Lactobacillus plantarum KBL396 strain and use thereof

    公开(公告)号:US11602552B2

    公开(公告)日:2023-03-14

    申请号:US16962976

    申请日:2019-02-07

    申请人: KoBioLabs, Inc.

    摘要: The present invention relates to a composition comprising at least one selected from the group consisting of a novel lactic acid bacterium, Lactobacillus plantarum KBL396 (KCTC13278BP), culture of the strain, lysate of the strain and extract of the strain, and its use for food and medicine. The strain and composition according to the present invention has an excellent effect on improvement of neurological diseases, particularly improvement of mental disorders and neurodegenerative diseases, and has no risk of side effects in a human body, and thus it can be usefully utilized as a use for improvement of neurological diseases.

    AKKERMANSIA MUCINIPHILA STRAIN AND USE THEREOF

    公开(公告)号:US20220002665A1

    公开(公告)日:2022-01-06

    申请号:US17279247

    申请日:2019-10-11

    申请人: KoBioLabs, Inc.

    摘要: The present invention relates to Akkermansia muciniphila SNUG-61027 strain (accession number KCTC 13530BP) and use thereof, specifically, a composition for suppressing appetite or preventing, ameliorating, alleviating or treating metabolic diseases, comprising the strain, or a culture solution thereof, etc. or a B2UM07 protein isolated therefrom as an active ingredient, and use thereof for suppressing appetite or preventing, ameliorating, alleviating or treating metabolic diseases, and a method of suppressing appetite or preventing, ameliorating, alleviating or treating metabolic diseases using the same are provided. Through this, among the anti-obesity effects, not only weight reduction and glucose homeostasis regulation, but also the effect on brown fat and the effect of secreting appetite regulating hormones are exhibited.

    Lactobacillus Gasseri KBL697 Strain and Use Thereof

    公开(公告)号:US20220175858A1

    公开(公告)日:2022-06-09

    申请号:US17673488

    申请日:2022-02-16

    申请人: KoBioLabs, Inc.

    摘要: A strain of Lactobacillus gasseri KBL697 and the use thereof are described. The strain of Lactobacillus gasseri KBL697 (Accession No. KCTC 13520BP) attenuates allergic reactions of cells, significantly improves symptoms of atopic dermatitis, and exhibits anti-inflammatory and anti-fungal effects and a therapeutic effect for intestinal diseases such as irritable bowel syndrome and colitis. Thus, the single strain alone can achieve all the purposes of alleviating allergic diseases and inflammatory diseases and improving intestinal health, thereby finding advantageous applications as a probiotic substance. In addition, the strain, based on the anti-fungal activity thereof, can be advantageously utilized in a skin external preparation against various skin diseases caused by fungi, and in a cosmetic composition and a functional patch for alleviating sensitive skin.

    Lactobacillus crispatus KBL693 strain and use thereof

    公开(公告)号:US11633439B2

    公开(公告)日:2023-04-25

    申请号:US17448620

    申请日:2021-09-23

    申请人: KoBioLabs, Inc.

    摘要: A strain of Lactobacillus crispatus KBL693 and the use thereof are disclosed. The strain of Lactobacillus crispatus KBL693 (Accession No. KCTC 13519BP) attenuates allergic reactions of cells, significantly improves symptoms of atopic dermatitis, and exhibits anti-inflammatory and anti-fungal effects. Thus, the single strain alone can achieve all the purposes of alleviating atopic dermatitis and other allergic diseases and improving inflammatory diseases and autoimmune diseases, thereby finding advantageous applications as a probiotic substance. In addition, the strain, based on the anti-fungal activity thereof, can be advantageously utilized in a skin external preparation against various skin diseases caused by fungi, and in a cosmetic composition and a functional patch for alleviating sensitive skin.