-
公开(公告)号：US5019034A
公开(公告)日：1991-05-28
申请号：US331263
申请日：1989-03-30
CPC分类号： A61B5/14514 , A61K41/0047 , A61N1/0412 , A61N1/325 , A61N1/327 , A61B5/14532 , A61N1/0424 , A61N1/044
摘要： An electrical process for enhancing and/or controlling transport of molecules across tissue such as human and animal skin is disclosed. The process involves the use of a high voltage, short duration electrical pulses on the tissue surface to produce electroporation. Once this effect has occurred, concentration, pressure or temperature gradients, or iontopheresis can be used to move molecules across the tissue. The process can be repeatedly applied without producing undesirable tissue damage or can be used to purposely cause highly limited tissue damage for the purpose of providing a desired, relatively long term molecular transport pathway. The occurrence of the electroporation effect can be detected by monitoring the tissue for a reversible electrical breakdown, which, along with an enhanced tissue permeability, is the characteristic effect of electroporation.
摘要翻译： 公开了用于增强和/或控制分子穿过诸如人和动物皮肤的组织的电工艺。 该过程涉及在组织表面上使用高电压，短持续时间的电脉冲以产生电穿孔。 一旦发生这种影响，可以使用浓度，压力或温度梯度，或离子透析法来移动分子穿过组织。 该方法可以重复施加而不产生不期望的组织损伤，或者可以用于故意地引起高度有限的组织损伤以提供期望的相对长期的分子转运途径。 电穿孔效应的发生可以通过监测组织的可逆电击穿来检测，其与增强的组织渗透性一起是电穿孔的特征效应。
-
公开(公告)号：US4959301A
公开(公告)日：1990-09-25
申请号：US185083
申请日：1988-04-22
摘要： A process for rapidly enumerating viable biological entities is disclosed, wherein viability is determined by the critierion of growth of biological entities contained in microdroplets. Alternatively, in some cases, viability is determined by use of vital staining of biological entities contained in microdroplets. The process involves formation of microdroplets, which are very small volume liquid or gel particles, such that some of the microdroplets contain biololgical entities, followed by measurements of biological entities and of microdroplet volumes, such that use of statistical analysis can be used self-consistently to determine the number of viable entities per volume of a sample.
摘要翻译： 公开了一种用于快速计数活的生物实体的方法，其中生存力由微滴中包含的生物实体的生长指标决定。 或者，在一些情况下，通过使用包含在微滴中的生物实体的生物染色来确定存活力。 该方法包括形成微滴体，其是非常小体积的液体或凝胶颗粒，使得一些微滴含有生物实体，随后是生物体和微滴体积的测量，使得统计分析的使用可以自发地使用 以确定每体积样本的活体数。
-
搜索结果
2 条记录 (耗时 0.018 秒)
