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公开(公告)号:US08708948B2
公开(公告)日:2014-04-29
申请号:US13401803
申请日:2012-02-21
申请人: Paul Consigny , Gabriel Asongwe , Mary Beth Michaels , Gene Michal , Evgenia Mandrusov , Jeong Lee , Florian N. Ludwig , John Eric Henckel , Joseph J. Sciacca , Ken Bueche , Richard Todd Thornton , Fidel Albert Urrabazo , Daniel Wiegand
发明人: Paul Consigny , Gabriel Asongwe , Mary Beth Michaels , Gene Michal , Evgenia Mandrusov , Jeong Lee , Florian N. Ludwig , John Eric Henckel , Joseph J. Sciacca , Ken Bueche , Richard Todd Thornton , Fidel Albert Urrabazo , Daniel Wiegand
CPC分类号: A61K38/18 , A61K35/545 , A61K38/19 , A61K2300/00
摘要: Engraftment of therapeutic cells and agents to a target site in an organism is enhanced by mechanical, chemical and biological methods and systems.
摘要翻译: 通过机械,化学和生物学方法和系统,将治疗细胞和药剂移植到生物体的靶位点。
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公开(公告)号:US20120148668A1
公开(公告)日:2012-06-14
申请号:US13401803
申请日:2012-02-21
申请人: Paul Consigny , Gabriel Asongwe , Mary Beth Michaels , Gene Michal , Evgenia Mandrusov , Jeong Lee , Florian Ludwig , John Eric Henckel , Joseph J. Sciacca , Ken Bueche , Richard Todd Thornton , Fidel Albert Urrabazo , Daniel Wiegand
发明人: Paul Consigny , Gabriel Asongwe , Mary Beth Michaels , Gene Michal , Evgenia Mandrusov , Jeong Lee , Florian Ludwig , John Eric Henckel , Joseph J. Sciacca , Ken Bueche , Richard Todd Thornton , Fidel Albert Urrabazo , Daniel Wiegand
CPC分类号: A61K38/18 , A61K35/545 , A61K38/19 , A61K2300/00
摘要: Engraftment of therapeutic cells and agents to a target site in an organism is enhanced by mechanical, chemical and biological methods and systems.
摘要翻译: 通过机械,化学和生物学方法和系统,将治疗细胞和药剂移植到生物体的靶位点。
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公开(公告)号:US20120064098A1
公开(公告)日:2012-03-15
申请号:US13299341
申请日:2011-11-17
申请人: Paul Consigny , Gabriel Asongwe , Mary Beth Michaels , Gene Michal , Evgenia Mandrusov , Jeong Lee , Florian Ludwig , John Eric Henckel , Joseph J. Sciacca , Ken Bueche , Richard Todd Thornton , Fidel Albert Urrabazo , Daniel Wiegand
发明人: Paul Consigny , Gabriel Asongwe , Mary Beth Michaels , Gene Michal , Evgenia Mandrusov , Jeong Lee , Florian Ludwig , John Eric Henckel , Joseph J. Sciacca , Ken Bueche , Richard Todd Thornton , Fidel Albert Urrabazo , Daniel Wiegand
IPC分类号: A61K47/48
CPC分类号: A61K38/18 , A61K35/545 , A61K38/19 , A61K2300/00
摘要: Engraftment of therapeutic cells and agents to a target site in an organism is enhanced by mechanical, chemical and biological methods and systems.
摘要翻译: 通过机械,化学和生物学方法和系统,将治疗细胞和药剂移植到生物体的靶位点。
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公开(公告)号:US20120157751A1
公开(公告)日:2012-06-21
申请号:US13401790
申请日:2012-02-21
申请人: Paul Consigny , Gabriel Asongwe , Mary Beth Michaels , Gene Michal , Evgenia Mandrusov , Jeong Lee , Florian Ludwig , John Eric Henckel , Joseph J. Sciacca , Ken Bueche , Richard Todd Thornton , Fidel Albert Urrabazo , Daniel Wiegand
发明人: Paul Consigny , Gabriel Asongwe , Mary Beth Michaels , Gene Michal , Evgenia Mandrusov , Jeong Lee , Florian Ludwig , John Eric Henckel , Joseph J. Sciacca , Ken Bueche , Richard Todd Thornton , Fidel Albert Urrabazo , Daniel Wiegand
CPC分类号: A61K38/18 , A61K35/545 , A61K38/19 , A61K2300/00
摘要: Engraftment of therapeutic cells and agents to a target site in an organism is enhanced by mechanical, chemical and biological methods and systems.
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公开(公告)号:US20120148609A1
公开(公告)日:2012-06-14
申请号:US13401796
申请日:2012-02-21
申请人: Paul Consigny , Gabriel Asongwe , Mary Beth Michaels , Gene Michal , Evgenia Mandrusov , Jeong Lee , Florian Ludwig , John Eric Henckel , Joseph J. Sciacca , Ken Bueche , Richard Todd Thornton , Fidel Albert Urrabazo , Daniel Wiegand
发明人: Paul Consigny , Gabriel Asongwe , Mary Beth Michaels , Gene Michal , Evgenia Mandrusov , Jeong Lee , Florian Ludwig , John Eric Henckel , Joseph J. Sciacca , Ken Bueche , Richard Todd Thornton , Fidel Albert Urrabazo , Daniel Wiegand
IPC分类号: A61K35/12 , A61P43/00 , A61K39/395
CPC分类号: A61K38/18 , A61K35/545 , A61K38/19 , A61K2300/00
摘要: Engraftment of therapeutic cells and agents to a target site in an organism is enhanced by mechanical, chemical and biological methods and systems.
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公开(公告)号:US07901613B2
公开(公告)日:2011-03-08
申请号:US12652185
申请日:2010-01-05
IPC分类号: B29C70/72
CPC分类号: B29C70/72
摘要: A vacuum mandrel for use in fabricating an implantable electrode comprises a hollow body member and a first groove provided radially on an outer surface of the hollow body member. The first groove is adapted to receive an implantable electrode and retain the electrode in place with a vacuum pressure during an elastomeric encapsulation of the electrode. The vacuum mandrel further comprises a vacuum port provided in the first groove.
摘要翻译: 用于制造可植入电极的真空心轴包括中空本体构件和径向设置在中空本体构件的外表面上的第一凹槽。 第一凹槽适于接收可植入电极,并且在电极的弹性体封装期间以真空压力将电极保持在适当的位置。 真空心轴还包括设置在第一凹槽中的真空口。
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公开(公告)号:US08509914B2
公开(公告)日:2013-08-13
申请号:US11261102
申请日:2005-10-28
IPC分类号: A61N1/05
CPC分类号: A61N1/0551 , A61N1/0556 , A61N1/0558
摘要: A lead assembly comprises an outer body tubing, first and second conductors, and first and second tubing insert members. The outer body tubing comprises at least two longitudinal outer body tubing portions, each such portion comprising a through-hole and each portion comprising a keyed surface having a predetermined shape. Each of the tubing insert members receives a conductor and comprises a surface that substantially matches the predetermined shape of the keyed surface. When both of the conductors are inserted into corresponding longitudinal through-holes such that each of said first and second surfaces of the first and second hollow body members is substantially aligned with the keyed surface of a corresponding outer body tubing portion, electrodes formed on ends of the first and second conductors are encouraged to be substantially co-linear.
摘要翻译: 引线组件包括外体管,第一和第二导体以及第一和第二管插入件。 外部主体管道包括至少两个纵向外部主体管道部分,每个这样的部分包括通孔,并且每个部分包括具有预定形状的键合表面。 每个管道插入件接收一个导体并且包括一个基本上与键合表面的预定形状匹配的表面。 当两个导体插入到相应的纵向通孔中时,使得第一和第二中空本体构件的所述第一和第二表面中的每一个基本上与相应的外管体部分的键合表面对准, 鼓励第一和第二导体基本上是共线的。
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公开(公告)号:US20100101944A1
公开(公告)日:2010-04-29
申请号:US12652185
申请日:2010-01-05
CPC分类号: B29C70/72
摘要: A vacuum mandrel for use in fabricating an implantable electrode comprises a hollow body member and a first groove provided radially on an outer surface of the hollow body member. The first groove is adapted to receive an implantable electrode and retain the electrode in place with a vacuum pressure during an elastomeric encapsulation of the electrode. The vacuum mandrel further comprises a vacuum port provided in the first groove.
摘要翻译: 用于制造可植入电极的真空心轴包括中空本体构件和径向设置在中空本体构件的外表面上的第一凹槽。 第一凹槽适于接收可植入电极,并且在电极的弹性体封装期间以真空压力将电极保持在适当的位置。 真空心轴还包括设置在第一凹槽中的真空口。
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公开(公告)号:US20080206207A1
公开(公告)日:2008-08-28
申请号:US12027984
申请日:2008-02-07
申请人: Paul Consigny , Gabriel Asongwe , Mary Beth Michaels , Gene Michal , Evgenia Mandrusov , Jeong Lee , Florian Ludwig , John Eric Henckel , Joseph J. Sciacca , Ken Bueche , Richard Todd Thornton , Fidel Albert Urrabazo , Daniel Wiegand
发明人: Paul Consigny , Gabriel Asongwe , Mary Beth Michaels , Gene Michal , Evgenia Mandrusov , Jeong Lee , Florian Ludwig , John Eric Henckel , Joseph J. Sciacca , Ken Bueche , Richard Todd Thornton , Fidel Albert Urrabazo , Daniel Wiegand
IPC分类号: A61K35/12 , A61K39/395 , A61P41/00
CPC分类号: A61K38/18 , A61K35/545 , A61K38/19 , A61K2300/00
摘要: Engraftment of therapeutic cells and agents to a target site in an organism is enhanced by mechanical, chemical and biological methods and systems.
摘要翻译: 通过机械,化学和生物学方法和系统,将治疗细胞和药剂移植到生物体的靶位点。
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