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公开(公告)号：US20070128172A1
公开(公告)日：2007-06-07
申请号：US10581606
申请日：2004-12-03
CPC分类号： A61L27/3869 , A61F2/10 , A61K35/12 , A61L27/362 , A61L27/3666 , A61L27/3813 , A61L2430/18 , C12N5/0627 , C12N2501/115
摘要： A method of enabling effective hair growth and furthermore, inducing hair growth closely similar to the natural hair state in the case of transplanting dermal papillae or cultured dermal papilla cells into the skin to regenerate the hair, characterized by comprising transplanting a composition containing the following components into an epidermis defect site: (a) dermal papillae or dermal papilla cells, (b) an epidermal tissue or epidermal cells and/or (c) a tissue constituting hair follicles or cells thereof.
摘要翻译： 此外，在将真皮乳头或培养的真皮乳头细胞移植到皮肤中以再生毛发的情况下，能够有效地进行毛发生长的方法，此外，诱导与天然毛发状态非常相似的毛发生长，其特征在于，包括移植含有以下成分的组合物 进入表皮缺损部位：（a）真皮乳头或真皮乳头细胞，（b）表皮组织或表皮细胞和/或（c）构成毛囊或其细胞的组织。
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公开(公告)号：US20100197019A1
公开(公告)日：2010-08-05
申请号：US11992753
申请日：2006-10-02
CPC分类号： C12N5/0627 , C12N2501/115 , C12N2501/135
摘要： A method for culture of hair follicular dermal sheath cells or precursor cells thereof which are potent cellular materials for such as hair regeneration by cell transplantation is provided. That is, by performing culture in an animal cell culture medium supplemented with platelet-derived growth factor AA (PDGF-AA) and fibroblast growth factor 2 (FGF2), hair follicular dermal sheath cells are proliferated while sustaining their function, or hair follicular dermal sheath precursor cells are differentiated into dermal sheath cells and proliferated.
摘要翻译： 提供了通过细胞移植进行毛发再生的有效细胞材料的毛囊皮肤细胞或其前体细胞的培养方法。 也就是说，通过在补充有血小板衍生生长因子AA（PDGF-AA）和成纤维细胞生长因子2（FGF2）的动物细胞培养基中进行培养，毛囊真皮鞘细胞在维持其功能的同时增殖，或毛囊皮肤 鞘前体细胞分化成皮肤鞘细胞并增殖。
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公开(公告)号：US08206980B2
公开(公告)日：2012-06-26
申请号：US11992753
申请日：2006-10-02
CPC分类号： C12N5/0627 , C12N2501/115 , C12N2501/135
摘要： A method for culture of hair follicular dermal sheath cells or precursor cells thereof which are potent cellular materials for such as hair regeneration by cell transplantation is provided. That is, by performing culture in an animal cell culture medium supplemented with platelet-derived growth factor AA (PDGF-AA) and fibroblast growth factor 2 (FGF2), hair follicular dermal sheath cells are proliferated while sustaining their function, or hair follicular dermal sheath precursor cells are differentiated into dermal sheath cells and proliferated.
摘要翻译： 提供了通过细胞移植进行毛发再生的有效细胞材料的毛囊皮肤细胞或其前体细胞的培养方法。 也就是说，通过在补充有血小板衍生生长因子AA（PDGF-AA）和成纤维细胞生长因子2（FGF2）的动物细胞培养基中进行培养，毛囊真皮鞘细胞在维持其功能的同时增殖，或毛囊皮肤 鞘前体细胞分化成皮肤鞘细胞并增殖。
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公开(公告)号：US20100166719A1
公开(公告)日：2010-07-01
申请号：US12656139
申请日：2010-01-19
CPC分类号： A61L27/3869 , A61F2/10 , A61K35/12 , A61L27/362 , A61L27/3666 , A61L27/3813 , A61L2430/18 , C12N5/0627 , C12N2501/115
摘要： A method of enabling effective hair growth and furthermore, inducing hair growth closely similar to the natural hair state in the case of transplanting dermal papillae or cultured dermal papilla cells into the skin to regenerate the hair, characterized by comprising transplanting a composition containing the following components into an epidermis defect site: (a) dermal papillae or dermal papilla cells, (b) an epidermal tissue or epidermal cells and/or (c) a tissue constituting hair follicles or cells thereof.
摘要翻译： 此外，在将真皮乳头或培养的真皮乳头细胞移植到皮肤中以再生毛发的情况下，能够有效地进行毛发生长的方法，此外，诱导与天然毛发状态非常相似的毛发生长，其特征在于，包括移植含有以下成分的组合物 进入表皮缺损部位：（a）真皮乳头或真皮乳头细胞，（b）表皮组织或表皮细胞和/或（c）构成毛囊或其细胞的组织。
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