein the determination of the magnetic field inhomogeneity is based on the first, second, and third data points.

摘要翻译： 用于MR磁场映射的系统和方法包括被编程为在第一相位图像数据集中的第一位置处获取第一数据点的计算机，在第二相位图像数据集中的第一位置处的第二数据点，第三数据 指向第三相图像数据集中的第一位置。 分别使用第一，第二和第三TE获取第一，第二和第三相位图像。 在第一和第二相位图像数据集之间不发生相位缠绕; 然而，相位缠绕确实发生在第二和第三相位图像数据集之间。 计算机还被编程为确定磁场不均匀性，其中磁场不均匀性的确定基于第一，第二和第三数据点。

公开(公告)号：US10371779B2

公开(公告)日：2019-08-06

申请号：US14889135

申请日：2010-03-09

申请人： Daniel Alfredo Herzka ,  John Andrew Derbyshire

发明人： Daniel Alfredo Herzka ,  John Andrew Derbyshire

IPC分类号： G01R33/563 ,  A61B5/055 ,  A61B5/00 ,  G01R33/48 ,  G01R33/567 ,  A61B5/0205 ,  A61B5/0402 ,  A61B18/20 ,  G01R33/36 ,  G01R33/385 ,  A61B5/08 ,  A61B5/11 ,  A61B5/113 ,  A61B18/00

摘要： A magnetic resonance imaging (MRI) system, comprising a magnetic resonance imaging scanner. The MR scanner comprises a main magnet providing a substantially uniform main magnetic field B0 for a subject under observation, the subject represented by a spatial distribution of magnetizations; a radio frequency (RF) coil system configured to irradiate a plurality of radio frequency (RF) pulses into a region of interest of the subject and to detect a plurality of RF response signals emitted from the region of interest; a gradient coil system configured to provide a perturbation of the main magnetic field B0 using a gradient pulse sequence that causes the RF response signals to encode the spatial distribution of magnetizations in a Fourier domain on a plurality of read-out paths; and a controller in communication with the RF coil system and the gradient coil system to synchronously provide the RF coil system with the plurality of RF pulses and the gradient coil system with the gradient pulse sequence. The gradient pulse sequence comprises a navigator pulse that causes one of the plurality of RF response signals to encode the spatial distribution of magnetizations in the Fourier domain on a pre-determined navigator path that represents a fixed projection of the region of interest of the subject, the pre-determined navigator path is suitable to be in a direction different from directions of the read-out paths, and the fixed projection of the subject is capable of tracking a motion of the subject.

公开(公告)号：US07880466B2

公开(公告)日：2011-02-01

申请号：US11751479

申请日：2007-05-21

申请人： John Andrew Derbyshire ,  Daniel Alfredo Herzka ,  Elliot R. McVeigh

发明人： John Andrew Derbyshire ,  Daniel Alfredo Herzka ,  Elliot R. McVeigh

IPC分类号： G01V3/00

CPC分类号： G01R33/5613 ,  G01R33/483 ,  G01R33/5602 ,  G01R33/5607

摘要： A method for fat-suppressed imaging is disclosed. Such a method may include storing a first spectral component of an echo signal formed at TR/2 from a sample, suppressing a second spectral component of the echo signal at TR/2, re-exciting the stored spectral component after suppressing the second spectral component, and producing an image of the sample based on the re-excited stored spectral component.

摘要翻译： 公开了一种脂肪抑制成像方法。 这样的方法可以包括：存储来自样本的在TR / 2处形成的回波信号的第一频谱分量，以TR / 2抑制回波信号的第二频谱分量，在抑制第二频谱分量之后重新激励存储的频谱分量 并且基于重新存储的光谱分量产生样本的图像。

公开(公告)号：US20090256567A1

公开(公告)日：2009-10-15

申请号：US12100811

申请日：2008-04-10

申请人： Pelin Aksit ,  John Andrew Derbyshire

发明人： Pelin Aksit ,  John Andrew Derbyshire

IPC分类号： G01R33/54

CPC分类号： G01R33/5616 ,  G01R33/243 ,  G01R33/56554 ,  G01R33/56563

摘要： A system and method for MR magnetic field mapping includes a computer programmed to acquire a first data point at a first location in a first phase image data set, a second data point at the first location in a second phase image data set, a third data point at the first location in a third phase image data set. The first, second, and third phase images are acquired using a first, second, and third TE, respectively. Phase wrapping does not occur among the first and second phase image data sets; however, phase wrapping does occur among the second and third phase image data sets. The computer is also programmed to determine a magnetic field inhomogeneity, wherein the determination of the magnetic field inhomogeneity is based on the first, second, and third data points.

摘要翻译： 用于MR磁场映射的系统和方法包括被编程为在第一相位图像数据集中的第一位置处获取第一数据点的计算机，在第二相位图像数据集中的第一位置处的第二数据点，第三数据 指向第三相图像数据集中的第一位置。 分别使用第一，第二和第三TE获取第一，第二和第三相位图像。 在第一和第二相位图像数据集之间不发生相位缠绕; 然而，相位缠绕确实发生在第二和第三相位图像数据集之间。 计算机还被编程为确定磁场不均匀性，其中磁场不均匀性的确定基于第一，第二和第三数据点。

公开(公告)号：US06965234B1

公开(公告)日：2005-11-15

申请号：US10960212

申请日：2004-10-06

申请人： Charles H. Cunningham ,  Juan M. Santos ,  John M. Pauly ,  Graham Arnold Wright ,  Jeffrey Alan Stainsby ,  John Andrew Derbyshire

发明人： Charles H. Cunningham ,  Juan M. Santos ,  John M. Pauly ,  Graham Arnold Wright ,  Jeffrey Alan Stainsby ,  John Andrew Derbyshire

IPC分类号： G01R33/46 ,  G01R33/483 ,  G01V3/00

CPC分类号： G01R33/4838 ,  G01R33/4616 ,  G01R33/4833

摘要： A RF Excitation pulse for MRI applications has built-in saturation sidebands, thereby reducing the time for an excitation sequence. The pulse is created using the Shinnar-Le Roux (SLR) transform and designing beta-polynomials for a desired image slice excitation and for saturation of RF excitation such as by de-phasing in regions adjacent to the desired image slice. The beta-polynomials are combined and an inverse SLR transform creates the RF pulse from the combined beta-polynomial.

摘要翻译： 用于MRI应用的RF激励脉冲具有内置饱和边带，从而减少激励序列的时间。 使用Shinnar-Le Roux（SLR）变换创建脉冲，并为期望的图像切片激励设计β多项式，并且通过例如通过在与期望的图像切片相邻的区域中去相位来设置RF激发的饱和度。 β多项式被组合，逆SLR变换从组合的β多项式创建RF脉冲。