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公开(公告)号：US07449307B2
公开(公告)日：2008-11-11
申请号：US10694639
申请日：2003-10-27
申请人： Michael Cima , Wendy Pryce Lewis , Javier Gonzalez-Zugasti , J. Richard Gyory , Anthony V. Lemmo , Julie Monagle
发明人： Michael Cima , Wendy Pryce Lewis , Javier Gonzalez-Zugasti , J. Richard Gyory , Anthony V. Lemmo , Julie Monagle
CPC分类号： B01L3/5085 , B01L3/5025 , B01L3/5088 , B01L2300/0609 , B01L2300/0819 , B01L2300/0829
摘要： The assay plate includes a substrate having an substrate surface and at least one raised pad extending from the substrate surface. The raised pad includes a substantially planar sample receiving surface configured for holding a sample thereon for in situ experimentation. The sample receiving surface preferably has at least one sharp edge at the junction between a sidewall coupling the sample receiving surface to the substrate surface. The sample receiving surface is preferably a circle, oval, square, rectangle, triangle, pentagon, hexagon, or octagon shape that is sized to hold a predetermined volume of the sample. A method of using the above described assay plate is also provided. Once a raised pad extending from a substrate is formed, a sample is deposited on the raised pad. Experiments are subsequently performed using the sample on the raised pad.
摘要翻译： 测定板包括具有基底表面的基底和从基底表面延伸的至少一个凸起垫。 凸起垫包括基本平坦的样品接收表面，其构造成用于将样品保持在其上用于原位实验。 样品接收表面优选在将样品接收表面耦合到衬底表面的侧壁之间的接合处具有至少一个尖锐边缘。 样品接收表面优选为圆形，椭圆形，正方形，矩形，三角形，五边形，六边形或八边形，其尺寸适于保持样品的预定体积。 还提供了使用上述测定板的方法。 一旦形成了从衬底延伸的凸起垫，则将样品沉积在凸起垫上。 随后使用凸起垫上的样品进行实验。
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公开(公告)号：US20070105185A1
公开(公告)日：2007-05-10
申请号：US10556996
申请日：2004-05-13
申请人： Michael Cima , Wendy Pryce Lewis , Javier Gonzalez-Zugasli , J. Gyory , Anthony Lemmo , Julie Monagle
发明人： Michael Cima , Wendy Pryce Lewis , Javier Gonzalez-Zugasli , J. Gyory , Anthony Lemmo , Julie Monagle
CPC分类号： B01L3/5085 , B01L3/5025 , B01L3/5088 , B01L2300/0609 , B01L2300/0819 , B01L2300/0829
摘要： The assay plate includes a substrate having an substrate surface and at least one raised pad extending from the substrate surface. The raised pad includes a substantially planar sample receiving surface configured for holding a sample thereon for in situ experimentation. The sample receiving surface preferably has at least one sharp edge at the junction between a sidewall coupling the sample receiving surface to the substrate surface. The sample receiving surface is preferably a circle, oval, square, rectangle, triangle, pentagon, hexagon, or octagon shape that is sized to hold a predetermined volume of the sample. A method of using the above described assay plate is also provided. Once a raised pad extending from a substrate is formed, a sample is deposited on the raised pad. Experiments are subsequently performed using the sample on the raised pad.
摘要翻译： 测定板包括具有基底表面的基底和从基底表面延伸的至少一个凸起垫。 凸起垫包括基本平坦的样品接收表面，其构造成用于将样品保持在其上用于原位实验。 样品接收表面优选在将样品接收表面耦合到衬底表面的侧壁之间的接合处具有至少一个尖锐边缘。 样品接收表面优选为圆形，椭圆形，正方形，矩形，三角形，五边形，六边形或八边形，其尺寸适于保持样品的预定体积。 还提供了使用上述测定板的方法。 一旦形成了从衬底延伸的凸起垫，则将样品沉积在凸起垫上。 随后使用凸起垫上的样品进行实验。
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公开(公告)号：US20050208477A1
公开(公告)日：2005-09-22
申请号：US11137592
申请日：2005-05-25
申请人： Michael Cima , Wendy Lewis , Javier Gonzalez-Zugasti , J. Gyory , Anthony Lemmo , Julie Monagle
发明人： Michael Cima , Wendy Lewis , Javier Gonzalez-Zugasti , J. Gyory , Anthony Lemmo , Julie Monagle
CPC分类号： B01L3/5088 , B01L2300/0829
摘要： The assay plate includes a substrate having an substrate surface and at least one raised pad extending from the substrate surface. The raised pad includes a substantially planar sample receiving surface configured for holding a sample thereon for in-situ experimentation. The sample receiving surface preferably has at least one sharp edge at the junction between a sidewall coupling the sample receiving surface to the substrate surface. The sample receiving surface is preferably a circle, oval, square, rectangle, triangle, pentagon, hexagon, or octagon shape that is sized to hold a predetermined volume of the sample. A method of using the above described assay plate is also provided. Once a raised pad extending from a substrate is formed, a sample is deposited on the raised pad. Experiments are subsequently performed using the sample on the raised pad.
摘要翻译： 测定板包括具有基底表面的基底和从基底表面延伸的至少一个凸起垫。 凸起垫包括被配置用于将样品保持在其上以用于现场实验的基本平坦的样品接收表面。 样品接收表面优选在将样品接收表面耦合到衬底表面的侧壁之间的接合处具有至少一个尖锐边缘。 样品接收表面优选为圆形，椭圆形，正方形，矩形，三角形，五边形，六边形或八边形，其尺寸适于保持样品的预定体积。 还提供了使用上述测定板的方法。 一旦形成了从衬底延伸的凸起垫，则将样品沉积在凸起垫上。 随后使用凸起垫上的样品进行实验。
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公开(公告)号：US07763455B2
公开(公告)日：2010-07-27
申请号：US10556996
申请日：2004-05-13
申请人： Michael Cima , Wendy Pryce-Lewis , Javier Gonzalez-Zugasti , J. Richard Gyory , Anthony Lemmo , Julie Monagle
发明人： Michael Cima , Wendy Pryce-Lewis , Javier Gonzalez-Zugasti , J. Richard Gyory , Anthony Lemmo , Julie Monagle
CPC分类号： B01L3/5085 , B01L3/5025 , B01L3/5088 , B01L2300/0609 , B01L2300/0819 , B01L2300/0829
摘要： The assay plate includes a substrate having an substrate surface and at least one raised pad extending from the substrate surface. The raised pad includes a substantially planar sample receiving surface configured for holding a sample thereon for in situ experimentation. The sample receiving surface preferably has at least one sharp edge at the junction between a sidewall coupling the sample receiving surface to the substrate surface. The sample receiving surface is preferably a circle, oval, square, rectangle, triangle, pentagon, hexagon, or octagon shape that is sized to hold a predetermined volume of the sample. A method of using the above described assay plate is also provided. Once a raised pad extending from a substrate is formed, a sample is deposited on the raised pad. Experiments are subsequently performed using the sample on the raised pad.
摘要翻译： 测定板包括具有基底表面的基底和从基底表面延伸的至少一个凸起垫。 凸起垫包括基本平坦的样品接收表面，其构造成用于将样品保持在其上用于原位实验。 样品接收表面优选在将样品接收表面耦合到衬底表面的侧壁之间的接合处具有至少一个尖锐边缘。 样品接收表面优选为圆形，椭圆形，正方形，矩形，三角形，五边形，六边形或八边形，其尺寸适于保持样品的预定体积。 还提供了使用上述测定板的方法。 一旦形成了从衬底延伸的凸起垫，则将样品沉积在凸起垫上。 随后使用凸起垫上的样品进行实验。
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公开(公告)号：US06908760B2
公开(公告)日：2005-06-21
申请号：US10439943
申请日：2003-05-16
申请人： Michael Cima , Wendy Pryce Lewis , Javier Gonzalez-Zugasti , J Richard Gyory , Anthony V. Lemmo , Julie Monagle
发明人： Michael Cima , Wendy Pryce Lewis , Javier Gonzalez-Zugasti , J Richard Gyory , Anthony V. Lemmo , Julie Monagle
CPC分类号： B01L3/5088 , B01L2300/0829
摘要： The assay plate includes a substrate having an substrate surface and at least one raised pad extending from the substrate surface. The raised pad includes a substantially planar sample receiving surface configured for holding a sample thereon for in-situ experimentation. The sample receiving surface preferably has at least one sharp edge at the junction between a sidewall coupling the sample receiving surface to the substrate surface. The sample receiving surface is preferably a circle, oval, square, rectangle, triangle, pentagon, hexagon, or octagon shape that is sized to hold a predetermined volume of the sample. A method of using the above described assay plate is also provided. Once a raised pad extending from a substrate is formed, a sample is deposited on the raised pad. Experiments are subsequently performed using the sample on the raised pad.
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