公开(公告)号：US5217905A

公开(公告)日：1993-06-08

申请号：US220895

申请日：1988-07-18

Applicant: Joseph Marchand ,  Jacques Toledano

Inventor： Joseph Marchand ,  Jacques Toledano

IPC: G01N33/543

CPC classification number: G01N33/54366 ,  Y10S435/805 ,  Y10S435/969 ,  Y10S435/97 ,  Y10S435/971 ,  Y10S436/805 ,  Y10S436/81

Abstract: A device for the rapid qualitative and quantitative determination of the presence of a reactive ligand in a fluid.This device comprises a first reaction zone in which there is an at least temporarily impermeable membrane designed to receive a sample of test fluid and to be associated with at least one labeled reagent; a second reaction zone which is bounded on the one hand by the said membrane and on the other by a second at least temporarily impermeable membrane comprising a solid phase containing a reference reagent; and a third reaction zone which contains means for developing the reaction.A method for the rapid qualitative and quantitative determination of the presence of a reactive ligand in a fluid.Applications to the detection of the presence, in a biological fluid, of antibodies or antigens in particular.

Abstract translation: 用于快速定性和定量测定流体中反应性配体的存在的装置。 该装置包括第一反应区，其中存在至少临时不可渗透的膜，其设计成接收测试流体的样品并与至少一种标记的试剂相关联; 第二反应区一方面由所述膜界定，另一方面由第二至少暂时不可渗透的膜包含含有参考试剂的固相; 和含有显影反应装置的第三反应区。 用于快速定性和定量测定流体中反应性配体的存在的方法。 用于检测在生物流体中尤其是抗体或抗原的存在。

公开(公告)号：US6160103A

公开(公告)日：2000-12-12

申请号：US147420

申请日：1998-12-21

Applicant: Joseph Marchand ,  Herve Bazin

Inventor： Joseph Marchand ,  Herve Bazin

IPC: G01N27/416 ,  C07H21/00 ,  C08G61/12 ,  C12N15/09 ,  C12Q1/68 ,  G01N27/327 ,  C07H21/02 ,  C07H19/00 ,  C07K1/00 ,  C07K14/00 ,  C07K16/00

CPC classification number: C07H21/00 ,  C08G61/124

Abstract: The invention concerns a macromolecule of formula (I): P-O-M in which M represents a molecule of interest, O represents an oligonucleotide chain; P represents a monomer of an electronic conductor polymer, and x and y are integers equal to 1 or more. The invention also concerns the copolymers obtained from the P-O-M macromolecules.

Abstract translation: PCT No.PCT / FR97 / 01134 Sec。 371 1998年12月21日第 102（e）1998年12月21日日期PCT 1997年6月25日PCT公布。 公开号WO97 / 49718 PCT。 日期：1997年12月31日本发明涉及式（I）的大分子：其中M表示目的分子的P-O-M，O表示寡核苷酸链; P表示电子导体聚合物的单体，x和y是等于1或更大的整数。 本发明还涉及从P-O-M大分子获得的共聚物。

公开(公告)号：US4115303A

公开(公告)日：1978-09-19

申请号：US689207

申请日：1976-05-24

Applicant: Joseph Marchand ,  Jean-Rene' Puig

Inventor： Joseph Marchand ,  Jean-Rene' Puig

IPC: B26F1/26 ,  C08J5/22 ,  C08J9/00 ,  C08J9/26 ,  C08L21/00 ,  C08F2/46

CPC classification number: B01D67/0032 ,  B26F1/26 ,  C08J5/2212 ,  C08J9/26 ,  C08J2301/02

Abstract: The method of fabrication of porous macromolecular materials which are primarily intended for use as ion-exchange membranes and selective semi-permeable membranes consists in subjecting a polymer to irradiation with heavy nuclear particles, in chemically fixing a monomer having at least one ethylene double bond in the zones which are modified by irradiation and localized around the locus of passage of each particle and in forming the pore structure by means of a chemical attacking agent which is specific to the starting polymer.

Abstract translation: 主要用作离子交换膜和选择性半透膜的多孔高分子材料的制造方法是将聚合物照射重质核颗粒，化学固定具有至少一个乙烯双键的单体 这些区域通过照射而改变，并且位于每个颗粒的通过轨迹周围，并且通过对起始聚合物特异的化学侵蚀剂形成孔结构。

公开(公告)号：US4151252A

公开(公告)日：1979-04-24

申请号：US832455

申请日：1977-09-12

Applicant: Joseph Marchand ,  Andre Roger

Inventor： Joseph Marchand ,  Andre Roger

IPC: G01N25/48 ,  G01N25/20

CPC classification number: G01N25/4866

Abstract: A heat-insulating enclosure contains temperature-regulating means and open-topped vessels each containing a sample of predetermined volume and transferred from a storage position to an analysis position in which a predetermined volume of reagent solution is contacted with the sample. Means are provided for detecting the respective temperatures of the sample and the reagent, for detecting the heat flux released and limiting thermal variations in the vicinity of each sample.

Abstract translation: 绝热外壳包含温度调节装置和敞口容器，每个容器包含预定体积的样品并从储存位置转移到预定体积的试剂溶液与样品接触的分析位置。 提供了用于检测样品和试剂的相应温度的装置，用于检测释放的热通量并限制每个样品附近的热变化。