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公开(公告)号:US20080300206A1
公开(公告)日:2008-12-04
申请号:US12030849
申请日:2008-02-13
申请人: John P. Anderson , Kelly Banducci , Guriqbal S. Basi , David Chereau , Tamie J. Chilcote , Normand L. Frigon, JR. , Jason Goldstein , Irene Griswold-Prenner
发明人: John P. Anderson , Kelly Banducci , Guriqbal S. Basi , David Chereau , Tamie J. Chilcote , Normand L. Frigon, JR. , Jason Goldstein , Irene Griswold-Prenner
IPC分类号: A61K31/70 , C12N5/06 , A61K31/44 , A61K31/415 , A61K31/47 , A61K31/40 , C12Q1/48 , A01K67/027 , A61P25/00
CPC分类号: C12Q1/6883 , C12N15/1137 , C12N15/86 , C12N2310/11 , C12N2310/14 , C12N2740/15043 , C12Q1/485 , C12Q2600/136 , C12Q2600/158 , C12Y207/11016 , C12Y207/11021 , G01N2500/04 , G01N2800/28
摘要: The invention provides agents and methods for treatment of diseases associated with Lewy body diseases (LBDs) in the brain of a patient. Preferred agents include inhibitors of PLK2 kinase.
摘要翻译: 本发明提供了用于治疗与患者脑中的路易体疾病(LBD)相关的疾病的药剂和方法。 优选的试剂包括PLK2激酶的抑制剂。
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公开(公告)号:US20100143946A1
公开(公告)日:2010-06-10
申请号:US12702201
申请日:2010-02-08
申请人: JOHN P. ANDERSON , KELLY BANDUCCI , GURIQBAL S. BASI , DAVID CHEREAU , TAMIE J. CHILCOTE , NORMAND L. FRIGON, JR. , JASON GOLDSTEIN , IRENE GRISWOLD-PRENNER
发明人: JOHN P. ANDERSON , KELLY BANDUCCI , GURIQBAL S. BASI , DAVID CHEREAU , TAMIE J. CHILCOTE , NORMAND L. FRIGON, JR. , JASON GOLDSTEIN , IRENE GRISWOLD-PRENNER
IPC分类号: G01N33/567
CPC分类号: C12Q1/6883 , C12N15/1137 , C12N15/86 , C12N2310/11 , C12N2310/14 , C12N2740/15043 , C12Q1/485 , C12Q2600/136 , C12Q2600/158 , C12Y207/11016 , C12Y207/11021 , G01N2500/04 , G01N2800/28
摘要: The invention provides agents and methods for treatment of diseases associated with Lewy body diseases (LBDs) in the brain of a patient. Preferred agents include inhibitors of PLK2 kinase.
摘要翻译: 本发明提供了用于治疗与患者脑中的路易体疾病(LBD)相关的疾病的药剂和方法。 优选的试剂包括PLK2激酶的抑制剂。
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公开(公告)号:US20110207796A1
公开(公告)日:2011-08-25
申请号:US12865857
申请日:2009-02-13
申请人: John P. Anderson , Kelly Banducci , Guriqbal S. Basi , David Chereau , Tamie J. Chilcote , Normand L. Frigon, JR. , Jason Goldstein , Irene Griswold-Prenner
发明人: John P. Anderson , Kelly Banducci , Guriqbal S. Basi , David Chereau , Tamie J. Chilcote , Normand L. Frigon, JR. , Jason Goldstein , Irene Griswold-Prenner
IPC分类号: C12Q1/48 , C12N5/071 , A61K31/7105 , A61P25/28
CPC分类号: C12Q1/485 , C12N15/1137 , C12N2310/14 , G01N2500/04 , G01N2800/2835
摘要: Agents and methods for treatment of diseases associated with Lewy body diseases (LBDs) in the brain of a patient are provided. Preferred agents include inhibitors of PLK2 kinase.
摘要翻译: 提供了用于治疗与患者脑中路易体疾病(LBD)相关的疾病的药剂和方法。 优选的试剂包括PLK2激酶的抑制剂。
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公开(公告)号:US07553639B2
公开(公告)日:2009-06-30
申请号:US11669093
申请日:2007-01-30
申请人: Tami J. Chilcote , Kelly Banducci , Normand L. Frigon, Jr. , Guriqbal S. Basi , John P. Anderson , Jason Goldstein , Irene Griswold-Prenner , David Chereau
发明人: Tami J. Chilcote , Kelly Banducci , Normand L. Frigon, Jr. , Guriqbal S. Basi , John P. Anderson , Jason Goldstein , Irene Griswold-Prenner , David Chereau
CPC分类号: C12Q1/6883 , C12N15/1137 , C12N15/86 , C12N2310/11 , C12N2310/14 , C12N2740/15043 , C12Q1/485 , C12Q2600/136 , C12Q2600/158 , C12Y207/11016 , C12Y207/11021 , G01N2500/04 , G01N2800/28
摘要: The invention provides agents and methods for treatment of diseases associated with Lewy body diseases (LBDs) in the brain of a patient. Preferred agents include inhibitors of PLK2 and GRK6 kinases.
摘要翻译: 本发明提供了用于治疗与患者脑中的路易体疾病(LBD)相关的疾病的药剂和方法。 优选的试剂包括PLK2和GRK6激酶的抑制剂。
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公开(公告)号:US08148089B2
公开(公告)日:2012-04-03
申请号:US12702201
申请日:2010-02-08
申请人: John P. Anderson , Kelly Banducci , Guriqbal S. Basi , David Chereau , Tamie J. Chilcote , Normand L. Frigon, Jr. , Jason Goldstein , Irene Griswold
发明人: John P. Anderson , Kelly Banducci , Guriqbal S. Basi , David Chereau , Tamie J. Chilcote , Normand L. Frigon, Jr. , Jason Goldstein , Irene Griswold
IPC分类号: G01N33/53
CPC分类号: C12Q1/6883 , C12N15/1137 , C12N15/86 , C12N2310/11 , C12N2310/14 , C12N2740/15043 , C12Q1/485 , C12Q2600/136 , C12Q2600/158 , C12Y207/11016 , C12Y207/11021 , G01N2500/04 , G01N2800/28
摘要: The invention provides agents and methods for treatment of diseases associated with Lewy body diseases (LBDs) in the brain of a patient. Preferred agents include inhibitors of PLK2 kinase.
摘要翻译: 本发明提供了用于治疗与患者脑中的路易体疾病(LBD)相关的疾病的药剂和方法。 优选的试剂包括PLK2激酶的抑制剂。
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公开(公告)号:US20080160011A1
公开(公告)日:2008-07-03
申请号:US11669093
申请日:2007-01-30
申请人: Tami J. Chilcote , Kelly Banducci , Normand L. Frigon , Guriqbal S. Basi , John P. Anderson , Jason Goldstein , Irene Griswold-Prenner , David Chereau
发明人: Tami J. Chilcote , Kelly Banducci , Normand L. Frigon , Guriqbal S. Basi , John P. Anderson , Jason Goldstein , Irene Griswold-Prenner , David Chereau
CPC分类号: C12Q1/6883 , C12N15/1137 , C12N15/86 , C12N2310/11 , C12N2310/14 , C12N2740/15043 , C12Q1/485 , C12Q2600/136 , C12Q2600/158 , C12Y207/11016 , C12Y207/11021 , G01N2500/04 , G01N2800/28
摘要: The invention provides agents and methods for treatment of diseases associated with Lewy body diseases (LBDs) in the brain of a patient. Preferred agents include inhibitors of PLK2 and GRK6 kinases.
摘要翻译: 本发明提供了用于治疗与患者脑中的路易体疾病(LBD)相关的疾病的药剂和方法。 优选的试剂包括PLK2和GRK6激酶的抑制剂。
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