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公开(公告)号：US20110288141A1
公开(公告)日：2011-11-24
申请号：US12674614
申请日：2008-08-29
IPC分类号： A61K31/415 , A61P33/14
CPC分类号： A61K9/0014 , A01N47/02 , A61K31/00 , A61K31/415 , A61K45/06 , A61K47/10 , A01N25/02 , A01N2300/00 , A61K2300/00
摘要： The present invention provides formulations and methods useful in eradicating ectoparasites on a domestic animal, decreasing the number of ectoparasites on a domestic animal, and/or preventing ectoparasite infestation on a domestic animal, using a local topical formulation comprising fiproniland a veterinarily acceptable carrier.
摘要翻译： 本发明提供了使用包含氟虫腈和兽医学上可接受的载体的局部局部制剂，有用的消除家畜的外寄生物，减少家畜的外寄生虫数量和/或预防家畜的寄生虫寄生虫的制剂和方法。
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公开(公告)号：US10045940B2
公开(公告)日：2018-08-14
申请号：US13286747
申请日：2011-11-01
申请人： Keith A. Freehauf , Jay Brumfield , Roger Tully
发明人： Keith A. Freehauf , Jay Brumfield , Roger Tully
摘要： This invention relates to compositions (e.g., otic compositions) comprising an antibiotic (generally a quinolone or naphthyridinone), corticosteroid, and organic acid (generally a fatty acid). This invention also relates to treatment methods using such a composition, uses of such a composition to make medicaments, and therapeutic kits comprising such a composition.
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公开(公告)号：US20120046259A1
公开(公告)日：2012-02-23
申请号：US13286747
申请日：2011-11-01
申请人： Keith A. FREEHAUF , Jay Brumfield , Roger Tully
发明人： Keith A. FREEHAUF , Jay Brumfield , Roger Tully
CPC分类号： A61K9/10 , A61K9/0046 , A61K9/14 , A61K31/496 , A61K31/58 , A61K45/06 , A61K47/12 , A61K2300/00
摘要： This invention relates to compositions (e.g., otic compositions) comprising an antibiotic (generally a quinolone or naphthyridinone), corticosteroid, and organic acid (generally a fatty acid). This invention also relates to treatment methods using such a composition, uses of such a composition to make medicaments, and therapeutic kits comprising such a composition.
摘要翻译： 本发明涉及包含抗生素（通常为喹诺酮或萘啶酮），皮质类固醇和有机酸（通常为脂肪酸）的组合物（例如耳用组合物）。 本发明还涉及使用这种组合物的治疗方法，这种组合物的用途来制备药物，以及包含这种组合物的治疗试剂盒。
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公开(公告)号：US20080153906A1
公开(公告)日：2008-06-26
申请号：US11953978
申请日：2007-12-11
IPC分类号： A61K31/222
CPC分类号： A61K31/222 , A61K9/0019 , A61K47/14
摘要： The present invention discloses pharmaceutical compositions containing a suspension of a therapeutically effective amount of a water-soluble prodrug of a phenicol in a lipophilic vehicle system.
摘要翻译： 本发明公开了含有治疗有效量的在亲油性载体系统中的酚的水溶性前药的悬浮液的药物组合物。
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公开(公告)号：US06790867B2
公开(公告)日：2004-09-14
申请号：US10350884
申请日：2003-01-24
IPC分类号： A61K31165
CPC分类号： A61K9/0019 , A61K31/16 , A61K31/165 , A61K31/18 , A61K31/277 , A61K31/44 , A61K31/455 , A61K31/655 , A61K31/66 , A61K47/10 , A61K47/22 , Y10S514/846 , Y10S514/847 , Y10S514/947 , A61K2300/00
摘要： Novel formulations combining a non-steroidal anti-inflammatory drug (NSAID) such as flunixin, with a fluorinated chloramphenicol or thiamphenicol derivative antibiotic such as florfenicol are disclosed. Methods for using such formulations in the treatment and prevention of infectious diseases of bovines and swine, including bovine respiratory disease and swine respiratory disease, are also disclosed.
摘要翻译： 公开了将非甾体抗炎药（NSAID）如氟尼昔宁与氟化氯霉素或甲砜霉素衍生物抗生素如氟苯尼考组合的新型制剂。 还公开了使用这些制剂治疗和预防牛和猪感染性疾病（包括牛呼吸道疾病和猪呼吸道疾病）的方法。
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公开(公告)号：US08044102B2
公开(公告)日：2011-10-25
申请号：US11206358
申请日：2005-08-18
申请人： Raul E. Kohan , Kanwal J. Varma , Robert D. Simmons , Abu Huq , Keith A Freehauf
发明人： Raul E. Kohan , Kanwal J. Varma , Robert D. Simmons , Abu Huq , Keith A Freehauf
IPC分类号： A01N37/18 , A01N43/40 , A61K31/165 , A61K31/44
CPC分类号： A61K9/0019 , A61K31/16 , A61K31/165 , A61K31/18 , A61K31/277 , A61K31/44 , A61K31/455 , A61K31/655 , A61K31/66 , A61K47/10 , A61K47/22 , Y10S514/846 , Y10S514/847 , Y10S514/947 , A61K2300/00
摘要： Novel formulations combining a non-steroidal anti-inflammatory drug (NSAID) such as flunixin, with a fluorinated chloramphenicol or thiamphenicol derivative antibiotic such as florfenicol are disclosed. Methods for using such formulations in the treatment and prevention of infectious diseases of bovines and swine, including bovine respiratory disease and swine respiratory disease, are also disclosed.
摘要翻译： 公开了将非甾体抗炎药（NSAID）如氟尼克辛与氟化氯霉素或甲砜霉素衍生物抗生素如氟苯尼考组合的新型制剂。 还公开了使用这些制剂治疗和预防牛和猪感染性疾病（包括牛呼吸道疾病和猪呼吸道疾病）的方法。
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公开(公告)号：US08034845B2
公开(公告)日：2011-10-11
申请号：US10857695
申请日：2004-05-28
IPC分类号： A61K31/00
CPC分类号： A61K9/0019 , A61K31/10 , A61K31/16 , A61K31/165 , A61K31/195 , A61K31/21 , A61K31/4015 , A61K31/655 , A61K31/66 , A61K47/14 , A61K47/32 , Y10S514/947
摘要： Novel formulations containing a fluorinated chloramphenicol or thiamphenicol derivative antibiotic such as florfenicol, and methods for using such formulations in the treatment and prevention of infectious diseases of bovines and swine, including bovine respiratory disease.
摘要翻译： 含有氟化氯霉素或甲砜霉素衍生物抗生素如氟苯尼考的新型制剂，以及使用这些制剂治疗和预防牛和猪的感染性疾病（包括牛呼吸道疾病）的方法。
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8.发明申请PHARMACEUTICAL COMPOSITIONS AND METHOD FOR TREATING INFLAMMATION IN CATTLE AND OTHER ANIMALS 有权药物组合物及其在动物及其他动物中治疗炎症的方法公开(公告)号：US20080153885A1
公开(公告)日：2008-06-26
申请号：US11959185
申请日：2007-12-18
CPC分类号： A61K31/44 , A61K9/0017 , A61K47/06 , A61K47/10 , A61K47/14 , A61K47/16 , A61K47/20 , Y10S514/947
摘要： Novel transdermal preparations combining a non-steroidal anti-inflammatory drug (NSAID) such as flunixin, are disclosed. Methods for using and administering such preparation in the treatment of inflammatory conditions in bovines, including bovine respiratory disease, are also disclosed.
摘要翻译： 公开了组合非甾体抗炎药（NSAID）如氟尼辛的新型透皮制剂。 还公开了在牛，包括牛呼吸系统疾病的治疗炎症状态下使用和施用该制剂的方法。
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9.发明申请EFFERVESCENT FORMULATIONS OF FLORFENICOL FOR ADDITION IN DRINKING WATER SYSTEMS 审中-公开维生素在饮用水系统中的添加剂的有效配方公开(公告)号：US20080145317A1
公开(公告)日：2008-06-19
申请号：US11957668
申请日：2007-12-17
申请人： SERENA TONGIANI , Keith A. Freehauf
发明人： SERENA TONGIANI , Keith A. Freehauf
CPC分类号： A61K9/0007 , A61K9/0095
摘要： The invention relates to an effervescent formulation containing florfenicol or an antibiotic of related structure. When introduced into water, the effervescent formulation is dissolved with minimal or no agitation and provides a solution or a homogeneous dispersion of florfenicol. The formulations are typically in the form of free flowing powders, granules or tablets. The effervescent formulations are useful for the treatment of bacterial infections and allow for the rapid dispersion and dissolution of florfenicol in the drinking water systems of an animal in need of such treatment.
摘要翻译： 本发明涉及含有氟苯尼考或相关结构的抗生素的泡腾制剂。 当引入水中时，泡腾制剂在最少或不搅拌下溶解，并提供氟苯尼考溶液或均匀分散体。 制剂通常为自由流动的粉末，颗粒或片剂的形式。 泡腾制剂可用于治疗细菌感染并允许氟苯尼考在需要这种治疗的动物的饮用水系统中快速分散和溶解。
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公开(公告)号：US09084719B2
公开(公告)日：2015-07-21
申请号：US13224739
申请日：2011-09-02
IPC分类号： A61K31/10 , A61K31/165 , A61K31/21 , A61K31/4015 , A61K9/00 , A61K31/16 , A61K31/195 , A61K31/655 , A61K31/66 , A61K47/14 , A61K47/32
CPC分类号： A61K9/0019 , A61K31/10 , A61K31/16 , A61K31/165 , A61K31/195 , A61K31/21 , A61K31/4015 , A61K31/655 , A61K31/66 , A61K47/14 , A61K47/32 , Y10S514/947
摘要： Novel formulations containing a fluorinated chloramphenicol or thiamphenicol derivative antibiotic such as florfenicol, and methods for using such formulations in the treatment and prevention of infectious diseases of bovines and swine, including bovine respiratory disease.
摘要翻译： 含有氟化氯霉素或甲砜霉素衍生物抗生素如氟苯尼考的新型制剂，以及使用这些制剂治疗和预防牛和猪的感染性疾病（包括牛呼吸道疾病）的方法。
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