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公开(公告)号：US20130144055A1
公开(公告)日：2013-06-06
申请号：US13755466
申请日：2013-01-31
申请人： George Adjabeng , Jerry Leroy Adams , Scott Howard Dickerson , Keith Hornberger , Neil W. Johnson , Kevin Kuntz , Kimberly Petrov , Jeffrey M. Ralph , Tara Renae Rheault , Gregory Schaaf , John Stellwagen , Xinrong Tian , David E. Uehling , Alex G. Waterson , Brian Wilson
发明人： George Adjabeng , Jerry Leroy Adams , Scott Howard Dickerson , Keith Hornberger , Neil W. Johnson , Kevin Kuntz , Kimberly Petrov , Jeffrey M. Ralph , Tara Renae Rheault , Gregory Schaaf , John Stellwagen , Xinrong Tian , David E. Uehling , Alex G. Waterson , Brian Wilson
IPC分类号： C07D417/14 , C07D417/04 , C07D413/04 , C07D413/14 , C07D403/14
CPC分类号： C07D417/14 , A61K31/427 , C07D413/04 , C07D413/14 , C07D417/04
摘要： The present invention provides thiazole sulfonamide and oxazole sulfonamide compounds, compositions containing the same, as well as processes for the preparation and methods for their use as pharmaceutical agents.
摘要翻译： 本发明提供噻唑磺酰胺和恶唑磺酰胺化合物，含有它们的组合物，以及其制备方法和用作药剂的方法。
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公开(公告)号：US20110230476A1
公开(公告)日：2011-09-22
申请号：US12878965
申请日：2010-09-09
申请人： DEQIANG NIU , RUSSELL C. PETTER , JUSWINDER SINGH , ARTHUR F. KLUGE , HORMOZ MAZDIYASNI , ZHENDONG ZHU , LIXIN QIAO , KEVIN KUNTZ
发明人： DEQIANG NIU , RUSSELL C. PETTER , JUSWINDER SINGH , ARTHUR F. KLUGE , HORMOZ MAZDIYASNI , ZHENDONG ZHU , LIXIN QIAO , KEVIN KUNTZ
IPC分类号： A61K31/538 , C07D413/14 , A61K31/5377 , C07D487/04 , A61K31/519 , C07D401/14 , A61K31/4709 , C07D417/14 , A61K31/4725 , A61K31/496 , C07D495/04 , A61P35/00 , C12N9/99 , C12N9/96
CPC分类号： C12N9/1205
摘要： The present invention provides compounds, compositions thereof, and methods of using the same.
摘要翻译： 本发明提供化合物，其组合物及其使用方法。
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公开(公告)号：US20110172215A1
公开(公告)日：2011-07-14
申请号：US12991004
申请日：2009-05-04
申请人： George Adjabeng , Jeffrey Leroy Adams , Scott Howard Dickerson , Keith Hornberger , Neil W. Johnson , Kevin Kuntz , Kimberly Petrov , Jeffrey M. Ralph , Tara Renae Rheault , Gregory Schaaf , John Stellwagen , Xinrong Tian , David E. Uehling , Alex G. Waterson , Brian Wilson
发明人： George Adjabeng , Jeffrey Leroy Adams , Scott Howard Dickerson , Keith Hornberger , Neil W. Johnson , Kevin Kuntz , Kimberly Petrov , Jeffrey M. Ralph , Tara Renae Rheault , Gregory Schaaf , John Stellwagen , Xinrong Tian , David E. Uehling , Alex G. Waterson , Brian Wilson
IPC分类号： A61K31/541 , C07D417/14 , A61K31/5377 , A61K31/506 , C07D413/14 , C07D417/04 , A61P35/00
CPC分类号： C07D417/14 , A61K31/427 , C07D413/04 , C07D413/14 , C07D417/04
摘要： The present invention provides thiazole sulfonamide and oxazole sulfonamide compounds, compositions containing the same, as well as processes for the preparation and methods for their use as pharmaceutical agents.
摘要翻译： 本发明提供噻唑磺酰胺和恶唑磺酰胺化合物，含有它们的组合物，以及其制备方法和用作药剂的方法。
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公开(公告)号：US20060217382A1
公开(公告)日：2006-09-28
申请号：US10550434
申请日：2004-03-29
申请人： Mui Cheung , Nigel King , Kevin Kuntz , Robert Mook , Mark Pobanz , James Salovich , Brian Wilson
发明人： Mui Cheung , Nigel King , Kevin Kuntz , Robert Mook , Mark Pobanz , James Salovich , Brian Wilson
IPC分类号： A61K31/53 , C07D487/04
CPC分类号： C07D487/04
摘要： The present invention provides compounds of formula (I): wherein all variables are as defined herein, pharmaceutical compositions containing the same, processes for preparing the same and their use as pharmaceutical agents.
摘要翻译： 本发明提供式（I）化合物：其中所有变量如本文所定义，含有该化合物的药物组合物，其制备方法及其作为药剂的用途。
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公开(公告)号：US06693168B1
公开(公告)日：2004-02-17
申请号：US09396132
申请日：1999-09-14
IPC分类号： C07K700
CPC分类号： C07K5/0827
摘要： Methods for preparing chiral non-racemic cyanoamines are provided. The methods are useful, e.g., for preparing chiral amino acids.
摘要翻译： 提供了制备手性非外消旋氰胺的方法。 所述方法是有用的，例如用于制备手性氨基酸。
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公开(公告)号：US07615643B2
公开(公告)日：2009-11-10
申请号：US11754653
申请日：2007-05-29
申请人： Kevin Kuntz , Kyle Allen Emmitte , Tara Renae Rheault , Stephon Smith , Keith Hornberger , Hamilton Dickson , Mui Cheung
发明人： Kevin Kuntz , Kyle Allen Emmitte , Tara Renae Rheault , Stephon Smith , Keith Hornberger , Hamilton Dickson , Mui Cheung
IPC分类号： A61K31/445 , A61K31/4184 , C07D401/14 , C07D409/04
CPC分类号： C07D409/04 , C07D409/14 , C07D413/14
摘要： The present invention provides benzimidazole thiophene compounds pharmaceutical compositions containing the same, processes for preparing the same and their use as pharmaceutical agents.
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公开(公告)号：US08415345B2
公开(公告)日：2013-04-09
申请号：US12991004
申请日：2009-05-04
申请人： George Adjabeng , Jerry Leroy Adams , Scott Howard Dickerson , Keith Hornberger , Neil W. Johnson , Kevin Kuntz , Kimberly Petrov , Jeffrey M. Ralph , Tara Renae Rheault , Gregory Schaaf , John Stellwagen , Xinrong Tian , David E. Uehling , Alex G. Waterson , Brian Wilson
发明人： George Adjabeng , Jerry Leroy Adams , Scott Howard Dickerson , Keith Hornberger , Neil W. Johnson , Kevin Kuntz , Kimberly Petrov , Jeffrey M. Ralph , Tara Renae Rheault , Gregory Schaaf , John Stellwagen , Xinrong Tian , David E. Uehling , Alex G. Waterson , Brian Wilson
IPC分类号： C07D403/14 , A61K31/505
CPC分类号： C07D417/14 , A61K31/427 , C07D413/04 , C07D413/14 , C07D417/04
摘要： The present invention provides thiazole sulfonamide and oxazole sulfonamide compounds, compositions containing the same, as well as processes for the preparation and methods for their use as pharmaceutical agents.
摘要翻译： 本发明提供噻唑磺酰胺和恶唑磺酰胺化合物，含有它们的组合物，以及其制备方法和用作药剂的方法。
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公开(公告)号：US20100075960A1
公开(公告)日：2010-03-25
申请号：US12303118
申请日：2007-05-29
申请人： Kevin Kuntz , Kyle Allen Emmitte , Tara Renae Rheault , Stephon Smith , Keith Hornberger , Hamilton Dickson , Mui Cheung
发明人： Kevin Kuntz , Kyle Allen Emmitte , Tara Renae Rheault , Stephon Smith , Keith Hornberger , Hamilton Dickson , Mui Cheung
IPC分类号： A61K31/454 , A61K31/5377 , A61K31/496 , A61K31/4545 , C07D413/14 , C07D409/14 , A61P35/00
CPC分类号： C07D409/04 , C07D409/14
摘要： The present invention provides bezimidazole thiophene compounds pharmaceutical compositions containing the same, processes for preparing the same and their use as pharmaceutical agents.
摘要翻译： 本发明提供苯扎咪唑噻吩化合物含有其的药物组合物，其制备方法及其作为药剂的用途。
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公开(公告)号：US20090124615A9
公开(公告)日：2009-05-14
申请号：US11754653
申请日：2007-05-29
申请人： Kevin Kuntz , Kyle Allen Emmitte , Tara Renae Rheault , Stephon Smith , Keith Hornberger , Hamilton Dickson , Mui Cheung
发明人： Kevin Kuntz , Kyle Allen Emmitte , Tara Renae Rheault , Stephon Smith , Keith Hornberger , Hamilton Dickson , Mui Cheung
IPC分类号： A61K31/5377 , A61K31/454 , A61K31/4545 , A61P35/00 , C07D401/14 , C07D409/14 , C07D413/14 , C07D403/14 , A61P7/00 , A61K31/496 , A61K31/513
CPC分类号： C07D409/04 , C07D409/14 , C07D413/14
摘要： The present invention provides benzimidazole thiophene compounds pharmaceutical compositions containing the same, processes for preparing the same and their use as pharmaceutical agents.
摘要翻译： 本发明提供苯并咪唑噻吩化合物，其含有它们的药物组合物，其制备方法及其作为药剂的用途。
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公开(公告)号：US20080300242A1
公开(公告)日：2008-12-04
申请号：US12128099
申请日：2008-05-28
申请人： Kevin Kuntz , David Edward Uehling , Alex Gregory Waterson , Kyle Allen Emmitte , Kirk Stevens , John Brad Shotwell , Stephon Cornell Smith , Kristen E. Nailor , James M. Salovich , Brian John Wilson , Mui Cheung , Robert Anthony Mook , Erich W. Baum , Ganesh Moorthy
发明人： Kevin Kuntz , David Edward Uehling , Alex Gregory Waterson , Kyle Allen Emmitte , Kirk Stevens , John Brad Shotwell , Stephon Cornell Smith , Kristen E. Nailor , James M. Salovich , Brian John Wilson , Mui Cheung , Robert Anthony Mook , Erich W. Baum , Ganesh Moorthy
IPC分类号： A61K31/496 , C07D401/04 , C07D279/12 , A61P35/00 , A61K31/541 , A61K31/506
CPC分类号： C07D471/04
摘要： The present invention provides imidazopyridine compounds, compositions containing the same, as well as processes for the preparation and methods for their use as pharmaceutical agents.
摘要翻译： 本发明提供咪唑并吡啶化合物，含有它们的组合物，以及其制备方法和用作药剂的方法。
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