公开(公告)号：US09008751B2

公开(公告)日：2015-04-14

申请号：US13305496

申请日：2011-11-28

申请人： Michael Guttman ,  Elliot R. McVeigh

发明人： Michael Guttman ,  Elliot R. McVeigh

IPC分类号： G06T15/08 ,  G01R33/56 ,  G01R33/563

CPC分类号： G06T15/08 ,  G01R33/5608 ,  G01R33/56308

摘要： A method of producing volume renderings from magnetic resonance image data in real time with user interactivity. The method comprises collecting raw magnetic resonance image (MRI) data representative of shapes within an image volume; transferring the raw MRI data to a computer; and continuously producing volume renderings from the raw MRI data in real time with respect to the act of collecting raw MRI data representative of shapes within the image volume.

摘要翻译： 一种利用用户交互性实时地从磁共振图像数据产生体积渲染的方法。 该方法包括收集表示图像体积内的形状的原始磁共振图像（MRI）数据; 将原始MRI数据传输到计算机; 并且相对于收集表示图像体积内的形状的原始MRI数据的动作，实时地从原始MRI数据生成体积效果图。

公开(公告)号：US07375520B2

公开(公告)日：2008-05-20

申请号：US11409511

申请日：2006-04-20

申请人： Reza Nezafat ,  J. Andrew Derbyshire ,  Ronald Ouwerkerk ,  Matthias Stuber ,  Elliot R. McVeigh

发明人： Reza Nezafat ,  J. Andrew Derbyshire ,  Ronald Ouwerkerk ,  Matthias Stuber ,  Elliot R. McVeigh

IPC分类号： G01V3/00

CPC分类号： G01R33/5635 ,  A61B5/0402 ,  A61B5/055 ,  A61B5/7285 ,  G01R33/5602

摘要： A T2 preparation sequence uses a segmented BIR-4 adiabatic pulse with two substantially equal delays and is insensitive to B1 field variations and can simultaneously suppress fat signals with low specific absorption rate (SAR). An adiabatic reverse half passage pulse is applied followed by a predetermined delay. An adiabatic full passage pulse is applied followed by a substantially equal delay, followed by an adiabatic half passage pulse. Fat signal suppression is achieved by increasing or decreasing either the first delay or the second delay.

摘要翻译： 制备序列使用具有两个基本相等的延迟的分段BIR-4绝热脉冲，并且对B＆lt; 1＆gt;场变化不敏感，并且可以同时抑制具有低比吸收率的脂肪信号 （特区）。 施加绝热的反向半通脉冲，然后施加预定的延迟。 施加绝热的全通脉冲，然后施加基本相等的延迟，随后是绝热的半通脉冲。 通过增加或减少第一延迟或第二延迟来实现脂肪信号抑制。

公开(公告)号：US06292684B1

公开(公告)日：2001-09-18

申请号：US09460686

申请日：1999-12-14

申请人： Yiping Du ,  Elliot R. McVeigh

发明人： Yiping Du ,  Elliot R. McVeigh

IPC分类号： A61B5055

CPC分类号： G01R33/5676

摘要： Navigator signals are acquired during a cardiac gated MRI scan to measure the position and velocity components of respiratory motion. Acquired cardiac image views are discarded and/or corrected based on the measurement of the positional and velocity components of respiratory motion to reduce motion artifacts. In one embodiment the navigator pulse sequence includes velocity encoding gradient, and in a second embodiment, velocity is determined by measuring the change in diaphragm position between successive navigator pulse sequences.

摘要翻译： 在心脏门控MRI扫描期间获取导航信号，以测量呼吸运动的位置和速度分量。 基于呼吸运动的位置和速度分量的测量来减少获取的心脏图像视图和/或校正以减少运动伪像。 在一个实施例中，导航器脉冲序列包括速度编码梯度，并且在第二实施例中，通过测量连续导航器脉冲序列之间的隔膜位置的变化来确定速度。

公开(公告)号：US5512825A

公开(公告)日：1996-04-30

申请号：US346130

申请日：1994-11-25

申请人： Ergin Atalar ,  Elliot R. McVeigh

发明人： Ergin Atalar ,  Elliot R. McVeigh

IPC分类号： G01V3/14 ,  A61B5/055 ,  G01R33/385 ,  G01R33/54 ,  G01R33/561 ,  G01V3/00

CPC分类号： G01R33/4833 ,  G01R33/561

摘要： A method of minimizing dead-periods in magnetic resonance imaging pulse sequences employs a specimen disposed within magnetic field, a source of RF signals, a receiver for receiving signals from the specimen responsive to RF pulses and emitting respective output signals. A computer is provided for receiving the output signals from the receiver and establishing image information which may be displayed. For the dead-period, the minimum and maximum phase encoding step, the scan plane gradient pulse for the slice, phase encoding and readout directions are determined and the moments contained within the dead-period waveform is determined. The values are transformed into gradient amplifier coordinates and the minimum dead-period based on a dead-period waveform is determined. The dead-period is employed in establishing a hardware optimized waveform which may be trapezoidal. The trapezoidal waveform is preferably established by for each phase encoding step determining the starting and ending gradient levels and the moments contained within the dead-period waveform and employing the waveform to design a trapezoidal waveform using the calculated minimum dead-period. The method is particularly advantageous when employed in oblique magnetic resonance imaging. The method may also be employed with velocity-encoded or flow-compensated pulse sequences by employing first gradient moments in the information processing, in addition to the starting and ending gradient levels and the zeroeth moments. For other types of pulse sequences, the zeroeth moment and other higher moments may be employed. Associated apparatus is also disclosed.

摘要翻译： 使磁共振成像脉冲序列中的死区最小化的方法使用设置在磁场内的样本，RF信号源，接收器，用于响应于RF脉冲接收来自样本的信号并发射相应的输出信号。 提供一种计算机，用于从接收器接收输出信号并建立可显示的图像信息。 在死区期间，确定最小和最大相位编码步骤，用于切片，相位编码和读出方向的扫描平面梯度脉冲，并且确定包含在死区波形内的力矩。 将这些值转换为梯度放大器坐标，并确定基于死区波形的最小死区。 死区是用来建立可能是梯形的硬件优化波形。 优选地，对于每个相位编码步骤确定梯形波形，确定起始和结束梯度水平以及包含在死区波形内的力矩，并使用该波形来设计使用所计算的最小死区的梯形波形。 该方法在用于倾斜磁共振成像时是特别有利的。 除了开始和结束梯度水平以及零时刻之外，还可以通过在信息处理中采用第一梯度力矩，使用速度编码或流量补偿脉冲序列。 对于其他类型的脉冲序列，可以采用零时刻和其它更高的时刻。 还公开了相关装置。

公开(公告)号：US08068893B2

公开(公告)日：2011-11-29

申请号：US10076882

申请日：2002-02-14

申请人： Michael Guttman ,  Elliot R. McVeigh

发明人： Michael Guttman ,  Elliot R. McVeigh

IPC分类号： A61B5/05

CPC分类号： G06T15/08 ,  G01R33/5608 ,  G01R33/56308

摘要： A method of producing volume renderings from magnetic resonance image data in real time with user interactivity. The method comprises collecting raw magnetic resonance image (MRI) data representative of shapes within an image volume; transferring the raw MRI data to a computer; and continuously producing volume renderings from the raw MRI data in real time with respect to the act of collecting raw MRI data representative of shapes within the image volume.

摘要翻译： 一种利用用户交互性实时地从磁共振图像数据产生体积渲染的方法。 该方法包括收集表示图像体积内的形状的原始磁共振图像（MRI）数据; 将原始MRI数据传输到计算机; 并且相对于收集表示图像体积内的形状的原始MRI数据的动作，实时地从原始MRI数据生成体积效果图。

公开(公告)号：US07285954B2

公开(公告)日：2007-10-23

申请号：US11227406

申请日：2005-09-14

申请人： Reza Nezafat ,  Richard B. Thompson ,  Elliot R. McVeigh

发明人： Reza Nezafat ,  Richard B. Thompson ,  Elliot R. McVeigh

IPC分类号： G01V3/00

CPC分类号： G01R33/56308 ,  G01R33/4824 ,  G01R33/561 ,  G01R33/56316

摘要： Phase contrast magnetic resonance images are produced using interleaved spiral k-space scanning with a bipolar phase contrast gradient. Spiral scanning is configured so that acquisition impulse response defines a central alias free portion in a partial field of view, and signal acquisition is arranged so that moving spins are contained with this central alias free portion. First and second signals are acquired with alternate phase encodings, and a complex difference of the acquired signals is obtained. The complex difference is substantially free of aliasing artifacts within the central portion.

公开(公告)号：US07253620B1

公开(公告)日：2007-08-07

申请号：US11075415

申请日：2005-03-08

申请人： John Andrew Derbyshire ,  Daniel Alfredo Herzka ,  Elliot R. McVeigh

发明人： John Andrew Derbyshire ,  Daniel Alfredo Herzka ,  Elliot R. McVeigh

IPC分类号： G01V3/00

CPC分类号： G01R33/5613 ,  G01R33/483 ,  G01R33/5602 ,  G01R33/5607

摘要： A method that exploits the intrinsic selectivity of steady-state free precession (SSFP) to perform spectral suppression is disclosed. Such a method avoids the need to incorporate additional spectrally selective pulse sequence elements. The scheme is based on breaking the FISP imaging sequence into short trains having, for example, 8–64 RF pulses. At the moment of echo formation (i.e., TE=TR/2) after the last full RF pulse of the train, water signal is z-stored. Residual transverse magnetization, which include isochromats phase-opposed to the on-resonance water, is gradient crushed and RF spoiled. The stored magnetization is subsequently re-excited with little disturbance to the on-resonance steady-state water signal. The additional time required to perform the steady-state interruption is typically as little as a single TR, minimally affecting the efficiency of the imaging process. The sequence can be employed repetitively, greatly reducing the amplitude of fat signals throughout a real-time or cine imaging process.

摘要翻译： 公开了利用固态自由进动（SSFP）进行光谱抑制的固有选择性的方法。 这种方法避免了需要引入额外的光谱选择性脉冲序列元件。 该方案基于将FISP成像序列分成具有例如8-64个RF脉冲的短列车。 在列车的最后一个完整RF脉冲之后的回波形成时刻（即TE = TR / 2），水信号被z存储。 残留的横向磁化，包括与共振水相反的异色素，是梯度压碎和RF损坏的。 存储的磁化随后再次激发，对谐振稳态水信号几乎没有干扰。 执行稳态中断所需的额外时间通常与单个TR一样少，最小程度上影响成像过程的效率。 该序列可以重复使用，大大降低了实时或电影成像过程中脂肪信号的幅度。

公开(公告)号：US07155271B2

公开(公告)日：2006-12-26

申请号：US10424093

申请日：2003-04-28

申请人： Henry R. Halperin ,  Ronald D. Berger ,  Ergin Atalar ,  Elliot R. McVeigh ,  Albert Lardo ,  Hugh Calkins ,  Joao Lima

发明人： Henry R. Halperin ,  Ronald D. Berger ,  Ergin Atalar ,  Elliot R. McVeigh ,  Albert Lardo ,  Hugh Calkins ,  Joao Lima

IPC分类号： A61B5/055

CPC分类号： A61B5/055 ,  A61B5/415 ,  A61B5/418 ,  A61B18/1492 ,  A61B90/36 ,  A61B2017/00039 ,  A61B2017/00053 ,  A61B2090/374 ,  G01R33/285 ,  G01R33/34084 ,  G01R33/4808 ,  G01R33/5601

摘要： A system and method for using magnetic resonance imaging to increase the accuracy of electrophysiologic procedures is disclosed. The system in its preferred embodiment provides an invasive combined electrophysiology and imaging antenna catheter which includes an RF antenna for receiving magnetic resonance signals and diagnostic electrodes for receiving electrical potentials. The combined electrophysiology and imaging antenna catheter is used in combination with a magnetic resonance imaging scanner to guide and provide visualization during electrophysiologic diagnostic or therapeutic procedures. The invention is particularly applicable to catheter ablation, e.g., ablation of atrial fibrillation. In embodiments which are useful for catheter ablation, the combined electrophysiology and imaging antenna catheter may further include an ablation tip, and such embodiment may be used as an intracardiac device to both deliver energy to selected areas of tissue and visualize the resulting ablation lesions, thereby greatly simplifying production of continuous linear lesions. The invention further includes embodiments useful for guiding electrophysiologic diagnostic and therapeutic procedures other than ablation. Imaging of ablation lesions may be further enhanced by use of MR contrast agents. The antenna utilized in the combined electrophysiology and imaging catheter for receiving MR signals is preferably of the coaxial or “loopless” type. High-resolution images from the antenna may be combined with low-resolution images from surface coils of the MR scanner to produce a composite image. The invention further provides a system for eliminating the pickup of RF energy in which intracardiac wires are detuned by filtering so that they become very inefficient antennas. An RF filtering system is provided for suppressing the MR imaging signal while not attenuating the RF ablative current. Steering means may be provided for steering the invasive catheter under MR guidance. Other ablative methods can be used such as laser, ultrasound, and low temperatures.

公开(公告)号：US06171241B2

公开(公告)日：2001-01-09

申请号：US09095910

申请日：1998-06-11

申请人： Elliot R. McVeigh ,  Bradley D. Bolster, Jr.

发明人： Elliot R. McVeigh ,  Bradley D. Bolster, Jr.

IPC分类号： A61B5055

CPC分类号： A61B5/1128 ,  A61B5/055 ,  A61B5/7257 ,  G01R33/563 ,  G01R33/56333 ,  G01R33/5673

摘要： A method of magnetic resonance imaging of myocardial motion includes positioning a portion of a patient such as a patient's heart within a main magnetic field and employing a plurality of RF signals to establish a plurality of parallel plane tags through the portion. In imaging heart motion, a first minimum spacing between adjacent tags is employed in a region where the tags will decrease their separation over systole and a second initial tag separation will be employed for portions wherein the tags increase their separation over systole. The method facilitates simultaneous imaging of both such motions. Fourier coefficients may be employed in establishing the generally parallel tags which may be positioned generally symmetrically about a central tag.

摘要翻译： 心肌运动的磁共振成像的方法包括将病人心脏的一部分患者定位在主磁场内，并采用多个RF信号，以通过该部分建立多个平行平面标签。 在成像心脏运动中，相邻标签之间的第一最小间距用于标签将减小其在收缩期上的分离的区域，并且第二初始标签分离将用于其中标签增加其与收缩期分离的部分。 该方法有助于同时成像这两种运动。 可以采用傅里叶系数来建立大致平行的标签，其可以围绕中心标签大致对称地定位。

公开(公告)号：US07822460B2

公开(公告)日：2010-10-26

申请号：US11924877

申请日：2007-10-26

申请人： Henry R. Halperin ,  Ronald D. Berger ,  Ergin Atalar ,  Elliot R. McVeigh ,  Albert Lardo ,  Hugh Calkins ,  Joao Lima

发明人： Henry R. Halperin ,  Ronald D. Berger ,  Ergin Atalar ,  Elliot R. McVeigh ,  Albert Lardo ,  Hugh Calkins ,  Joao Lima

IPC分类号： A61B5/05 ,  G01V3/00

CPC分类号： A61B5/055 ,  A61B5/415 ,  A61B5/418 ,  A61B18/1492 ,  A61B90/36 ,  A61B2017/00039 ,  A61B2017/00053 ,  A61B2090/374 ,  G01R33/285 ,  G01R33/34084 ,  G01R33/4808 ,  G01R33/5601

摘要： A system and method for using magnetic resonance imaging to increase the accuracy of electrophysiologic procedures is disclosed. The system in its preferred embodiment provides an invasive combined electrophysiology and imaging antenna catheter which includes an RF antenna for receiving magnetic resonance signals and diagnostic electrodes for receiving electrical potentials. The combined electrophysiology and imaging antenna catheter is used in combination with a magnetic resonance imaging scanner to guide and provide visualization during electrophysiologic diagnostic or therapeutic procedures. The invention further provides a system for eliminating the pickup of RF energy in which intracardiac wires are detuned by filtering so that they become very inefficient antennas. An RF filtering system is provided for suppressing the MR imaging signal while not attenuating the RF ablative current. Steering means may be provided for steering the invasive catheter under MR guidance.

摘要翻译： 公开了一种使用磁共振成像来提高电生理过程精度的系统和方法。 该系统在其优选实施例中提供了一种侵入性组合电生理学和成像天线导管，其包括用于接收磁共振信号的RF天线和用于接收电位的诊断电极。 组合的电生理和成像天线导管与磁共振成像扫描仪结合使用以在电生理诊断或治疗过程中引导和提供可视化。 本发明还提供一种用于消除射频能量的拾取的系统，其中心内线通过滤波失谐，使得它们变得非常低效的天线。 提供RF滤波系统，用于抑制MR成像信号，同时不衰减RF消融电流。 可以提供转向装置用于在MR引导下转导侵入性导管。