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    Indole derivative for treating overproduction of dihydrotestosterone
    2.
    发明授权
    Indole derivative for treating overproduction of dihydrotestosterone 失效
    用于治疗二氢睾酮过量产生的吲哚衍生物

    公开(公告)号：US5760040A

    公开(公告)日：1998-06-02

    申请号：US714079

    申请日：1997-05-05

    Applicant: Kiyoshi Yoshida ,  Tadashi Kurimoto ,  Mineo Takei ,  Hiroki Sato

    Inventor： Kiyoshi Yoshida ,  Tadashi Kurimoto ,  Mineo Takei ,  Hiroki Sato

    IPC: C07D209/12 ,  A61K31/405 ,  A61K31/495 ,  C07D403/10

    CPC classification number: C07D209/12

    Abstract: The present invention relates to an indole derivative represented by formula (1) or a salt thereof, and a pharmaceutical containing the derivative or the salt: ##STR1## wherein R.sup.1 represents lower alkyl; R.sup.2 represents hydrogen or phenyl which may be substituted by at least one lower alkyl, lower alkoxy or a halogen atom; R.sup.3 represents hydrogen, lower alkyl, lower alkoxy, or phenylalkyloxy which may be substituted by halogen or lower alkyl; R.sup.4 represents hydrogen, lower alkyl or lower alkoxy; R.sup.5 represents hydrogen or lower alkyl; and n represents an integer of 1 to 5. This compound has the effects of both blocking .alpha..sub.1 -adrenergic receptors and inhibiting testosterone 5.alpha.-reductases, and is useful as a remedy and/or a preventive for diseases caused by dihydrotestosterone overproduction, such as prostatic hypertrophy, and diseases accompanying the same, such as urination disorder, male pattern alopecia, acne, and so forth.

    Abstract translation: PCT No.PCT / JP95 / 00599 Sec。 371日期：1997年5月5日 102（e）日期1997年5月5日PCT提交1995年3月29日PCT公布。 第WO95 / 26955号公报 日期：1995年10月12日本发明涉及式（1）表示的吲哚衍生物或其盐，以及含有该衍生物或其盐的药物：其中R1表示低级烷基; R2代表氢或可被至少一个低级烷基，低级烷氧基或卤原子取代的苯基; R 3表示可被卤素或低级烷基取代的氢，低级烷基，低级烷氧基或苯基烷氧基; R4代表氢，低级烷基或低级烷氧基; R5代表氢或低级烷基; 并且n表示1至5的整数。该化合物具有阻断α1-肾上腺素能受体和抑制睾酮5α-还原酶的作用，并且可用作二氢睾酮过量产生引起的疾病的补救和/或预防，例如 作为前列腺肥大，以及伴随的疾病，例如排尿障碍，男性脱发，痤疮等。

    Automatic performance device with tempo follow-up function
    7.
    发明授权
    Automatic performance device with tempo follow-up function 失效
    具有速度跟踪功能的自动演奏装置

    公开(公告)号：US4484507A

    公开(公告)日：1984-11-27

    申请号：US520177

    申请日：1983-08-04

    Applicant: Akira Nakada ,  Eisaku Okamoto ,  Kiyoshi Yoshida

    Inventor： Akira Nakada ,  Eisaku Okamoto ,  Kiyoshi Yoshida

    IPC: G10H1/26 ,  G10H1/36 ,  G10F1/00

    CPC classification number: G10H1/26 ,  G10H1/36 ,  Y10S84/12

    Abstract: An automatic performance device is of a type in which the automatic performance is executed in accordance with musical data read out successively. It comprises a fast feed stop control circuit for advancing the progress of the automatic performance when an actual key depression timing is faster than an ideal key depression timing indicated by the read out musical data and for temporarily stopping the progress when the former delays behind the latter. Comparison between the actual key depression timing and the ideal key depression timing is made by comparing the content of a counter counting the tempo pulses which decides the tempo of the automatic performance with note-length information included in the musical data. It further comprises a tempo control circuit for changing a period of the tempo pulses based on a tempo of a performance made by the actual key depression. The detection of the tempo of the performance made by the actual key depression is based on a count value of a counter counting the clock pulses whose period varies with the note-length information and presence or absence of the actual key depression. In order to prevent the period of the tempo pulses from being changed by only one great deviation of the actual key depression timing, the count value is latched at every key depression, the newest count values are kept, and the tempo detection may be made in accordance with the average value of the newest count values.

    Abstract translation: 自动演奏装置是根据连续读出的音乐数据执行自动演奏的一种类型。 它包括快速进给停止控制电路，用于当实际的按键定时比由读出的音乐数据指示的理想键按压定时更快时，推进自动演奏的进度，并且当前者延迟后者时暂时停止进度 。 通过将决定自动演奏的速度的速度脉冲的计数器的内容与包含在音乐数据中的音符长度信息进行比较来实现实际按键定时与理想按键按下定时的比较。 它还包括一个速度控制电路，用于根据由实际键按下的性能的速度来改变速度脉冲的周期。 通过实际的按键抑制对性能的检测是基于计数周期随音符长度信息和存在或不存在实际按键的时钟脉冲的计数器的计数值。 为了防止速度脉冲的周期仅由实际按键按下时间的一个很大的偏差而改变，计数值被锁定在每个键按下时，保持最新的计数值，并且可以进行速度检测 根据最新计数值的平均值。

    WATER-ABSORBING RAPIDLY DRYABLE WOVEN OR KNITTED FABRIC
    8.
    发明申请
    WATER-ABSORBING RAPIDLY DRYABLE WOVEN OR KNITTED FABRIC 审中-公开
    吸水快干织物或针织面料

    公开(公告)号：US20110059665A1

    公开(公告)日：2011-03-10

    申请号：US12991101

    申请日：2008-06-13

    Applicant: Kiyoshi Yoshida

    Inventor： Kiyoshi Yoshida

    IPC: D03D15/00 ,  D04B1/14 ,  D06P3/52

    CPC classification number: D01F8/14 ,  A41B2400/60 ,  A41D31/12 ,  D01D5/253 ,  D06M13/463 ,  D06P3/54 ,  Y10T442/3098 ,  Y10T442/431

    Abstract: A water-absorbing quick drying woven or knitted fabric characterized by containing 20% by weight or more of sheath-core type polyester fiber satisfying the following (1) to (4) requirements: (1) the fiber is a modified cross-section fiber having one or more recessed portions in its single yarn section; (2) the sheath part contains polyethylene glycol, and weight ratio of sheath part/core part is in a range of 20/80 to 50/50; (3) an amount of polyethylene glycol in the sheath-core type polyester fiber be in a range of 0.1 to 1.0% by weight; (4) long streak-like grooves A and short streak-like grooves B are present in a mixed state along the direction of fiber axis, and lengths of the streak-like grooves A and streak-like grooves B are 30 μm or more and 15 μm or more, respectively; provided that, P is a ratio of length to width of the groove, and represented by P=[Length]/[Width].

    Abstract translation: 一种吸水快干编织物，其特征在于含有20重量％以上的满足以下（1）〜（4）要求的皮芯型聚酯纤维：（1）纤维是改性的横截面纤维 在其单纱部分中具有一个或多个凹部; （2）鞘部含有聚乙二醇，鞘部/芯部的重量比在20/80〜50/50的范围内; （3）皮芯型聚酯纤维中的聚乙二醇的量为0.1〜1.0重量％的范围; （4）长条状槽A和短条纹状槽B沿着纤维轴线的方向以混合状态存在，条纹状槽A和条纹状槽B的长度为30μm以上， 15μm以上; 条件是，P是槽的长度与宽度的比，并且由P = [长度] / [宽度]表示。

    Process for producing polyphenylene ether
    9.
    发明授权
    Process for producing polyphenylene ether 有权
    生产聚苯醚的方法

    公开(公告)号：US06759507B1

    公开(公告)日：2004-07-06

    申请号：US10019076

    申请日：2001-12-26

    Applicant: Kiyoshi Yoshida ,  Naoto Ohsaki ,  Hiroya Fujii

    Inventor： Kiyoshi Yoshida ,  Naoto Ohsaki ,  Hiroya Fujii

    IPC: C08G6544

    CPC classification number: C08J11/02 ,  C08G65/44 ,  C08G65/46 ,  C08G65/485 ,  C08J3/14 ,  C08J2371/12

    Abstract: At the time of preparing polyphenylene ether resin, there can be separated and recovered efficiently an aromatic compound solvent, amines making an azeotrope with water (hereafter, referred to as ‘the amines’ for short.) and methanol. A method for producing polyphenylene ether, which comprises (a) a step for synthesizing polyphenylene ether by subjecting phenol to oxidative polymerization in the presence of a copper compound and amines in an aromatic compound solvent, (b) a step for precipitating polyphenylene ether particles by adding methanol into the solution of polyphenylene ether in the aromatic compound solvent obtained by the step (a), (c) a step for solid-liquid separating a slurry of polyphenylene ether obtained by the step (b), and then washing the separated polyphenylene ether particles with methanol to obtain the polyphenylene ether, (d) a step for adding water to a filtrate obtained by the step (c) to mix them, and then liquid-liquid separating the mixture into a phase consisting mainly of the aromatic compound and a phase consisting mainly of methanol and water, and (e) a step for supplying the phase consisting mainly of methanol and water, obtained at the step (d) to the middle portion of a distilled column to perform distillation, and separating out a distillate liquid consisting mainly of methanol, a bottom liquid consisting mainly of water and a side-cut liquid containing the amines by distillation, recycling the distillate liquid consisting mainly of methanol as methanol of the steps (b) and (c), and recycling the side-cut liquid as part of the filtrate of the step (d).

    Abstract translation: 在制备聚苯醚树脂时，可以有效地分离和回收芳族化合物溶剂，与水形成共沸物的胺（以下简称“胺”）和甲醇。一种聚苯醚的制备方法 ，其包括（a）通过在铜化合物和胺在芳族化合物溶剂中的存在下使苯酚进行氧化聚合来合成聚苯醚的步骤，（b）通过在甲醇溶液中加入甲醇使聚苯醚颗粒沉淀的步骤 通过工序（a）得到的芳香族化合物溶剂中的聚苯醚，（c）将通过工序（b）得到的聚苯醚的浆液进行固液分离的步骤，然后用甲醇洗涤分离的聚苯醚颗粒，得到 所述聚苯醚，（d）将步骤（c）中得到的滤液中加入水混合，然后将所述混合物液相分离成相组成的步骤 主要是芳族化合物和主要由甲醇和水组成的相，以及（e）将在步骤（d）获得的主要由甲醇和水组成的相供给到蒸馏塔的中间部分的步骤，以进行 蒸馏，分离主要由甲醇组成的馏出液，主要由水组成的底部液体和通过蒸馏含有胺的侧馏液，将主要由甲醇组成的馏出液循环为步骤（b）的甲醇和（ c），并且将侧切液体作为步骤（d）的滤液的一部分再循环。

    Blended dyed product of fiber dyeable with disperse dye and polyurethane fiber and dyeing method therefor
    10.
    发明授权
    Blended dyed product of fiber dyeable with disperse dye and polyurethane fiber and dyeing method therefor 失效
    用分散染料和聚氨酯纤维染色的纤维的混纺染色产品及其染色方法

    公开(公告)号：US06635347B1

    公开(公告)日：2003-10-21

    申请号：US09831946

    申请日：2001-05-16

    Applicant: Kiyoshi Yoshida

    Inventor： Kiyoshi Yoshida

    IPC: D02G300

    CPC classification number: D06P1/653 ,  D06P1/65118 ,  D06P1/65125 ,  D06P3/26 ,  D06P3/54 ,  D06P3/8204 ,  D06P3/8209 ,  D06P3/8214 ,  D06P3/8219 ,  D06P3/8271 ,  Y10S8/92 ,  Y10S8/922 ,  Y10S8/926 ,  Y10T428/2933 ,  Y10T428/2938 ,  Y10T428/2967 ,  Y10T428/2969

    Abstract: A mixed fiber article dyed with disperse dye, composed of fiber dyeable with disperse dye and polyurethane fiber, having a color fastness to a perspiration-alkali test of grade 3 or higher according to the JIS L-0848-A Method and having a surface color shade of 20 or less in terms of L value determined by spectro-colorimetry. The dyed mixed fiber article containing polyurethane fiber can be prepared by dyeing a mixed fiber article composed of disperse dyeable fiber and polyurethane fiber, such as a co-knitted fabric, either in a dye bath in the presence of polyvalent metallic compound and tannic acid or after the co-knitted fabric has been treated in a bath containing polyvalent metallic compound and tannic acid.

    Abstract translation: 由分散染料染色的由分散染料和聚氨酯纤维染色的纤维染色的混合纤维制品，具有根据JIS L-0848-A方法对3级或更高级别的耐汗碱试验的色牢度，并具有表面颜色 通过分光比色法确定的L值为20以下的色调。含有聚氨酯纤维的染色混纺纤维制品可以通过染色由分散染色纤维和聚氨酯纤维如共同针织物构成的混合纤维制品， 在多价金属化合物和单宁酸存在下的染浴中，或者在含有多价金属化合物和单宁酸的浴中处理共同编织物之后。

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