公开(公告)号：US20100049030A1

公开(公告)日：2010-02-25

申请号：US12194963

申请日：2008-08-20

申请人： John K. Saunders ,  David Graves ,  Gordon Scarth

发明人： John K. Saunders ,  David Graves ,  Gordon Scarth

IPC分类号： A61B5/05

CPC分类号： A61N5/1049 ,  A61N5/1067 ,  A61N2005/1055 ,  G01R33/381 ,  G01R33/4808 ,  G01R33/5673

摘要： Radiation therapy of a lesion within a patient is guided to take into account movement of the lesion caused by respiration and/or cardiac effects by using MRI to image the patient while on the treatment support to obtain a series of images of a location of the lesion within the patient while obtaining data relating to respiration and/or cardiac function of the patient to generate lesion movement data as a function of respiration and/or cardiac function. After the magnet is removed from the bunker, during the radiation therapy, real time data relating to respiration and/or cardiac function of the patient is used to guide the radiation therapy using the lesion movement data obtained during the imaging.

摘要翻译： 指导患者内的病变的放射治疗以考虑由呼吸和/或心脏作用引起的病变的移动，其中在治疗支持下使用MRI对患者进行成像以获得病变位置的一系列图像 在获得与患者的呼吸和/或心脏功能相关的数据以产生作为呼吸和/或心脏功能的函数的病变运动数据的患者内。 在磁体从掩体中取出之后，在放射治疗期间，使用与患者的呼吸和/或心脏功能有关的实时数据来引导使用在成像期间获得的损伤运动数据的放射治疗。

公开(公告)号：US08073524B2

公开(公告)日：2011-12-06

申请号：US11936881

申请日：2007-11-08

申请人： John K. Saunders ,  Lindley Ward ,  Gordon Scarth

发明人： John K. Saunders ,  Lindley Ward ,  Gordon Scarth

IPC分类号： A61B5/05

CPC分类号： G01R33/3875 ,  G01R33/3815 ,  G01R33/481 ,  G01R33/4812

摘要： A patient imaging system includes a patient support table and an MRI system including a cylindrical magnet. The magnet defines a cylindrical bore for receiving the patient on the table where the magnet is mounted for rotation about a vertical axis on a slew ring carried on rails allowing longitudinal movement. The magnet is arranged in a two or three room diagnostic configuration in which a holding bay houses the magnet and the diagnostic patients are organized in the three rooms each cooperating with the magnet bay. A control system is provided for inputting data defining different locations or conditions of the magnet relative to its environment and for each of the different conditions data is stored defining a respective set of shimming parameters so that the control system automatically inputs the shimming parameters and adjusts the shimming as the magnet is moved or a secondary imaging system is brought up to the magnet.

摘要翻译： 患者成像系统包括患者支撑台和包括圆柱形磁体的MRI系统。 磁体限定了一个圆柱形孔，用于接收患者在桌子上，磁铁被安装成围绕允许纵向运动的轨道上承载的回转环上的垂直轴线旋转。 磁体布置在两个或三个房间诊断配置中，其中保持舱容纳磁体，并且诊断患者组织在与磁体舱相配合的三个房间中。 提供控制系统用于输入定义磁体相对于其环境的不同位置或条件的数据，并且对于不同条件中的每一个，存储数据，其中定义相应的垫片参数集合，使得控制系统自动输入匀场参数并调整 当磁体移动时，垫片或二次成像系统被带到磁体上。

公开(公告)号：US20090124884A1

公开(公告)日：2009-05-14

申请号：US11936881

申请日：2007-11-08

申请人： John K. Saunders ,  Lindley Ward ,  Gordon Scarth

发明人： John K. Saunders ,  Lindley Ward ,  Gordon Scarth

IPC分类号： A61B5/05

CPC分类号： G01R33/3875 ,  G01R33/3815 ,  G01R33/481 ,  G01R33/4812

摘要： A patient imaging system includes a patient support table and an MRI system including a cylindrical magnet. The magnet defines a cylindrical bore for receiving the patient on the table where the magnet is mounted for rotation about a vertical axis on a slew ring carried on rails allowing longitudinal movement. The magnet is arranged in a two or three room diagnostic configuration in which a holding bay houses the magnet and the diagnostic patients are organized in the three rooms each cooperating with the magnet bay. A control system is provided for inputting data defining different locations or conditions of the magnet relative to its environment and for each of the different conditions data is stored defining a respective set of shimming parameters so that the control system automatically inputs the shimming parameters and adjusts the shimming as the magnet is moved or a secondary imaging system is brought up to the magnet.

摘要翻译： 患者成像系统包括患者支撑台和包括圆柱形磁体的MRI系统。 磁体限定了一个圆柱形孔，用于接收患者在桌子上，磁铁被安装成围绕允许纵向运动的轨道上承载的回转环上的垂直轴线旋转。 磁体布置在两个或三个房间诊断配置中，其中保持舱容纳磁体，并且诊断患者组织在与磁体舱相配合的三个房间中。 提供控制系统用于输入定义磁体相对于其环境的不同位置或条件的数据，并且对于不同条件中的每一个，存储数据，其中定义相应的垫片参数集合，使得控制系统自动输入匀场参数并调整 当磁体移动时，垫片或二次成像系统被带到磁体上。

公开(公告)号：US20120190966A1

公开(公告)日：2012-07-26

申请号：US13040037

申请日：2011-03-03

申请人： Shawn Schaerer ,  Mark Alexiuk ,  Gord Scarth ,  John K. Saunders ,  Meir Dahan

发明人： Shawn Schaerer ,  Mark Alexiuk ,  Gord Scarth ,  John K. Saunders ,  Meir Dahan

IPC分类号： A61B5/055

CPC分类号： A61B5/0064 ,  A61B5/0035 ,  A61B5/0071 ,  A61B5/055 ,  A61B5/7425 ,  A61B34/30 ,  A61B90/37 ,  G01R33/4808

摘要： In an MR guided surgical system which is carried out in the bore of an MR magnet and uses fluorescence to detect tumor cells, there is provided a microscope system for viewing the required part of a patient which includes stereoscopic viewing components arranged for use in generating 2D and 3D images displayed to the surgeon. The optical assembly is adjustable to change the view and the visual images are overlaid by the MR images. The visual image can be adjusted in response to movement of the surgical tool and the MR image displayed and/or the image obtained can be modified in response to change in the visual image and/or movement of the tool. The components in the bore are made compatible with the MR environment. A fluorescence delivery system is operated to automatically activate the delivery system in response to detection of the level of fluorescence.

摘要翻译： 在MR导引手术系统中，其在MR磁体的孔中进行并使用荧光来检测肿瘤细胞，提供了一种用于观察患者所需部分的显微镜系统，其包括布置用于生成2D的立体观察组件 并向外科医生显示3D图像。 光学组件是可调节的，以改变视野，并且可视图像被MR图像覆盖。 可以响应于手术工具的移动和显示的MR图像来调整视觉图像，和/或可以响应于视觉图像的变化和/或工具的移动来修改获得的图像。 孔中的组件与MR环境兼容。 操作荧光传递系统以响应于荧光水平的检测来自动激活递送系统。

公开(公告)号：US07834270B2

公开(公告)日：2010-11-16

申请号：US12168200

申请日：2008-07-07

申请人： Haoqin Zhu ,  Jonathan Li ,  John K. Saunders

发明人： Haoqin Zhu ,  Jonathan Li ,  John K. Saunders

IPC分类号： H01B9/02

CPC分类号： H01B11/1895

摘要： Signals in an RF field, such as that of an MRI system, are communicated through an inner conductor having an outer shield with a dielectric material therebetween and an outer cable jacket. Current in the shield caused by the RF field from the transmit body coil is reduced by providing a second dielectric material around the shield conductor and a plurality of segmented shield conductor portions formed of non-magnetic braid or wrapped non-magnetic foil tape outside the second dielectric material and inside the jacket at spaced positions along the cable, with the portions being electrically separated from each other and from the shield so that the segmented shield conductor portions act to shield the outer shield conductor to reduce the generation of current thereon while the electrical separation of the segmented shield conductor portions each from the others prevents the generation of a current along the portions.

摘要翻译： 在RF场中的信号，例如MRI系统的信号通过具有外屏蔽的内部导体与其间的介电材料和外部电缆护套相连通。 通过在屏蔽导体周围设置第二电介质材料和由非磁性编织物或包裹的非磁性箔带形成的多个分段的屏蔽导体部分，减少了由发射体线圈的RF场引起的屏蔽电流 电介质材料，并且在护套内部沿着电缆的间隔位置，其中部分彼此电隔离并与屏蔽件分开，使得分隔的屏蔽导体部分用于屏蔽外屏蔽导体，以减少其上的电流的产生，同时电 分割的屏蔽导体部分彼此分离防止沿着部分产生电流。

公开(公告)号：US5735278A

公开(公告)日：1998-04-07

申请号：US616737

申请日：1996-03-15

申请人： David Hoult ,  John K. Saunders ,  Garnette Roy Sutherland ,  Franklin A. Roberts

发明人： David Hoult ,  John K. Saunders ,  Garnette Roy Sutherland ,  Franklin A. Roberts

IPC分类号： A61B5/055 ,  A61B17/00 ,  A61B19/00 ,  A61G13/10 ,  G01R33/28 ,  G01R33/38

CPC分类号： G01R33/3802 ,  A61B6/0485 ,  A61B90/00 ,  A61B17/00 ,  G01R33/3806

摘要： Apparatus is provided for use in surgical procedures comprising an operating table for receiving a patient for surgery and a magnetic resonance imaging system for obtaining images of a part of the patient at a series of times through the surgical procedure for analysis by the surgical team to allow the surgical team to monitor the progress of the surgery. The high field magnet and the operating table are shaped and arranged for positioning of the part of the patient into the magnetic field while the patient remains in place on the table and the magnet is mounted for movement between a first position spaced from the table and the patient thereon to allow the surgical team to carry out the surgical procedure and a second position for applying the magnetic field to the part of the patient. The table remains substantially stationary and only the magnet is moved to a position spaced from an adjacent end of the table to allow the surgical team to move around the adjacent end of table and to each side of the table to access the patient.

摘要翻译： 提供了用于外科手术的装置，其包括用于接收手术患者的手术台和用于通过外科手术用于通过外科手术组进行分析的一系列时间获得患者部分的图像的磁共振成像系统，以允许 手术队监测手术进展。 高场磁体和操作台被成形和布置成用于将患者的一部分定位在磁场中，同时患者保持在桌子上的适当位置，并且安装磁体以在与工作台间隔开的第一位置和 患者在其上以允许外科手术组执行外科手术，以及用于将磁场施加到患者部分的第二位置。 桌子基本上保持静止，只有磁铁移动到与桌子的相邻端隔开的位置，以允许外科手术组围绕桌子的相邻端移动到桌子的每一侧以接近病人。

公开(公告)号：US08295906B2

公开(公告)日：2012-10-23

申请号：US12194963

申请日：2008-08-20

申请人： John K. Saunders ,  David Graves ,  Gordon Scarth

发明人： John K. Saunders ,  David Graves ,  Gordon Scarth

IPC分类号： A61B5/055

CPC分类号： A61N5/1049 ,  A61N5/1067 ,  A61N2005/1055 ,  G01R33/381 ,  G01R33/4808 ,  G01R33/5673

摘要： Radiation therapy of a lesion within a patient is guided to take into account movement of the lesion caused by respiration and/or cardiac effects by using MRI to image the patient while on the treatment support to obtain a series of images of a location of the lesion within the patient while obtaining data relating to respiration and/or cardiac function of the patient to generate lesion movement data as a function of respiration and/or cardiac function. After the magnet is removed from the bunker, during the radiation therapy, real time data relating to respiration and/or cardiac function of the patient is used to guide the radiation therapy using the lesion movement data obtained during the imaging.

摘要翻译： 指导患者内的病变的放射治疗以考虑由呼吸和/或心脏作用引起的病变的移动，其中在治疗支持下使用MRI对患者进行成像以获得病变位置的一系列图像 在获得与患者的呼吸和/或心脏功能相关的数据以产生作为呼吸和/或心脏功能的函数的病变运动数据的患者内。 在磁体从掩体中取出之后，在放射治疗期间，使用与患者的呼吸和/或心脏功能有关的实时数据来引导使用在成像期间获得的损伤运动数据的放射治疗。

公开(公告)号：US20120190965A1

公开(公告)日：2012-07-26

申请号：US13012164

申请日：2011-01-24

申请人： Shawn Schaerer ,  Mark Alexiuk ,  Gord Scarth ,  John K. Saunders ,  Meir Dahan

发明人： Shawn Schaerer ,  Mark Alexiuk ,  Gord Scarth ,  John K. Saunders ,  Meir Dahan

IPC分类号： A61B5/055

CPC分类号： A61B5/0059 ,  A61B5/0035 ,  A61B5/055 ,  A61B5/7425 ,  G01R33/4808

摘要： In an MR guided surgical system which is carried out in the bore of an MR magnet, there is provided a microscope system for viewing the required part of a patient which includes stereoscopic viewing components arranged for use in generating 2D and 3D images displayed to the surgeon. The optical assembly is adjustable to change the view and the visual images are overlaid by the MR images. The visual image can be adjusted in response to movement of the surgical tool and the MR image displayed and/or the image obtained can be modified in response to change in the visual image and/or movement of the tool. The components in the bore are made compatible with the MR environment.

摘要翻译： 在MR磁铁的孔中进行的MR引导外科系统中，提供了一种用于观察患者所需部位的显微镜系统，其包括布置用于产生显示给外科医生的2D和3D图像的立体观察组件 。 光学组件是可调节的，以改变视野，并且可视图像被MR图像覆盖。 可以响应于手术工具的移动和显示的MR图像来调整视觉图像，和/或可以响应于视觉图像的变化和/或工具的移动来修改获得的图像。 孔中的组件与MR环境兼容。

公开(公告)号：US20090209848A1

公开(公告)日：2009-08-20

申请号：US12034002

申请日：2008-02-20

申请人： John K. Saunders ,  Stephen G. Hushek ,  Victoria D.M. Hornblower

发明人： John K. Saunders ,  Stephen G. Hushek ,  Victoria D.M. Hornblower

IPC分类号： A61B5/055

CPC分类号： A61B5/0555

摘要： In MR imaging of a body part of a patient in an intra-operative procedure, the body part is supported using gel pads where the gel material is arranged such that the presence of the gel material does not generate an image in the analysis of the RF signal from the location so that the pad is invisible in the MR image. This can be obtained by using a water based gel material and providing an additive such as manganese chloride to reduce the relaxation time of the water molecules to a value which is sufficiently short that the molecules relax before the acquisition of the signals by the RF receive coil. This can be achieved by using a non-water based gel or a heavy water based gel.

摘要翻译： 在术中手术中患者的身体部位的MR成像中，使用凝胶材料布置使得凝胶材料的存在使得在RF分析中不产生图像的凝胶垫来支撑身体部分 信号，使得该垫在MR图像中不可见。 这可以通过使用水基凝胶材料和提供添加剂如氯化锰来获得，以将水分子的松弛时间减小到在RF接收线圈获取信号之前使分子松弛的值足够短 。 这可以通过使用非水基凝胶或重水基凝胶来实现。

公开(公告)号：US20110160566A1

公开(公告)日：2011-06-30

申请号：US12972726

申请日：2010-12-20

申请人： Labros Petropoulos ,  John K. Saunders

发明人： Labros Petropoulos ,  John K. Saunders

IPC分类号： A61B5/055

CPC分类号： G01R33/4814 ,  A61B8/00 ,  A61B8/08 ,  A61B8/4245 ,  A61B8/4254 ,  A61B8/4416 ,  A61B90/37 ,  A61B2017/3405 ,  A61B2017/3413 ,  A61B2090/364 ,  A61B2090/374 ,  A61B2090/376 ,  A61B2090/378 ,  A61N5/1049 ,  A61N5/1067 ,  A61N2005/1055 ,  A61N2005/1058 ,  G01R33/3415 ,  G01R33/4808

摘要： A method is provided for guiding a procedure on a region of interest in a body part of patient, where the body part moves within the patient by breathing, cardiac or other action. The procedure includes radiation therapy, or guidance of a probe for example for biopsy or brachytherapy. The method includes using an MRI system to obtain an MR image of the body part, during the procedure on the body part of the patient, obtaining real time ultrasound images of the body part of the patient as the body part moves within the body of the patient, registering the MR image of the body part with the ultrasound image of the body part so as to locate the region of interest in the ultrasound image of the body part and using the registered images to target the action to the region of interest as the body part moves.

摘要翻译： 提供了一种用于引导患者身体部位的感兴趣区域的过程的方法，其中身体部位通过呼吸，心脏或其他动作在患者体内移动。 该程序包括放射治疗或探针的指导，例如用于活组织检查或近距离放射治疗。 该方法包括使用MRI系统来获得身体部位的MR图像，在患者的身体部位的过程期间，当身体部分在身体内移动时获得患者的身体部分的实时超声图像 患者，用身体部位的超声图像登记身体部位的MR图像，以便将感兴趣的区域定位在身体部位的超声图像中，并且使用注册的图像来将动作定位到感兴趣的区域作为 身体部位移动。