公开(公告)号：US07518025B2

公开(公告)日：2009-04-14

申请号：US10532709

申请日：2003-10-29

申请人： Takeshi Kawai ,  Kenji Inamasa

发明人： Takeshi Kawai ,  Kenji Inamasa

IPC分类号： C07C15/08 ,  C07C15/067

CPC分类号： C07C5/2718 ,  C07C2/70

摘要： A process is provided for producing an alkyl aromatic compound having substituents at the 3- and 5-positions by alkylating an aromatic compound having two substituents in the meta positions with an olefin having 2 to 4 carbon atoms in the presence of a Broensted acid, followed by addition of a Lewis acid and isomerization in the copresence of the Broensted acid and the Lewis acid. According to the present invention, 3,5-dimethylethylbenzene, 3,5-dimethylcumene, etc. may be produced in a stable manner with high yield and high selectivity under mild and simple reaction conditions. The alkyl aromatic compounds having substituents at the 3- and 5-positions are useful as intermediates for functional chemicals for use in pharmaceutical, agricultural and electronic materials. With the method of the present invention, the catalyst used can be recovered and recycled. Thus, desired alkyl aromatic compounds may be obtained economically in an industrially advantageous manner while reducing the load on the environment.

摘要翻译： 提供了一种通过在布朗斯台德酸的存在下，通过在间位具有2〜4个碳原子的烯烃的芳族化合物烷基化而在3-和5-位具有取代基的烷基芳族化合物的制备方法，随后 通过在布朗斯台德酸和路易斯酸的共存中加入路易斯酸和异构化。 根据本发明，可以在温和和简单的反应条件下以高产率和高选择性以稳定的方式制备3,5-二甲基乙基苯，3,5-二甲基枯烯等。 在3-和5-位具有取代基的烷基芳族化合物可用作用于制药，农业和电子材料的功能性化学品的中间体。 利用本发明的方法，可以回收和再循环所用的催化剂。 因此，可以以工业上有利的方式经济地获得所需的烷基芳族化合物，同时减少对环境的负荷。

公开(公告)号：US5367098A

公开(公告)日：1994-11-22

申请号：US47812

申请日：1993-04-15

申请人： Norio Fushimi ,  Ko Kedo ,  Kenji Inamasa ,  Makoto Takagawa

发明人： Norio Fushimi ,  Ko Kedo ,  Kenji Inamasa ,  Makoto Takagawa

IPC分类号： B01J23/04 ,  B01J27/232 ,  C07B61/00 ,  C07C2/72 ,  C07C15/44

CPC分类号： B01J27/232 ,  B01J23/04 ,  C07C2/72 ,  C07C2521/04 ,  C07C2523/04

摘要： A process for producing a monoalkenyl aromatic hydrocarbon compound which comprises alkenylating a side chain of an aromatic hydrocarbon compound having at least one hydrogen atom bonded at an .alpha.-position of the side chain (such as xylene) with a conjugated diene having 4 or 5 carbon atoms (such as butadiene) in the presence of a catalyst comprising a mixture obtained by heat treating metallic sodium together with a mixture of an aluminum oxide and a potassium compound in an inert gas atmosphere. The process produces a commercially useful monoalkenyl aromatic hydrocarbon compounds in a high yields and at a low cost with enhanced safety.

摘要翻译： 一种单链烯基芳族烃化合物的制造方法，其特征在于，将具有至少一个在侧链的α位键合的氢原子（例如二甲苯）的芳香族烃化合物的侧链与具有4或5个碳原子的共轭二烯 在包含通过在惰性气体气氛中将金属钠与氧化铝和钾化合物的混合物一起热处理获得的混合物的催化剂存在下的原子（例如丁二烯）。 该方法以高产率和低成本产生商业上可用的单链烯基芳族烃化合物，具有增强的安全性。

公开(公告)号：US5344806A

公开(公告)日：1994-09-06

申请号：US011216

申请日：1993-01-29

申请人： Norio Fushimi ,  Kenji Inamasa ,  Makoto Takagawa

发明人： Norio Fushimi ,  Kenji Inamasa ,  Makoto Takagawa

IPC分类号： B01J23/04 ,  C07B61/00 ,  C07C2/72 ,  C07C15/44

CPC分类号： B01J23/04 ,  C07C2/72 ,  C07C2521/10 ,  C07C2523/02 ,  C07C2523/04

摘要： There is disclosed a process for producing a monoalkenyl aromatic hydrocarbon compound which comprises alkenylating a side chain of an aromatic hydrocarbon compound having at least one hydrogen atom bonded at .alpha.-position of the side chain (such as xylene) with a conjugated diene having 4 or 5 carbon atoms (such as butadiene) in the presence of a catalyst comprising the mixture obtained by heat treating metallic sodium together with an alkaline earth metal oxide containing a potassium compound in the atmosphere of an inert gas. According to the aforesaid process, a monoalkenyl aromatic hydrocarbon compound such as industrially useful monoalkenylbenzene can be produced in high yield at a low cost with enhanced safety from a specific aromatic hydrocarbon compound and a specific conjugated diene compound.

摘要翻译： 公开了一种单烯基芳族烃化合物的制造方法，该方法包括使具有至少一个在侧链（例如二甲苯）的α位键合的氢原子的芳族烃化合物的侧链与具有4或 在包含通过在惰性气体气氛中将金属钠与含有钾化合物的碱土金属氧化物一起热处理的混合物的催化剂存在下，将5个碳原子（例如丁二烯）。 根据上述方法，可以以低成本高产率生产工业上可用的单链烯基单链烯基芳烃化合物，从特定的芳族烃化合物和特定的共轭二烯化合物的安全性提高。

公开(公告)号：US07102025B2

公开(公告)日：2006-09-05

申请号：US10951592

申请日：2004-09-29

申请人： Kentaro Kataoka ,  Yoshikazu Shima ,  Kenji Inamasa

发明人： Kentaro Kataoka ,  Yoshikazu Shima ,  Kenji Inamasa

IPC分类号： C07C253/28 ,  C07B43/08

CPC分类号： C07C253/28 ,  C07C255/50

摘要： In the production method of the invention, a cyclic aldehyde having an alkyl group and/or a cycloalkyl group directly bonded to a skeletal ring and a formyl group directly bonded to the skeletal ring is brought into contact with ammonia and oxygen in vapor phase in the presence of a catalyst. As a result thereof, the formyl group is selectively ammoxidized into a cyano group to convert the cyclic aldehyde into a corresponding cyclic nitrile. The method enables a long-term, high-yield production of the cyclic nitrile using a reduced amount of ammonia.

摘要翻译： 在本发明的制造方法中，将与骨架环直接键合的具有烷基和/或环烷基的环醛和与骨架环直接结合的甲酰基与气相中的氨和氧接触， 存在催化剂。 作为其结果，甲酰基被选择性氨氧化成氰基以将环醛转化为相应的环腈。 该方法能够使用氨的量减少量的长期高产率的环腈。

公开(公告)号：US5396007A

公开(公告)日：1995-03-07

申请号：US86506

申请日：1993-07-01

申请人： Yoichi Kyuko ,  Shinji Ozawa ,  Makoto Takagawa ,  Kenji Inamasa

发明人： Yoichi Kyuko ,  Shinji Ozawa ,  Makoto Takagawa ,  Kenji Inamasa

IPC分类号： B01J23/42 ,  B01J23/44 ,  C07B61/00 ,  C07C5/367 ,  C07C15/24 ,  C07C5/00

CPC分类号： C07C5/367

摘要： A process for producing dimethylnaphthalene by the dehydrogenation of dimethyl-tetrahydronaphthalene which comprises carrying out the dehydrogenation reaction in a gaseous state at a temperature of 200.degree. to 350.degree. C. in the presence of a diluting medium and by the use of a platinum and/or palladium catalyst supported on an activated carbon carrier. The process is capable of producing industrially useful dimethylnaphthalene with a high yield and a high selectivity and minimized side reactions, over a long stabilized period.

摘要翻译： 通过二氢四氢萘的脱氢生产二甲基萘的方法，包括在稀释介质存在下，在200-350℃的温度下以气态进行脱氢反应，并通过使用铂和/ 或负载在活性炭载体上的钯催化剂。 该方法能够在长期稳定的时间内以高产率和高选择性和最小化的副反应生产工业上有用的二甲基萘。

公开(公告)号：US20060122439A1

公开(公告)日：2006-06-08

申请号：US10532709

申请日：2003-10-29

申请人： Takeshi Kawai ,  Kenji Inamasa

发明人： Takeshi Kawai ,  Kenji Inamasa

IPC分类号： C07C17/26 ,  C07C205/00

CPC分类号： C07C5/2718 ,  C07C2/70

摘要： A process is provided for producing an alkyl aromatic compound having substituents at the 3- and 5-positions by alkylating an aromatic compound having two substituents in the meta positions with an olefin having 2 to 4 carbon atoms in the presence of a Broensted acid, followed by addition of a Lewis acid and isomerization in the copresence of the Broensted acid and the Lewis acid. According to the present invention, 3,5-dimethylethylbenzene, 3,5-dimethylcumene, etc. may be produced in a stable manner with high yield and high selectivity under mild and simple reaction conditions. The alkyl aromatic compounds having substituents at the 3- and 5-positions are useful as intermediates for functional chemicals for use in pharmaceutical, agricultural and electronic materials. With the method of the present invention, the catalyst used can be recovered and recycled. Thus, desired alkyl aromatic compounds may be obtained economically in an industrially advantageous manner while reducing the load on the environment.

摘要翻译： 提供了一种通过在布朗斯台德酸存在下通过烷基化具有2至4个碳原子的烯烃在间位中具有两个取代基的芳族化合物在3-和5-位上具有取代基的方法， 通过在布朗斯台德酸和路易斯酸的共存中加入路易斯酸和异构化。 根据本发明，可以在温和和简单的反应条件下以高产率和高选择性以稳定的方式制备3,5-二甲基乙基苯，3,5-二甲基枯烯等。 在3-和5-位具有取代基的烷基芳族化合物可用作用于制药，农业和电子材料的功能性化学品的中间体。 利用本发明的方法，可以回收和再循环所用的催化剂。 因此，可以以工业上有利的方式经济地获得所需的烷基芳族化合物，同时减少对环境的负荷。

公开(公告)号：US5276230A

公开(公告)日：1994-01-04

申请号：US944363

申请日：1992-09-14

申请人： Kenji Inamasa ,  Norio Fushimi ,  Makoto Takagawa

发明人： Kenji Inamasa ,  Norio Fushimi ,  Makoto Takagawa

IPC分类号： B01J23/58 ,  C07B61/00 ,  C07C5/393 ,  C07C5/41 ,  C07C15/24 ,  C07C5/00

CPC分类号： B01J23/58 ,  C07C5/417

摘要： There is disclosed a process for efficiently producing 2,6-dimethylnaphthalene used for the production of polyethylene naphthalate which comprises subjecting 2-methyl-1-(p-tolyl)butene and/or 2-methyl-1-(p-tolyl)butane as a starting raw material to cyclization dehydrogenation reaction by the use of a catalyst comprising a platinum component and at least one component selected from the group consisting of alkali metals and alkaline earth metals each being supported on aluminum oxide. The above process enables the production of the objective compound in a high yield at a low cost by using the catalyst having high safety and stability from the widely available starting material, thereby enhancing the industrial significance of the process.

摘要翻译： 公开了一种有效生产用于生产聚萘二甲酸乙二醇酯的2,6-二甲基萘的方法，该方法包括使2-甲基-1-（对甲苯基）丁烯和/或2-甲基-1-（对甲苯基）丁烷 作为起始原料，通过使用包含铂成分和至少一种选自碱金属和碱土金属的组分的催化剂进行环化脱氢反应，所述碱金属和碱土金属各自负载在氧化铝上。 上述方法能够通过使用来自广泛可得的原料的高安全性和稳定性的催化剂以低成本高产率生产目标化合物，从而提高了该方法的工业意义。

公开(公告)号：US5068480A

公开(公告)日：1991-11-26

申请号：US621260

申请日：1990-12-03

申请人： Makoto Takagawa ,  Ken Yamagishi ,  Jyun Yoshihara ,  Kenji Inamasa ,  Kumiko Watabe

发明人： Makoto Takagawa ,  Ken Yamagishi ,  Jyun Yoshihara ,  Kenji Inamasa ,  Kumiko Watabe

IPC分类号： C07C5/41 ,  C07C5/00

CPC分类号： C07C5/412

摘要： A process for producing 2,6-dimethylnaphthalene, which comprises subjecting 2-methyl-1-(p-tolyl)-butene, 2-methyl-1-(p-tolyl)-butane or a mixture of these to cyclization and dehydrogenation in the presence of a catalyst comprising lead oxide and/or indium oxide and aluminum oxide.

公开(公告)号：US20050124823A1

公开(公告)日：2005-06-09

申请号：US10951592

申请日：2004-09-29

申请人： Kentaro Kataoka ,  Yoshikazu Shima ,  Kenji Inamasa

发明人： Kentaro Kataoka ,  Yoshikazu Shima ,  Kenji Inamasa

IPC分类号： C07B43/08 ,  C07C253/28 ,  C07C255/50 ,  C07C253/00

CPC分类号： C07C253/28 ,  C07C255/50

摘要： In the production method of the invention, a cyclic aldehyde having an alkyl group and/or a cycloalkyl group directly bonded to a skeletal ring and a formyl group directly bonded to the skeletal ring is brought into contact with ammonia and oxygen in vapor phase in the presence of a catalyst. As a result thereof, the formyl group is selectively ammoxidized into a cyano group to convert the cyclic aldehyde into a corresponding cyclic nitrile. The method enables a long-term, high-yield production of the cyclic nitrile using a reduced amount of ammonia.

摘要翻译： 在本发明的制造方法中，将与骨架环直接键合的具有烷基和/或环烷基的环醛和与骨架环直接结合的甲酰基与气相中的氨和氧接触， 存在催化剂。 作为其结果，甲酰基被选择性氨氧化成氰基以将环醛转化为相应的环腈。 该方法能够使用氨的量减少量的长期高产率的环腈。

公开(公告)号：US5444172A

公开(公告)日：1995-08-22

申请号：US170493

申请日：1993-12-20

申请人： Makoto Takagawa ,  Kenji Inamasa ,  Norio Fushimi ,  Akio Hashimoto ,  Takayo Sasaki

发明人： Makoto Takagawa ,  Kenji Inamasa ,  Norio Fushimi ,  Akio Hashimoto ,  Takayo Sasaki

IPC分类号： B01J23/04 ,  B01J27/232 ,  C07B61/00 ,  C07C2/72 ,  C07C15/44

CPC分类号： B01J27/232 ,  B01J23/04 ,  C07C2/72 ,  C07C2521/04 ,  C07C2523/04 ,  C07C2527/232 ,  Y02P20/52

摘要： There is disclosed a process for producing a monoalkenylbenzene which comprises alkenylating a side chain of an aromatic hydrocarbon compound having at least one hydrogen atom bonded at .alpha.-position of the side chain (such as xylene) with a conjugated diene having 4 or 5 carbon atoms (such as butadiene) in the presence of a catalyst produced by calcining the mixture of a basic potassium compound and alumina and then heat treating the calcined product together with metallic sodium in an atmosphere of an inert gas. According to the aforesaid process, an industrially useful monoalkenylbenzene can be produced in high yield at a low cost with enhanced safety.

摘要翻译： 公开了一种单链烯基苯的制备方法，该方法包括将具有至少一个在侧链（例如二甲苯）的α位键合的氢原子的芳族烃化合物的侧链与具有4或5个碳原子的共轭二烯链烯基化 （例如丁二烯）在通过煅烧碱性钾化合物和氧化铝的混合物产生的催化剂存在下，然后在惰性气体气氛中将煅烧产物与金属钠一起热处理。 根据上述方法，可以低成本，高安全性地以高产率生产工业上有用的单烯基苯。